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ITQs and Property Rights: A review of Australian case law
This paper discusses the legal concepts of property and property rights and examines how the Australian courts perceive fishing entitlements (licences, ITQs and Individual Effort Units). On the basis of case law concerning the nature of other fishing entitlements, such as fishing licences, the courts are likely to find that ITQs are proprietary in nature. However the Australian courts have found that fishing entitlements, although similar in terms of the privileges conferred, are not the common law property right of profit á prendre. They are a statutory entitlement. Compensation for modification and extinguishment of these rights depends on whether there is compensation payable under applicable legislation or on whether the plaintiffs can rely on constitutional guarantees of acquisition of property on just terms. The courts have clearly indicated that fishing entitlements are rights created by government as means of regulating the fishing industry and are thus governed by the legislation that created them. By annulling that legislation, the entitlement no longer exists. By modifying the legislation, the entitlement is redefined. However, until there is a relevant Australian case on ITQs, it remains to be seen whether the courts will view them any differently to other fishing entitlementsKeywords: Individual Transferable Quotas, property rights, Australian ITQ fisherie
Multivariate order statistics via multivariate concomitants
AbstractLet X¯1,…,X¯n denote a set of n independent identically distributed k-dimensional absolutely continuous random variables. A general class of complete orderings of such random vectors is supplied by viewing them as concomitants of an auxiliary random variable. The resulting definitions of multivariate order statistics subsume and extend orderings that have been previously proposed such as norm ordering and N-conditional ordering. Analogous concepts of multivariate record values and multivariate generalized order statistics are also described
Mobilizing the emergence of Phronetic TechnoScienceSocieties:low-carbon e-mobility in China
TechnoScienceSociety (TSS) spells the wholesale reorganization of the constellation of related concepts that together make up the very common-sense meaning of ‘politics’ and ‘government’, not least of which today are knowledge, science, technology and society, all of which are currently founded on essentially literal, dualistic not pragmatic, processual grounds. We argue that grappling with TSS and a politics of TSS demands a shift broadly from a universalist (if possibly critical) epistemo-politics of critique or criticism to an onto-politics of situated practical wisdom (phronesis). Important pointers in this direction come from existing work in actor network theory (ANT)-inspired STS. But while useful starting points, this work is also insufficient in some key regards, to the point that we must now move beyond it. In particular, the need for a shift to a situated, processual and practically engaged perspective applies no less to discussions such as this in STS. We here trace out some of the argument for, and consequences of, that move. The argument proceeds as follows. First we consider the after-ANT argument of ontological politics and how this demands a break with the familiar epistemological and ‘one world’ politics still dominating contemporary discourse, mainstream and critical. Then we consider some of the key problems with this conception of ontological politics vis-à-vis the predicament of an emerging TSS. This includes a brief discussion of an alternative perspective, of complex power/knowledge systems (CP/KS) within a phronetic onto-politics. Finally, we illustrate the arguments by analysing, using this CP/KS and onto-political perspective, a key case study of contemporary TSS: the ongoing attempts of innovation towards a transition in urban mobility system in China
The progress made in determining the Mycobacterium tuberculosis structural proteome
Mycobacterium tuberculosis is a highly infectious pathogen that is still responsible for millions of deaths annually. Effectively treating this disease typically requires a course of antibiotics, most of which were developed decades ago. These drugs are, however, not effective against persistent tubercle bacilli and the emergence of drug-resistant stains threatens to make many of them obsolete. The identification of new drug targets, allowing the development of new potential drugs, is therefore imperative. Both proteomics and structural biology have important roles to play in this process, the former as a means of identifying promising drug targets and the latter allowing understanding of protein function and protein–drug interactions at atomic resolution. The determination of M. tuberculosis protein structures has been a goal of the scientific community for the last decade, who have aimed to supply a large amount of structural data that can be used in structure-based approaches for drug discovery and design. Only since the genome sequence of M. tuberculosis has been available has the determination of large numbers of tuberculosis protein structures been possible. Currently, the molecular structures of 8.5% of all the pathogen's protein-encoding ORFs have been determined. In this review, we look at the progress made in determining the M. tuberculosis structural proteome and the impact this has had on the development of potential new drugs, as well as the discovery of the function of crucial mycobaterial proteins
Who Commits to the Rule of Law? Constrained Government and Foreign Direct Investment in Postcommunist States
Research linking credible commitments to the rule of law in terms of property rights and contract enforcement is a hallmark of recent efforts to explain economic growth and development. However, many postcommunist states have had difficulty making such commitments and spurring growth. Many argue political polarization prevents states from reforming laws and protecting property rights in some countries whereas single-party governance renders state promises incredible in others. I analyze pooled cross-sectional time-series data for twenty-four postcommunist countries and provide evidence effective constraints among elected officials act as democratic commitment mechanisms rendering government policies credible
Bim Nuclear Translocation and Inactivation by Viral Interferon Regulatory Factor
Viral replication efficiency is in large part governed by the ability of viruses to counteract pro-apoptotic signals induced by infection of the host cell. Human herpesvirus 8 (HHV-8) uses several strategies to block the host's innate antiviral defenses via interference with interferon and apoptotic signaling. Contributors include the four viral interferon regulatory factors (vIRFs 1–4), which function in dominant negative fashion to block cellular IRF activities in addition to targeting IRF signaling-induced proteins such as p53 and inhibiting other inducers of apoptosis such as TGFβ receptor-activated Smad transcription factors. Here we identify direct targeting by vIRF-1 of BH3-only pro-apoptotic Bcl-2 family member Bim, a key negative regulator of HHV-8 replication, to effect its inactivation via nuclear translocation. vIRF-1-mediated relocalization of Bim was identified in transfected cells, by both immunofluorescence assay and western analysis of fractionated cell extracts. Also, co-localization of vIRF-1 and Bim was detected in nuclei of lytically infected endothelial cells. In vitro co-precipitation assays using purified vIRF-1 and Bim revealed direct interaction between the proteins, and Bim-binding residues of vIRF-1 were mapped by deletion and point mutagenesis. Generation and experimental utilization of Bim-refractory vIRF-1 variants revealed the importance of vIRF-1:Bim interaction, specifically, in pro-replication and anti-apoptotic activity of vIRF-1. Furthermore, blocking of the interaction with cell-permeable peptide corresponding to the Bim-binding region of vIRF-1 confirmed the relevance of vIRF-1:Bim association to vIRF-1 pro-replication activity. To our knowledge, this is the first report of an IRF protein that interacts with a Bcl-2 family member and of nuclear sequestration of Bim or any other member of the family as a means of inactivation. The data presented reveal a novel mechanism utilized by a virus to control replication-induced apoptosis and suggest that inhibitory targeting of vIRF-1:Bim interaction may provide an effective antiviral strategy
Assessment of resolution and intercenter reproducibility of results of genotyping Staphylococcus aureus by pulsed-field gel electrophoresis of SmaI macrorestriction fragments: a multicenter study
Twenty well-characterized isolates of methicillin-resistant Staphylococcus
aureus were used to study the optimal resolution and interlaboratory
reproducibility of pulsed-field gel electrophoresis (PFGE) of DNA
macrorestriction fragments. Five identical isolates (one PFGE type), 5
isolates that produced related PFGE subtypes, and 10 isolates with unique
PFGE patterns were analyzed blindly in 12 different laboratories by
in-house protocols. In several laboratories a standardized PFGE protocol
with a commercial kit was applied successfully as well. Eight of the
centers correctly identified the genetic homogeneity of the identical
isolates by both the in-house and standard protocols. Four of 12
laboratories failed to produce interpretable data by the standardized
protocol, due to technical problems (primarily plug preparation). With the
five rel
Competition, efficiency and soundness in European life insurance markets
This paper provides cross-country evidence on the association between soundness and competition in the life insurance industry, where competition is measured by the Boone indicator. We analyze 10 European Union (EU) life insurance markets over the post-deregulation period 1999-2011. The results indicate that competition increases the soundness of the EU life insurance markets. Since the Boone indicator measures competition based on the reallocation of profits from inefficient insurers to efficient ones, our results suggest that efficiency is the mechanism through which competition contributes to insurer solvency. The soundness-enhancing effect of competition is greater for weak insurers than for healthy ones
The use of 4D-CTA in the diagnostic work-up of brain arteriovenous malformations
Neuro Imaging Researc
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