Why do older adults stand-up differently to young adults?: investigation of compensatory movement strategies in sit-to-walk

Functional motor redundancy enables humans to move with distinct muscle activation patterns while achieving a similar outcome. Since humans select similar strategies, there seems to be an optimal control. However, older adults move differently to young adults. The question is whether this is this due to an altered reinforcement scheme, altered sensory inputs, or due to alterations in the neuromusculoskeletal systems, so that it is no longer optimal or possible to execute the same movement strategies. The aim of this study was to analyse natural compensation strategies in the vital daily-life-task, sit-to-walk, in relation to neuromuscular capacity and movement objectives in younger (27.2 ± 4.6 years, N = 27, 14♀) and elderly (75.9 ± 6.3 years, N = 23, 12♀) adults. Aspects of the neuromuscular system that are prone to age-related decline and feasible to quantify were assessed (i.e. strength, nerve conductivity, fear of falling). Kinematics and muscle activity were recorded and joint kinetics were estimated using biomechanical models. Elderly men consistently used their arms when standing up. This strategy was not associated with a lack of or a reduction in strength, but with a reduction, but no lack of, ankle joint range of motion, and with increased fear of falling. The results show that humans preferentially maintain a minimum threshold of neuromuscular reserve to cope with uncertainties which results in compensation prior to coming up against physical limitations. Smaller base of support while standing up, a compensatory strategy with possibly greater risk of falls, was associated with muscular weakness, and longer nerve conduction latencies

Linking satellite derived LAI patterns with subsoil heterogeneity using large-scale ground-based electromagnetic induction measurements

Patterns in crop development and yield are often directly related to lateral and vertical changes in soil texture causing changes in available water and resource supply for plant growth, especially under dry conditions. Relict geomorphologic features, such as old river channels covered by shallow sediments can challenge assumptions of uniformity in precision agriculture, subsurface hydrology, and crop modeling. Hence a better detection of these subsurface structures is of great interest. In this study, the origins of narrow and undulating leaf area index (LAI) patterns showing better crop performance in large scale multi-temporal satellite imagery were for the first time interpreted by proximal soil sensor data. A multi-receiver electromagnetic induction (EMI) sensor measuring soil apparent electrical conductivity (ECa) for six depths of exploration (DOE) ranging from 0–0.25 to 0–1.9 m was used as reconnaissance soil survey tool in combination with selected electrical resistivity tomography (ERT) transects, and ground truth texture data to investigate lateral and vertical changes of soil properties at ten arable fields. The moderate to excellent spatial consistency (R2 0.19–0.82) of ECa patterns and LAI crop marks that indicate a higher water storage capacity as well as the increased correlations between large-offset ECa data and the subsoil clay content and soil profile depth, implies that along this buried paleo-river structure the subsoil is mainly responsible for better crop development in drought periods. Furthermore, observed stagnant water in the subsoil indicates that this paleo-river structure still plays an important role in subsurface hydrology. These insights should be considered and implemented in local hydrological as well as crop models

Effect of galaxy mergers on star-formation rates

Context. Galaxy mergers and interactions are an integral part of our basic understanding of how galaxies grow and evolve over time. However, the effect that galaxy mergers have on star-formation rates (SFRs) is contested, with observations of galaxy mergers showing reduced, enhanced, and highly enhanced star formation. Aims. We aim to determine the effect of galaxy mergers on the SFR of galaxies using statistically large samples of galaxies, totalling over 200 000, which is over a large redshift range from 0.0 to 4.0. Methods. We trained and used convolutional neural networks to create binary merger identifications (merger or non-merger) in the SDSS, KiDS, and CANDELS imaging surveys. We then compared the SFR, with the galaxy main sequence subtracted, of the merging and non-merging galaxies to determine what effect, if any, a galaxy merger has on SFR. Results. We find that the SFR of merging galaxies are not significantly different from the SFR of non-merging systems. The changes in the average SFR seen in the star-forming population when a galaxy is merging are small, of the order of a factor of 1.2. However, the higher the SFR is above the galaxy main sequence, the higher the fraction is for galaxy mergers. Conclusions. Galaxy mergers have little effect on the SFR of the majority of merging galaxies compared to the non-merging galaxies. The typical change in SFR is less than 0.1 dex in either direction. Larger changes in SFR can be seen but are less common. The increase in merger fraction as the distance above the galaxy main sequence increases demonstrates that galaxy mergers can induce starbursts

Wide-Field InfraRed Survey Telescope (WFIRST) Final Report

In December 2010, NASA created a Science Definition Team (SDT) for WFIRST, the Wide Field Infra-Red Survey Telescope, recommended by the Astro 2010 Decadal Survey as the highest priority for a large space mission. The SDT was chartered to work with the WFIRST Project Office at GSFC and the Program Office at JPL to produce a Design Reference Mission (DRM) for WFIRST. Part of the original charge was to produce an interim design reference mission by mid-2011. That document was delivered to NASA and widely circulated within the astronomical community. In late 2011 the Astrophysics Division augmented its original charge, asking for two design reference missions. The first of these, DRM1, was to be a finalized version of the interim DRM, reducing overall mission costs where possible. The second of these, DRM2, was to identify and eliminate capabilities that overlapped with those of NASA's James Webb Space Telescope (henceforth JWST), ESA's Euclid mission, and the NSF's ground-based Large Synoptic Survey Telescope (henceforth LSST), and again to reduce overall mission cost, while staying faithful to NWNH. This report presents both DRM1 and DRM2.Comment: 102 pages, 57 figures, 17 table

Dynamic Myocardial Perfusion CT for the Detection of Hemodynamically Significant Coronary Artery Disease

OBJECTIVES In this international, multicenter study, using third-generation dual-source computed tomography (CT), we investigated the diagnostic performance of dynamic stress CT myocardial perfusion imaging (CT-MPI) in addition to coronary CT angiography (CTA) compared to invasive coronary angiography (ICA) and invasive fractional flow reserve (FFR). BACKGROUND CT-MPI combined with coronary CTA integrates coronary artery anatomy with inducible myocardial ischemia, showing promising results for the diagnosis of hemodynamically significant coronary artery disease in single-center studies. METHODS At 9 centers in Europe, Japan, and the United States, 132 patients scheduled for ICA were enrolled; 114 patients successfully completed coronary CTA, adenosine-stress dynamic CT-MPI, and ICA. Invasive FFR was performed in vessels with 25% to 90% stenosis. Data were analyzed by independent core laboratories. For the primary analysis, for each coronary artery the presence of hemodynamically significant obstruction was interpreted by coronary CTA with CT-MPI compared to coronary CTA alone, using an FFR of ≤0.80 and angiographic severity as reference. Territorial absolute myocardial blood flow (MBF) and relative MBF were compared using C-statistics. RESULTS ICA and FFR identified hemodynamically significant stenoses in 74 of 289 coronary vessels (26%). Coronary CTA with ≥50% stenosis demonstrated a per-vessel sensitivity, specificity, and accuracy for the detection of hemodynamically significant stenosis of 96% (95% CI: 91-100), 72% (95% CI: 66-78), and 78% (95% CI: 73-83), respectively. Coronary CTA with CT-MPI showed a lower sensitivity (84%; 95% CI: 75-92) but higher specificity (89%; 95% CI: 85-93) and accuracy (88%; 95% CI: 84-92). The areas under the receiver-operating characteristic curve of absolute MBF and relative MBF were 0.79 (95% CI: 0.71-0.86) and 0.82 (95% CI: 0.74-0.88), respectively. The median dose-length product of CT-MPI and coronary CTA were 313 mGy·cm and 138 mGy·cm, respectively. CONCLUSIONS Dynamic CT-MPI offers incremental diagnostic value over coronary CTA alone for the identification of hemodynamically significant coronary artery disease. Generalized results from this multicenter study encourage broader consideration of dynamic CT-MPI in clinical practice. (Dynamic Stress Perfusion CT for Detection of Inducible Myocardial Ischemia [SPECIFIC]; NCT02810795)

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes