MALT-45: a 7 mm survey of the southern Galaxy - I. Techniques and spectral line data

We present the first results from the MALT-45 (Millimetre Astronomer's Legacy Team-45 GHz) Galactic Plane survey. We have observed 5 square degrees (l = 330°–335°, b = ±0 ∘ . 5) for spectral lines in the 7 mm band (42–44 and 48–49 GHz), including CS (1–0), class I CH3OH masers in the 7(0,7)–6(1,6) A+ transition and SiO (1–0) v = 0, 1, 2, 3. MALT-45 is the first unbiased, large-scale, sensitive spectral line survey in this frequency range. In this paper, we present data from the survey as well as a few intriguing results; rigorous analyses of these science cases are reserved for future publications. Across the survey region, we detected 77 class I CH3OH masers, of which 58 are new detections, along with many sites of thermal and maser SiO emission and thermal CS. We found that 35 class I CH3OH masers were associated with the published locations of class II CH3OH, H2O and OH masers but 42 have no known masers within 60 arcsec. We compared the MALT-45 CS with NH3 (1,1) to reveal regions of CS depletion and high opacity, as well as evolved star-forming regions with a high ratio of CS to NH3. All SiO masers are new detections, and appear to be associated with evolved stars from the Spitzer Galactic Legacy Infrared Mid-Plane Survey Extraordinaire (GLIMPSE). Generally, within SiO regions of multiple vibrational modes, the intensity decreases as v = 1, 2, 3, but there are a few exceptions where v = 2 is stronger than v = 1

Bivalves as indicators of environmental variation and potential anthropogenic impacts in the southern Barents Sea

Author Posting. © Elsevier B.V., 2009. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Marine Pollution Bulletin 59 (2009): 193-206, doi:10.1016/j.marpolbul.2009.02.022.Identifying patterns and drivers of natural variability in populations is necessary to gauge potential effects of climatic change and the expected increases in commercial activities in the Arctic on communities and ecosystems. We analyzed growth rates and shell geochemistry of the circumpolar Greenland smooth cockle, Serripes groenlandicus, from the southern Barents Sea over almost 70 years between 1882 and 1968. The datasets were calibrated via annually-deposited growth lines, and growth, stable isotope (δ18O, δ13C), and trace elemental (Mg, Sr, Ba, Mn) patterns were linked to environmental variations on weekly to decadal scales. Standardized growth indices revealed an oscillatory growth pattern with a multi-year periodicity, which was inversely related to the North Atlantic Oscillation Index (NAO), and positively related to local river discharge. Up to 60% of the annual variability in the Ba/Ca could be explained by variations in river discharge at the site closest to the rivers, but the relationship disappeared at a more distant location. Patterns of δ18O, δ13C, and Sr/Ca together provide evidence that bivalve growth ceases at elevated temperatures during the fall and recommences at the coldest temperatures in the early spring, with the implication that food, rather than temperature, is the primary driver of bivalve growth. The multi-proxy approach of combining the annually integrated information from the growth results and higher resolution geochemical results yielded a robust interpretation of biophysical coupling in the region over temporal and spatial scales. We thus demonstrate that sclerochronological proxies can be useful retrospective analytical tools for establishing a baseline of ecosystem variability in assessing potential combined impacts of climatic change and increasing commercial activities on Arctic communities.We gratefully acknowledge past financial support from Norsk Hydro, and continuing financial support from StatoilHydro, the Norwegian Research Council, and the Howard Hughes Medical Institute through Bates College. This publication was made possible, in part, by NIH Grant Number P20 RR-016463 from the INBRE Program of the National Center for Research Resources

The Evolutionary Map of the Universe Pilot Survey

We present the data and initial results from the first pilot survey of the Evolutionary Map of the Universe (EMU), observed at 944 MHz with the Australian Square Kilometre Array Pathfinder (ASKAP) telescope. The survey covers 270 deg2 of an area covered by the Dark Energy Survey, reaching a depth of 25–30 μJy beam−1 rms at a spatial resolution of ∼11–18 arcsec, resulting in a catalogue of ∼220 000 sources, of which ∼180 000 are single-component sources. Here we present the catalogue of single-component sources, together with (where available) optical and infrared cross-identifications, classifications, and redshifts. This survey explores a new region of parameter space compared to previous surveys. Specifically, the EMU Pilot Survey has a high density of sources, and also a high sensitivity to low surface brightness emission. These properties result in the detection of types of sources that were rarely seen in or absent from previous surveys. We present some of these new results here

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

Logic Databases and the Meaning of Change

This technical report contains preliminary proceedings of the seminar "Logical Databases and the Meaning of Change" held in Dagstuhl, Germany, September 23--27, 1996. 1 1 This technical report and other technical reports in this series can be obtained at http://www.csd.uu.se/reports.html or at ftp.csd.uu.se in the directory pub/papers/reports. Some reports can be updated, check one of these addresses for the latest version. i Contents Hendrik Decker. View updating by abduction and integrity maintenance 1 Laurence Cholvy. Adding information by taking topics into account 6 Raymond Reiter. A formal and computational account of database transactions 12 Michael Leuschel and Danny De Schreye. Specialised Integrity Checking by Combining Conjunctive Partial Deduction and Abstract Interpretation 14 Ernest Teniente and Toni Urp'i. Classification and Specification of Update Problems 16 Carlo Zaniolo. A Minimalist's Approach to the Meaning of Database Updates and Active Rules 21 Iakovos Motak..