45 research outputs found
Next-to-Minimal Supersymmetric Model Higgs Scenarios for Partially Universal GUT Scale Boundary Conditions
We examine the extent to which it is possible to realize the NMSSM "ideal
Higgs" models espoused in several papers by Gunion et al in the context of
partially universal GUT scale boundary conditions. To this end we use the
powerful methodology of nested sampling. We pay particular attention to whether
ideal-Higgs-like points not only pass LEP constraints but are also acceptable
in terms of the numerous constraints now available, including those from the
Tevatron and -factory data, and the relic density .
In general for this particular methodology and range of parameters chosen, very
few points corresponding to said previous studies were found, and those that
were found were at best away from the preferred relic density value.
Instead, there exist a class of points, which combine a mostly singlet-like
Higgs with a mostly singlino-like neutralino coannihilating with the lightest
stau, that are able to effectively pass all implemented constraints in the
region . It seems that the spin-independent direct detection cross
section acts as a key discriminator between ideal Higgs points and the hard to
detect singlino-like points.Comment: 22 pages, 15 figure
Global fits of the Non-Universal Higgs Model
We carry out global fits to the Non-Universal Higgs Model (NUHM), applying
all relevant present-day constraints. We present global probability maps for
the NUHM parameters and observables (including collider signatures, direct and
indirect detection quantities), both in terms of posterior probabilities and in
terms of profile likelihood maps. We identify regions of the parameter space
where the neutralino dark matter in the model is either bino-like, or else
higgsino-like with mass close to 1 TeV and spin-independent scattering cross
section ~ 10^{-9}-10^{-8} pb. We trace the occurrence of the higgsino-like
region to be a consequence of a mild focusing effect in the running of one of
the Higgs masses, the existence of which in the NUHM we identify in our
analysis. Although the usual bino-like neutralino is more prominent,
higgsino-like dark matter cannot be excluded, however its significance strongly
depends on the prior and statistics used to assess it. We note that, despite
experimental constraints often favoring different regions of parameter space to
the Constrained MSSM, most observational consequences appear fairly similar,
which will make it challenging to distinguish the two models experimentallyComment: Major revision following referee comments. Now includes profile
likelihood results. Matches PRD accepted versio
ModernizaciĂłn del intercambio de datos para el monitoreo y la predicciĂłn del sistema Tierra
FlyMine: an integrated database for Drosophila and Anopheles genomics.
FlyMine is a data warehouse that addresses one of the important challenges of modern biology: how to integrate and make use of the diversity and volume of current biological data. Its main focus is genomic and proteomics data for Drosophila and other insects. It provides web access to integrated data at a number of different levels, from simple browsing to construction of complex queries, which can be executed on either single items or lists
From Vampire to Apollo: William Blake's Ghosts of the Flea (c. 1819-20)
Varleyâs Zodiacal Physiognomy and Blakeâs Visionary Heads are the two mainstays of a project which involved sĂ©ance-like meetings at Varleyâs house. While the lights were still on, Varleyâs guests would have listened to the stories about the flea. With The Ghost of a Flea in front of them, the recitals of the fleaâs pompous speeches, combined with the fact that it was just a ghost who leered after human blood, Varleyâs guests may have laughed very heartily, if not in front of him then behind his back. Each evening followed the same protocol. When the lights were off, Varley would call out a name and Blake would look around, suddenly exclaiming âThere he is!â and start drawing. The flea is the most striking of the Visionary Heads, though it is not the only head which exists in different versions. If appearance is elemental to any kind of judgement of one human being of another, then Blake deliberately confused Varley. By working up the sketch, he played on Varleyâs expectations; he presented him with an extraordinary and very puzzling painting, The Ghost of a Flea. But why, if Blake could have chosen any monster, did he settle on the ghost of a flea
A chemical survey of exoplanets with ARIEL
Thousands of exoplanets have now been discovered with a huge range of masses, sizes and orbits: from rocky Earth-like planets to large gas giants grazing the surface of their host star. However, the essential nature of these exoplanets remains largely mysterious: there is no known, discernible pattern linking the presence, size, or orbital parameters of a planet to the nature of its parent star. We have little idea whether the chemistry of a planet is linked to its formation environment, or whether the type of host star drives the physics and chemistry of the planetâs birth, and evolution. ARIEL was conceived to observe a large number (~1000) of transiting planets for statistical understanding, including gas giants, Neptunes, super-Earths and Earth-size planets around a range of host star types using transit spectroscopy in the 1.25â7.8 ÎŒm spectral range and multiple narrow-band photometry in the optical. ARIEL will focus on warm and hot planets to take advantage of their well-mixed atmospheres which should show minimal condensation and sequestration of high-Z materials compared to their colder Solar System siblings. Said warm and hot atmospheres are expected to be more representative of the planetary bulk composition. Observations of these warm/hot exoplanets, and in particular of their elemental composition (especially C, O, N, S, Si), will allow the understanding of the early stages of planetary and atmospheric formation during the nebular phase and the following few million years. ARIEL will thus provide a representative picture of the chemical nature of the exoplanets and relate this directly to the type and chemical environment of the host star. ARIEL is designed as a dedicated survey mission for combined-light spectroscopy, capable of observing a large and well-defined planet sample within its 4-year mission lifetime. Transit, eclipse and phase-curve spectroscopy methods, whereby the signal from the star and planet are differentiated using knowledge of the planetary ephemerides, allow us to measure atmospheric signals from the planet at levels of 10â100 part per million (ppm) relative to the star and, given the bright nature of targets, also allows more sophisticated techniques, such as eclipse mapping, to give a deeper insight into the nature of the atmosphere. These types of observations require a stable payload and satellite platform with broad, instantaneous wavelength coverage to detect many molecular species, probe the thermal structure, identify clouds and monitor the stellar activity. The wavelength range proposed covers all the expected major atmospheric gases from e.g. H2O, CO2, CH4 NH3, HCN, H2S through to the more exotic metallic compounds, such as TiO, VO, and condensed species. Simulations of ARIEL performance in conducting exoplanet surveys have been performed â using conservative estimates of mission performance and a full model of all significant noise sources in the measurement â using a list of potential ARIEL targets that incorporates the latest available exoplanet statistics. The conclusion at the end of the Phase A study, is that ARIEL â in line with the stated mission objectives â will be able to observe about 1000 exoplanets depending on the details of the adopted survey strategy, thus confirming the feasibility of the main science objectives.Peer reviewedFinal Published versio
AVONET: Morphological, ecological and geographical data for all birds
Functional traits offer a rich quantitative framework for developing and testing theories in evolutionary biology, ecology and ecosystem science. However, the potential of functional traits to drive theoretical advances and refine models of global change can only be fully realised when species-level information is complete. Here we present the AVONET dataset containing comprehensive functional trait data for all birds, including six ecological variables, 11 continuous morphological traits, and information on range size and location. Raw morphological measurements are presented from 90,020 individuals of 11,009 extant bird species sampled from 181 countries. These data are also summarised as species averages in three taxonomic formats, allowing integration with a global phylogeny, geographical range maps, IUCN Red List data and the eBird citizen science database. The AVONET dataset provides the most detailed picture of continuous trait variation for any major radiation of organisms, offering a global template for testing hypotheses and exploring the evolutionary origins, structure and functioning of biodiversity.Fil: Tobias, Joseph A.. Imperial College London; Reino Unido. University of Oxford; Reino UnidoFil: Sheard, Catherine. University of Oxford; Reino Unido. University of Bristol; Reino UnidoFil: Pigot, Alex L.. University of Oxford; Reino Unido. University College London; Estados UnidosFil: Devenish, Adam J. M.. Imperial College London; Reino UnidoFil: Yang, Jingyi. Imperial College London; Reino UnidoFil: Sayol, Ferran. University College London; Estados UnidosFil: Neate Clegg, Montague H. C.. University of Oxford; Reino Unido. University of Utah; Estados UnidosFil: Alioravainen, Nico. University of Oxford; Reino Unido. Natural Resources Institute Finland; FinlandiaFil: Weeks, Thomas L.. Imperial College London; Reino Unido. Natural History Museum; Reino UnidoFil: Barber, Robert A.. Imperial College London; Reino UnidoFil: Walkden, Patrick A.. Imperial College London; Reino Unido. Natural History Museum; Reino UnidoFil: MacGregor, Hannah E. A.. University of Oxford; Reino Unido. University of Bristol; Reino UnidoFil: Jones, Samuel E. I.. University of Oxford; Reino Unido. University of London; Reino UnidoFil: Vincent, Claire. OrganizaciĂłn de Las Naciones Unidas; ArgentinaFil: Phillips, Anna G.. Senckenberg Biodiversity And Climate Research Centre; AlemaniaFil: Marples, Nicola M.. Trinity College; Estados UnidosFil: Montaño Centellas, Flavia A.. Universidad Mayor de San AndrĂ©s; Bolivia. University of Florida; Estados UnidosFil: Leandro Silva, Victor. Universidade Federal de Pernambuco; BrasilFil: Claramunt, Santiago. University of Toronto; CanadĂĄ. Royal Ontario Museum; CanadĂĄFil: Darski, Bianca. Universidade Federal do Rio Grande do Sul; BrasilFil: Freeman, Benjamin G.. University of British Columbia; CanadĂĄFil: Bregman, Tom P.. University of Oxford; Reino Unido. Future-Fit Foundation; Reino UnidoFil: Cooney, Christopher R.. University Of Sheffield; Reino UnidoFil: Hughes, Emma C.. University Of Sheffield; Reino UnidoFil: Capp, Elliot J. R.. University Of Sheffield; Reino UnidoFil: Varley, ZoĂ« K.. University Of Sheffield; Reino Unido. Natural History Museum; Reino UnidoFil: Friedman, Nicholas R.. Okinawa Institute of Science and Technology Graduate University; JapĂłnFil: Korntheuer, Heiko. Johannes Gutenberg Universitat Mainz; AlemaniaFil: Corrales Vargas, Andrea. Universidad Nacional de Costa Rica; Costa RicaFil: GarcĂa, Natalia Cristina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentin
A comprehensive candidate gene approach identifies genetic variation associated with osteosarcoma
<p>Abstract</p> <p>Background</p> <p>Osteosarcoma (OS) is a bone malignancy which occurs primarily in adolescents. Since it occurs during a period of rapid growth, genes important in bone formation and growth are plausible modifiers of risk. Genes involved in DNA repair and ribosomal function may contribute to OS pathogenesis, because they maintain the integrity of critical cellular processes. We evaluated these hypotheses in an OS association study of genes from growth/hormone, bone formation, DNA repair, and ribosomal pathways.</p> <p>Methods</p> <p>We evaluated 4836 tag-SNPs across 255 candidate genes in 96 OS cases and 1426 controls. Logistic regression models were used to estimate the odds ratios (OR) and 95% confidence intervals (CI).</p> <p>Results</p> <p>Twelve SNPs in growth or DNA repair genes were significantly associated with OS after Bonferroni correction. Four SNPs in the DNA repair gene <it>FANCM </it>(ORs 1.9-2.0, <it>P </it>= 0.003-0.004) and 2 SNPs downstream of the growth hormone gene <it>GH1 </it>(OR 1.6, <it>P </it>= 0.002; OR 0.5, <it>P </it>= 0.0009) were significantly associated with OS. One SNP in the region of each of the following genes was significant: <it>MDM2</it>, <it>MPG</it>, <it>FGF2</it>, <it>FGFR3</it>, <it>GNRH2</it>, and <it>IGF1</it>.</p> <p>Conclusions</p> <p>Our results suggest that several SNPs in biologically plausible pathways are associated with OS. Larger studies are required to confirm our findings.</p
The Paris Commune in the British socialist imagination, 1871â1914
This article is concerned with manifestations of the memory of the Paris Commune in Britain in the decades after 1871. It is about how the Commune was incorporated into the mythology, the canon, of British socialism, and how the memory of the Commune furnished British socialism with powerful and useful symbols. In highlighting the ways in which the events of 1871 captured the British socialist imagination, what follows shows how, despite its oft-emphasised insularity, British socialism was made through the incorporation and appropriation of both native and foreign ideas, symbols, and traditions. The powerful mythologies and symbolism associated with the Commune were taken up by socialists in Britain, and highlight an important intersection between British and French political cultures in the late nineteenth and early twentieth centuries
Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
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