44 research outputs found

    Anti-fascist Art Theory: A Roundtable Discussion

    Get PDF
    Taking the form of a conversation among three art theorists whose work focuses on contemporary art, culture and emancipatory politics on the left, this roundtable article begins from the question: what concepts and ideas can be drawn into an anti-fascist art theory today? The discussion opens by considering the ambivalence towards speaking about fascism in current debates beyond art and the complex positioning of art between (or rather, across) the status quo and its subversion; proceeds by examining the current technological apparatus as regards the mediation of subjectivity; looks at the articulation of sexuality and whiteness; and concludes by proposing that anti-fascism as a complex political position that crosses an art field sustained also by an attention economy must address the field’s structural procedures of exclusion while also maintain its focus on the specificity of fascist politics

    THE VARIABILITY OF VERTICAL GROUND REACTION FORCES DURING UNLOADED AND LOADED DROP JUMPING

    Get PDF
    The increase of the resistance of the movement - on the basis of the dynamic fundamental law F.t = m.v (Force Impulse = Change of the Kinematic Impulse) - can be achieved either by increasing the drop velocity v (initial height of the drop jump) or by increasing the body mass m of the athlete (adding a weighted vest). The purpose of this study was to investigate the behavior of the forcetime parameters of the force impulse by varying the kinematic impulse, using unloaded and loaded drop jumping. METHOD Ten top track & field and diving athletes (6 male and 4 female) participated in this study, 17-24 years old. The subjects were instructed to perform three unloaded drop jumps from heights (drop velocities) of 0.30 m (2.43 d s ) , 0.45m (2.97 d s ) , 0.55m (3.28 d s ) and two loaded drop jumps from a standard height of 0.30m (2.434s) where the additional load was defined based on the Kinematic impulses that arise from the unloaded drop jumps the height of 0.45m and 0.55111 respectively. A Kistler fore platform was used to record the force-time curves of the jumps. RESULTS AND DISCUSSION The calculated values of the average vertical jumped distances for the unloaded conditions (drop height 0.45m,0.55m), as it was expected, were found to be 20% and 31% higher in comparison to the loaded drop jumps respectively. The results of the analysis of the variability in the force-time parameters have shown no significant differences (p>.05, student's t-test at .05 level) for the total average force (acceleration force and loaded force) between unloaded and loaded jumps while for the acceleration force significant differences (

    Emotional, behavioural problems and cigarette smoking in adolescence: findings of a Greek cross-sectional study

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>Although several studies have reported findings concerning the association between smoking and emotional/behavioural problems, little research has investigated this association after controlling for confounding factors which have been found to be significantly correlated with both cigarette smoking and emotional/behavioural problems and may have a strong effect on the relationship between adolescents' mental health and smoking. The present study attempted to assess the association between adolescents' smoking status and their emotional/behavioural problems after controlling for a number of possible confounders (i.e. age, gender, parental smoking status, exposure to family smoking, family socioeconomic status, adolescents' leisure time) in a Greek nation-wide school-based sample.</p> <p>Methods</p> <p>Participants completed a questionnaire which retrieved information about age, gender, family socioeconomic status, smoking status, parental smoking, adolescents' leisure time and emotional/behavioural problems. Data were modelled using multiple logistic regression analysis with adolescents' smoking status as the dependent variable.</p> <p>Results</p> <p>A total of 1194 (i.e. 63% response rate) of self-reported questionnaires (40.1% boys, 59.9% girls; 12-18 years old) were returned. Data from 1030 participants with full data were analyzed. Cigarette smoking was strongly associated with higher levels of emotional/behavioural problems (p < 0.001) and the association was not moderated (OR = 1.13, 95% CI: 1.08-1.18) after controlling for the effects of other covariates. Emotional symptoms, conduct problems and hyperactivity/inattention were all significantly associated with adolescents' current smoking.</p> <p>Conclusions</p> <p>This study supports the association between smoking and emotional/behavioural problems among adolescents. Addressing adolescents' needs regarding their emotional/behavioural health could be helpful in the development of effective anti-smoking strategies in school environment and elsewhere.</p

    Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection: A case control study

    Get PDF
    Introduction: The use of anti-retroviral therapy (ART) has dramatically reduced HIV-1 associated morbidity and mortality. However, HIV-1 infected individuals have increased rates of morbidity and mortality compared to the non-HIV-1 infected population and this appears to be related to end-organ diseases collectively referred to as Serious Non-AIDS Events (SNAEs). Circulating miRNAs are reported as promising biomarkers for a number of human disease conditions including those that constitute SNAEs. Our study sought to investigate the potential of selected miRNAs in predicting mortality in HIV-1 infected ART treated individuals. Materials and Methods: A set of miRNAs was chosen based on published associations with human disease conditions that constitute SNAEs. This case: control study compared 126 cases (individuals who died whilst on therapy), and 247 matched controls (individuals who remained alive). Cases and controls were ART treated participants of two pivotal HIV-1 trials. The relative abundance of each miRNA in serum was measured, by RTqPCR. Associations with mortality (all-cause, cardiovascular and malignancy) were assessed by logistic regression analysis. Correlations between miRNAs and CD4+ T cell count, hs-CRP, IL-6 and D-dimer were also assessed. Results: None of the selected miRNAs was associated with all-cause, cardiovascular or malignancy mortality. The levels of three miRNAs (miRs -21, -122 and -200a) correlated with IL-6 while miR-21 also correlated with D-dimer. Additionally, the abundance of miRs -31, -150 and -223, correlated with baseline CD4+ T cell count while the same three miRNAs plus miR- 145 correlated with nadir CD4+ T cell count. Discussion: No associations with mortality were found with any circulating miRNA studied. These results cast doubt onto the effectiveness of circulating miRNA as early predictors of mortality or the major underlying diseases that contribute to mortality in participants treated for HIV-1 infection

    Development and Validation of a Risk Score for Chronic Kidney Disease in HIV Infection Using Prospective Cohort Data from the D:A:D Study

    Get PDF
    Ristola M. on työryhmien DAD Study Grp ; Royal Free Hosp Clin Cohort ; INSIGHT Study Grp ; SMART Study Grp ; ESPRIT Study Grp jäsen.Background Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotoxic antiretrovirals to a treatment regimen and would identify those at greatest risk of CKD. The aims of this study were to develop a simple, externally validated, and widely applicable long-term risk score model for CKD in HIV-positive individuals that can guide decision making in clinical practice. Methods and Findings A total of 17,954 HIV-positive individuals from the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study with >= 3 estimated glomerular filtration rate (eGFR) values after 1 January 2004 were included. Baseline was defined as the first eGFR > 60 ml/min/1.73 m2 after 1 January 2004; individuals with exposure to tenofovir, atazanavir, atazanavir/ritonavir, lopinavir/ritonavir, other boosted protease inhibitors before baseline were excluded. CKD was defined as confirmed (>3 mo apart) eGFR In the D:A:D study, 641 individuals developed CKD during 103,185 person-years of follow-up (PYFU; incidence 6.2/1,000 PYFU, 95% CI 5.7-6.7; median follow-up 6.1 y, range 0.3-9.1 y). Older age, intravenous drug use, hepatitis C coinfection, lower baseline eGFR, female gender, lower CD4 count nadir, hypertension, diabetes, and cardiovascular disease (CVD) predicted CKD. The adjusted incidence rate ratios of these nine categorical variables were scaled and summed to create the risk score. The median risk score at baseline was -2 (interquartile range -4 to 2). There was a 1: 393 chance of developing CKD in the next 5 y in the low risk group (risk score = 5, 505 events), respectively. Number needed to harm (NNTH) at 5 y when starting unboosted atazanavir or lopinavir/ritonavir among those with a low risk score was 1,702 (95% CI 1,166-3,367); NNTH was 202 (95% CI 159-278) and 21 (95% CI 19-23), respectively, for those with a medium and high risk score. NNTH was 739 (95% CI 506-1462), 88 (95% CI 69-121), and 9 (95% CI 8-10) for those with a low, medium, and high risk score, respectively, starting tenofovir, atazanavir/ritonavir, or another boosted protease inhibitor. The Royal Free Hospital Clinic Cohort included 2,548 individuals, of whom 94 individuals developed CKD (3.7%) during 18,376 PYFU (median follow-up 7.4 y, range 0.3-12.7 y). Of 2,013 individuals included from the SMART/ESPRIT control arms, 32 individuals developed CKD (1.6%) during 8,452 PYFU (median follow-up 4.1 y, range 0.6-8.1 y). External validation showed that the risk score predicted well in these cohorts. Limitations of this study included limited data on race and no information on proteinuria. Conclusions Both traditional and HIV-related risk factors were predictive of CKD. These factors were used to develop a risk score for CKD in HIV infection, externally validated, that has direct clinical relevance for patients and clinicians to weigh the benefits of certain antiretrovirals against the risk of CKD and to identify those at greatest risk of CKD.Peer reviewe

    Gothic Public Art and the Failures of Democracy: Reflections on 'House', Interpretation and the 'Political Unconscious'

    No full text
    This book chapter considers Rachel Whiteread's most famous public sculpture to date, House, surviving as a 'document'. Over ten years after House's 'disappearance', the argument presented here attempts to read through the controversy and the debates generated by this landmark piece and place its memory within a wider realm of ongoing, intersecting debates in contemporary art and political theory. These range from the contested definition of 'public art', the status of artwork as memory (House was planned to stand for three months) and the current meaning of democracy. Drawing on literature, geography and political theory, the author primarily deploys Fredric Jameson's concept of the 'political unconscious' to review the meaning and memory of this artwork as truly 'public'

    Femininity and utopia in women's film and video: towards a critical investigation

    No full text
    Based upon a major international conference organised by Humboldt University in Berlin, the volume (in German and English) brings together commissioned chapters based upon select conference papers (first submitted anonymously). Focusing on the contemporary theory of video, film, photography and painting, the volume aims to represent new directions in research form all over Europe
    corecore