156 research outputs found

    Volume Changes Of Alaska Glaciers: Contributions To Rising Sea Level And Links To Changing Climate

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    Thesis (Ph.D.) University of Alaska Fairbanks, 2006We have used airborne altimetry to measure surface elevations along the central flowline of 86 glaciers in Alaska, Yukon Territory and northwestern British Columbia (northwestern North America). Comparison of these elevations with contours on maps derived from 1950s to 1970s aerial photography yields elevation and volume changes over a 30 to 45 year period. Approximately one-third of glaciers have been re-profiled 3 to 5 years after the earlier profile, providing a measure of short-timescale elevation and volume changes for comparison with the earlier period. We have used these measurements to estimate the total contribution of glaciers in northwestern North America to rising sea level, and to quantify the magnitude of climate changes in these regions. We found that glaciers in northwestern North America have contributed to about 10% of the rate of global sea level rise during the last half-century and that the rate of mass loss has approximately doubled during the past decade. During this time, summer and winter air temperatures at low elevation climate stations increased by 0.2+/-0.1 and 0.4+/-0.2�C (decade)-1 respectively. There was also a weak trend of increasing precipitation and an overall lengthening of the summer melt season. We modeled regional changes in glacier mass balance with climate station data and were able to reproduce altimetry measurements to within reported errors. We conclude that summer temperature increases have been the main driver of the increased rates of glacier mass loss, but winter warming might also be affecting the glaciers through enhanced melt at low elevations and a change in precipitation from snow to rain, especially in maritime regions. Uncertainties in our calculations are large, owing to the inaccuracies of the maps used to provide baseline elevations, the sparsity of accurate climate data, and the complex and dynamic nature of glaciers in these regions. Tidewater, surging, and lake-terminating glaciers have dynamical cycles that are not linked in a simple way to climate variability. We found that regional volume losses can depend on one or several large and dynamic glaciers. These glaciers should be treated separately when extrapolating altimetry data to an entire region

    Dust processing in photodissociation regions - Mid-IR emission modelling

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    Mid-infrared spectroscopy of dense illuminated ridges (or photodissociation regions, PDRs) suggests dust evolution. Such evolution must be reflected in the gas physical properties through processes like photo-electric heating or H_2 formation. With Spitzer Infrared Spectrograph (IRS) and ISOCAM data, we study the mid-IR emission of closeby, well known PDRs. Focusing on the band and continuum dust emissions, we follow their relative contributions and analyze their variations in terms of abundance of dust populations. In order to disentangle dust evolution and excitation effects, we use a dust emission model that we couple to radiative transfer. Our dust model reproduces extinction and emission of the standard interstellar medium that we represent with diffuse high galactic latitude clouds called Cirrus. We take the properties of dust in Cirrus as a reference to which we compare the dust emission from more excited regions, namely the Horsehead and the reflection nebula NGC 2023 North. We show that in both regions, radiative transfer effects cannot account for the observed spectral variations. We interpret these variations in term of changes of the relative abundance between polycyclic aromatic hydrocarbons (PAHs, mid-IR band carriers) and very small grains (VSGs, mid-IR continuum carriers). We conclude that the PAH/VSG abundance ratio is 2.4 times smaller at the peak emission of the Horsehead nebula than in the Cirrus case. For NGC2023 North where spectral evolution is observed across the northern PDR, we conclude that this ratio is ~5 times lower in the dense, cold zones of the PDR than in its diffuse illuminated part where dust properties seem to be the same as in Cirrus. We conclude that dust in PDRs seems to evolve from "dense" to "diffuse" properties at the small spatial scale of the dense illuminated ridge.Comment: 11 pages, 11 figures, accepted for publication in A&

    Subjects with Knee Osteoarthritis Exhibit Widespread Hyperalgesia to Pressure and Cold

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    Hyperalgesia to mechanical and thermal stimuli are characteristics of a range of disorders such as tennis elbow, whiplash and fibromyalgia. This study evaluated the presence of local and widespread mechanical and thermal hyperalgesia in individuals with knee osteoarthritis, compared to healthy control subjects. Twenty-three subjects with knee osteoarthritis and 23 healthy controls, matched for age, gender and body mass index, were recruited for the study. Volunteers with any additional chronic pain conditions were excluded. Pain thresholds to pressure, cold and heat were tested at the knee, ipsilateral heel and ipsilateral elbow, in randomized order, using standardised methodology. Significant between-groups differences for pressure pain and cold pain thresholds were found with osteoarthritic subjects demonstrating significantly increased sensitivity to both pressure (p = .018) and cold (p = .003) stimuli, compared with controls. A similar pattern of results extended to the pain-free ipsilateral ankle and elbow indicating widespread pressure and cold hyperalgesia. No significant differences were found between groups for heat pain threshold, although correlations showed that subjects with greater sensitivity to pressure pain were also likely to be more sensitive to both cold pain and heat pain. This study found widespread elevated pain thresholds in subjects with painful knee osteoarthritis, suggesting that altered nociceptive system processing may play a role in ongoing arthritic pain for some patients

    Successful and unsuccessful cannabis quitters: Comparing group characteristics and quitting strategies

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    <p>Abstract</p> <p>Background</p> <p>In order to improve treatments for cannabis use disorder, a better understanding of factors associated with successful quitting is required.</p> <p>Method</p> <p>This study examined differences between successful (<it>n </it>= 87) and unsuccessful (<it>n </it>= 78) cannabis quitters. Participants completed a questionnaire addressing demographic, mental health, and cannabis-related variables, as well as quitting strategies during their most recent quit attempt.</p> <p>Results</p> <p>Eighteen strategies derived from cognitive behavioral therapy were entered into a principal components analysis. The analysis yielded four components, representing (1) Stimulus Removal, (2) Motivation Enhancement, (3) (lack of) Distraction, and (4) (lack of) Coping. Between groups comparisons showed that unsuccessful quitters scored significantly higher on Motivation Enhancement and (lack of) Coping. This may indicate that unsuccessful quitters focus on the desire to quit, but do not sufficiently plan strategies for coping. Unsuccessful quitters also had significantly more symptoms of depression and stress; less education; lower exposure to formal treatment; higher day-to-day exposure to other cannabis users; and higher cannabis dependence scores.</p> <p>Conclusions</p> <p>The findings suggest that coping, environmental modification, and co-morbid mental health problems may be important factors to emphasize in treatments for cannabis use disorder.</p

    The Cultural Project : Formal Chronological Modelling of the Early and Middle Neolithic Sequence in Lower Alsace

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    Starting from questions about the nature of cultural diversity, this paper examines the pace and tempo of change and the relative importance of continuity and discontinuity. To unravel the cultural project of the past, we apply chronological modelling of radiocarbon dates within a Bayesian statistical framework, to interrogate the Neolithic cultural sequence in Lower Alsace, in the upper Rhine valley, in broad terms from the later sixth to the end of the fifth millennium cal BC. Detailed formal estimates are provided for the long succession of cultural groups, from the early Neolithic Linear Pottery culture (LBK) to the Bischheim Occidental du Rhin Supérieur (BORS) groups at the end of the Middle Neolithic, using seriation and typology of pottery as the starting point in modelling. The rate of ceramic change, as well as frequent shifts in the nature, location and density of settlements, are documented in detail, down to lifetime and generational timescales. This reveals a Neolithic world in Lower Alsace busy with comings and goings, tinkerings and adjustments, and relocations and realignments. A significant hiatus is identified between the end of the LBK and the start of the Hinkelstein group, in the early part of the fifth millennium cal BC. On the basis of modelling of existing dates for other parts of the Rhineland, this appears to be a wider phenomenon, and possible explanations are discussed; full reoccupation of the landscape is only seen in the Grossgartach phase. Radical shifts are also proposed at the end of the Middle Neolithic

    Characterisation of a Peripheral Neuropathic Component of the Rat Monoiodoacetate Model of Osteoarthritis

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    Joint degeneration observed in the rat monoiodoacetate (MIA) model of osteoarthritis shares many histological features with the clinical condition. The accompanying pain phenotype has seen the model widely used to investigate the pathophysiology of osteoarthritis pain, and for preclinical screening of analgesic compounds. We have investigated the pathophysiological sequellae of MIA used at low (1 mg) or high (2 mg) dose. Intra-articular 2 mg MIA induced expression of ATF-3, a sensitive marker for peripheral neuron stress/injury, in small and large diameter DRG cell profiles principally at levels L4 and 5 (levels predominated by neurones innervating the hindpaw) rather than L3. At the 7 day timepoint, ATF-3 signal was significantly smaller in 1 mg MIA treated animals than in the 2 mg treated group. 2 mg, but not 1 mg, intra-articular MIA was also associated with a significant reduction in intra-epidermal nerve fibre density in plantar hindpaw skin, and produced spinal cord dorsal and ventral horn microgliosis. The 2 mg treatment evoked mechanical pain-related hypersensitivity of the hindpaw that was significantly greater than the 1 mg treatment. MIA treatment produced weight bearing asymmetry and cold hypersensitivity which was similar at both doses. Additionally, while pregabalin significantly reduced deep dorsal horn evoked neuronal responses in animals treated with 2 mg MIA, this effect was much reduced or absent in the 1 mg or sham treated groups. These data demonstrate that intra-articular 2 mg MIA not only produces joint degeneration, but also evokes significant axonal injury to DRG cells including those innervating targets outside of the knee joint such as hindpaw skin. This significant neuropathic component needs to be taken into account when interpreting studies using this model, particularly at doses greater than 1 mg MIA

    The consumption of work: representations and interpretations of the meaning of work at a UK university

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    This paper focuses on representations of the nexus of work, meaning and consumption as experienced by university students. We develop an empirically based argument that the meaning of work is being constructed as an object of consumption on a British university campus. We suggest that this indicates two key changes in representations of the meaning of work. First, there is a significant shift in the social construction of orientations to work towards what we term ‘consumption of work’. Second, we argue that this new social construction is made up of three dimensions: consumption of an idealised image of work, consumption through specific work processes and consumption of self-development opportunities at work. We conclude by suggesting ways in which this argument could be researched further

    Controlling irregular migration: International human rights standards and the Hungarian legal framework

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    In the summer of 2015 Hungary constructed a 175 km long barbed-wire fence at its southern border with Serbia. New criminal offences and asylum procedures were introduced that limited access to refugee status determination and ignored agreed EU asylum policy, deterring and de facto preventing asylum seekers from entering Hungarian territory. This paper provides an analysis of these new measures, which criminalized asylum seekers, and the subsequent Hungarian policy in relation to the case law of the European Court of Human Rights – arguing that the Hungarian authorities excessively abused their discretion in implementing these new policies of immigration and border control
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