Temperatura E Substrato Na Germinação De Sementes De Plukenetia Volubilis L.

The objective of this work was to evaluate the effect of temperature and substrate on the germination of P. volubilis seeds. Seeds harvested from 25 matrix plants were submitted, in two studies, to conditions of (i) sowing in rolled paper towel at the temperatures of 10, 15, 20, 25, 30, 35, 40, and 45 °C, for the evaluation of germination, first count of germination, germination speed index and mean time for germination, and (ii) sowing in the substrates paper towel, sand, Bioplant®, Bioplant® and micron, superfine, fine, medium and coarse vermiculite. The same evaluations mentioned in the first study were conducted at the temperature of 30 oC, as well as plant growth. The treatment replicates were distributed in a completely randomized block design and the effects of temperature were compared by polynomial regression analysis. The substrates were compared by the Scott-Knott test at 0.05 probability level. The data show that the ideal range of temperature for the germination of P. volubilis is between 25 and 30 °C. The temperature of 20 °C is the minimum for germination and those above 35 °C are lethal to these seeds. The most favorable substrate for P. volubilis seed germination is micron or fine vermiculite. © 2016, Departamento de Engenharia Agricola - UFCG/Cnpq. All rights reserved.20111031103

Heavy quarkonium: progress, puzzles, and opportunities

A golden age for heavy quarkonium physics dawned a decade ago, initiated by the confluence of exciting advances in quantum chromodynamics (QCD) and an explosion of related experimental activity. The early years of this period were chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in 2004, which presented a comprehensive review of the status of the field at that time and provided specific recommendations for further progress. However, the broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles could only be partially anticipated. Since the release of the YR, the BESII program concluded only to give birth to BESIII; the $B$-factories and CLEO-c flourished; quarkonium production and polarization measurements at HERA and the Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the deconfinement regime. All these experiments leave legacies of quality, precision, and unsolved mysteries for quarkonium physics, and therefore beg for continuing investigations. The plethora of newly-found quarkonium-like states unleashed a flood of theoretical investigations into new forms of matter such as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b}, and b\bar{c} bound states have been shown to validate some theoretical approaches to QCD and highlight lack of quantitative success for others. The intriguing details of quarkonium suppression in heavy-ion collisions that have emerged from RHIC have elevated the importance of separating hot- and cold-nuclear-matter effects in quark-gluon plasma studies. This review systematically addresses all these matters and concludes by prioritizing directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K. Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D. Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A. Petrov, P. Robbe, A. Vair

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Photothermally Modulated Magnetic Resonance Applied To The Study Of The Magnetic Phase Transition In Gadolinium Thin Films

We explore the photothermally modulated magnetic resonance technique to investigate gadolinium thin films deposited on fused quartz substrate, as a function of thickness and thermal treatment, around the magnetic phase transition temperature. It has been observed that the maximum amplitude of the photothermally modulated magnetic resonance (PM-MR) signal takes place near the phase transition temperature, similarly to the magnetocaloric effect, for which Gd has been the prototype material. The reason is that both depend on the temperature derivative of the magnetization, which maximizes at the phase transition. Besides, there is a narrowing of transition with thermal treatment, confirming that thermal treatment stabilizes the film structure. For frequency scan measurements, the heat diffusion in a two-layer system was considered, and a depth profile study was carried out in order to investigate heterogeneities along the film thickness. From the PM-MR response as a function of the modulation frequency it was possible to estimate the thermal properties of the Gd film. Magnetization, X-ray and electron spin resonance measurements were used to complement the analysis and support the conclusions. © 2011 Elsevier B.V. All rights reserved.520936343640Ohring, M., (1991) The Materials Science of Thin Films, , Academic Press New YorkPrutton, M., (1964) Thin Ferromagnetic Films, , Butterworth WashingtonPoole, Jr.C.P., (1983) Electron Spin Resonance, , John Wiley & Sons New YorkAbragam, A., Bleaney, B., (1986) Electron Paramagnetic Resonance of Transitions Ions, , Dover New YorkOrth, T., Netelmann, U., Pelzl, J., (1988) Appl. Phys. Lett., 53, p. 1979Romano, J.A., Mansanares, A.M., Da Silva, E.C., Vargas, H., (1994) J. Phys., 4, pp. C7-667Meckenstock, R., Spodding, D., Pelzl, J., (2002) J. Magn. Mater., 240, p. 83Pecharsky, V.K., Gschneider, Jr.K.A., (1997) Phys. Rev. Lett., 78, p. 4494Foldeaki, M., Schnelle, W., Gmelin, E., Bernard, P., Koszegi, B., Giguere, A., Chahine, R., Bose, T.K., (1997) J. Appl. Phys., 82, p. 309Tishin, A.M., Spichkin, Y.I., (2003) The Magnetocaloric Effect and Its Applications, , Institute of Physics Series in Condensed Matter Physics BristolMorelli, D.T., Mance, A.M., Mantese, J.M., Micheli, A.L., (1996) J. Appl. Phys., 79, p. 373Gadioli, G.Z., Rouxinol, F.P., Gelamo, R.V., Dos Santos, A.O., Cardoso, L.P., De Moraes, M.A.B., (2008) J. Appl. Phys., 103, p. 093916Recarte, V., Pérez-Landazábal, J.I., Sánchez- Alárcos, V., Chemenko, V.A., Ohtsuka, M., (2009) Appl. Phys. Lett., 95, p. 141908Solzi, M., Pernechele, C., Ghidini, M., Natali, M., Bolzan, M., (2010) J. Magn. Magn. Mater., 322, p. 1565Pelzl, J., Netzelmann, U., (1989) Topics in Currents Physics: Photoacoustic, Photothermal and Photochemical Processes at Surfaces and in Thin Films, p. 313. , P. Hess, Springer-Verlag BerlinGuimarães, A.O., Soffner, M.E., Mansanares, A.M., Coellho, A.A., Magnus, A., Carvalho, G., Pires, M.J.M., Da Silva, E.C., (2009) Phys. Rev. B, 80, p. 134406Guimarães, A.O., Soffner, M.E., Mansanares, A.M., Coellho, A.A., Magnus, A., Carvalho, G., Pires, M.J.M., Da Silva, E.C., (2010) J. Appl. Phys., 107, p. 073524Soffner, M.E., Tedesco, J.C.G., Mansanares, A.M., Gadioli, G.Z., Rouxinol, F.P., De Moraes, M.A.B., Da Silva, E.C., (2010) J. Phys. Conf. Ser., 214, p. 012092Nakamura, O., Baba, K., Ishii, H., Takeda, T., (1988) J. Appl. Phys., 64, p. 3614Farle, M., Baberschke, K., (1987) Phys. Rev. Lett., 58, p. 511Bugardt, P., Seehra, M.S., (1977) Phys. Rev. B, 16, p. 1802Chiba, Y., Nakamura, A., (1970) J. Phys. Soc. Jpn, 29, p. 792Freitas, L.R., Mansanares, A.M., Da Silva, E.C., (2003) Rev. Sci. Instrum., 74, p. 735Glorieux, C., Thoen, J., Bednarz, G., White, M.A., Geldart, D.J.W., (1995) Phys. Rev. B, 52, p. 12770Lide, D.R., (1991) CRC Handbook of Chemistry and Physics, , 72nd ed. CRC PressPetrakian, J.P., Ahmed Mokhtar, N., Fraisse, R., (1977) J. Phys. F: Met. Phys., 7, p. 2431Almond, D.P., Patel, P.M., (1996) Photothermal Science and Techniques, , Chapman & Hall LondonTouloukian, Y.S., Buyco, E.H., (1970) Thermophysical Properties of Matter, , IFI/Plenum New York-Washingto

Heterozygosis For Cyp21a2 Mutation Considered As 21-hydroxylase Deficiency In Neonatal Screening

Steroid 21-hydroxylase deficiency (21-OHD) accounts for more than 90% of congenital adrenal hyperplasia. CAH newborn screening, in general, is based on 17-hydroxyprogesterone dosage (17-OHP), however it is complicated by the fact that healthy preterm infants have high levels of 17-OHP resulting in false positive cases. We report on molecular features of a boy born pre-term (GA = 30 weeks; weight = 1,390 g) with elevated levels of 17-OHP (91.2 nmol/L, normal < 40) upon neonatal screening who was treated as having CAH up to the age of 8 months. He was brought to us for molecular diagnosis. Medication was gradually suspended and serum 17-OHP dosages mantained normal. The p.V281 L mutation was found in compound heterozygous status with a group of nucleotide alterations located at the 3′ end intron 4 and 5′ end exon 5 corresponding to the splice site acceptor region. Molecular studies continued in order to exclude the possibility of a nonclassical 21-OHD form. The group of three nucleotide changes was demonstrated to be a normal variant since they failed to interfere with the normal splicing process upon minigene studies.52813881392White, P.C., Speiser, P.W., Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (2000) Endocr Rev, 21, pp. 245-291Riepe, F.G., Sippell, W.G., Recent advances in diagnosis, treatment, and outcome of congenital adrenal hyperplasia due to 21-hydroxylase deficiency (2007) Rev Endocr Metab Disord, 8 (4), pp. 349-363New, M., Lorenzen, F., Lerner, A.J., Kohn, B., Oberfield, S.E., Pollack, M.S., Genotyping steroid 21-hydroxylase deficiency: Hormonal reference data (1983) J Clin Endocrinol Metab, 57, pp. 320-326Azziz, R., Hincapie, L.A., Knochenhauer, E.S., Dewailly, D., Fox, L., Boots, L.R., Screening for 21-hydroxylase-deficient nonclassic adrenal hyperplasia among hyperandrogenic women (1999) Fertil Steril, 72, pp. 915-925Bachega, T.A., Brenlha, E.M., Billerbeck, A.E., Marcondes, J.A., Madureira, G., Arnhold, I.J., Mendonca, B.B., Variable ACTH-stimulated 17-hydroxyprogesterone values in 21-hydroxylase deficiency carriers are not related to the different CYP21 gene mutations (2002) J Clin Endocrinol Metab, 87 (2), pp. 786-790Pang, S., Hotchkiss, J., Drash, A.L., Levine, L.S., New, M., Microfilter paper method for 17-hydroxyprogesterone radioimmunoassay: Its application for rapid screening for congenital adrenal hyperplasia (1977) J Clin Endocrinol Metab, 45, pp. 1003-1008Valentino, R., Tommaselli, A.P., Rossi, R., Lombardi, G., Varrone, S., A pilot study for neonatal screening of congenital adrenal hyperplasia due to 21-hydroxylase and 11-hydroxylase deficiency in Campania region (1990) J Endocrinol lnvest, 13, pp. 221-225Janzen, N., Peter, M., Sander, S., Steuerwald, U., Terhardt, M., Holtkamp, U., Sander, J., Newborn screening for congenital adrenal hyperplasia: Additional steroid profile using liquid chromatography-tandem mass spectrometry (2007) J Clin Endocrinol Metab, 92 (7), pp. 2581-2589Pang, S., Murphey, W., Levine, L.S., Lorenzen, F., Levy, D., Lerner, A.J., Rondanini, G.F., New, M., A pilot newborn screening for congenital adrenal hyperplasia in Alaska (1982) J Clin Endocrinol Metab, 55, pp. 413-420Nordenström, A., Wedell, A., Hagenfeldt, L., Marcus, C., Larsson, A., Neonatal screening for congenital adrenal hyperplasia: 17-hydroxyprogesterone levels and CYP21 genotypes in preterm infants (2001) Pediatrics, 108 (4), pp. E68Cardoso, C.B., Fonseca, A.A., Oliveira Mde, F., Pereira, B.B., Guimarães, M.M., Congenital adrenal hyperplasia newborn screening: Rio de Janeiro experience. Arq Bras Endocrinol (2005) Metabol, 49 (1), pp. 112-119Silveira, EL, D.S., Bachega, T.A., van der, Linden Nader, I., Gross, J.L., Elnecave, R.H., The actual incidence of congenital adrenal hyperplasia in Brazil may not be as high as inferred-an estimate based on a public neonatal screening program in the state of Goiás (2008) J Pediatr Endocrinol Metab, 21 (5), pp. 455-460Sambrook, J., Fritsch, E.F., Maniatis, T.E., (1989) Molecular Cloning, a Laboratory Manual, , New York: Cold Spring HarborAraujo, M., Sanches, M.R., Suzuki, L.A., Guerra-Jr, G., Farah, S.B., De Mello, M.P., Molecular analysis of CYP21 and C4 genes in Brazilian families with the classical form of steroid 21-hydroxylase deficiency (1996) Braz J Med Biol Res, 29, pp. 1-13Wilson, R.C., Wei, J.Q., Cheng, K.C., Mercado, A.B., New, M., Rapid deoxyribonucleic acid analysis by allele-specific polymerase chain reaction for detection of mutations in the steroid 21-hydroxylase gene (1995) J Clin Endocrinol Metab, 80 (5), pp. 1635-1640Lau, I.F., Soardi, F.C., Lemos-Marini, S.H., Guerra-Jr, G., Baptista, M.T., De Mello, M.P., H28+C insertion in the CYP21 gene: A novel frameshift mutation in Brazilian patient with the classical form of 21-hydroxylase deficiency (2001) J Clin Endocrinol Metab, 86, pp. 5877-5880Higashi, Y., Yoshioka, H., Yamane, M., Gotoh, O., Fujii-Kuriyama, Y., Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: A pseudogene and a genuine gene (1986) Proc Natl Acad Sci USA, 83, pp. 2841-2845Wilson, R.C., Nimkarn, S., Dumic, M., Obeid, J., Azar, M.R., Najmabadi, H., Ethnic-specific distribution of mutations in 716 patients with congenital adrenal hyperplasia owing to 21-hydroxylase deficiency (2007) Mol Genet Metab, 90 (4), pp. 414-421Tusie-Luna, M.T., Traktman, P., White, P.C., Determination of functional effects of mutations in the steroid 21-hydroxylase gene (CYP21) using recombinant vaccinia virus (1990) J Biol Chem, 265 (34), pp. 20916-20922Higashi, Y., Hiromasa, T., Tanae, A., Miki, T., Nakura, J., Kondo, T., Effects of individual mutations in the P-450(C21) pseudogene on the P-450(C21) activity and their distribution in the patient genomes of congenital steroid 21-hydroxylase deficiency (1991) J Biochem, 109 (4), pp. 638-644Bachega, T.A., Billerbeck, A.E., Madureira, G., Marcondes, J.A., Longui, C.A., Leite, M.V., Molecular genotyping in Brazilian patients with the classical and nonclassical forms of 21-hydroxylase deficiency (1998) J Clin Endocrinol Metab, 83 (12), pp. 4416-441

Avaliação de um modelo de passo invariante na predição da estrutura de um povoamento de Eucalyptus sp. Evaluation of a step invariant model for the prediction of eucalyptus stand structure

O objetivo deste estudo foi avaliar o modelo de distribuição diamétrica de passo invariante proposto por Guimarães (1994) na projeção da produção de um povoamento de Eucalyptus sp., simulando as alterações nas estruturas horizontal e vertical ao longo do tempo. Utilizaram-se dados da primeira rotação de povoamentos de eucalipto híbrido estaca (Eucalyptus grandis x Eucalyptus urophylla), plantados no espaçamento 3,0 x 2,0 m, localizados na região noroeste do Estado da Bahia, provenientes de medições anuais com idade de medição variando entre 25 e 89 meses. Para realizar as prognoses, foram empregados percentis tomados a 50 e 75% da distribuição diamétrica e as alturas correspondentes aos diâmetros nessas posições. Verificou-se que o modelo de projeção é factível e pode ser utilizado com eficiência, já que ocorreram tendências semelhantes entre os volumes prognosticados e os observados nas parcelas. Além disso, devido à sua simplicidade e à compatibilidade dos resultados, recomenda-se a sua utilização na projeção do crescimento e produção de Eucalyptus sp.<br>This study was carried out to evaluate the step-invariant diametric distribution model, proposed by Guimarães (1994), for the prediction of a Eucalyptus stand production, simulating the alterations in the horizontal and vertical structures with time. Data were taken from annual measurements, with measurement age between 25 and 89 months, of the first rotation of hybrid eucalyptus stands (Eucalyptus grandis x Eucalyptus urophylla), plant spacing of 3.0 x 2.0 m, located in the northeast region of State of Bahia. To perform prognoses percentiles were taken at 50 and 75% of the diametric distribution, and the heights corresponding to the diameters in these positions. The prediction model was proved to be feasible for efficient use, since there were similar tendencies between the forecasted and the observed volumes in the plots. Besides, its use in growth and production prediction of Eucalyptus sp. studies is recommended for its simplicity and result compatibility