Smart Factory Testbed Setup – Initial Results

The main objective of the SmartFactory-KL Use Case follows the general objectives of WP6, to prove and validate the MAS4AI approach in industrial test beds. The modular Industrie 4.0 testbed of the Technology Initiative SmartFactory KL provides the possibility to build up, test and deploy the MAS approach combined with the prototypical development and implementation of defined agents with their requirements from WP 1. The SmartFactory KL testbed provides the basis for the first functional prototype which is based on the MAS4AI architecture concept and consist of a modular production environment and the integration of message-based middleware solutions like OPC UA or the BaSyx-Middleware. The usage of several software components like discovery and registry services, which are essential in the testbed architecture, as well as the agent development and their configuration and execution is also considered in the context of the MAS deployment. The development of the first prototypical MAS4AI implementation, which is documented in this document, follows several iterations. With each iteration, new components and features have been considered for interacting in the used MAS framework. The developments in the MAS framework Janus SARL, which is applied to the Smart Factory testbed to meet the requirements along predefined agent patterns, and the connection to physical hardware component for control purpose are presented as results of the first prototypical implementation

Drotrecogin alfa (Activated) in adults with septic shock

There have been conflicting reports on the efficacy of recombinant human activated protein C, or drotrecogin alfa (activated) (DrotAA), for the treatment of patients with septic shock.In this randomized, double-blind, placebo-controlled, multicenter trial, we assigned 1697 patients with infection, systemic inflammation, and shock who were receiving fluids and vasopressors above a threshold dose for 4 hours to receive either DrotAA (at a dose of 24 μg per kilogram of body weight per hour) or placebo for 96 hours. The primary outcome was death from any cause 28 days after randomization.At 28 days, 223 of 846 patients (26.4%) in the DrotAA group and 202 of 834 (24.2%) in the placebo group had died (relative risk in the DrotAA group, 1.09; 95% confidence interval [CI], 0.92 to 1.28; P=0.31). At 90 days, 287 of 842 patients (34.1%) in the DrotAA group and 269 of 822 (32.7%) in the placebo group had died (relative risk, 1.04; 95% CI, 0.90 to 1.19; P=0.56). Among patients with severe protein C deficiency at baseline, 98 of 342 (28.7%) in the DrotAA group had died at 28 days, as compared with 102 of 331 (30.8%) in the placebo group (risk ratio, 0.93; 95% CI, 0.74 to 1.17; P=0.54). Similarly, rates of death at 28 and 90 days were not significantly different in other predefined subgroups, including patients at increased risk for death. Serious bleeding during the treatment period occurred in 10 patients in the DrotAA group and 8 in the placebo group (P=0.81).DrotAA did not significantly reduce mortality at 28 or 90 days, as compared with placebo, in patients with septic shock. (Funded by Eli Lilly; PROWESS-SHOCK ClinicalTrials.gov number, NCT00604214.)

An upper limit on the τ\tau neutrino mass from three- and five-prong tau decays

A bound on the tau neutrino mass is established using the data collected from 1991 to 1995 at Ecm = M(Z) with the ALEPH detector. Two separate limits are derived by fitting the distribution of visible energy vs invariant mass in tau+ -> pi+ pi+ pi- nu and tau+ -> pi+ pi+ pi- pi- pi+ (pi0) nu decays. The two results are combined to obtain a 95 % confidence level upper limit of 18.2 MeV/c^2 on the mass of the tau neutrino

Measurement of the W pair cross-section in e+ e- collisions at 172-GeV

The e+e−→W+W− cross section is measured in a data sample collected by ALEPH at a mean centre-of-mass energy of 172.09 GeV, corresponding to an integrated luminosity of 10.65 pb−1. Cross sections are given for the three topologies, fully leptonic, semi-leptonic and hadronic of a W-pair decay. Under the assumption that no other decay modes are present, the W-pair cross section is measured to be The existence of the triple gauge boson vertex of the Standard Model is clearly preferred by the data. The decay branching ratio of the W boson into hadrons is measured to be , allowing a determination of the CKM matrix element |Vcs|=0.98±0.14(stat.)±0.03(syst.)

KS0K^{0}_{S} production in τ\tau decays

From a sample of about 160k \mbox{Z}\!\!\to\!\!\tau^+\tau^- candidates collected with the ALEPH detector at LEP between 1991 and 1995, $\tau$ lepton decays involving $K^0_S\!\to\!\pi^+\pi^-$ are studied. The $K^0_SK^0_L$ associated production in $\tau$ decays is also investigated. The branching ratios are measured for the inclusive decay $B(\tau^-\!\!\to\!\!K^0_SX^-\nu_\tau)=(9.70\!\pm\!0.58\!\pm\!0.62)\ times10^{-3}$ , where $X^-$ can be anything, and for the exclusive decays \begin{center} \begin{tabular}{rcl} $B(\tau^-\!\!\to\!\!\overline{K}^0\pi^-\nu_\tau)$&=&$(8.55\!\pm\!1. 17\! \pm\!0.66)\times10^{-3}$,\\ $B(\tau^-\!\!\to\!\!\overline{K}^0\pi ^-\pi^0\nu_\tau)$&=&$(2.94\!\pm\! 0.73\!\pm\!0.37)\times10^{-3}$, \\ $B(\tau^-\!\!\to\!\!\overline{K} ^0K^-\nu_\tau)$&=&$(1.58\!\pm\!0.42\!\pm\! 0.17)\times10^{-3}$, \\ $B(\tau^-\!\!\to\!\!\overline{K}^0K^-\pi^0\nu_\tau)$&=&$(1.52\!\pm\ !0.76\! \pm\!0.21)\times10^{-3}$. \\ \end{tabular} \end{center} The decays $\tau^-\!\!\to\!\!K^0_SK^0_L\pi^-\nu_\tau$ is studied for the first time, giving a branching ratio \begin{center} \begin{tabular}{rcl} $B(\tau^-\!\!\to\!\!K^0_SK^0_L\pi^-\nu_\tau)$&=&$(1.01\!\pm\!0.23\!\pm\!0.13)\times10^{-3}.$ \end{tabular} \end{center} The channels $\tau^-~\!\!\!\to\!\!\!~K^0_SK^0_S\pi^-\nu_\tau~$, $\tau^-~\!\!\!\to\!\!\!~K^0_SK^0_S\pi^-\pi^0\nu_\tau~$, $\tau^-~\!\!\!\to\!\!\!~K^0_SK^0_L\pi^-\pi^0\nu_\tau~$, $\tau^-~\!\!\!\to\!\!\!~\overline{K}^0\pi^-\pi^0\pi^0\nu_\tau$, $\tau^-~\!\!\!\to\!\!\!~K^0K^-\pi^0\pi^0\nu_\tau$ and $\tau^-~\!\!\!\to\!\!\!~K^0h^+h^-h^-\nu_\tau$ are also investigated. In addition, mass spectra in the $K^0_Sh^-$ and $K^0_Sh^-\pi^0$ final states are analysed to provide information on the intermediate states produced in the decays

Determination of |V(ub)| from the measurement of the inclusive charmless semileptonic branching ratio of b hadrons

From a study of the kinematic properties of the final state produced in the semileptonic decays b→Xℓνℓ , the inclusive charmless semileptonic branching ratio of b hadrons is measured. With a sample of 3.6 million hadronic Z decays recorded between 1992 and 1995 with the ALEPH detector at LEP, the value Br(b→Xuℓνℓ) is determined to be (1.73±0.55stat±0.55syst)×10−3 , where Xu represents any charmless hadronic state and b is a mixture of b hadrons weighted by their production rates. This measurement yields the result |Vub|2=(18.68±5.94stat±5.94syst±1.45HQE)×10−6, where the last error comes from the conversion of the branching ratio to the CKM matrix element squared

Measurement of the B baryon lifetime and branching fractions in Z decays

Using approximately 4 million hadronic Z decays recorded with the aleph detector from 1991 through 1995, the lifetime of the b baryon is measured with three independent methods. From the impact parameter distribution of candidate leptons in 1063 events with Λℓ− combinations, the average b baryon lifetime is measured to be 1.20±0.08±0.06 ps. From a sample of 193 fully reconstructed Λ+c candidates correlated with a lepton and a sample of 46 Λℓ+ℓ− combinations, the Λb lifetime is measured to be 1.21±0.11 ps. The product branching fractions to these final states are Br(b→Λb⋅BR(Λb→Λℓ−ν¯X)=0.326±0.016±0.039 % for the first sample and Br(b→Λb⋅BR(Λb→Λ+cℓ−ν¯X)=0.86±0.07±0.14 % for the second and third samples combined

Measurement of the spectral functions of vector current hadronic tau decays

A measurement of the spectral functions of non-strange tau vector current final states is presented, using 124,358 tau pairs recorded by the ALEPH detector at LEP during the years 1991 to 1994. The spectral functions of the dominant two- and four-pion tau decay channels are compared to published results of e+e- annihilation experiments via isospin rotation. A combined fit of the pion form factor from tau decays and e+e- data is performed using different parametrizations. The mass and the width of the charged and the neutral rho(770) are separately determined in order to extract possible isospin violating effects. The mass and width differences are measured to be M(rho^+/-(770)) - M(rho^0(770)) = (0.0 +/- 1.0) MeV/c^2 and Gamma(rho^+/-(770)) - Gamma(rho^0(770)) = (0.1 +/- 1.9) MeV/c^2