4,495 research outputs found
Southern Annular Mode-like changes in southwestern Patagonia at centennial timescales over the last three millennia
Late twentieth-century instrumental records reveal a persistent southward shift of the Southern Westerly Winds during austral summer and autumn associated with a positive trend of the Southern Annular Mode (SAM) and contemporaneous with glacial recession, steady increases in atmospheric temperatures and CO2 concentrations at a global scale. However, despite the clear importance of the SAM in the modern/future climate, very little is known regarding its behaviour during pre-Industrial times. Here we present a stratigraphic record from Lago Cipreses (51S), southwestern Patagonia, that reveals recurrent B200-year long dry/warm phases over the last three millennia, which we interpret as positive SAM-like states. These correspond in timing with the Industrial revolution, the Mediaeval Climate Anomaly, the Roman and Late Bronze Age Warm Periods and alternate with cold/wet multicentennial phases in European palaeoclimate records. We conclude that SAM-like changes at centennial timescales in southwestern Patagonia represent in-phase interhemispheric coupling of palaeoclimate over the last 3,000 years through atmospheric teleconnections.Fil: Moreno, Patricio. Universidad de Chile; ChileFil: Vilanova, Isabel. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; ArgentinaFil: Villa Martinez, R.. Universidad de Chile; ChileFil: Garreaud, R. D.. Universidad de Chile; ChileFil: Rojas, M.. Universidad de Chile; ChileFil: De Pol Holz, R.. Universidad de Chile; Chil
Planck pre-launch status: Low Frequency Instrument calibration and expected scientific performance
We give the calibration and scientific performance parameters of the Planck
Low Frequency Instrument (LFI) measured during the ground cryogenic test
campaign. These parameters characterise the instrument response and constitute
our best pre-launch knowledge of the LFI scientific performance. The LFI shows
excellent stability and rejection of instrumental systematic effects;
measured noise performance shows that LFI is the most sensitive instrument of
its kind. The set of measured calibration parameters will be updated during
flight operations through the end of the mission.Comment: Accepted for publications in Astronomy and Astrophysics. Astronomy &
Astrophysics, 2010 (acceptance date: 12 Jan 2010
Clonal human fetal ventral mesencephalic dopaminergic neuron precursors for cell therapy research
A major challenge for further development of drug screening procedures, cell replacement therapies and developmental studies is the identification of expandable human stem cells able to generate the cell types needed. We have previously reported the generation of an immortalized polyclonal neural stem cell (NSC) line derived from the human fetal ventral mesencephalon (hVM1). This line has been biochemically, genetically, immunocytochemically and electrophysiologically characterized to document its usefulness as a model system for the generation of A9 dopaminergic neurons (DAn). Long-term in vivo transplantation studies in parkinsonian rats showed that the grafts do not mature evenly. We reasoned that diverse clones in the hVM1 line might have different abilities to differentiate. In the present study, we have analyzed 9 hVM1 clones selected on the basis of their TH generation potential and, based on the number of v-myc copies, v-myc down-regulation after in vitro differentiation, in vivo cell cycle exit, TH+ neuron generation and expression of a neuronal mature marker (hNSE), we selected two clones for further in vivo PD cell replacement studies. The conclusion is that homogeneity and clonality of characterized NSCs allow transplantation of cells with controlled properties, which should help in the design of long-term in vivo experimentsThis work was supported by grants from the Spanish Ministry of Economy and Competitiveness (formerly Science and Innovation; PLE2009-0101,
SAF2010-17167), Comunidad AutĂłnoma Madrid (S2011-BMD-2336), Instituto Salud Carlos III (RETICS TerCel, RD06/0010/0009) and European Union (Excell, NMP4-SL-2008-214706). This work was also supported by an institutional grant from Foundation RamĂłn Areces to the Center of Molecular Biology Severo Ocho
Boxy/peanut/X bulges, barlenses and the thick part of galactic bars: What are they and how did they form?
Bars have a complex three-dimensional shape. In particular their inner part
is vertically much thicker than the parts further out. Viewed edge-on, the
thick part of the bar is what is commonly known as a boxy-, peanut- or X- bulge
and viewed face-on it is referred to as a barlens. These components are due to
disc and bar instabilities and are composed of disc material. I review here
their formation, evolution and dynamics, using simulations, orbital structure
theory and comparisons to observations.Comment: 21 pages, 7 figures, invited review to appear in "Galactic Bulges",
E. Laurikainen, R. Peletier, D. Gadotti, (eds.), Springe
Overview of Plasma Lens Experiments and Recent Results at SPARC_LAB
Beam injection and extraction from a plasma module is still one of the
crucial aspects to solve in order to produce high quality electron beams with a
plasma accelerator. Proper matching conditions require to focus the incoming
high brightness beam down to few microns size and to capture a high divergent
beam at the exit without loss of beam quality. Plasma-based lenses have proven
to provide focusing gradients of the order of kT/m with radially symmetric
focusing thus promising compact and affordable alternative to permanent magnets
in the design of transport lines. In this paper an overview of recent
experiments and future perspectives of plasma lenses is reported
Rings and bars: unmasking secular evolution of galaxies
Secular evolution gradually shapes galaxies by internal processes, in
contrast to early cosmological evolution which is more rapid. An important
driver of secular evolution is the flow of gas from the disk into the central
regions, often under the influence of a bar. In this paper, we review several
new observational results on bars and nuclear rings in galaxies. They show that
these components are intimately linked to each other, and to the properties of
their host galaxy. We briefly discuss how upcoming observations, e.g., imaging
from the Spitzer Survey of Stellar Structure in Galaxies (S4G), will lead to
significant further advances in this area of research.Comment: Invited review at "Galaxies and their Masks", celebrating Ken
Freeman's 70-th birthday, Sossusvlei, Namibia, April 2010. To be published by
Springer, New York, editors D.L. Block, K.C. Freeman, & I. Puerari; minor
change
Stellar populations of bulges at low redshift
This chapter summarizes our current understanding of the stellar population
properties of bulges and outlines important future research directions.Comment: Review article to appear in "Galactic Bulges", Editors: Laurikainen
E., Peletier R., Gadotti D., Springer Publishing. 34 pages, 12 figure
The Quijote CMB Experiment
We present the current status of the QUIJOTE (Q-U-I JOint TEnerife) CMB
Experiment, a new instrument which will start operations early 2009 at Teide
Observatory, with the aim of characterizing the polarization of the CMB and
other processes of galactic and extragalactic emission in the frequency range
10-30 GHz and at large angular scales. QUIJOTE will be a valuable complement at
low frequencies for the PLANCK mission, and will have the required sensitivity
to detect a primordial gravitational-wave component if the tensor-to-scalar
ratio is larger than r=0.05.Comment: 9 pages, 5 figures. To appear in "Highlights of Spanish Astrophysics
V", Proceedings of the VIII Scientific Meeting of the Spanish Astronomical
Society (SEA) held in Santander, 7-11 July, 2008. Edited by J. Gorgas, L. J.
Goicoechea, J. I. Gonzalez-Serrano, J. M. Dieg
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