Acute appendicitis following blunt abdominal trauma. Coincidence or causality?

La apendicitis aguda es una enfermedad frecuente en la práctica clínica; entre sus causas bien definidas están la obstrucción luminal por fecalitos, la hiperplasia linfoide, los cuerpos extraños y los parásitos intestinales. El trauma abdominal cerrado se ha asociado como un factor etiológico de esta enfermedad; sin embargo, su relación causal aún no es clara. En el presente artículo, se presenta el caso de un paciente con apendicitis posterior a trauma abdominal cerrado.Acute appendicitis is a common disease in clinical practice; some well-defined causes include luminal obstruction by fecoliths, lymphoid hyperplasia, foreign bodies and intestinal parasites. Closed abdominal trauma has been associated as an etiological factor, although, their causal relationship is still unclear. This paper presents the case of a patient with appendicitis after a closed abdominal trauma

Administración y control de los servicios de infraestructura it bajo el sistema operativo ZENTYAL server 6.2

El trabajo realizado en este documento representa lo que se ha aprendido durante el desarrollo del diplomado de profundización de Linux, en el cual se aprendió a administrar y gestionar usuarios por medio de la estructuración de permisos, administrando los recursos del sistema operativo GNU/Linux. Se realizo un enfoque en todo lo relacionado a la administración de sistemas informáticos. Para la solución de este paso se utilizó software como VirtualBox para la virtualización de las máquinas, la imagen ISO de Zentyal versión 6.2 y una distribución de Linux para conectarse como cliente, en este caso se usó Linux Mint y Ubuntu Desktop. En el presente informe se realiza la administración y control de una distribución, pero enfocada a la implementación de servicios de infraestructura IT de mayo nivel para intranet y extranet en instituciones complejas.The work carried out in this document represents what has been learned during the development of the Linux deepening diploma, in which it was learned to administer and manage users through the structuring of permissions, managing the resources of the GNU / Linux operating system. A focus was made on everything related to the administration of computer systems. For the solution of this step, software such as VirtualBox was used to virtualize the machines, the ISO image of Zentyal version 6.2 and a Linux distribution to connect as a client, in this case Linux Mint and Ubuntu Desktop were used. In this report, the administration and control of a distribution is carried out, but focused on the implementation of IT infrastructure services at the highest level for intranet and extranet in complex institutions

Dating historical droughts from religious ceremonies, the international pro pluvia rogation database

Climate proxy data are required for improved understanding of climate variability and change in the pre-instrumental period. We present the first international initiative to compile and share information on pro pluvia rogation ceremonies, which is a well-studied proxy of agricultural drought. Currently, the database has more than 3500 dates of celebration of rogation ceremonies, providing information for 153 locations across 11 countries spanning the period from 1333 to 1949. This product provides data for better understanding of the pre-instrumental drought variability, validating natural proxies and model simulations, and multi-proxy rainfall reconstructions, amongst other climatic exercises. The database is freely available and can be easily accessed and visualized via http://inpro.unizar.es/.info:eu-repo/semantics/publishedVersio

A global drought monitoring system and dataset based on ERA5 reanalysis: A focus on crop-growing regions

14 Pags.- 12 Figs. © 2022 The Authors. Geoscience Data Journal published by Royal Meteorological Society and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License.Drought monitoring systems are real-time information systems focused on drought severity data. They are useful for determining the drought onset and development and defining the spatial extent of drought at any time. Effective drought monitoring requires databases with high spatial and temporal resolution and large spatial and temporal coverage. Recent reanalysis datasets meet these requirements and offer an excellent alternative to observational data. In addition, reanalysis data allow better quantification of some variables that affect drought severity and are more seldom observed. This study presents a global drought dataset and a monitoring system based on the Standardized Precipitation Evapotranspiration Index (SPEI) and ERA5 reanalysis data. Computation of the atmospheric evaporative demand for the SPEI follows the FAO-56 Penman-Monteith equation. The system is updated weekly, providing near real-time information at a 0.5° spatial resolution and global coverage. It also contains a historical dataset with the values of the SPEI at different time scales since January 1979. The drought monitoring system includes the assessment of drought severity for dominant crop-growing areas. A comparison between SPEI computed from the ERA5 and CRU datasets shows generally good spatial and temporal agreement, albeit with some important differences originating mainly from the different spatial patterns of SPEI anomalies, as well as from employing long-term climate trends for different regions worldwide. The results show that the ERA5 dataset offers robust results and supports its use for drought monitoring. The new system and dataset are publicly available at the link https://global-drought-crops.csic.es/.This work was supported by projects PCI2019-103631 financed by the Spanish Commission of Science and Technology and FEDER and CROSSDRO project funded by AXIS (Assessment of Cross [X]- sectoral climate Impacts and pathways for Sustainable transformation), JPI- Climate co- funded call of the European Commission.Peer reviewe

Research on heart failure in Colombia 1980-2015: a systematic review

Introduction: Heart failure is one of the most prevalent diseases worldwide. In Colombia, the state of research on the subject is unknown.Objective: To describe the original publications on heart failure in Colombia.Materials and methods: Systematic review. Digital search in Embase, PubMed, LILACS and Scielo, using the MeSH terms: “heart failure”, “Colombian”, “Colombia”, “Latin America”, “developing countries”. Manual search of 58 journals identified in Publindex. Original research that evaluated adult Colombians with heart failure and published between 1980 and 2015 were included.Results: 2 684 articles were identified, of which 35 met the inclusion criteria. 30 (85.7%) were published since 2009, 30 (85.7%) were conducted in Bogotá and Medellín, 11 (31.4%) had n200, 19 (54.2%) were descriptive and 5 (14.2%) quasi-experimental. Moreover, 9 (25.7%) described general populations, 9 (25.7%) addressed the issue of self-care, 3 (8.8%) cardiac rehabilitation, 3 (8.8%) perception of the disease and 3 (8.8%) prognostic factors.Conclusions: The amount of published original research on heart failure is low, and most of them were carried out recently. Descriptive design was the most frequent, while the most frequently addressed topics were self-care and population descriptions.Introducción. La falla cardíaca es una de las enfermedades con mayor prevalencia a nivel mundial. En Colombia no se conoce con certeza el estado de la investigación en torno al tema.Objetivo. Describir las publicaciones originales en falla cardíaca en Colombia.Materiales y métodos. Revisión sistemática. Búsqueda electrónica en Embase, PubMed, LILACS Y SciELO, con términos MeSH: “heart failure”, “colombian”, “Colombia”, “Latin America”, “developing countries”. Búsqueda manual en 58 revistas identificadas en Publindex. Se incluyeron investigaciones originales, publicadas entre 1980 y 2015, que evaluaron población adulta colombiana con falla cardíaca.Resultados. Se identificaron 2 684 artículos: 35 cumplieron criterios de inclusión; 30 (85.7%) fueron publicados a partir del 2009; 30 (85.7%) se realizaron en Bogotá y Medellín; 11 (31.4%) tuvieron n200; 19 (54.2%) fueron descriptivos y 5 (14.2%) cuasiexperimentales; 9 (25.7%) describieron poblaciones generales; 9 (25.7%) abordaron el tema del autocuidado, 3 (8.8%), la rehabilitación cardíaca, 3 (8.8%), la percepción de enfermedad y 3 (8.8%), los factores pronósticos.Conclusión. El número de investigaciones originales publicadas sobre falla cardíaca es escaso; la mayoría se realizó en los últimos años. El diseño descriptivo fue el más común. Los temas abordados con mayor frecuencia fueron el autocuidado y las descripciones poblacionales

Research on heart failure in Colombia 1980-2015: a systematic review

Introduction: Heart failure is one of the most prevalent diseases worldwide. In Colombia, the state of research on the subject is unknown.Objective: To describe the original publications on heart failure in Colombia.Materials and methods: Systematic review. Digital search in Embase, PubMed, LILACS and Scielo, using the MeSH terms: “heart failure”, “Colombian”, “Colombia”, “Latin America”, “developing countries”. Manual search of 58 journals identified in Publindex. Original research that evaluated adult Colombians with heart failure and published between 1980 and 2015 were included.Results: 2 684 articles were identified, of which 35 met the inclusion criteria. 30 (85.7%) were published since 2009, 30 (85.7%) were conducted in Bogotá and Medellín, 11 (31.4%) had n200, 19 (54.2%) were descriptive and 5 (14.2%) quasi-experimental. Moreover, 9 (25.7%) described general populations, 9 (25.7%) addressed the issue of self-care, 3 (8.8%) cardiac rehabilitation, 3 (8.8%) perception of the disease and 3 (8.8%) prognostic factors.Conclusions: The amount of published original research on heart failure is low, and most of them were carried out recently. Descriptive design was the most frequent, while the most frequently addressed topics were self-care and population descriptions.Introducción. La falla cardíaca es una de las enfermedades con mayor prevalencia a nivel mundial. En Colombia no se conoce con certeza el estado de la investigación en torno al tema.Objetivo. Describir las publicaciones originales en falla cardíaca en Colombia.Materiales y métodos. Revisión sistemática. Búsqueda electrónica en Embase, PubMed, LILACS Y SciELO, con términos MeSH: “heart failure”, “colombian”, “Colombia”, “Latin America”, “developing countries”. Búsqueda manual en 58 revistas identificadas en Publindex. Se incluyeron investigaciones originales, publicadas entre 1980 y 2015, que evaluaron población adulta colombiana con falla cardíaca.Resultados. Se identificaron 2 684 artículos: 35 cumplieron criterios de inclusión; 30 (85.7%) fueron publicados a partir del 2009; 30 (85.7%) se realizaron en Bogotá y Medellín; 11 (31.4%) tuvieron n200; 19 (54.2%) fueron descriptivos y 5 (14.2%) cuasiexperimentales; 9 (25.7%) describieron poblaciones generales; 9 (25.7%) abordaron el tema del autocuidado, 3 (8.8%), la rehabilitación cardíaca, 3 (8.8%), la percepción de enfermedad y 3 (8.8%), los factores pronósticos.Conclusión. El número de investigaciones originales publicadas sobre falla cardíaca es escaso; la mayoría se realizó en los últimos años. El diseño descriptivo fue el más común. Los temas abordados con mayor frecuencia fueron el autocuidado y las descripciones poblacionales

Prescripción de analgésicos y reacciones adversas en pacientes hospitalizados

Justificación. El dolor tiene alta prevalencia en la población general, siendo mayor en pacientes hospitalizados, con cifras cercanas al 80%. El control del dolor no siempre es adecuado debido a varios factores, siendo uno de los más importantes, el escasoconocimiento en el manejo de los analgésicos. Como una de las primeras medidasde mejoramiento asistencial para reducir el dolor en un hospital, debe conocerse la prevalencia de este síntoma y, asimismo, debe analizarse el abordaje terapéutico realizado.Es por esto por lo que este estudio tuvo como objetivo analizar el uso de analgésicos en pacientes de un hospital de cuarto nivel en Bogotá, Colombia, identificar los analgésicos más utilizados, el rango de dosis, las posibles interacciones y reacciones adversas a medicamentos (RAM) existentes. Resultados. El 78,9% de los pacienteshospitalizados presentaban dolor. Se prescribió analgésicos en 561 pacientes hospitalizados.Entre los más utilizados se encuentran: el acetaminofén (33,3%) y eltramadol (29,7%). El rango de duración de la terapia analgésica más común fue de 1 a 5 días (81,7%). Se identificaron 37 casos de sobredosificación y tres de terapia duplicada. Se presentaron 28 casos de reacciones adversas a medicamento (RAM).Discusión. El adecuado tratamiento del dolor cobra vital importancia al evaluar la satisfacción del paciente. Se encuentran diferentes tendencias de uso de analgésicos en pacientes hospitalizados, siendo los más utilizados el acetaminofén y los antiinflamatoriosno esteroideos (AINE). Se debe seguir investigando en este tema para tener evidencias científicas más firmes que permitan dictar unos lineamientos de aplicación universal para un correcto alivio del dolor.Justification. Pain has a high prevalence in the general population, being higher in inpatient, with figures close to 80%. Pain management is not always suitable due to several factors, one of the most important the lack of knowledge in the managementof analgesics. One of the first measures of improving care to reduce pain in a hospital should be determine the prevalence of this symptom and analyze the therapeutical proach performed. That is why the aim of this study was to analyze the use of analgesics in patients of a fourth-level hospital in Bogotá, Colombia, identify the mostcommonly used analgesics, range of doses, possible interactions and adverse drugs reactions. Results. The 78.9% of the patients were pain. Analgesics were prescribed in 561 hospitalized patients. The most used were acetaminophen (33.3%) and tramadol(29.7%). The most common range of duration of analgesic therapy was 1-5 days (81.7%). 37 cases of overdosing and 3 cases of duplicate therapy were identified. 28 cases of adverse drug reactions (ADRs) were presented. Discussion. Proper treatmentof pain plays a vital role in assessing patient satisfaction. There are different trends analgesic use in inpatient, being the most used acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs). It should further investigate on this issueto have stronger scientific evidence to dictate a universal application guidelines forproper pain relief

Las Tic, la innovación en el aula y sus impactos en la educación superior

El avance acelerado de la tecnología en la sociedad actual hace que, continuamente, se esté repensando la forma de llevar a cabo las actividades formativas en los diferentes campos del saber con el fin de obtener métodos más eficientes, eficaces e innovadores. Esta avalancha de cambios también invade al entorno educativo y obliga a que la sociedad se plantee una serie de interrogantes que cuestionan todos los ámbitos de la labor docente. La influencia en el ámbito educativo no solamente se limita al impacto que tiene el desarrollo de nuevas aplicaciones y programas en la labor del proceso de enseñanza-aprendizaje, sino que también debe reconocerse el impacto que tiene sobre el currículo la incursión de nuevas técnicas, tecnologías y softwares, dado que modifican las competencias requeridas para el ejercicio profesional. Este trabajo contó con el apoyo de los grupos de investigación: INVEDUSA, LIOS, LUMEN y Joaquín Aarón Manjarrés

Expression of Interest: The Canfranc Axion Detection Experiment (CADEx)

Trabajo presentado al 29th Meeting of the LSC Scientific Committee, celebrado online del 30 de noviembre al 1 de diciembre de 2021.Peer reviewe

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio