The Relationship Between Emotional Intelligence and Internet Addiction Among Youth and Adults

This study aimed to compare emotional intelligence (EI) levels and Internet addiction (IA) by gender and age groups and to assess the predictive relationship between EI and IA. One thousand four hundred thirteen young people and adults participated in the study. Participants were between 17 and 81 years old (M = 38.70 years old, SD = 13.72 years old); 42.2% were male, whereas 57.5% were female. We used a sociodemographic questionnaire, the Schutte Emotional Intelligence Scale (Schutte, Malouff, & Bhullar, 2009), and the Internet Addiction Test (Young, 1998) as data collection instruments. Results showed that there is a weak, but statistically significant, negative relationship between EI and IA. We found higher levels of EI in older people and in women than in the youngest participants and in men. No relevant prevalence of IA was found in the participants of this study.info:eu-repo/semantics/publishedVersio

Influence of ultrasound stimulation on the viability, proliferation and protein expression of osteoblasts and periodontal ligament fibroblasts

Among the adjunctive procedures to accelerate orthodontic tooth movement (OTM), ultrasound (US) is a nonsurgical form of mechanical stimulus that has been explored as an alternative to the currently available treatments. This study aimed to clarify the role of US in OTM by exploring different stimulation parameters and their effects on the biological responses of cells involved in OTM. Human fetal osteoblasts and periodontal ligament fibroblasts cell lines were stimulated with US at 1.0 and 1.5 MHz central frequencies and power densities of 30 and 60 mW/cm2 in continuous mode for 5 and 10 min. Cellular proliferation, metabolic activity and protein expression were analyzed. The US parameters that significantly improved the metabolic activity were 1.0 MHz at 30 mW/cm2 for 5 min and 1.0 MHz at 60 mW/cm2 for 5 and 10 min for osteoblasts; and 1.0 MHz at 30 mW/cm2 for 5 min and 1.5 MHz at 60 mW/cm2 for 5 and 10 min for fibroblasts. By stimulating with these parameters, the expression of alkaline phosphatase was maintained, while osteoprotegerin synthesis was induced after three days of US stimulation. The US stimulation improved the biological activity of both osteoblasts and periodontal ligament fibroblasts, inducing their osteogenic differentiation.This in vitro study was supported by FCT (Fundação para a Ciência e Tecnologia) in the scope of the grants UI/BD/150951/2021 and UI/BD/09375/2020, the funding contract 2020.00215.CEECIND (DOI: 10.54499/2020.00215.CEECIND/CP1600/CT0009) and through the projects UIDB/04436/2020, UIDP/04436/2020, FunFibRai—PTDC/EME-EME/4197/2021 (DOI: 10.54499/PTDC/EME-EME/4197/ 2021), BrainStimMap—PTDC/EME-EME/1681/2021 (DOI: 10.54499/PTDC/EME-EME/1681/2021), AlignAgen-GI2-CESPU-2022 and UID/CTM/00264/2021 project of 2C2T under the COMPETE and FCT/MCTES (PIDDAC), co-financed by FEDER through the PT2020 program

Optimization of a photobiomodulation protocol to improve the cell viability, proliferation and protein expression in osteoblasts and periodontal ligament fibroblasts for accelerated orthodontic treatment

Numerous pieces of evidence have supported the therapeutic potential of photobiomodulation (PBM) to modulate bone remodeling on mechanically stimulated teeth, proving PBM's ability to be used as a coadjuvant treatment to accelerate orthodontic tooth movement (OTM). However, there are still uncertainty and discourse around the optimal PBM protocols, which hampers its optimal and consolidated clinical applicability. Given the differential expression and metabolic patterns exhibited in the tension and compression sides of orthodontically stressed teeth, it is plausible that different types of irradiation may be applied to each side of the teeth. In this sense, this study aimed to design and implement an optimization protocol to find the most appropriate PBM parameters to stimulate specific bone turnover processes. To this end, three levels of wavelength (655, 810 and 940 nm), two power densities (5 and 10 mW/cm2) and two regimens of single and multiple sessions within three consecutive days were tested. The biological response of osteoblasts and periodontal ligament (PDL) fibroblasts was addressed by monitoring the PBM's impact on the cellular metabolic activity, as well as on key bone remodeling mediators, including alkaline phosphatase (ALP), osteoprotegerin (OPG) and receptor activator of nuclear factor κ-B ligand (RANK-L), each day. The results suggest that daily irradiation of 655 nm delivered at 10 mW/cm2, as well as 810 and 940 nm light at 5 mW/cm2, lead to an increase in ALP and OPG, potentiating bone formation. In addition, irradiation of 810 nm at 5 mW/cm2 delivered for two consecutive days and suspended by the third day promotes a downregulation of OPG expression and a slight non-significant increase in RANK-L expression, being suitable to stimulate bone resorption. Future studies in animal models may clarify the impact of PBM on bone formation and resorption mediators for longer periods and address the possibility of testing different stimulation periodicities. The present in vitro study offers valuable insights into the effectiveness of specific PBM protocols to promote osteogenic and osteoclastogenesis responses and therefore its potential to stimulate bone formation on the tension side and bone resorption on the compression side of orthodontically stressed teeth.This research was supported by FCT (Fundação para a Ciência e Tecnologia) in the scope of the grants UI/BD/09375/2020 and UI/BD/150951/2021, and through the projects UIDB/04436/2020 and UIDP/04436/2020. Additional national funds were provided by FCT under the scope of the projects Stimcart (doi: 10.54499/PTDC/EME-EME/4520/2021), FunFibRAI (doi: 10.54499/PTDC/ EME-EME/4197/2021), and BrainStimMap (doi: 10.54499/PTDC/EME-EME/1681/2021), as well as through the contract 2020.00215.CEECIND (doi: 10.54499/2020.00215.CEECIND/CP1600/CT0009). Finally, funding was also given by CESPU—Cooperativa de Ensino Superior Politécnico e Universitário, in the scope of the project AlignAgen-GI2-CESPU-2022

LEISHMANIOSE VISCERAL CANINA: AVALIAÇÃO DE HEMOGRAMA E MIELOGRAMA

Visceral leishmaniasis (VL) is a chronic, multisystemic, and common disease that affects dogs and that can present changes in several laboratory tests, including blood count and myelogram. Thus, this work aimed to describe and evaluate changes in the blood count and myelogram of six dogs positive for leishmaniasis treated at the Veterinary Hospital Ivan Macedo Tabosa of the Federal University of Campina Grande. The diagnoses were confirmed by observing the amastigote forms of Leishmania sp in bone marrow aspirates. In the blood count, most animals presented anemia, thrombocytopenia, and leukocytosis with neutrophilia. Besides, two animals had leukopenia. In the myelogram, most animals presented granulocytic and megakaryocytic hyperplasia, in addition to erythroid hypoplasia. It is concluded that the performance of laboratory tests, such as blood count and myelogram, in animals suspected of VL is important for monitoring the patient's clinical condition and for selecting the therapeutic measures to be used, which can reflect positively on the prognosis.A leishmaniose visceral (LV) é uma enfermidade crônica, multissistêmica e comum, que afeta os cães e pode apresentar alterações em diversos exames laboratoriais, inclusive no hemograma e mielograma. Desse modo, o objetivo deste trabalho foi descrever e avaliar as alterações no hemograma e mielograma de seis cães positivos para leishmaniose atendidos no Hospital Universitário Ivan Macedo Tabosa da Universidade Federal de Campina Grande. Os diagnósticos foram confirmados através da observação das formas amastigotas de Leishmania sp em aspirados de medula óssea. No hemograma, a maior parte dos animais apresentou anemia, trombocitopenia e leucocitose com neutrofilia. Além disso, dois animais apresentaram leucopenia. No mielograma, a maioria dos animais apresentou hiperplasia granulocítica e megacariocítica, além de hipoplasia eritroide. Conclui-se que a realização de exames laboratoriais, como hemograma e mielograma, em animais suspeitos de LV é importante para o acompanhamento do quadro clínico do paciente e para a seleção de medidas terapêuticas a serem adotadas, o que pode refletir positivamente no prognóstico

ABORDAGEM CLÍNICA E LABORATORIAL DE UM CÃO COM HIPOPLASIA ERITRÓIDE E HIPERPLASIA GRANULÓCITICA ASSOCIADO À LEISHMANIOSE VISCERAL

Visceral leishmaniasis (VL) is a common disease that affects multiple systems and has a chronic evolution time. Among the laboratory characteristics that may occur, bone marrow changes may range from hypoplasia to both erythroid and granulocytic hyperplasia. Therefore, the present study aims to perform a clinical and laboratory analysis of the findings in a dog with erythroid hypoplasia and granulocytic hyperplasia associated with VL. A 7 - years-old male Irish Setter dog was attended at the Ivon Macêdo Tabosa Veterinary Hospital of the Federal University of Campina Grande (HVIMT / UFCG) presenting epistaxy, weight loss and hyporexia. Complete blood count, serum biochemistry analysis, urinalysis, amd a myelogram with hemoparasites were requested. The complete blood count showed normochromic normocytic anemia and a decrease in the number of platelets with platelet aggregates. Serum biochemistry revealed hypoalbuminemia and hyperproteinemia. Urinalysis showed no clinically relevant changes. Leishmaniasis amastigotes were observed in the myelogram along with erythroid hypoplasia and granulocytic hyperplasia. The animal was treated with the combination of milteforan, allopurinol and domperidone, however the tutor did not return for the patient's reassessment. In the light of the above, a clinical laboratory approach of a patient with VL is important for a better treatment and to improve the prognosis. Further studies should be performed to better understand the hematopathological responses to this disease.A leishmaniose visceral (LV) é uma enfermidade comum que acomete múltiplos sistemas e apresenta tempo de evolução crônico. Dentre as características laboratoriais que são observadas, os achados na medula óssea podem variar de hipoplasia a hiperplasia, tanto eritróide quanto granulocítica. Diante disso, o presente trabalho tem como objetivo realizar uma análise clínica e laboratorial dos achados em um cão com hipoplasia eritroide e hiperplasia granulocitica associada à LV. Um cão da raça Setter Irlandês, macho, com 7 anos de idade foi atendido no Hospital Veterinária Ivon Macêdo Tabosa da Universidade Federal de Campina Grande (HVIMT / UFCG) apresentando epistaxe, perda de peso e hiporexia. Foi solicitado hemograma completo, análise de bioquímica sérica, urinálisen e mielograma com pesquisa de hemoparasitas. No hemograma foi evidenciado anemia normocítica normocrômica e diminuição da quantidade de plaquetas com presença de agregados plaquetários. A bioquímica sérica revelou hipoalbuminemia e hiperproteinemia. Na urinalise não foi evidenciada alterações com relevância clínica. Foi observada amastigotas de Leishmaniasp no mielograma, e hipoplasia eritróide e hiperplasia granulócitica. O animal foi tratado com associação de milteforan, alopurinol e domperidona, contudo o tutor não retornou para reavaliação do paciente. Diante do exposto, uma abordagem clínica laboratorial de um paciente com LV é importante para um tratamento mais adequado e melhorar o prognóstico. Mais estudos devem ser realizados para a melhor compreensão das respostas hematopatológicas frente a essa enfermidade

ANÁLISE CLÍNICO-LABORATORIAL DE UM FELINO COM ESPOROTRICOSE CUTÂNEA

Sporotrichosis is a subcutaneous pyogranulomatous mycosis caused by a fungus that affects a wide variety of animals and humans. Its diagnosis is based on anamnesis, physical examination, and complementary exams such as cytopathology of the secretion, histopathology of the injured skin and the macro and microscopic morphological study of fungal culture. This study aims to describe the laboratory findings of a feline with sporotrichosis, associating them with the clinical form of this disease. A domestic cat was treated at the University Veterinarian Hospital Prof. Dr. Ivon Macêdo Tabosa in the city of Patos, State of Paraíba, in july 2019. The patient had ear wounds with secretion, swelling with reddish color, circular areas of alopecia and flaking in the left pelvic limb. Blood count, serum biochemistry, cytology and mycological culture exams were requested. There were no changes in the erythrogram and platelet chart. In the leukogram, it was observed leukocytosis with a left regenerative deviation. The cytopathological examination of the lesion showed structures compatible with yeasts of Sporothrix spp.  At the bottom of the slide and inside the leukocytes. However, it is suggested that other differential methods of diagnosis be indicated in order not to exclude the possibility of the disease.A esporotricose é uma micose subcutânea piogranulomatosa causada por um fungo saprófito que acomete grande variedade de animais e também os humanos. O diagnóstico baseia-se na anamnese, exame físico e exames complementares tais como citopatológico da secreção, histopatológico da pele acometida e no estudo morfológico macro e microscópico da cultura fúngica. O presente estudo tem como objetivo descrever os achados laboratoriais de um felino com esporotricose, associando-os com a forma clínica desta enfermidade. Um gato doméstico foi atendido no Hospital Veterinário Universitário Prof. Dr. Ivon Macêdo Tabosa no município de Patos, no estado da Paraíba, em julho de 2019. O paciente apresentava feridas na orelha com presença de secreção, aumento de volume com coloração avermelhada, áreas circulares de alopecia e descamação no membro pélvico esquerdo. Foi solicitado hemograma, bioquímica sérica, citologia e cultura micológica. Não houve alterações no eritrograma e plaquetograma. No leucograma, observou-se leucocitose com desvio a esquerda regenerativo. O exame citopatológico da lesão apresentou estruturas compatíveis com leveduras de Sporothrix spp. no fundo de lâmina e no interior dos leucócitos. No entanto, é sugerido que outros métodos diferenciais de diagnósticos sejam indicados para não excluir a possibilidade da doença

AVALIAÇÃO CLÍNICA E LABORATORIAL DA DERMATITE ATÓPICA CANINA

The canine atopic dermatitis (CAD) is an inflammatory skin disease, chronic itchy that affects genetically predisposed individuals, being commonly associated with production of IgE antibodies. The aim of this study was to describe a case of CAD, evidencing its clinical signs, diagnosis and treatment. A Wood lamp, skin deep scraping, skin imprint, fungal and bacterial culture, ear cytology, serological examination for canine visceral leishmaniasis (LVC) and allergen sensitivity test were performed. The animal presented a series of disseminated dermatological lesions accompanied by intense pruritus, where it is possible to observe presences of secondary infections by bacteria and yeasts fungi. Thus, it was decided to topical treatment with shampoo chlorhexidine base 2% associated with miconazole 2.5% and use moisturizer. For bilateral otitis, otologic solution of cyclopirox olamine 1% and glycyrrhizic acid 0.5% was prescribed. After negative response to the initial treatment, the oral use of prednisolone associated with hydroxyzine and soon after cyclosporine was introduced, and clinical control was performed. Although several therapeutic alternatives are available, cure is still not possible, and lesion control is the best treatment approach.A dermatite atópica canina (DAC) é uma dermatopatia inflamatória, crônica e pruriginosa que afeta indivíduos geneticamente predispostos, sendo comumente associada à produção de anticorpos do tipo IgE. O presente relato objetivou descrever um caso de DAC, evidenciando seus sinais clínicos, diagnóstico e tratamento. Foram realizados teste com lâmpada de Wood, raspado profundo de pele, imprint cutâneo, cultura fúngica e bacteriana, citologia de ouvido, exame sorológico para leishmaniose visceral canina (LVC) e teste de sensibilidade a alérgenos. O paciente apresentava uma série de lesões dermatológicos disseminadas acompanhadas de prurido intenso, onde pode-se observar presenças de infecções secundárias por bactérias e leveduras fúngicas. Dessa forma, optou-se por tratamento tópico com shampoo a base de clorexidina 2% associado a miconazol 2,5% e uso de creme hidratante. Para otite bilateral, prescreveu-se solução otológica de ciclopirox olamina 1% e ácido glicirrízico 0,5%. Após resposta negativa ao tratamento inicial, introduziu-se o uso oral de prednisolona associado à hidroxizina e logo depois a ciclosporina, ocorrendo um controle do quadro. Embora várias alternativas terapêuticas estejam disponíveis, a cura ainda não é possível, sendo o controle do quadro lesional a melhor abordagem de tratamento

Análise termodinâmica da produção de 1,3- butadieno a partir do etanol aplicando o método da minimização da energia livre de GIBBS / Thermodynamic analysis of 1,3- butadiene production from ethanol applying the GIBBS free energy minimization method

Conhecer a conversão no equilíbrio de uma reação fornece uma meta para balizar otimizações em qualquer processo. A conversão depende de fatores como temperatura, pressão e composição dos reagentes. Diante disso, foi desenvolvido um algoritmo computacional que realiza a análise termodinâmica de reações, aplicando o método da minimização da energia livre de Gibbs. A reação analisada foi a produção de 1,3-butadieno a partir do etanol, composto importante na produção de borrachas sintéticas. O 1,3-butadieno é produzido em duas etapas, passando pela produção de acetaldeído. Foi encontrada uma razão ótima de C2H6O:C2H4O de 3:1, a partir do qual ocorre a conversão final para 1,3-butadieno. Estudou-se a influência da temperatura na conversão, com valores de 100 a 900ºC, à 1 bar. Conclui-se que a melhor faixa de temperatura é entre 250 e 350 ºC, para atingir uma razão de C2H6O:C2H4O. de 3:1 objetivando otimizar a conversão de 1,3-butadieno, encontrando um valor de 28%.

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

Differential Regional Immune Response in Chagas Disease

Following infection, lymphocytes expand exponentially and differentiate into effector cells to control infection and coordinate the multiple effector arms of the immune response. Soon after this expansion, the majority of antigen-specific lymphocytes die, thus keeping homeostasis, and a small pool of memory cells develops, providing long-term immunity to subsequent reinfection. The extent of infection and rate of pathogen clearance are thought to determine both the magnitude of cell expansion and the homeostatic contraction to a stable number of memory cells. This straight correlation between the kinetics of T cell response and the dynamics of lymphoid tissue cell numbers is a constant feature in acute infections yielded by pathogens that are cleared during the course of response. However, the regional dynamics of the immune response mounted against pathogens that are able to establish a persistent infection remain poorly understood. Herein we discuss the differential lymphocyte dynamics in distinct central and peripheral lymphoid organs following acute infection by Trypanosoma cruzi, the causative agent of Chagas disease. While the thymus and mesenteric lymph nodes undergo a severe atrophy with massive lymphocyte depletion, the spleen and subcutaneous lymph nodes expand due to T and B cell activation/proliferation. These events are regulated by cytokines, as well as parasite-derived moieties. In this regard, identifying the molecular mechanisms underlying regional lymphocyte dynamics secondary to T. cruzi infection may hopefully contribute to the design of novel immune intervention strategies to control pathology in this infection