How input processing factors into lexical semantics: Motion events with double particles in L3 German

Motion events are almost absent in the course syllabus of L2 German as a formally addressed structure in the classroom. Learners have merely receptive contact with this type of structure in reading texts or in aural activities. The occurrence of motion events with the so-called “double particles” is even less frequent. These are composed of the deictic morphemes hin- and her- denoting the speaker’s perspective and Path morphemes (-ein-, -aus-, -auf-, etc.). The main goal of the present study is to test a group of Portuguese L3 learners of German regarding their knowledge of double particles, and to apply VanPatten’s Processing Instruction (PI) model (VanPatten 2004; VanPatten and Williams 2015), which rests on an input-based focus-on-form approach for teaching grammar. The theoretical framework is based on Talmy’s typology of motion events (Talmy 2000a, 2000b). The empirical component of this study was divided into three parts: first, I tested the participants by means of a pretest; then, I conducted a pedagogical intervention based on the PI model; finally, a posttest determined the successful effects of PI in the participants’ knowledge of the target forms, both in interpretative and productive contexts.I would like to thank Cristina Flores for her diligent coordination during the realization ofthis study and for her insightful and constructive comments on earlier versions of this pap

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models.

Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes of hypoxia, and other undetermined causes, PH is associated with poor outcomes and a high rate of morbidity. In the neonate, this disease has a similar etiology but is further complicated by the transition to breathing after birth, which requires a reduction in vascular resistance. Persistent pulmonary hypertension of the newborn (PPHN) is one form of PH that is frequently unresponsive to current therapies including inhaled nitric oxide (due to lack of proper absorption and diffusion), and other therapeutics targeting signaling mediators in vascular endothelium and smooth muscle. The need for novel agents, which target distinct pathways in pulmonary hypertension, remains. Herein, we investigated the therapeutic effects of novel muscarinic receptor ligand C1213 in models of PH We demonstrated that via M3 muscarinic receptors, C1213 induced activating- eNOS phosphorylation (serine-1177), which is known to lead to nitric oxide (NO) production in endothelial cells. Using signaling pathway inhibitors, we discovered that AKT and calcium signaling contributed to eNOS phosphorylation induced by C1213. As expected for an eNOS-stimulating agent, in ex vivo and in vivo models, C1213 triggered pulmonary vasodilation and induced both pulmonary artery and systemic blood pressure reductions demonstrating its potential value in PH and PPHN In brief, this proof-of-concept study provides evidence that an M3 muscarinic receptor functionally selective ligand stimulates downstream pathways leading to antihypertensive effects using in vitro, ex vivo, and in vivo models of PH

Production and processing asymmetries in the acquisition of tense morphology by sequential bilingual children

This study investigates the production and on-line processing of English tense morphemes by sequential bilingual (L2) Turkish-speaking children with more than three years of exposure to English. Thirty nine 6-9-year-old L2 children and 28 typically developing age-matched monolingual (L1) children were administered the production component for third person –s and past tense of the Test for Early Grammatical Impairment (Rice & Wexler, 1996) and participated in an on-line word-monitoring task involving grammatical and ungrammatical sentences with presence/omission of tense (third person –s, past tense -ed) and non-tense (progressive –ing, possessive ‘s) morphemes. The L2 children’s performance on the on-line task was compared to that of children with Specific Language Impairment (SLI) in Montgomery & Leonard (1998, 2006) to ascertain similarities and differences between the two populations. Results showed that the L2 children were sensitive to the ungrammaticality induced by the omission of tense morphemes, despite variable production. This reinforces the claim about intact underlying syntactic representations in child L2 acquisition despite non target-like production (Haznedar & Schwartz, 1997)

Eye gaze and production accuracy predict English L2 speakers' morphosyntactic learning

This study investigated the relationship between second language (L2) speakers’ success in learning a new morphosyntactic pattern and characteristics of one-on-one learning activities, including opportunities to comprehend and produce the target pattern, receive feedback from an interlocutor, and attend to the meaning of the pattern through self- and interlocutor-initiated eye-gaze behaviors. L2 English students (N = 48) were exposed to the transitive construction in Esperanto (e.g., filino mordas pomon [SVO] or pomon mordas filino [OVS] “girl bites apple”) through comprehension and production activities with an interlocutor, receiving feedback in the form of recasts for their Esperanto errors. The L2 speakers’ interpretation and production of Esperanto transitives were then tested using known and novel lexical items. The results indicated that OVS test performance was predicted by the duration of self-initiated eye gaze to images illustrating the OVS pattern during the comprehension learning activity and by accurate production of OVS sentences during the production learning activity. The findings suggest important roles for eye-gaze behavior and production opportunities in L2 pattern learning.</jats:p

The Roles of First Language and Proficiency in L2 Processing of Spanish Clitics: Global Effects

We assessed the roles of first language (L1) and second language (L2) proficiency in the processing of preverbal clitics in L2 Spanish by considering the predictions of four processing theories—the Input Processing Theory, the Unified Competition Model, the Amalgamation Model, and the Associative-Cognitive CREED. We compared the performance of L1 English (typologically different from Spanish) to L1 Romanian (typologically similar to Spanish) speakers from various L2 Spanish proficiency levels on an auditory sentence-processing task. We found main effects of proficiency, condition, and L1 and an interaction between proficiency and condition. Although we did not find an interaction between L1 and condition, the L1 Romanians showed an overall advantage that may be attributable to structure-specific experience in the L1, raising new questions about how crosslinguistic differences influence the processing strategies learners apply to their L2

Multisite replication in SLA research: attention to form during listening and reading comprehension

We conducted a multi-site replication study with aspects of pre-registration in order to explore the feasibility of such an approach in second language (L2) research. To this end, we addressed open questions in a line of research that has examined whether having learners attend to form while reading or listening to a L2 passage interferes with comprehension (VanPatten, 1990; Leow, Hsieh, & Moreno, 2008). Our results are consistent with findings from the specific paradigm that we replicated (i.e., Leow et al., 2008) in that no effects were detected in analyses conducted over all sites. However, further investigation is warranted due to site-specific effects and methodological limitations. We found all aspects of the multi-site registered replication approach to be useful, although the registration component itself appears to be a more feasible and useful first step in order to increase the robustness and generalizability of findings in our field