Electronic structure and dynamics of optically excited single-wall carbon nanotubes

We have studied the electronic structure and charge-carrier dynamics of individual single-wall carbon nanotubes (SWNTs) and nanotube ropes using optical and electron-spectroscopic techniques. The electronic structure of semiconducting SWNTs in the band-gap region is analyzed using near-infrared absorption spectroscopy. A semi-empirical expression for $E_{11}^{\rm S}$ transition energies, based on tight-binding calculations is found to give striking agreement with experimental data. Time-resolved PL from dispersed SWNT-micelles shows a decay with a time constant of about 15 ps. Using time-resolved photoemission we also find that the electron-phonon ({\it e-ph}) coupling in metallic tubes is characterized by a very small {\it e-ph} mass-enhancement of 0.0004. Ultrafast electron-electron scattering of photo-excited carriers in nanotube ropes is finally found to lead to internal thermalization of the electronic system within about 200 fs.Comment: 10 pages, 10 figures, submitted to Applied Physics

JS-K, a Nitric Oxide Prodrug, Has Enhanced Cytotoxicity in Colon Cancer Cells with Knockdown of Thioredoxin Reductase 1

The selenoenzyme thioredoxin reductase 1 has a complex role relating to cell growth. It is induced as a component of the cellular response to potentially mutagenic oxidants, but also appears to provide growth advantages to transformed cells by inhibiting apoptosis. In addition, selenocysteine-deficient or alkylated forms of thioredoxin reductase 1 have also demonstrated oxidative, pro-apoptotic activity. Therefore, a greater understanding of the role of thioredoxin reductase in redox initiated apoptotic processes is warranted.The role of thioredoxin reductase 1 in RKO cells was evaluated by attenuating endogenous thioredoxin reductase 1 expression with siRNA and then either inducing a selenium-deficient thioredoxin reductase or treatment with distinct redox challenges including, hydrogen peroxide, an oxidized lipid, 4-hydroxy-2-nonenol, and a nitric oxide donating prodrug. Thioredoxin redox status, cellular viability, and effector caspase activity were measured.In cells with attenuated endogenous thioredoxin reductase 1, a stably integrated selenocysteine-deficient form of the enzyme was induced but did not alter either the thioredoxin redox status or the cellular growth kinetics. The oxidized lipid and the nitric oxide donor demonstrated enhanced cytotoxicity when thioredoxin reductase 1 was knocked-down; however, the effect was more pronounced with the nitric oxide prodrug. These results are consistent with the hypothesis that attenuation of the thioredoxin-system can promote apoptosis in a nitric oxide-dependent manner

HUT observations of carbon monoxide in the coma of Comet Levy (1990c)

Observations of comet Levy (1990c) were made with the Hopkins Ultraviolet Telescope during the Astro-1 Space Shuttle mission on 10 Dec. 1990. The spectrum, covering the wavelength range 415 to 1850 A at a spectral emission of 3 A (in first order), shows the presence of carbon monoxide and atomic hydrogen, carbon, and sulfur in the coma. Aside from H I Lyman-beta, no cometary features are detected below 1200 A, although cometary O I and O II would be masked by the same emissions present in the day airglow spectrum. The 9.4 x 116 arcsec aperture corresponds to 12,000 x 148,000 km at the comet. The derived production rate of CO relative to water, 0.13 + or - 0.02, compared with the same ratio derived from IUE observations (made in Sep. 1990) which sample a much smaller region of the coma, 0.04 + or - 0.01, suggests the presence of an extended source of CO, as was found in comet Halley. Upper limits on Ne and Ar abundance are within an order of magnitude or solar abundances

A Study of the Reionization History of Intergalactic Helium with FUSE and VLT

We obtained high-resolution VLT and FUSE spectra of the quasar HE2347-4342 to study the properties of the intergalactic medium between redshifts z=2.0-2.9. The high-quality optical spectrum allows us to identify approximately 850 HeII absorption components with column densities between N~5X10^11 and $ 10^18 cm^-2. The reprocessed FUSE spectrum extends the wavelength coverage of the HeII absorption down to an observed wavelength of 920 A. Approximately 1400 HeII absorption components are identified, including 917 HeII Ly-alpha systems and some of their HeII Ly-beta, Ly-gamma, and Ly-delta counterparts. The ionization structure of HeII is complex, with approximately 90 components that are not detected in the hydrogen spectrum. These components may represent the effect of soft ionizing sources. The ratio Eta=N(HeII)/N(HI) varies approximately from unity to more than a thousand, with a median value of 62 and a distribution consistent with the intrinsic spectral indices of quasars. This suggests that the dominant ionizing field is from the accumulated quasar radiation, with contributions from other soft sources such as star-forming regions and obscured AGN, which do not ionize helium. We find an evolution in Eta toward smaller values at lower redshift, with the gradual disappearance of soft components. At redshifts z>2.7, the large but finite increase in the HeII opacity, Tau=5+/-1, suggests that we are viewing the end stages of a reionization process that began at an earlier epoch. Fits of the absorption profiles of unblended lines indicate comparable velocities between hydrogen and He^+ ions. At hydrogen column densities N<3X10^12 cm^-2 the number of forest lines shows a significant deficit relative to a power law, and becomes negligible below N=10^11 cm^-2.Comment: 40 pages, 10 Postscript figures, uses Aastex.sty The Astrophysical Journal, in pres

Reducing Cold-Start Emissions by Microwave-Based Catalyst Heating: Simulation Studies

During cold start of vehicles with gasoline combustion engines, conversion of pollutants in the exhaust gas to inert products is very low due to low catalyst temperature. Only above the light-off temperature, significant conversion can be achieved. Previous strategies to reduce cold-start emissions have been focused on developing catalysts with a low light-off temperature. Electric catalyst heating systems have also been discussed repeatedly. A disadvantage of such systems is the required volume flow through the catalyst, which is necessary for heat transfer to the catalyst. In contrast, microwave-assisted heating allows direct introduction of thermal power into the catalyst due to dielectric losses of the catalyst materials. This work analyses simulation-based the influence of the material on the heatability by microwaves. The focus is on the substrate materials rather than the catalytically active coatings, since the substrate represents the part in the TWC where most of the dielectric losses occur. For this purpose, the temperature-dependent dielectric material properties of cordierite and silicon carbide (SiC) are investigated. The determined material properties are then transferred to a simulation model that calculates heat distribution and heat insertion based on the electromagnetic field distribution. The heat propagates better throughout the monolith due to the higher thermal conductivity of SiC compared to cordierite. In summary, SiC leads to a homogeneous heating of the entire catalyst material. The fact that dielectric losses of SiC decrease with temperature may help to self-limit the catalyst temperature

Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs

In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by acting on mitochondrial function, thereby heralding a life-saving path forward for patients suffering from neuroinflammatory diseases. Disorders of myelin in the nervous system damage the transmission of signals, resulting in loss of vision, motion, sensation, and other functions depending on the affected nerves, currently with no effective treatment. Klotho genes and their single-pass transmembrane Klotho proteins are powerful governors of the threads of life and death, true to the origin of their name, Fates, in Greek mythology. Among its many important functions, Klotho is an obligatory co-receptor that binds, activates, and/or potentiates critical fibroblast growth factor activity. Since the discovery of Klotho a little over two decades ago, it has become ever more apparent that when Klotho pathways go awry, oxidative stress and mitochondrial dysfunction take over, and age-related chronic disorders are likely to follow. The physiological consequences can be wide ranging, potentially wreaking havoc on the brain, eye, kidney, muscle, and more. Central nervous system disorders, neurodegenerative in nature, and especially those affecting the myelin sheath, represent worthy targets for advancing therapies that act upon Klotho pathways. Current drugs for these diseases, even therapeutics that are disease modifying rather than treating only the symptoms, leave much room for improvement. It is thus no wonder that this topic has caught the attention of biomedical researchers around the world.https://www.liebertpub.com/doi/10.1089/biores.2020.0004Published versio

Seroprevalence of Yersinia, Hepatitis E and Trichinella among migrant and nonmigrant populations in Berlin and Brandenburg (Germany)

Pork is a potential source of infection for Yersinia, Hepatitis E virus and Trichinella. In 2014, 2484 cases of yersiniosis, 671 hepatitis E cases and 1 trichinellosis case were reported in Germany. Although migrants represent 27% of Berlin inhabitants, data is lacking on subpopulation-specific exposure risks to zoonotic diseases. We aimed to estimate the seroprevalence and to identify potential risk factors for Yersinia, Hepatitis E and Trichinella in migrants and non-migrants in Berlin/Brandenburg

New Constraints on the Origin of the Short-Term Cyclical Variability of the Wolf-Rayet Star WR 46

The Wolf-Rayet star WR 46 is known to exhibit a very complex variability pattern on relatively short time scales of a few hours. Periodic but intermittent radial velocity shifts of optical lines as well as multiple photometric periods have been found in the past. Non-radial pulsations, rapid rotational modulation or the presence of a putative low-mass companion have been proposed to explain the short-term behaviour. In an effort to unveil its true nature, we observed WR 46 with FUSE (Far Ultraviolet Spectroscopic Explorer) over several short-term variability cycles. We found significant variations on a time scale of ~8 hours in the far-ultraviolet (FUV) continuum, in the blue edge of the absorption trough of the OVI {\lambda}{\lambda}1032, 1038 doublet P Cygni profile and in the SVI {\lambda}{\lambda}933, 944 P Cygni absorption profile. We complemented these observations with X-ray and UV light-curves and an X-ray spectrum from archival XMM-Newton (X-ray Multi-Mirror Mission - Newton Space Telescope) data. The X-ray and UV light-curves show variations on a time scale similar to the variability found in the FUV. We discuss our results in the context of the different scenarios suggested to explain the short-term variability of this object and reiterate that non-radial pulsations is the most likely to occur.Comment: 36 pages, 11 figures. Accepted for publication in Ap

Highly Ionized Collimated Outflow from HE 0238 - 1904

We present a detailed analysis of a highly ionized, multiphased and collimated outflowing gas detected through O V, O VI, Ne VIII and Mg X absorption associated with the QSO HE 0238 - 1904 (z_em ~ 0.629). Based on the similarities in the absorption line profiles and estimated covering fractions, we find that the O VI and Ne VIII absorption trace the same phase of the absorbing gas. Simple photoionization models can reproduce the observed N(Ne VIII), N(O VI) and N(Mg X) from a single phase whereas the low ionization species (e.g. N III, N IV, O IV) originate from a different phase. The measured N(Ne VIII)/N(O VI) ratio is found to be remarkably similar (within a factor of ~ 2) in several individual absorption components kinematically spread over ~ 1800 km/s. Under photoionization this requires a fine tuning between hydrogen density (nH) and the distance of the absorbing gas from the QSO. Alternatively this can also be explained by collisional ionization in hot gas with T > 10^{5.7} K. Long-term stability favors the absorbing gas being located outside the broad line region (BLR). We speculate that the collimated flow of such a hot gas could possibly be triggered by the radio jet interaction.Comment: Minor revision (accepted for publication in MNRAS letter

FUSE observations of the HI interstellar gas of IZw18

We present the analysis of FUSE observations of the metal-deficient dwarf galaxy IZw18. We measured column densities of HI, NI, OI, ArI, SiII, and FeII. The OI/HI ratio (log(OI/HI)=-4.7^{+0.8}_{-0.6}) is consistent with the O/H ratio observed in the HII regions (all uncertainties are 2-sigma). If the oxygen is depleted in the HI region compared to the HII regions, the depletion is at most 0.5dex. This is also consistent with the log(O/H) ratios ~-5 measured with FUSE in the HI regions of other blue compact dwarf galaxies. With log(NI/OI)=-2.4^{+0.6}_{-0.8}, the measured NI/OI ratio is lower than expected for primary nitrogen. The determination of the NII column density is needed to discriminate between a large ionization of NI or a possible nitrogen deficiency. The neutral argon is also apparently underabundant, indicating that ionization into ArII is likely important. The column densities of the other alpha-chain elements SiII and ArI favor the lower edge of the permitted range of OI column density, log(N(OI))~16.3.Comment: Accepted for publication in A&