102 research outputs found
Air Displacement Plethysmography and Resistance Exercise
Purpose: The purpose of this study was to examine the effect of resistance exercise (RE) on body composition using air-displacement plethysmography (ADP) within 2 hours of completing RE. Methods: Thirteen university students (9 males and 4 females; 18.8±0.5 yrs; mean ± SD) volunteered for this study. The RE program (55.4±8.7 min) consisted of a combination of upper- and lower-body extremity exercises and abdominal exercises for a total of nine different exercises. Relative body fat (BF) was assessed (1.76+0.4 hr) using ADP before and after the RE along with skinfold (SF) measures, body mass (BM) and respiratory quotient. Results: Statistically significant reductions in pre-post RE relative BF measurements (p=0.036) were observed using ADP along with statistically significant reductions in body volume (BV) (p=0.005), body mass (BM) (p=0.038) and fat mass (FM) (p=0.020). The mean intraclass correlation coefficients (ICC) for these variables was 0.99. No significant pre-post differences in fat-free mass (FFM), body mass index (BMI) or skinfold (SF) values were reported. Conclusions: This study demonstrates the potential adverse effects of assessing relative BF within 2 hours after RE. Significant differences in pre-post relative BF were supported by significant reductions in BV, BM, and FM. The results of this study support the manufacturer guidelines using ADP and RE restriction prior to body composition assessment
Exercising in the Fasted State Reduced 24-Hour Energy Intake in Active Male Adults
The effect of fasting prior to morning exercise on 24-hour energy intake was examined using a randomized, counterbalanced design. Participants (12 active, white males, 20.8±3.0 years old, VO2max: ââ59.1±5.7âmL/kg/min) fasted (NoBK) or received breakfast (BK) and then ran for 60 minutes at 60%ââVO2max. All food was weighed and measured for 24 hours. Measures of blood glucose and hunger were collected at 5 time points. Respiratory quotient (RQ) was measured during exercise. Generalized linear mixed models and paired sample t-tests examined differences between the conditions. Total 24-hour (BK: 19172±4542âkJ versus NoBK: 15312±4513âkJ; p<0.001) and evening (BK: 12265±4278âkJ versus NoBK: 10833±4065; p=0.039) energy intake and RQ (BK: 0.90±0.03 versus NoBK: 0.86±0.03; p<0.001) were significantly higher in BK than NoBK. Blood glucose was significantly higher in BK than NoBK before exercise (5.2±0.7 versus 4.5±0.6âmmol/L; p=0.025). Hunger was significantly lower for BK than NoBK before exercise, after exercise, and before lunch. Blood glucose and hunger were not associated with energy intake. Fasting before morning exercise decreased 24-hour energy intake and increased fat oxidation during exercise. Completing exercise in the morning in the fasted state may have implications for weight management
Global Chemical Transport on Hot Jupiters: Insights from 2D VULCAN photochemical model
The atmospheric dynamics of tidally-locked hot Jupiters is dominated by the
equatorial winds. Understanding the interaction between global circulation and
chemistry is crucial in atmospheric studies and interpreting observations.
Two-dimensional (2D) photochemical transport models shed light on how the
atmospheric composition depends on circulation. In this paper, we introduce the
2D photochemical transport model, VULCAN 2D, which improves on the pseudo-2D
approaches by allowing for non-uniform zonal winds. We extensively validate our
VULCAN 2D with analytical solutions and benchmark comparisons. Applications to
HD 189733 b and HD 209458 b reveal distinct characteristics in horizontal
transport-dominated and vertical mixing-dominated regimes. Motivated by the
inferred carbon-rich atmosphere by Giacobbe et al. (2021), we find that HD
209458 b with super-solar carbon-to-oxygen ratio (C/O) exhibits pronounced C2H4
absorption on the morning limb but not on the evening limb, owing to horizontal
transport from the nightside. We discuss when a pseudo-2D approach is a valid
assumption and its inherent limitations. Finally, we demonstrate the effect of
horizontal transport in transmission observations and its impact on the
morning-evening limb asymmetry with synthetic spectra, highlighting the need to
consider global transport when interpreting exoplanet atmospheres.Comment: 18 pages, 20 figures, submitted to Ap
Exoplanet Biosignatures: Understanding Oxygen as a Biosignature in the Context of Its Environment
Here we review how environmental context can be used to interpret whether O2
is a biosignature in extrasolar planetary observations. This paper builds on
the overview of current biosignature research discussed in Schwieterman et al.
(2017), and provides an in-depth, interdisciplinary example of biosignature
identification and observation that serves as a basis for the development of
the general framework for biosignature assessment described in Catling et al.,
(2017). O2 is a potentially strong biosignature that was originally thought to
be an unambiguous indicator for life at high-abundance. We describe the
coevolution of life with the early Earth's environment, and how the interplay
of sources and sinks in the planetary environment may have resulted in
suppression of O2 release into the atmosphere for several billion years, a
false negative for biologically generated O2. False positives may also be
possible, with recent research showing potential mechanisms in exoplanet
environments that may generate relatively high abundances of atmospheric O2
without a biosphere being present. These studies suggest that planetary
characteristics that may enhance false negatives should be considered when
selecting targets for biosignature searches. Similarly our ability to interpret
O2 observed in an exoplanetary atmosphere is also crucially dependent on
environmental context to rule out false positive mechanisms. We describe future
photometric, spectroscopic and time-dependent observations of O2 and the
planetary environment that could increase our confidence that any observed O2
is a biosignature, and help discriminate it from potential false positives. By
observing and understanding O2 in its planetary context we can increase our
confidence in the remote detection of life, and provide a model for
biosignature development for other proposed biosignatures.Comment: 55 pages. The paper is the second in a series of 5 review manuscripts
of the NExSS Exoplanet Biosignatures Workshop. Community commenting is
solicited at https://nexss.info/groups/ebww
The Spectral Energy Distribution of Fermi bright blazars
(Abridged) We have conducted a detailed investigation of the broad-band
spectral properties of the \gamma-ray selected blazars of the Fermi LAT Bright
AGN Sample (LBAS). By combining our accurately estimated Fermi gamma-ray
spectra with Swift, radio, infra-red, optical and other hard X-ray/gamma-ray
data, collected within three months of the LBAS data taking period, we were
able to assemble high-quality and quasi-simultaneous Spectral Energy
Distributions (SED) for 48 LBAS blazars.The SED of these gamma-ray sources is
similar to that of blazars discovered at other wavelengths, clearly showing, in
the usual Log - Log F representation, the typical broad-band
spectral signatures normally attributed to a combination of low-energy
synchrotron radiation followed by inverse Compton emission of one or more
components. We have used these SEDs to characterize the peak intensity of both
the low and the high-energy components. The results have been used to derive
empirical relationships that estimate the position of the two peaks from the
broad-band colors (i.e. the radio to optical and optical to X-ray spectral
slopes) and from the gamma-ray spectral index. Our data show that the
synchrotron peak frequency is positioned between 10 and
10 Hz in broad-lined FSRQs and between and Hz in
featureless BL Lacertae objects.We find that the gamma-ray spectral slope is
strongly correlated with the synchrotron peak energy and with the X-ray
spectral index, as expected at first order in synchrotron - inverse Compton
scenarios. However, simple homogeneous, one-zone, Synchrotron Self Compton
(SSC) models cannot explain most of our SEDs, especially in the case of FSRQs
and low energy peaked (LBL) BL Lacs. (...)Comment: 85 pages, 38 figures, submitted to Ap
Feature extraction and selection for Arabic tweets authorship authentication
© 2017, Springer-Verlag Berlin Heidelberg. In tweet authentication, we are concerned with correctly attributing a tweet to its true author based on its textual content. The more general problem of authenticating long documents has been studied before and the most common approach relies on the intuitive idea that each author has a unique style that can be captured using stylometric features (SF). Inspired by the success of modern automatic document classification problem, some researchers followed the Bag-Of-Words (BOW) approach for authenticating long documents. In this work, we consider both approaches and their application on authenticating tweets, which represent additional challenges due to the limitation in their sizes. We focus on the Arabic language due to its importance and the scarcity of works related on it. We create different sets of features from both approaches and compare the performance of different classifiers using them. We experiment with various feature selection techniques in order to extract the most discriminating features. To the best of our knowledge, this is the first study of its kind to combine these different sets of features for authorship analysis of Arabic tweets. The results show that combining all the feature sets we compute yields the best results
Life Beyond the Solar System: Remotely Detectable Biosignatures
For the first time in human history, we will soon be able to apply to the scientific method to the question "Are We Alone?" The rapid advance of exoplanet discovery, planetary systems science, and telescope technology will soon allow scientists to search for life beyond our Solar System through direct observation of extrasolar planets. This endeavor will occur alongside searches for habitable environments and signs of life within our Solar System. While these searches are thematically related and will inform each other, they will require separate observational techniques. The search for life on exoplanets holds potential through the great diversity of worlds to be explored beyond our Solar System. However, there are also unique challenges related to the relatively limited data this search will obtain on any individual world
Transcriptomic and Epigenetic Regulation of Disuse Atrophy and the Return to Activity in Skeletal Muscle
Physical inactivity and disuse are major contributors to age-related muscle loss. Denervation of skeletal muscle has been previously used as a model with which to investigate muscle atrophy following disuse. Although gene regulatory networks that control skeletal muscle atrophy after denervation have been established, the transcriptome in response to the recovery of muscle after disuse and the associated epigenetic mechanisms that may function to modulate gene expression during skeletal muscle atrophy or recovery have yet to be investigated. We report that silencing the tibialis anterior muscle in rats with tetrodotoxin (TTX)âadministered to the common peroneal nerveâresulted in reductions in muscle mass of 7, 29, and 51% with corresponding reductions in muscle fiber cross-sectional area of 18, 42, and 69% after 3, 7, and 14 d of TTX, respectively. Of importance, 7 d of recovery, during which rodents resumed habitual physical activity, restored muscle mass from a reduction of 51% after 14 d TTX to a reduction of only 24% compared with sham control. Returning muscle mass to levels observed at 7 d TTX administration (29% reduction). Transcriptome-wide analysis demonstrated that 3714 genes were differentially expressed across all conditions at a significance of P †0.001 after disuse-induced atrophy. Of interest, after 7 d of recovery, the expression of genes that were most changed during TTX had returned to that of the sham control. The 20 most differentially expressed genes after microarray analysis were identified across all conditions and were cross-referenced with the most frequently occurring differentially expressed genes between conditions. This gene subset included myogenin (MyoG), Hdac4, Ampd3, Trim63 (MuRF1), and acetylcholine receptor subunit α1 (Chrna1). Transcript expression of these genes and Fboxo32 (MAFbx), because of its previously identified role in disuse atrophy together with Trim63 (MuRF1), were confirmed by real-time quantitative RT-PCR, and DNA methylation of their promoter regions was analyzed by PCR and pyrosequencing. MyoG, Trim63 (MuRF1), Fbxo32 (MAFbx), and Chrna1 demonstrated significantly decreased DNA methylation at key time points after disuse-induced atrophy that corresponded with significantly increased gene expression. Of importance, after TTX cessation and 7 d of recovery, there was a marked increase in the DNA methylation profiles of Trim63 (MuRF1) and Chrna1 back to control levels. This also corresponded with the return of gene expression in the recovery group back to baseline expression observed in sham-operated controls. To our knowledge, this is the first study to demonstrate that skeletal muscle atrophy in response to disuse is accompanied by dynamic epigenetic modifications that are associated with alterations in gene expression, and that these epigenetic modifications and gene expression profiles are reversible after skeletal muscle returns to normal activity
Quantifying the Influence of Jupiter on the Earth's Orbital Cycles
A wealth of Earth-sized exoplanets will be discovered in the coming years,
proving a large pool of candidates from which the targets for the search for
life beyond the Solar system will be chosen. The target selection process will
require the leveraging of all available information in order to maximise the
robustness of the target list and make the most productive use of follow-up
resources. Here, we present the results of a suite of -body simulations that
demonstrate the degree to which the orbital architecture of the Solar system
impacts the variability of Earth's orbital elements. By varying the orbit of
Jupiter and keeping the initial orbits of the other planets constant, we
demonstrate how subtle changes in Solar system architecture could alter the
Earth's orbital evolution -- a key factor in the Milankovitch cycles that alter
the amount and distribution of solar insolation, thereby driving periodic
climate change on our planet. The amplitudes and frequencies of Earth's modern
orbital cycles fall in the middle of the range seen in our runs for all
parameters considered -- neither unusually fast nor slow, nor large nor small.
This finding runs counter to the `Rare Earth' hypothesis, which suggests that
conditions on Earth are so unusual that life elsewhere is essentially
impossible. Our results highlight how dynamical simulations of newly discovered
exoplanetary systems could be used as an additional means to assess the
potential targets of biosignature searches, and thereby help focus the search
for life to the most promising targets.Comment: 19 pages; 11 figures; accepted for publication in the Astronomical
Journal Version 2 - incorporates typo corrections and minor changes noted at
the proofing stage, after acceptanc
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