Using the local positioning system based on Pulse Width Modulation for Robot Positioning

There are many ways to estimate the location of a moving object. One way is to determine its location using a GPS which calculates longitude and latitude of the object by the data received by the satellites rotating around the earth. However, there are no devices to recover calculated inherent errors and have an appropriate estimated signal. From robots' place, we should correct the errors made by collected data from sensors. A problem happening alternatively in the landmark identifying a method is the similar sharing data. The data obtained should be related to correcting land mark. Even though, some landmarks are likely to be similar. In addition, it is impossible to guarantee sightseeing line among landmarks in some arrangements. The other methods are to utilize radio frequency stations, which are placed around the robot by which we can find the real place of source of measurement error. In non-isolated environments, due to noises in signals using such a system should be investigated. In this PAPER, LPS (local positioning system) and the way it influences interference signals on the simulated system has been studied. A method has been tried to present in order to decrease destructive effects of noise using GA (genetic algorithm). In this way, the LPS modulation method and factors which cause interference signal and noises in the system have been stated. The obtained results have been illustrated by different simulations followed by discussions

Monitoring Occupancy and Office Equipment Energy Consumption Using Real-Time Location System and Wireless Energy Meters

Buildings are one of the major energy consumers because of the need to meet occupants’ requirements. The commercial/institutional sector accounted for 14% of total energy consumption in Canada in 2009 while office buildings consumed 35% of this amount. Auxiliary equipment used 19% of the total energy consumed in office buildings. Previous studies showed the impact of occupancy behavior on IT equipment energy consumption. This thesis proposes a new method for monitoring occupancy behavior and energy consumption of IT equipment. Two wireless sensor technologies are investigated to collect the required data and to build an occupancy behavior estimation profile: Ultra-Wideband Real-Time Location System for occupancy location monitoring and ZigBee wireless energy meters for monitoring the energy consumption of IT equipment. The occupancy monitoring data gained from the UWB are used to create the occupants’ hourly profile. The occupancy profile based on short-time monitoring can be used to simulate long-term energy consumption. In conclusion, the comparison between the results shows up to 11% and 24% saving for heating loads and cooling loads, respectively. The proposed method profiles also resulted in up to 65% and 78% reduction for lighting and IT equipment energy consumption in the office, respectively. Therefore, dynamic occupancy driven profiles will reduce the energy consumption

Using the local positioning system based on Pulse Width Modulation for Robot Positioning

There are many ways to estimate the location of a moving object. One way is to determine its location using a GPS which calculates longitude and latitude of the object by the data received by the satellites rotating around the earth. However, there are no devices to recover calculated inherent errors and have an appropriate estimated signal. From robots' place, we should correct the errors made by collected data from sensors. A problem happening alternatively in the landmark identifying a method is the similar sharing data. The data obtained should be related to correcting land mark. Even though, some landmarks are likely to be similar. In addition, it is impossible to guarantee sightseeing line among landmarks in some arrangements. The other methods are to utilize radio frequency stations, which are placed around the robot by which we can find the real place of source of measurement error. In non-isolated environments, due to noises in signals using such a system should be investigated. In this PAPER, LPS (local positioning system) and the way it influences interference signals on the simulated system has been studied. A method has been tried to present in order to decrease destructive effects of noise using GA (genetic algorithm). In this way, the LPS modulation method and factors which cause interference signal and noises in the system have been stated. The obtained results have been illustrated by different simulations followed by discussions

Health care-associated infections, including device-associated infections, and antimicrobial resistance in Iran: The national update for 2018

Introduction. Surveillance of health care-associated infections (HAIs) is an essential part of an efficient healthcare system. This study is an update on incidence and mortality rates of HAIs in Iran in 2018. Methods. Almost all hospitals across the country (940 hospitals) entered the data of HAIs and denominators to the Iranian Nosocomial Infections Surveillance (INIS) software. Statistics were derived from INIS. Results. From 9,607,213 hospitalized patients, 127,953 suffered from HAI, 15.65% of whom died. The incidence rate of HAI was calculated as 4.2 per 1000 patient-days. Considering relative frequencies among HAIs, Pneumonia (29.1%) and UTIs (25.6%) were the most common types of infection. Ventilator-associated pneumonia (VAP) was the most frequent device-associated infection (DAI) 25.66 per 1000 ventilator-days, and had the highest mortality rate (43.08%). Incidence density of other DAIs was 5.43 for catheter-associated UTI and 2.86 for catheter-associated BSI per 1000 device-days. Medical ICUs had the highest incidence and percentage of deaths (15.35% and 37.63%, respectively). The most causative organisms were Escherichia coli, Acinetobacter baumannii, and Klebsiella pneumonia. The rate of methicillin-resistance Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria was about 49%, 57%, and 58% respectively. Conclusion. The findings indicate that HAIs in Iran require special attention, and further studies are needed to evaluate them more accurately, identify risk factors and preventive interventions

The therapeutic potential of human adipose-derived mesenchymal stem cells producing CXCL10 in a mouse melanoma lung metastasis model

Abstract Interferon γ-induced protein 10 kDa (IP-10) is a potent chemoattractant and has been suggested to enhance antitumor activity and mediate tumor regression through multiple mechanisms of action. Multiple lines of evidence have indicated that genetically-modified adult stem cells represent a potential source for cell-based cancer therapy. In the current study, we assessed therapeutic potential of human adipose derived mesenchymal stem cells (hADSC) genetically-modified to express IP-10 for the treatment of lung metastasis in an immunocompetent mouse model of metastatic melanoma. A Piggybac vector encoding IP-10 was employed to transfect hADSC ex vivo. Expression and bioactivity of the transgenic protein from hADSCs expressing IP-10 were confirmed prior to in vivo studies. Our results indicated that hADSCs expressing IP-10 could inhibit the growth of B16F10 melanoma cells and significantly prolonged survival. Immunohistochemistry analysis, TUNEL assay and western blot analysis indicated that hADSCs expressing IP-10 inhibited tumor cell growth, hindered tumor infiltration of Tregs, restricted angiogenesis and significantly prolonged survival. In conclusion, our results demonstrated that targeting metastatic tumor sites by hADSC expressing IP-10 could reduce melanoma tumor growth and lung metastasis. Keywords: Melanoma Metastasis Human adipose derived mesenchymal stem cells CXCL1

The impact of occupants’ behaviours on building energy analysis: A research review

Over the past 15 years, the evaluation of energy demand and use in buildings has become increasingly acute due to growing scientific and political pressure around the world in response to climate change. The estimation of the use of energy in buildings is therefore a critical process during the design stage. This paper presents a review of the literature published in leading journals through Science Direct and Scopus databases within this research domain to establish research trends, and importantly, to identify research gaps for future investigation. It has been widely acknowledged in the literature that there is an alarming performance gap between the predicted and actual energy consumption of buildings (sometimes this has been up to 300% difference). Analysis of the impact of occupants’ behaviour has been largely overlooked in building energy performance analysis. In short, energy simulation tools utilise climatic data and physical/ thermal properties of building elements in their calculations, and the impact of occupants is only considered through means of fixed and scheduled patterns of behaviour. This research review identified a number of areas for future research including: larger scale analysis (e.g. urban analysis); interior design, in terms of space layout, and fixtures and fittings on occupants’ behaviour; psychological cognitive behavioural methods; and the integration of quantitative and qualitative research findings in energy simulation tools to name but a few

Boerhaave Syndrome

Boerhaave syndrome (BS) is a spontaneous esophageal perforation and is a life-threating but uncommon disorder. This syndrome involves a transmural perforation and typically occurs after forceful emesis. The prognosis is dependent on rapid diagnosis and correct management. The classic presentation of BS consists of vomiting, subcutaneous emphysema, and lower thoracic pain. However, significant symptoms and signs rarely occur, about one-third of all patients are clinically atypical. Thus, BS should be suspected in patients presenting any sudden thoracoabdominal pain with a history of emesis. The chest radiograph is the most helpful diagnostic aid, in addition to CT scans for further evaluations.When the clinical condition allows for a less invasive approach, non-operative treatment should be considered, with or without the use of an endoscopic stent or placement of internal or external drains. The best prognosis of Boerhaave's syndrome is associated with early diagnosis and surgical care within 12 hours of perforation