Ecotourism for Community Empowerment and Social Inclusion: The Case of Abindu Sacred site in Kisumu County, Kenya

Ecotourism, which is currently the fastest growing form of global tourism in the world, is more prevalent today than ever before. Communities that once had very little industry and misguided management systems have now been able to flourish with the employment of local people. By involving the local people in these programs and when a direct stimulus is returned to the community, rather than having the profits sent elsewhere, programs have been proven to be much more successful. When discussing ecotourism, it is also important to realize that these programs are not always beneficial to the local communities and many ecotourism ventures are controlled by outside operators. A useful way to discern responsible community-based ecotourism is to approach it from a development perspective, which considers social, environmental and economic goals, and questions how ecotourism can meet the needs of the host community in terms of improved living standards both in the short and long term. This perspective differs somewhat from those approaching ecotourism predominantly from an environmental perspective.The achievement of sustainable tourism development through community based ecotourism initiatives, require the building of community capacities to understand the importance of the resources they own. Most communities are unaware of the potential their cultural and natural natural resources offer. This study will focus on the potential of an ecotourism site, namely, Abindu in Nyahera, in Kisumu County, where there is possibility of organizing the community to run ecotourism ventures.The general objective of the study was to ascertain livelihood enhancement opportunities brought in the wake of ecotourism development in host communities, whilst the specific objectives are to: assess the likely identify key stakeholders in the ecotourism site; assess the level of female empowerment in the development of ecotourism in the community; examine the impacts of ecotourism ventures in the community. The Study examined this community in terms of an empowerment framework as a suitable mechanism for aiding analysis of the social, economic, psychological and political impacts of ecotourism on local communities.The study used qualitative methods to collect the data, namely,participant observation, key informant Interviews, and focused group discussions. Keywords: Ecotourism, Community based Ecotourism, Empowerment, Abindu, Kisumu

Community Perception of Cultural Identity of Heritage Sites for Determining Local Participation in their Management and Conservation: The Case of Thimlich Ohinga and Seme-Kaila in Kenya

The study investigated the significance of cultural identity of prehistoric settlements in establishing community participation in their conservation and management for ecotourism promotion. This was accomplished using both qualitative and quantitative methods of data collection and analyzed using descriptive and inferential statistics, as well as, content analysis. The research employed value theory to interpret the data and provide clarity of the research findings. The study concluded that there is a significant relationship between community perception of cultural identity of the sites and community participation in their conservation and management for ecotourism promotion. High level of community perception of cultural identity of Thimlich Ohinga indicates high community participation in the conservation and management of the site. Low level of community perception of cultural identity of Seme-Kaila shows low community participation in the conservation and management of the site. KEY WORDS: Cultural identity, community perception, community participation, management, conservation, heritage site

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

Genome-wide association and fine-mapping studies in 14 autoimmune diseases (AID) have implicated more than 250 loci in one or more of these diseases. As more than 90% of AID-associated SNPs are intergenic or intronic, pinpointing the causal genes is challenging. We performed a systematic analysis to link 460 SNPs that are associated with 14 AID to causal genes using transcriptomic data from 629 blood samples. We were able to link 71 (39%) of the AID-SNPs to two or more nearby genes, providing evidence that for part of the AID loci multiple causal genes exist. While 54 of the AID loci are shared by one or more AID, 17% of them do not share candidate causal genes. In addition to finding novel genes such as ULK3, we also implicate novel disease mechanisms and pathways like autophagy in celiac disease pathogenesis. Furthermore, 42 of the AID SNPs specifically affected the expression of 53 non-coding RNA genes. To further understand how the non-coding genome contributes to AID, the SNPs were linked to functional regulatory elements, which suggest a model where AID genes are regulated by network of chromatin looping/non-coding RNAs interactions. The looping model also explains how a causal candidate gene is not necessarily the gene closest to the AID SNP, which was the case in nearly 50% of cases

Age at first birth in women is genetically associated with increased risk of schizophrenia

Prof. Paunio on PGC:n jäsenPrevious studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic association between schizophrenia and age at first birth in women (AFB). Here, we use independent data from the UK Biobank (N = 38,892) to replicate the finding of an association between predicted genetic risk of schizophrenia and AFB in women, and to estimate the genetic correlation between schizophrenia and AFB in women stratified into younger and older groups. We find evidence for an association between predicted genetic risk of schizophrenia and AFB in women (P-value = 1.12E-05), and we show genetic heterogeneity between younger and older AFB groups (P-value = 3.45E-03). The genetic correlation between schizophrenia and AFB in the younger AFB group is -0.16 (SE = 0.04) while that between schizophrenia and AFB in the older AFB group is 0.14 (SE = 0.08). Our results suggest that early, and perhaps also late, age at first birth in women is associated with increased genetic risk for schizophrenia in the UK Biobank sample. These findings contribute new insights into factors contributing to the complex bio-social risk architecture underpinning the association between parental age and offspring mental health.Peer reviewe

Highly-parallelized simulation of a pixelated LArTPC on a GPU

The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 10^3 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype

The DUNE far detector vertical drift technology. Technical design report

DUNE is an international experiment dedicated to addressing some of the questions at the forefront of particle physics and astrophysics, including the mystifying preponderance of matter over antimatter in the early universe. The dual-site experiment will employ an intense neutrino beam focused on a near and a far detector as it aims to determine the neutrino mass hierarchy and to make high-precision measurements of the PMNS matrix parameters, including the CP-violating phase. It will also stand ready to observe supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector implements liquid argon time-projection chamber (LArTPC) technology, and combines the many tens-of-kiloton fiducial mass necessary for rare event searches with the sub-centimeter spatial resolution required to image those events with high precision. The addition of a photon detection system enhances physics capabilities for all DUNE physics drivers and opens prospects for further physics explorations. Given its size, the far detector will be implemented as a set of modules, with LArTPC designs that differ from one another as newer technologies arise. In the vertical drift LArTPC design, a horizontal cathode bisects the detector, creating two stacked drift volumes in which ionization charges drift towards anodes at either the top or bottom. The anodes are composed of perforated PCB layers with conductive strips, enabling reconstruction in 3D. Light-trap-style photon detection modules are placed both on the cryostat's side walls and on the central cathode where they are optically powered. This Technical Design Report describes in detail the technical implementations of each subsystem of this LArTPC that, together with the other far detector modules and the near detector, will enable DUNE to achieve its physics goals