Do centro-oeste brasileiro ao norte português: experiência(s) com a Terapia Comunitária Integrativa

This text seeks to describe the main actions with Integrative Community Therapy (TCI), from 2017 to 2019, from Cuiabá – MT, in central-western Brazil, to the city of Bragança, in northern Portugal, pointing out the diversity of groups served, as well as the culture and age group as elements to be considered for the effectiveness of the therapy circle. Furthermore, this work aims to contribute to the dissemination of the TCI, pointing to future possibilities of research or serving as background/data to it.Este texto busca describir las principales acciones con Terapia Comunitaria Integrativa (TCI), de 2017 a 2019, desde Cuiabá – MT, en el centro-oeste de Brasil, hasta la ciudad de Bragança, en el norte de Portugal, señalando la diversidad de grupos atendidos, así en cuanto a la cultura y el grupo de edad como elementos a considerar, para la efectividad de la rueda terapéutica. Además, este trabajo tiene como objetivo contribuir a la difusión de las TCI, apuntando a futuras posibilidades de investigación o sirviendo como fondo / base / datos para la misma.Busca-se nesse texto descrever as principais ações com a Terapia Comunitária Integrativa, de 2017 a 2019, desde Cuiabá – MT, no centro-oeste brasileiro, até a cidade de Bragança, no norte português, apontando para a diversidade de grupos atendidos, bem como para a cultura e a faixa etária como elementos a serem considerados, para a efetividade da roda de terapia. Ademais, esse trabalho objetiva contribuir com a divulgação da TCI, apontando para possiblidades futuras de pesquisa ou servindo como fundo/base/dado, para a mesma

Initiation to Scientific Research: Notes from a Beginner to Other Young Researchers

Intenta-se nesse trabalho apresentar nossa experiência na realização de uma pesquisa qualitativa, no âmbito da graduação em Saúde Coletiva, na Universidade Federal de Mato Grosso, Brasil, entre 2017 e 2019, cujo objetivo era compreender como profissionais de saúde de cuidados primários, de um bairro da periferia da cidade de Cuiabá, estado de Mato Grosso, significavam a violência e, a partir daí, construíam suas práticas de enfrentamento ao fenómeno. Interessa-nos, aqui, compartilhar nosso percurso, de modo a auxiliar jovens pesquisadores na condução de suas pesquisas, apontando para eventuais obstáculos, possíveis estratégias de manejo e modos de atuação.The aim of this work is to present our experience in conducting a qualitative research, within the scope of the undergraduate programme in Collective Health, at the Federal University of Mato Grosso, Brazil, between 2017 and 2019. Its objective was to understand how primary healthcare professionals, from a neighborhood on the outskirts of the city of Cuiabá, state of Mato Grosso, assessed violence and how, from there, they built their practices to face the phenomenon. We are interested in sharing our path in order to assist young researchers in conducting their research, indicating possible obstacles, management strategies and courses of action.info:eu-repo/semantics/publishedVersio

Project Links: mental health promotion with integrative community therapy – experience report

A Terapia Comunitária Integrativa (TCI) é um instrumento terapêutico brasileiro que se constitui como um espaço de convivência sociocultural, no qual as pessoas podem ouvir e falar, acolher e compartilhar problemas geradores de sofrimento quotidiano. Em articulação com a Associação dos estudantes brasileiros de uma instituição de ensino superior do norte de Portugal, foi desenvolvido o projeto Laços que decorreu entre outubro e dezembro de 2018. O presente estudo tem como objetivo descrever esse Projeto, que visou oferecer sessões de TCI para os estudantes. As rodas de terapia tiveram uma adesão relativa de estudantes, todavia, em todas elas houve pelo menos um participante novo. Os encontros foram realizados uma vez na semana, no período noturno. Os sentimentos partilhados, na sua maioria, advinham do quotidiano académico ou eram provocados pelo mesmo. Considera-se que a TCI, por meio do desenvolvimento do projeto Laços foi, na perspetiva dos estudantes, um efetivo instrumento de cuidado e promoção da saúde mental.The Integrative Community Therapy (ICT) is a Brazilian therapeutic instrument that is constituted as a space of sociocultural coexistence, in which people can listen and talk, receive and share problems that generate daily suffering. In conjunction with the Brazilian Students Association of a higher education institution in northern Portugal, it was developed Laços project between October and December 2018. Meetings occurred once a week, in the evening. This paper describes the Laços project, which aimed to offer ICT meetings to students. The therapy wheels had a relative enrollment of students, however in all of them there was at least one new participant. Most of the shared feelings came from, or were caused by academic daily life. From students’ point of view, ICT, by the development of the Laços Project, is considered to be an effective instrument of care and promotion of mental health.info:eu-repo/semantics/publishedVersio

SAÚDE COLETIVA EM MATO GROSSO: NOTAS SOBRE A REMASCO

O Instituto de Saúde Coletiva da Universidade Federal de Mato Grosso promove a formação em Saúde Coletiva, desde 1993, no âmbito da pós-graduação e, a partir de 2010, em nível de graduação, o que fomentou a criação da Semana Acadêmica de Saúde Coletiva, em 2011, e do Encontro Estadual de Saúde Coletiva (ENESCO MT), em 2017. Este trabalho tece algumas notas sobre a Reunião Científica dos Estudantes Matogrossenses de Saúde Coletiva (REMASCO), criada e realizada em 2020, enquanto atividade pré-evento do ENESCO e como um espaço de aglutinação e interlocução entre estudantes da área. Destarte, aponta para a potencialidade da ação que, assentada na extensão universitária e no aporte da promoção da saúde, instaura-se como espaço de divulgação de informação/conhecimento de/sobre saúde

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Ruthenium(II) complexes with hydroxypyridinecarboxylates: screening potential metallodrugs against Mycobacterium tuberculosis

Three promising antimycobacterium tuberculosis ruthenium(II) complexes with the deprotonated ligands 2-hydroxynicotinic acid (2-OHnicH), 6-hydroxynicotinic acid (6-OHnicH) and 3-hydroxypicolinic acid (3-OHpicH) were synthesized and characterized. Structural analysis revealed three different coordination modes depending of the hydroxypyridinecarboxylate ligand. In the complex [Ru(2-OHnic)(dppb)(bipy)PF6 (1), the 2-OHnic anion is coordinated by the O,O-chelating mode (via carboxylate group and phenolate oxygen), in the Ru(6-OHnic)(dppb)(bipy)]PF6 (2) a O-O chelation by the carboxylate group is observed for the 6-OHnic ligand and for the complex [Ru(3-OHpic)(dppb)(bipy))PF6 (3) a N,O-chelating mode (via carboxylate) occurs to the 3-OHpic anion. The compounds were evaluated for activity against Mycobacterium tuberculosis H(37)Rv ATCC 27294 using Resazurin Microtitre Assay (REMA) plate method and cytotoxicity in VERO CCL-81 cell line. All the synthesized compounds exhibited good antimycobacterial activity and a completely lack of cytotoxicity activity, indicating a good selectivity index. (C) 2014 Elsevier Ltd. All rights reserved.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

New ruthenium(II)/phosphines/diimines complexes: promising antitumor (human breast cancer) and Mycobacterium tuberculosis fighting agents

The synthesis and characterization of ruthenium compounds of the type [RuCl2(P)2(N–N)] [(P)2 = (PPh3)2, dppb = 1,4-bis(diphenylphosphino)butano; dppp = 1,3-bis(diphenylphosphino)propane; N–N = 5,5'- dimethyl-2,2'dipyridyl (5,5'-mebipy) or 4,4'-dimethyl-2,2'dipyridyl (4,4'-mebipy)] are described. The complexes were characterized using elemental analysis, UV–Vis and infrared spectroscopies, cyclic voltammetry, and X-ray crystallography. In vitro evaluation of the complexes, using the MTT methodology, revealed their cytotoxic activities in a range of 5.4–15.7 lM against the MDA-MB-231 breast tumor cells and showed that, in this case, they are more active than the reference metallodrug cisplatin. The in vitro antimycobacterial activities of the complexes had their Minimum Inhibitory Concentration (MIC) for MTB cell growth measured, by the REMA method. The MICs for these complexes were found to be between 12.5 and 25.0 lg/mL. The results are comparable with the ‘‘second line’’ drug cycloserine (MIC = 12.5– 50.0 lg/mL), commonly used in the treatment of TB.CNPqCAPESFAPESPFAPERJCYTE