Battle of the Attack Detection Algorithms:Disclosing cyber attacks on water distribution networks

The BATtle of the Attack Detection ALgorithms (BATADAL) is the most recent competition on planning and management of water networks undertaken within the Water Distribution Systems Analysis Symposium. The goal of the battle was to compare the performance of algorithms for the detection of cyber-physical attacks, whose frequency increased in the past few years along with the adoption of smart water technologies. The design challenge was set for C-Town network, a real-world, medium-sized water distribution system operated through Programmable Logic Controllers and a Supervisory Control And Data Acquisition (SCADA) system. Participants were provided with datasets containing (simulated) SCADA observations, and challenged with the design of an attack detection algorithm. The effectiveness of all submitted algorithms was evaluated in terms of time-to-detection and classification accuracy. Seven teams participated in the battle and proposed a variety of successful approaches leveraging data analysis, model-based detection mechanisms, and rule checking. Results were presented at the Water Distribution Systems Analysis Symposium (World Environmental & Water Resources Congress), in Sacramento, on May 21-25, 2017. This paper summarizes the BATADAL problem, proposed algorithms, results, and future research directions

Flexible Pores of a Metal Oxide-Based Capsule Permit Entry of Comparatively Larger Organic Guests

Ziv A, Grego A, Kopilevich S, et al. Flexible Pores of a Metal Oxide-Based Capsule Permit Entry of Comparatively Larger Organic Guests. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2009;131(18):6380-6382.In zeolites and other rigid solid-state oxides, substrates whose sizes exceed the pore dimensions of the material are rigorously excluded. Now, using a porous 3 nm diameter capsule-like oxomolybdate complex [{(Mo6O21)-O-VI(H2O)(6)}(12){((Mo2O4)-O-V)(30)(OAc)(21)(H2O)(18})](33-) as a water-soluble analogue of solid-state oxides (e.g., as a soluble analogue of 3 A molecular sieves), we show that carboxylates (RCO2-) can negotiate passage through flexible Mo9O9 pores in the surface of the capsule and that the rates follow the general trend R = 1 degrees >> 2 degrees > 3 degrees >> phenyl (no reaction). Surprisingly, the branched alkanes (R = iso-Pr and tert-Bu) enter the capsule even though they are larger than the crystallographic dimensions of the Mo9O9, pores. Four independent lines of spectroscopic and kinetic evidence demonstrate that these organic guests enter the interior of the capsule through its Mo9O9 apertures and that no irreversible changes in the metal oxide framework are involved. This unexpected phenomenon likely reflects the greater flexibility of molecular versus solid-state structures and represents a sharp departure from traditional models for diffusion through porous solid-state (rigid) oxides

Battle of the Attack Detection Algorithms:Disclosing cyber attacks on water distribution networks

The BATtle of the Attack Detection ALgorithms (BATADAL) is the most recent competition on planning and management of water networks undertaken within the Water Distribution Systems Analysis Symposium. The goal of the battle was to compare the performance of algorithms for the detection of cyber-physical attacks, whose frequency has increased in the last few years along with the adoption of smart water technologies. The design challenge was set for the C-Town network, a real-world, medium-sized water distribution system operated through programmable logic controllers and a supervisory control and data acquisition (SCADA) system. Participants were provided with data sets containing (simulated) SCADA observations, and challenged to design an attack detection algorithm. The effectiveness of all submitted algorithms was evaluated in terms of time-to-detection and classification accuracy. Seven teams participated in the battle and proposed a variety of successful approaches leveraging data analysis, model-based detection mechanisms, and rule checking. Results were presented at the Water Distribution Systems Analysis Symposium (World Environmental and Water Resources Congress) in Sacramento, California on May 21-25, 2017. This paper summarizes the BATADAL problem, proposed algorithms, results, and future research directions.</p

Ranolazine in High-Risk Patients With Implanted Cardioverter-Defibrillators: The RAID Trial

BACKGROUND: Ventricular tachycardia (VT) and ventricular fibrillation (VF) remain a challenging problem in patients with implantable cardioverter-defibrillators (ICDs). OBJECTIVES: This study aimed to determine whether ranolazine administration decreases the likelihood of VT, VF, or death in patients with an ICD. METHODS: This was double-blind, placebo-controlled clinical trial in which high-risk ICD patients with ischemic or nonischemic cardiomyopathy were randomized to 1,000 mg ranolazine twice a day or placebo. The primary endpoint was VT or VF requiring appropriate ICD therapy or death, whichever occurred first. Pre-specified secondary endpoints included ICD shock for VT, VF, or death and recurrent VT or VF requiring ICD therapy. RESULTS: Among 1,012 ICD patients (510 randomized to ranolazine and 502 to placebo) the mean age was 64 ± 10 years and 18% were women. During 28 ± 16 months of follow-up there were 372 (37%) patients with primary endpoint, 270 (27%) patients with VT or VF, and 148 (15%) deaths. The blinded study drug was discontinued in 199 (39.6%) patients receiving placebo and in 253 (49.6%) patients receiving ranolazine (p = 0.001). The hazard ratio for ranolazine versus placebo was 0.84 (95% confidence interval: 0.67 to 1.05; p = 0.117) for VT, VF, or death. In a pre-specified secondary analysis, patients randomized to ranolazine had a marginally significant lower risk of ICD therapies for recurrent VT or VF (hazard ratio: 0.70; 95% confidence interval: 0.51 to 0.96; p = 0.028). There were no other significant treatment effects in other pre-specified secondary analyses, which included individual components of the primary endpoint, inappropriate shocks, cardiac hospitalizations, and quality of life. CONCLUSIONS: In high-risk ICD patients, treatment with ranolazine did not significantly reduce the incidence of the first VT or VF, or death. However, the study was underpowered to detect a difference in the primary endpoint. In prespecified secondary endpoint analyses, ranolazine administration was associated with a significant reduction in recurrent VT or VF requiring ICD therapy without evidence for increased mortality. (Ranolazine Implantable Cardioverter-Defibrillator Trial [RAID]; NCT01215253)