Scrub Typhus Incidence Modeling with Meteorological Factors in South Korea

Since its recurrence in 1986, scrub typhus has been occurring annually and it is considered as one of the most prevalent diseases in Korea. Scrub typhus is a 3rd grade nationally notifiable disease that has greatly increased in Korea since 2000. The objective of this study is to construct a disease incidence model for prediction and quantification of the incidences of scrub typhus. Using data from 2001 to 2010, the incidence Artificial Neural Network (ANN) model, which considers the time-lag between scrub typhus and minimum temperature, precipitation and average wind speed based on the Granger causality and spectral analysis, is constructed and tested for 2011 to 2012. Results show reliable simulation of scrub typhus incidences with selected predictors, and indicate that the seasonality in meteorological data should be considered

Comparisons of the Effects of Stent Eccentricity on the Neointimal Hyperplasia between Sirolimus-Eluting Stent versus Paclitaxel-Eluting Stent

PURPOSE: Previous studies suggested that asymmetric stent expansion did not affect suppression of neointimal hyperplasia (NIH) after sirolimus-eluting stents (SES) implantation. The aim of this study was to evaluate the effects of stent eccentricity (SE) on NIH between SES versus paclitaxel-eluting stents (PES) using an intravascular ultrasound (IVUS) analysis from the randomized trial. MATERIALS AND METHODS: Serial IVUS data were obtained from Post-stent Optimal Expansion (POET) trial, allocated randomly to SES or PES. Three different SE (minimum stent diameter divided by maximum stent diameter) were evaluated; SE at the lesion site with maximal %NIH area (SE-NIH), SE at the minimal stent CSA [SE-minimal stent area (SE-MSA)], and averaged SE through the entire stent (SE-mean). We classified each drug-eluting stents (DES) into the concentric (≥ mean SE) and eccentric groups (< mean SE) based on the mean value of SE. RESULTS: Among 301 enrolled patients, 233 patients [SES (n = 108), PES (n = 125)] underwent a follow-up IVUS. There was no significant correlation between %NIH area and SE-NIH (r = - 0.083, p = 0.391) or SE-MSA (r = - 0.109, p = 0.259) of SES. However, SE-NIH of PES showed a weak but significant correlation with %NIH area (r = 0.269, p < 0.01). As to the associations between SEmean and NIH volume index, SES revealed no significant correlation (r = - 0.001, p = 0.990), but PES showed a weak but significant correlation (r = 0.320, p < 0.01). However, there was no difference in the restenosis rate between the eccentric versus concentric groups of both DES. CONCLUSION: This study suggests that lower SE of both SES and PES, which means asymmetric stent expansion, may not be associated with increased NIH.ope

Reinvestigation of aminoacyl-TRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex

10.1371/journal.pone.0081734PLoS ONE812-POLN

Observation of tW production in the single-lepton channel in pp collisions at root s=13 TeV

A measurement of the cross section of the associated production of a single top quark and a W boson in final states with a muon or electron and jets in proton-proton collisions at root s = 13 TeV is presented. The data correspond to an integrated luminosity of 36 fb(-1) collected with the CMS detector at the CERN LHC in 2016. A boosted decision tree is used to separate the tW signal from the dominant t (t) over bar background, whilst the subleading W+jets and multijet backgrounds are constrained using data-based estimates. This result is the first observation of the tW process in final states containing a muon or electron and jets, with a significance exceeding 5 standard deviations. The cross section is determined to be 89 +/- 4 (stat) +/- 12 (syst) pb, consistent with the standard model.Peer reviewe

Technical Trends Related to Intermodal Automated Freight Transport Systems (AFTS) *

In recent years, advanced countries including the US, Germany, the Netherlands and Japan have been actively developing automated intermodal freight transport system technology aimed at reducing greenhouse gas and fine dust, minimizing infrastructure costs and logistics costs, and mitigating traffic congestion have. The purpose of this study is to provide direction for the development of automated intermodal freight transport system by analyzing trends of related technology. Keywords: Automated Freight Transport Systems(AFTS), Freight Transport, Efficient Transport, Port and Inland Hub, Technology Tren

Characteristics Analysis of Freight Mode Choice Model According to the Introduction of a New Freight Transport System

The purpose of this study is to identify the characteristics of freight mode choices made by shippers and carriers with the introduction of a new freight transport system. We set an area in which actual freight transport takes place as the analysis scope and performed a survey of the shippers and carriers that transport containers to identify their stated preference (SP) regarding the new freight mode. The SP survey was carried out through an experimental design and this study considered the three factors of transport time, transport cost, and service level. This study compared and analyzed the models by distance using an individual behavior model. The results of estimating the model showed that the explanatory power of the model classified by distance and the individual parameters have statistical significance. The hit ratio was also high, which confirms that the model was estimated properly. In addition, the range of elasticity and the value of travel time analyzed using the model were evaluated to be appropriate compared to previous studies. The findings of the elasticity analysis show that strategies for reducing the transport cost are effective to increase the demand for the new transport mode. The value of travel time of freight transport was found to be higher than the current value generally applied in Korea. Considering that the value of travel time currently used is based on road freight transport, further research is required to apply a new value of travel time that reflects the characteristics of the new transport mode in the future