2,192 research outputs found
Papel del logopeda en un centro gerontológico de estancias diurnas
[Resumen] El aumento de población anciana en nuestra sociedad es un hecho que ha provocado la aparición de nuevos recursos socio-sanitarios que cubran sus necesidades. El Centro Gerontológico de Estancias Diurnas es un servicio multidisciplinar diurno que se ocupa de la atención social y sanitaria, con actuación terapéutica y preventiva, de los mayores facilitando la vida laboral de las personas que se ocupan ordinariamente de su cuidado. Los centros de día deben proporcionar una atención integral debiendo, por tanto, estar constituidos por un equipo profesional multidisciplinar en el que la figura del logopeda esté presente desarrollando una labor específica. Parece, por tanto, interesante delimitar las funciones básicas a desempeñar, los trastornos más comunes susceptibles de intervención, así como, algunas directrices a tener en cuenta.[Abstract] The increase of the senior population in our society is an event that has provoked the appeareance of a new sort of social and sanitary recource, a structure that has to be concerned with the needs of this population. The gerontologic day-center is in brief a multidisciplinar service, that works during day time, treating the social and sanitary occupation of our elder with both therapeutic and preventive acts. This to provide a normal working life for the people who are usually taking care of these people. Day-centers have to answer these needs with a complete service, and for that reason they have to apile to a multidisciplinar staff in wich the speech-therapist develops a specific role. It seems though interesting to define the basic functions that a professional speech-therapist has to perform, such as the most common disorders capable of treatment and general intervention, as well derectives to bear in mind
Ionic liquid/metal salt mixtures at the graphene interface: A density functional theory approach
[Abstract] The interaction of graphene sheets with metal cations is very relevant because of the modifications that are
induced in the electrochemical properties of the 2D material. Ionic liquids are a promising kind of materials with
several applications in electrochemical devices, so understanding how they affect the graphene-metal interaction
is key for their practical implementation. Therefore, we have studied the adsorption of a mixture of an ionic liquid
and a metal salt on a graphene surface by means of first-principles calculations. Several metals were chosen to
analyze the effect they have on the optoelectronic properties of the graphene monolayer and to understand the
trends in their adsorption behavior. We have characterized the ground state configurations in terms of their
binding energies and the distance between the metal atom and the graphene layer. From the analysis of the
charge transfer behavior, calcium and magnesium have been identified as the species that transfer the highest and
the lowest amount of charge, respectively, which is related to their ionization energies. Band structure diagrams
and projected density of states calculations also show that the energy shift of the Dirac cone increases with
the degree of charge transfer. In addition, a stronger interaction of magnesium with the ionic liquid compared
to that of other metal atoms was observed. The analysis of several electromagnetic parameters indicated an
anisotropic behavior for electric fields polarized both perpendicular and parallel to the graphene layer. Our
density functional theory study offers fundamental insights into the adsorption behavior of ionic liquids mixed
with metal ions on monolayer graphene.The financial support of the Spanish Ministry of Science and Innovation (PID2021-126148NA-I00 funded by MCIN/AEI/10.13039/ 501100011033/FEDER, UE) is gratefully acknowledged. Moreover, this work was funded by the Xunta de Galicia (GRC ED431C 2020/10). A. R.-P. and J.M.O.-M. thank the Spanish Ministry of Education for their FPU grants (FPU16/01500 and FPU18/01597). C. D. R. F. thanks the support of Xunta de Galicia through the grant ED481A-2018/032. T. M. M. acknowledges her contract funded by the pilot program of the USC for the recruitment of distinguished research personnel—call 2021 under the agreement between the USC and the Santander Bank for 2021–2024. H.M.C. thanks the USC for his “Convocatoria de Recualificación do Sistema Universitario Español-Margarita Salas” postdoctoral grant under the “Plan de Recuperación Transformación” program funded by the Spanish Ministry of Universities with European Union's NextGenerationEU funds. This work was supported by the Fundação para a Ciência e a Tecnologia (FCT) (funded by national funds through the FCT/MCTES (PIDDAC)) to CIQUP, Faculty of Science, University of Porto (Project UIDB/00081/2020), IMS-Institute of Molecular Sciences (LA/P/0056/2020). Facilities provided by the Galician Supercomputing Centre (CESGA) are also acknowledged.Xunta de Galicia ; ED431C 2020/10Xunta de Galicia ; ED481A-2018/03
Characterizing zebra crossing zones using LiDAR data
Light detection and ranging (LiDAR) scanning in urban environments leads to accurate and dense three-dimensional point clouds where the different elements in the scene can be precisely characterized. In this paper, two LiDAR-based algorithms that complement each other are proposed. The first one is a novel profiling method robust to noise and obstacles. It accurately characterizes the curvature, the slope, the height of the sidewalks, obstacles, and defects such as potholes. It was effective for 48 of 49 detected zebra crossings, even in the presence of pedestrians or vehicles in the crossing zone. The second one is a detailed quantitative summary of the state of the zebra crossing. It contains information about the location, the geometry, and the road marking. Coarse grain statistics are more prone to obstacle-related errors and are only fully reliable for 18 zebra crossings free from significant obstacles. However, all the anomalous statistics can be analyzed by looking at the associated profiles. The results can help in the maintenance of urban roads. More specifically, they can be used to improve the quality and safety of pedestrian routesConsellería de Cultura, Educación e Ordenación Universitaria, Grant/Award Numbers: accreditation 2019-2022 ED431G-2019/04, 2022-2024, ED431C2022/16, ED481A-2020/231; European Regional Development Fund (ERDF); CiTIUS-Research Center in Intelligent Technologies of the University of Santiago de Compostela as a Research Center of the Galician University System; Ministry of Economy and Competitiveness, Government of Spain, Grant/Award Number: PID2019-104834GB-I00; National Department of Traffic (DGT) through the project Analysis of Indicators Big-Geodata on Urban Roads for the Dynamic Design of Safe School Roads, Grant/Award Number: SPIP2017-02340S
A Low-Cost Visible Light Positioning System for Indoor Positioning
Currently, a high percentage of the world’s population lives in urban areas, and this proportion will increase in the coming decades. In this context, indoor positioning systems (IPSs) have been a topic of great interest for researchers. On the other hand, Visible Light Communication (VLC) systems have advantages over RF technologies; for instance, they do not need satellite signals or the absence of electromagnetic interference to achieve positioning. Nowadays, in the context of Indoor Positioning (IPS), Visible Light Positioning (VLP) systems have become a strong alternative to RF-based systems, allowing the reduction in costs and time to market. This paper shows a low cost VLP solution for indoor systems. This includes multiple programmable beacons and a receiver which can be plugged to a smartphone running a specific app. The position information will be quickly and securely available through the interchange between the receiver and any configurable LED-beacon which is strategically disposed in an area. The implementation is simple, inexpensive, and no direct communication with any data server is required.This research was funded by INDRA-Adecco Foundation Chair on Accessible Technology, Comunidad de Madrid and the FSE/FEDER Program under grant SINFOTON2-CM (S2018/NMT-4326) and the UNIVERSIDAD CARLOS III DE MADRID under grant 2020/00038/001
Encapsulation of Cynara Cardunculus Guaiane-type Lactones in Fully Organic Nanotubes Enhances Their Phytotoxic Properties
The encapsulation of bioactive natural products has emerged as a relevant tool for modifying the poor physicochemical properties often exhibited by agrochemicals. In this regard, natural guaiane-type sesquiterpene lactones isolated from Cynara cardunculus L. have been encapsulated in a core/shell nanotube(c)agrochemical system. Monitoring of the F and O signals in marked sesquiterpenes confirmed that the compound is present in the nanotube cavity. These structures were characterized using scanning transmission electron microscopy-X-ray energy-dispersive spectrometry techniques, which revealed the spatial layout relationship and confirmed encapsulation of the sesquiterpene lactone derivative. In addition, biological studies were performed with aguerin B (1), cynaropicrin (2), and grosheimin (3) on the inhibition of germination, roots, and shoots in weeds (Phalaris arundinacea L., Lolium perenne L., and Portulaca oleracea L.). Encapsulation of lactones in nanotubes gives better results than those for the nonencapsulated compounds, thereby reinforcing the application of fully organic nanotubes for the sustainable use of agrochemicals in the future.This research was funded by the Agencia Estatal de Investigacion, Ministerio de Ciencia e Innovacion, grant number PID2020-115747RB-I00/AEI/10.13039/501100011033, Spain. F. J.R.M thanks the University of Cadiz for postdoctoral support under grant 2018-009/PU/EPIF-FPI-CT/CP. Furthermore, this work has received financial support from the Junta de Andalucia (FQM334), MINECO/FEDER (projects MAT2017-87579-R). This project has received funding from the European Union's Horizon 2020 research and innovation program under grant 823717-ESTEEM3. STEM studies were performed at the DME Facilities of SCCYT at the University of Cadiz. We also thank Semillas Fito (Barcelona, Spain) for kindly supplying us with wheat seeds
Senolytic Activity of Small Molecular Polyphenols from Olive Restores Chondrocyte Redifferentiation and Promotes a Pro-Regenerative Environment in Osteoarthritis
[Abstract]
Articular cartilage and synovial tissue from patients with osteoarthritis (OA) show an overactivity of connexin43 (Cx43) and accumulation of senescent cells associated with disrupted tissue regeneration and disease progression. The aim of this study was to determine the effect of oleuropein on Cx43 and cellular senescence for tissue engineering and regenerative medicine strategies for OA treatment. Oleuropein regulates Cx43 promoter activity and enhances the propensity of hMSCs to differentiate into chondrocytes and bone cells, reducing adipogenesis. This small molecule reduce Cx43 levels and decrease Twist-1 activity in osteoarthritic chondrocytes (OACs), leading to redifferentiation, restoring the synthesis of cartilage ECM components (Col2A1 and proteoglycans), and reducing the inflammatory and catabolic factors mediated by NF-kB (IL-1ß, IL-6, COX-2 and MMP-3), in addition to lowering cellular senescence in OACs, synovial and bone cells. Our in vitro results demonstrate the use of olive-derived polyphenols, such as oleuropein, as potentially effective therapeutic agents to improve chondrogenesis of hMSCs, to induce chondrocyte re-differentiation in OACs and clearing out senescent cells in joint tissues in order to prevent or stop the progression of the disease.Xunta de Galicia; IN607B 2017/21Xunta de Galicia; ED481A-2015/188Xunta de Galicia; IN606B-2019/004Xunta de Galicia; IN606B-2017/014This work was supported in part through funding from the Spanish Foundation for Research on Bone and Mineral Metabolism (FEIOMM), grant PRECIPITA-2015-000139 from the FECYT-Ministry of Economy and Competitiveness (to M.D.M.), grant PI16/00035 and PI19/00145 from the Health Institute ‘Carlos III’ (ISCIII, Spain), the European Regional Development Fund, ‘A way of making Europe’ from the European Union (to M.D.M.) and a grant from Xunta de Galicia IN607B 2017/21 (to M.D.M.). M.V.-E. was funded with a predoctoral (ED481A-2015/188) and a postdoctoral fellowship (IN606B-2019/004) from Xunta de Galicia. P.C.-F. was funded with a postdoctoral fellowship (IN606B-2017/014) from Xunta de Galicia
Survival analysis of time to SARS-CoV-2 PCR negativisation to optimise PCR prescription in health workers: the Henares COVID-19 healthcare workers cohort study.
Objectives Reverse transcriptase PCR (RT-PCR) is considered the gold standard in diagnosing COVID-19. Infected healthcare workers do not go back to work until RT-PCR has demonstrated that the virus is no longer present in the upper respiratory tract. The aim of this study is to determine the most efficient time to perform RT-PCR prior to healthcare workers’ reincorporation.
Materials and methods This is a cohort study of healthcare workers with RT-PCR-confirmed COVID-19. Data were collected using the medical charts of healthcare workers and completed with a telephone interview. Kaplan-Meier curves were used to determine the influence of several variables on the time to RT-PCR negativisation. The impact of the variables on survival was assessed using the Breslow test. A Cox regression model was developed including the associated variables.
Results 159 subjects with a positive RT-PCR out of 374 workers with suspected COVID-19 were included. The median time to negativisation was 25 days from symptom onset (IQR 20–35 days). Presence of IgG, dyspnoea, cough and throat pain were associated with significant longer time to negativisation. Cox logistic regression was used to adjust for confounding variables. Only dyspnoea and cough remained in the model as significant determinants of prolonged negativisation time. Adjusted HRs were 0.68 (0.48–096) for dyspnoea and 0.61 (0.42–0.88) for dry cough.
Conclusions RT-PCR during the first 3 weeks leads to a high percentage of positive results. In the presence of respiratory symptoms, negativisation took nearly 1 week more. Those who developed antibodies needed longer time to negativisate.pre-print396 K
Menstrual problems and lifestyle among Spanish university women
ABSTRACT: Menstrual problems affect many young women worldwide, conditioning both their academic performance and quality of life. This study sought to analyse the prevalence of menstrual problems and their possible relationship with lifestyle among Spanish university women, as part of a research project (UniHcos Project) involving a cohort of 11 Spanish universities with 7208 university students. A descriptive analysis was performed using the bivariate chi-square test and the Student’s t-test together with a binary logistic regression, in which the dependent variable was ‘suffering from menstrual problems’. Menstrual problems were identified in 23.8% of the students, representing women who paid more visits to the doctor and to emergency rooms, and who consumed more painkillers and contraceptives. In relation to dietary preferences, menstrual problems were 1.39 (CI 95% 1.22–1.61; p = 0.000) times more likely among women classified as high-risk alcohol users according to the AUDIT questionnaire, and 1.187 (CI 95% 1.029–1.370; p = 0.019) times greater among those who consumed sweets daily, 1.592 (CI 95% 1.113–2.276; p = 0.011) times more frequent among those who eat fish daily, and 1.199 (CI 95% 1.004–1.432; p = 0.045) times greater among those who were dieting. Menstrual problems affect many college students and potentially modifiable lifestyle variables exist which may influence their prevalence. It would be interesting to develop programmes to promote women’s health in the university context.This research was funded by the National Drug Plan, Ministry of Health, Social Services and Equality of Spain (Grant numbers: 2010|145 and 2013|034) and Instituto de Salud Carlos III (Grant number: PI16/01947)
Transferencia y colaboración entre el estudiantado de la Escuela de Enfermería y la Politécnica en el Campus Viriato de Zamora (Transcol Campus Viriato)
Memoria ID2022-181 Ayudas de la Universidad de Salamanca para la innovación docente, curso 2022-2023
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