Diseño de la estructura de los procedimientos, procesos y funciones por procesos de la empresa Condivalle

El área administrativa de ALIÑOS CONDIVALLE, desarrolla su actividad en el medio más dinámico buscando liberar a la empresa de actividades administrativas improductivas a través de excelentes metodologías de mejoramiento continuo que comprenden: mejoramiento continúo de los procesos, desarrollo y atención del talento humano, flujo y diagramación de procesos, elaboración de manuales de funciones y procedimientos. Dotamos a la empresa de un instrumento formal de trabajo que permita orientar al talento humano hacia un nivel optimo en el desarrollo de sus funciones, indicándole procedimientos de rutina y actividades diarias ciñéndose a las políticas y practicas internas de común acuerdo con el nivel, la categoría y las necesidades especificas de cada funcionario. Este documento detalla las funciones de los cargos plasmados en el organigrama institucional, ha sido trabajado tomando procesos básicos que sirven de parámetro para la distribución de funciones en un modelo organizacional. El proceso organizacional de la empresa debe ser visto como un sistema que tiene por una parte, la entrada de insumos, el procesamiento de los mismos y la salida de productos y/o servicios

Sistemas de Garantía participativo en Bogotá

In Colombia, there are several organizations developing agro-ecological processes within the framework of territorial ownership, food sovereignty, fair trade and environmental and cultural heritage conservation. The goal of these rural, indigenous and urban farmers' organizations is to provide good quality food, as well as other products, both for local consumption and for consumption in urban centers. The text it's a quick view of the status of the PGS in colombia

Modelling the NO emissions from wildfires at the source level

There is a growing interest to characterize fire plumes in order to control air quality during wildfire episodes and to estimate the carbon and ozone balance of fire emissions. A numerical approach has been used to study the mechanisms of NO formation at the source level in wildfires given that NO plays an important role in the formation of ground-level ozone. The major reaction mechanisms involved in NO chemistry have been identified using reaction path analysis. Accordingly, a two-step global kinetic scheme in the gas phase has been proposed herein to account for the volatile fuel-bound nitrogen (fuel-N) conversion to NO, considering that the volatile fraction of fuel-N is released as NH₃. Data from simulations using the perfectly stirred reactor (PSR) code from CHEMKIN-II package with a detailed kinetic mechanism (GDF-Kin^® 3.0) have been used to calibrate and evaluate the global model under typical wildfire conditions in terms of the composition of the degradation gases of vegetation, the equivalence ratio, the range of temperatures and the residence time

Transcriptome analysis of differential gene expression in disease

Many diseases strongly impact the human transcriptome at the gene expression level [1]. However, previous work has focused on accessible tissues [2], and has not incorporated the effect of demographic traits, known risk factors for complex diseases [3]. Here, we leveraged the GTEx dataset to investigate the gene expression changes associated with different diseases. By studying the transcriptomes from an organismal perspective -across tissues and individuals- we can gain deeper insights into disease biology and help preventing complex diseases

Tunable crystal structure and proton conductivity of lanthanide nitrilotrismethylphosphonates

Metal phosphonates are multifunctional solids with remarkable stability and proton conducting properties owing to their structure is usually composed of extended hydrogen-bond networks that favor proton transfer pathways [1]. Moreover, these properties can be enhanced by appropriate modification of the synthesis conditions [2, 3]. In this communication, a new family of isostructural 2D layered compounds based on lanthanide nitrilotris-methylphosphonates is reported. These compounds have been isolated at room temperature and have the general formula Ln[N(CH2)3(PO3H2)2(PO3H)(H2O)]SO4·2H2O (Ln= Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er and Yb). The coordination environment of Ln3+ is composed by eight oxygen atoms from three different ligands and two oxygens from bound waters. This connectivity creates positive charged layers connected to sulfate ions through hydrogen-bonds. These compounds show promising proton conductivity with values ranging between 7.6·10-2 and 3.8·10-2 S·cm-1 at 80 °C and 95% RH and low activation energy corresponding to Grotthuss-type proton transfer mechanism. In addition, a structural transformation occurs at T > 70 °C accompanied by a remarkable enhanced conductivity. Studies on the structure-properties relationships will be discussed.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. MINECO: MAT2016-77648-R Junta Andalucía: P12-FQM-1656 y FQM-11

Ventas Análisis y procesos en las estratégias de ventas

El presente documento tiene por tema general ventas las cuales son una de las actividades más importante dentro de las empresas debido a que estas generan ingresos, implementando un buen análisis y proceso de estrategias de ventas podemos llegar a los factores que motivan al consumidor al momento de adquirir un producto o servicio. En lo que se refiere a la investigación consiste en las generalidades de los planes y estrategias de ventas, comprender que son las estrategias de ventas, que factores influyen en el comportamiento del consumidor y la importancia que tiene el comportamiento del consumidor para las empresas, también detalla el propósito, tamaño de la fuerza de venta y la importancia de los canales de distribución. Esta investigación se realizó de manera documental, a través de consultas a libros escritos por investigadores especializados en la temática de ventas y marketing, que nos brindaron el referente bibliográfico para instruirnos en el tema y poder plasmar los conceptos más importantes en el informe

Matching in vitro bioaccessibility of polyphenols and antioxidant capacity of soluble coffee by Boosted Regression Trees

The aim of this study was to evaluate changes in polyphenol profile and antioxidant capacity of five soluble coffees throughout a simulated gastro-intestinal digestion, including absorption through a dialysis membrane. Our results demonstrate that both polyphenol content and antioxidant capacity were characteristic for each type of studied coffee, showing a drop after dialysis. Twenty-seven compounds were identified in coffee by HPLC-MS, while only 14 of them were found after dialysis. Green+roasted coffee blend and chicory+coffee blend showed the highest and lowest content of polyphenols and antioxidant capacity before in vitro digestion and after dialysis, respectively. Canonical correlation analysis showed significant correlation between the antioxidant capacity and the polyphenol profile before digestion and after dialysis. Furthermore, boosted regression trees analysis (BRT) showed that only four polyphenol compounds (5-p-coumaroylquinic acid, quinic acid, coumaroyl tryptophan conjugated, and 5-O-caffeoylquinic acid) appear to be the most relevant to explain the antioxidant capacity after dialysis, these compounds being the most bioaccessible after dialysis. To our knowledge, this is the first report matching the antioxidant capacity of foods with the polyphenol profile by BRT, which opens an interesting method of analysis for future reports on the antioxidant capacity of foods.Fil: Podio, Natalia Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Ciencia y Tecnología de Alimentos Córdoba; ArgentinaFil: López Froilán, Rebeca. Universidad Complutense de Madrid; EspañaFil: Ramirez Moreno, Esther. Universidad Autónoma de Estado de Hidalgo; México. Universidad Complutense de Madrid; EspañaFil: Bertrand, Lidwina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Baroni, María Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Ciencia y Tecnología de Alimentos Córdoba; ArgentinaFil: Pérez Rodríguez, María L.. Universidad Complutense de Madrid; EspañaFil: Sánchez Mata, María Cortes. Universidad Complutense de Madrid; EspañaFil: Wunderlin, Daniel A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Ciencia y Tecnología de Alimentos Córdoba; Argentin

Optimizing Energy Transduction of Fluctuating Signals with Nanofluidic Diodes and Load Capacitors

This is the peer reviewed version of the following article: Ramirez Hoyos, P.; Cervera Montesinos, J.; Gómez Lozano, V.; Ali, M.; Nasir, S.; Ensinger, W.; Mafé, S. (2018). Optimizing Energy Transduction of Fluctuating Signals with Nanofluidic Diodes and Load Capacitors. Small. 14(18). doi:10.1002/smll.201702252, which has been published in final form at http://doi.org/10.1002/smll.201702252. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."[EN] The design and experimental implementation of hybrid circuits is considered allowing charge transfer and energy conversion between nanofluidic diodes in aqueous ionic solutions and conventional electronic elements such as capacitors. The fundamental concepts involved are reviewed for the case of fluctuating zero-average external potentials acting on single pore and multipore membranes. This problem is relevant to electrochemical energy conversion and storage, the stimulus-response characteristics of nanosensors and actuators, and the estimation of the accumulative effects caused by external signals on biological ion channels. Half-wave and full-wave voltage doublers and quadruplers can scale up the transduction between ionic and electronic signals. The network designs discussed here should be useful to convert the weak signals characteristic of the micro and nanoscale into robust electronic responses by interconnecting iontronics and electronic elements.P.R., J.C., V.G., and S.M. acknowledge the financial support from the Ministry of Economy and Competitiveness of Spain, (Materials Program, project No. MAT2015-65011-P), and FEDER. M.A., S.N., and W.E. acknowledge the funding from the Hessen State Ministry of Higher Education, Research and the Arts, Germany, under the LOEWE project iNAPO.Ramirez Hoyos, P.; Cervera Montesinos, J.; Gómez Lozano, V.; Ali, M.; Nasir, S.; Ensinger, W.; Mafé, S. (2018). Optimizing Energy Transduction of Fluctuating Signals with Nanofluidic Diodes and Load Capacitors. Small. 14(18). https://doi.org/10.1002/smll.201702252S1418Misra, N., Martinez, J. A., Huang, S.-C. J., Wang, Y., Stroeve, P., Grigoropoulos, C. P., & Noy, A. (2009). Bioelectronic silicon nanowire devices using functional membrane proteins. Proceedings of the National Academy of Sciences, 106(33), 13780-13784. doi:10.1073/pnas.0904850106Lemay, S. G. (2009). Nanopore-Based Biosensors: The Interface between Ionics and Electronics. ACS Nano, 3(4), 775-779. doi:10.1021/nn900336jTybrandt, K., Larsson, K. C., Richter-Dahlfors, A., & Berggren, M. (2010). Ion bipolar junction transistors. Proceedings of the National Academy of Sciences, 107(22), 9929-9932. doi:10.1073/pnas.0913911107Duan, X., Fu, T.-M., Liu, J., & Lieber, C. M. (2013). Nanoelectronics-biology frontier: From nanoscopic probes for action potential recording in live cells to three-dimensional cyborg tissues. Nano Today, 8(4), 351-373. doi:10.1016/j.nantod.2013.05.001Ramirez, P., Cervera, J., Ali, M., Ensinger, W., & Mafe, S. (2014). Logic Functions with Stimuli-Responsive Single Nanopores. ChemElectroChem, 1(4), 698-705. doi:10.1002/celc.201300255Guan, W., Li, S. X., & Reed, M. A. (2014). Voltage gated ion and molecule transport in engineered nanochannels: theory, fabrication and applications. Nanotechnology, 25(12), 122001. doi:10.1088/0957-4484/25/12/122001Tagliazucchi, M., & Szleifer, I. (2015). Transport mechanisms in nanopores and nanochannels: can we mimic nature? Materials Today, 18(3), 131-142. doi:10.1016/j.mattod.2014.10.020Ramirez, P., Gomez, V., Ali, M., Ensinger, W., & Mafe, S. (2013). Net currents obtained from zero-average potentials in single amphoteric nanopores. Electrochemistry Communications, 31, 137-140. doi:10.1016/j.elecom.2013.03.026Gomez, V., Ramirez, P., Cervera, J., Nasir, S., Ali, M., Ensinger, W., & Mafe, S. (2015). Converting external potential fluctuations into nonzero time-average electric currents using a single nanopore. Applied Physics Letters, 106(7), 073701. doi:10.1063/1.4909532Gomez, V., Ramirez, P., Cervera, J., Nasir, S., Ali, M., Ensinger, W., & Mafe, S. (2015). Charging a Capacitor from an External Fluctuating Potential using a Single Conical Nanopore. Scientific Reports, 5(1). doi:10.1038/srep09501Queralt-Martín, M., García-Giménez, E., Aguilella, V. M., Ramirez, P., Mafe, S., & Alcaraz, A. (2013). Electrical pumping of potassium ions against an external concentration gradient in a biological ion channel. Applied Physics Letters, 103(4), 043707. doi:10.1063/1.4816748Verdia-Baguena, C., Gomez, V., Cervera, J., Ramirez, P., & Mafe, S. (2017). Energy transduction and signal averaging of fluctuating electric fields by a single protein ion channel. Physical Chemistry Chemical Physics, 19(1), 292-296. doi:10.1039/c6cp06035hGomez, V., Cervera, J., Nasir, S., Ali, M., Ensinger, W., Mafe, S., & Ramirez, P. (2016). Electrical network of nanofluidic diodes in electrolyte solutions: Connectivity and coupling to electronic elements. Electrochemistry Communications, 62, 29-33. doi:10.1016/j.elecom.2015.10.022Ramirez, P., Gomez, V., Verdia-Baguena, C., Nasir, S., Ali, M., Ensinger, W., & Mafe, S. (2016). Designing voltage multipliers with nanofluidic diodes immersed in aqueous salt solutions. Physical Chemistry Chemical Physics, 18(5), 3995-3999. doi:10.1039/c5cp07203dRamirez, P., Gomez, V., Cervera, J., Nasir, S., Ali, M., Ensinger, W., … Mafe, S. (2016). Voltage-controlled current loops with nanofluidic diodes electrically coupled to solid state capacitors. RSC Advances, 6(60), 54742-54746. doi:10.1039/c6ra08277gRamirez, P., Garcia-Morales, V., Gomez, V., Ali, M., Nasir, S., Ensinger, W., & Mafe, S. (2017). Hybrid Circuits with Nanofluidic Diodes and Load Capacitors. Physical Review Applied, 7(6). doi:10.1103/physrevapplied.7.064035Ramirez, P., Gomez, V., Cervera, J., Nasir, S., Ali, M., Ensinger, W., & Mafe, S. (2015). Energy conversion from external fluctuating signals based on asymmetric nanopores. Nano Energy, 16, 375-382. doi:10.1016/j.nanoen.2015.07.013Hou, Y., Vidu, R., & Stroeve, P. (2011). Solar Energy Storage Methods. Industrial & Engineering Chemistry Research, 50(15), 8954-8964. doi:10.1021/ie2003413Ali, M., Ahmed, I., Ramirez, P., Nasir, S., Mafe, S., Niemeyer, C. M., & Ensinger, W. (2017). A redox-sensitive nanofluidic diode based on nicotinamide-modified asymmetric nanopores. Sensors and Actuators B: Chemical, 240, 895-902. doi:10.1016/j.snb.2016.09.061Zhang, Y., & Schatz, G. C. (2017). Conical Nanopores for Efficient Ion Pumping and Desalination. The Journal of Physical Chemistry Letters, 8(13), 2842-2848. doi:10.1021/acs.jpclett.7b01137Apel, P. (2001). Track etching technique in membrane technology. Radiation Measurements, 34(1-6), 559-566. doi:10.1016/s1350-4487(01)00228-1Siwy, Z., Trofin, L., Kohli, P., Baker, L. A., Trautmann, C., & Martin, C. R. (2005). Protein Biosensors Based on Biofunctionalized Conical Gold Nanotubes. Journal of the American Chemical Society, 127(14), 5000-5001. doi:10.1021/ja043910fRamirez, P., Ali, M., Ensinger, W., & Mafe, S. (2012). Information processing with a single multifunctional nanofluidic diode. Applied Physics Letters, 101(13), 133108. doi:10.1063/1.4754845Cervera, J., Ramirez, P., Gomez, V., Nasir, S., Ali, M., Ensinger, W., … Mafe, S. (2016). Multipore membranes with nanofluidic diodes allowing multifunctional rectification and logical responses. Applied Physics Letters, 108(25), 253701. doi:10.1063/1.4954764Nasir, S., Ramirez, P., Ali, M., Ahmed, I., Fruk, L., Mafe, S., & Ensinger, W. (2013). Nernst-Planck model of photo-triggered, pH–tunable ionic transport through nanopores functionalized with «caged» lysine chains. The Journal of Chemical Physics, 138(3), 034709. doi:10.1063/1.4775811Pérez-Mitta, G., Albesa, A. G., Trautmann, C., Toimil-Molares, M. E., & Azzaroni, O. (2017). Bioinspired integrated nanosystems based on solid-state nanopores: «iontronic» transduction of biological, chemical and physical stimuli. Chemical Science, 8(2), 890-913. doi:10.1039/c6sc04255dGuo, W., Cao, L., Xia, J., Nie, F.-Q., Ma, W., Xue, J., … Jiang, L. (2010). Energy Harvesting with Single-Ion-Selective Nanopores: A Concentration-Gradient-Driven Nanofluidic Power Source. Advanced Functional Materials, 20(8), 1339-1344. doi:10.1002/adfm.200902312Roseman, J. M., Lin, J., Ramakrishnan, S., Rosenstein, J. K., & Shepard, K. L. (2015). Hybrid integrated biological–solid-state system powered with adenosine triphosphate. Nature Communications, 6(1). doi:10.1038/ncomms10070Kocer, A., Tauk, L., & Déjardin, P. (2012). Nanopore sensors: From hybrid to abiotic systems. Biosensors and Bioelectronics, 38(1), 1-10. doi:10.1016/j.bios.2012.05.013Maglia, G., Heron, A. J., Hwang, W. L., Holden, M. A., Mikhailova, E., Li, Q., … Bayley, H. (2009). Droplet networks with incorporated protein diodes show collective properties. Nature Nanotechnology, 4(7), 437-440. doi:10.1038/nnano.2009.121Han, J.-H., Kim, K. B., Kim, H. C., & Chung, T. D. (2009). Ionic Circuits Based on Polyelectrolyte Diodes on a Microchip. Angewandte Chemie International Edition, 48(21), 3830-3833. doi:10.1002/anie.200900045Ali, M., Ramirez, P., Nguyen, H. Q., Nasir, S., Cervera, J., Mafe, S., & Ensinger, W. (2012). Single Cigar-Shaped Nanopores Functionalized with Amphoteric Amino Acid Chains: Experimental and Theoretical Characterization. ACS Nano, 6(4), 3631-3640. doi:10.1021/nn3010119Vlassiouk, I., & Siwy, Z. S. (2007). Nanofluidic Diode. Nano Letters, 7(3), 552-556. doi:10.1021/nl062924bCervera, J., Ramirez, P., Mafe, S., & Stroeve, P. (2011). Asymmetric nanopore rectification for ion pumping, electrical power generation, and information processing applications. Electrochimica Acta, 56(12), 4504-4511. doi:10.1016/j.electacta.2011.02.056Ramírez, P., Rapp, H.-J., Mafé, S., & Bauer, B. (1994). Bipolar membranes under forward and reverse bias conditions. Theory vs. experiment. Journal of Electroanalytical Chemistry, 375(1-2), 101-108. doi:10.1016/0022-0728(94)03379-xHou, X., Guo, W., & Jiang, L. (2011). Biomimetic smart nanopores and nanochannels. Chemical Society Reviews, 40(5), 2385. doi:10.1039/c0cs00053aGuo, W., Tian, Y., & Jiang, L. (2013). Asymmetric Ion Transport through Ion-Channel-Mimetic Solid-State Nanopores. Accounts of Chemical Research, 46(12), 2834-2846. doi:10.1021/ar400024