261 research outputs found

    WATER AND POWER IN ARCHITECTURE: Charleston SC

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    Charleston has not always been the peninsula it is today. In fact over time it has increased in size. It took a tremendous leap forward between 1670 and 1802. The city has been gaining ground through the use of landfill techniques. This project explores the relationship of ground and power. Through examining Charleston’s role in the slave trade it is revealed that expansion of the city is influenced by the political and economic values of the time and vice versa. Under the Supervision of Professor John Craig Bab

    Outpatient Physical Therapy Management Of A Patient Three Months Following Left Shoulder Arthroscopic Repair Of A Type-II SLAP Lesion: A Case Report

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    Background: Research demonstrates a drastic increase in the prevalence of type-II superior labral anterior-posterior (SLAP) lesion repairs, and its surgical correction has become the favored method of treatment, because of its ability to effectively improve quality of life (QOL). A type-II SLAP lesion consists of fraying and degenerative changes to the superior labrum, in an anterior to posterior direction, with the biceps tendon detached from the glenoid. Purpose: Document the examination, evaluation, and plan of care (POC) concerning a patient that was referred to physical therapy (PT) three months following the surgical correction of a type-II SLAP lesion.https://dune.une.edu/pt_studcrposter/1004/thumbnail.jp

    Sustainable by design: an investigation into ecologically friendly typography

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    This research investigates the effects that font choice, typographic design, and page layout have on the conservation of ink and paper. This is one part of a broader concern with the environmental sustainability of digital printing. The particular focus of this report is on thesis guidelines for graduate students in the School of Print Media at RIT. The preparation and printing of theses is a salient area of paper and ink consumption at an institution of higher education and research. Established, well-defined thesis guidelines permit precise comparisons of the effects of different typographic factors on materials consumption. Three different aspects were investigated in the preparation and publication of graduate theses in order to determine the amount of reduction possible in paper and ink consumption. A high measurable potential for waste reduction was found. The first aspect is the modification of typographic parameters—within current established guidelines—to reduce paper use. Following this, changes to the typographic components of the thesis guidelines were recommended to increase paper savings further. The second aspect is the selection of alternative, ink-economical typefaces and fonts to reduce ink consumption. The third aspect is modification of the letter forms of fonts to reduce ink consumption even further while maintaining apparent readability. It was found that measurable, material savings can be derived from changes to all these aspects of thesis guidelines, and it is expected that similar savings may be derived from the applications of similar methods to more general institutional printing

    Cancer Survivorship Care: An Emphasis On Rehabilitation Needs In Maine

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    The first section of this report addresses the evidence of causation concerning impairments developed as a result of a cancer diagnosis and cancer treatment. The second section investigates the evidence regarding rehabilitation and physical activity as an effective intervention in the prevention and treatment of impairments from cancer diagnosis and cancer treatment. The third section discusses the underlying behavioral change theory for incorporation of our Cancer Survivorship Rehabilitation Algorithm (Appendix 1), which details our proposed use of rehabilitation and wellness services in the continuum of cancer care and includes an outline for a survivorship care plan. This section also discusses the efficacy of delivery of our product to healthcare professionals. The fourth section outlines our proposed methods of evaluation for the utilization of our algorithm

    Rare Occurrence of a Poorly Differentiated Neuroendocrine Tumor of the Bladder

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    Neuroendocrine tumors rarely occur in the urinary bladder. They can be carcinomatous, subdivided into small cell and large cell pathology. Small cell carcinoma of the bladder is a rarity that may present at an advanced pathologic stage. No treatment regimens have been standardized for local or metastatic disease. Review of the recent literature shows equivalent survival data for localized disease treated with chemoradiotherapy combined with either bladder sparing surgery or radical cystectomy. Patients with significant comorbidities are an additional challenge. We report a case of poorly differentiated neuroendocrine tumor of the bladder, which could not be classified as small or large cell carcinoma, complicated by significant comorbidities. After management with transurethral resection of the tumor, adjuvant chemotherapy, and radiation, the patient is alive and asymptomatic nearly 1 year after initial TURBT with no evidence of disease recurrence

    FishFace: interactive atlas of zebrafish craniofacial development at cellular resolution

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    Background: The vertebrate craniofacial skeleton may exhibit anatomical complexity and diversity, but its genesis and evolution can be understood through careful dissection of developmental programs at cellular resolution. Resources are lacking that include introductory overviews of skeletal anatomy coupled with descriptions of craniofacial development at cellular resolution. In addition to providing analytical guidelines for other studies, such an atlas would suggest cellular mechanisms underlying development. Description We present the Fish Face Atlas, an online, 3D-interactive atlas of craniofacial development in the zebrafish Danio rerio. Alizarin red-stained skulls scanned by fluorescent optical projection tomography and segmented into individual elements provide a resource for understanding the 3D structure of the zebrafish craniofacial skeleton. These data provide the user an anatomical entry point to confocal images of Alizarin red-stained zebrafish with transgenically-labelled pharyngeal arch ectomesenchyme, chondrocytes, and osteoblasts, which illustrate the appearance, morphogenesis, and growth of the mandibular and hyoid cartilages and bones, as viewed in live, anesthetized zebrafish during embryonic and larval development. Confocal image stacks at high magnification during the same stages provide cellular detail and suggest developmental and evolutionary hypotheses. Conclusion: The FishFace Atlas is a novel learning tool for understanding craniofacial skeletal development, and can serve as a reference for a variety of studies, including comparative and mutational analyses

    Quantifying impacts of the COVID-19 pandemic through life-expectancy losses: a population-level study of 29 countries.

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    BACKGROUND: Variations in the age patterns and magnitudes of excess deaths, as well as differences in population sizes and age structures, make cross-national comparisons of the cumulative mortality impacts of the COVID-19 pandemic challenging. Life expectancy is a widely used indicator that provides a clear and cross-nationally comparable picture of the population-level impacts of the pandemic on mortality. METHODS: Life tables by sex were calculated for 29 countries, including most European countries, Chile and the USA, for 2015-2020. Life expectancy at birth and at age 60 years for 2020 were contextualized against recent trends between 2015 and 2019. Using decomposition techniques, we examined which specific age groups contributed to reductions in life expectancy in 2020 and to what extent reductions were attributable to official COVID-19 deaths. RESULTS: Life expectancy at birth declined from 2019 to 2020 in 27 out of 29 countries. Males in the USA and Lithuania experienced the largest losses in life expectancy at birth during 2020 (2.2 and 1.7 years, respectively), but reductions of more than an entire year were documented in 11 countries for males and 8 among females. Reductions were mostly attributable to increased mortality above age 60 years and to official COVID-19 deaths. CONCLUSIONS: The COVID-19 pandemic triggered significant mortality increases in 2020 of a magnitude not witnessed since World War II in Western Europe or the breakup of the Soviet Union in Eastern Europe. Females from 15 countries and males from 10 ended up with lower life expectancy at birth in 2020 than in 2015

    Abundance and Distribution of Enteric Bacteria and Viruses in Coastal and Estuarine Sediments—a Review

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    The long term survival of fecal indicator organisms (FIOs) and human pathogenic microorganisms in sediments is important from a water quality, human health and ecological perspective. Typically, both bacteria and viruses strongly associate with particulate matter present in freshwater, estuarine and marine environments. This association tends to be stronger in finer textured sediments and is strongly influenced by the type and quantity of clay minerals and organic matter present. Binding to particle surfaces promotes the persistence of bacteria in the environment by offering physical and chemical protection from biotic and abiotic stresses. How bacterial and viral viability and pathogenicity is influenced by surface attachment requires further study. Typically, long-term association with surfaces including sediments induces bacteria to enter a viable-but-non-culturable (VBNC) state. Inherent methodological challenges of quantifying VBNC bacteria may lead to the frequent under-reporting of their abundance in sediments. The implications of this in a quantitative risk assessment context remain unclear. Similarly, sediments can harbor significant amounts of enteric viruses, however, the factors regulating their persistence remains poorly understood. Quantification of viruses in sediment remains problematic due to our poor ability to recover intact viral particles from sediment surfaces (typically <10%), our inability to distinguish between infective and damaged (non-infective) viral particles, aggregation of viral particles, and inhibition during qPCR. This suggests that the true viral titre in sediments may be being vastly underestimated. In turn, this is limiting our ability to understand the fate and transport of viruses in sediments. Model systems (e.g., human cell culture) are also lacking for some key viruses, preventing our ability to evaluate the infectivity of viruses recovered from sediments (e.g., norovirus). The release of particle-bound bacteria and viruses into the water column during sediment resuspension also represents a risk to water quality. In conclusion, our poor process level understanding of viral/bacterial-sediment interactions combined with methodological challenges is limiting the accurate source apportionment and quantitative microbial risk assessment for pathogenic organisms associated with sediments in aquatic environments
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