Beef Heifers Performance under Continuous Grazing on Modified Grassland in Argentina Flooding Pampa

The Salado river basin is the main beef cattle breeding region of Argentina. It is a flat flooding area with poor slopes (\u3c 3%). Their soils are Natracuoles, Natraqualfes and Argiacuoles. The grasslands are predominately continuously grazed and with a set stocking rate cow – calf system. Stocking rate and grazing pressure are two core variables that directly affect animal production. Reduced animal performance is believed to be due to poor grazing management. During 2010, 2011 and 2012 an experiment on the effect of stocking rate on animal growth and body condition with Angus heifers continuously grazing annual winter grasses, was carried out. Previous studies have demonstrated the practicability of producing replacement females with this management (Carrillo 2001; Eirin et al. 2011; Agnelli et al. 2011) that involves mesothermic grasslands modification into self sown winter grasses by using glyphosate and other herbicides (Oyhamburu et al. 2000, Rodriguez and Jacobo 2010). The aim of this study was to establish the stocking rate that optimizes beef rearing heifer’s performance for early mating

Effects of Continuous Grazing and Exclusion on the Structure of Modified Flooding Pampa Grassland in Argentina

The breeding of beef cattle is the predominant activity in the Flooding Pampa wet grasslands. The stocking rate of this region is increasing because of livestock displaced by agriculture in other regions. This increased load has been achieved through the alteration of grassland with the use of herbicides and fertilizers or replacement thereof by pasture (Cahuepé and Hidalgo 2005). The large herbivores grazing cause changes in species composition and diversity (Hall et al. 1986) in both the original and the modified grassland. The aim of this study was to evaluate the effects of different stocking rates under continuous grazing and exclusion of grazing on the floristic composition and diversity of wet mesophytes prairie, modified during 10 years by the application of herbicides

Nasopharyngeal cancer in non-endemic areas: Impact of treatment intensity within a large retrospective multicentre cohort

Aim Recommendations for managing patients with nasopharyngeal carcinoma (NPC) in non-endemic areas are largely derived from studies conducted in endemic areas. We analysed the impact of treatment approaches on survival in non-endemic areas. Methods In an international, multicentre, retrospective study, we analyse consecutive patients with NPC diagnosed between 2004 and 2017 in 36 hospitals from 11 countries. Treatment was categorised as non-intensive (NIT), including radiotherapy alone or concomitant chemoradiotherapy (cCRT), and intensive (IT) including cCRT preceded by and/or followed by chemotherapy (CT). The impact of IT on overall survival (OS) and disease-free survival (DFS) was adjusted for all the available potential confounders. Results Overall, 1021 and 1113 patients were eligible for overall survival (OS) and disease-free survival (DFS) analyses, respectively; 501 and 554 with Epstein Barr-encoded RNA (EBER) status available. In the whole group, 5-year OS was 84% and DFS 65%. The use of NIT was associated with a risk of death or recurrence 1.37 times higher than patients receiving IT. Patients submitted to NIT and induction CT + concurrent concomitant chemo and three-dimensional Conformal Radiation Therapy (3DCRT) had a risk of death or recurrence 1.5 and 1.7 times higher than patients treated with induction CT + cCRT with intensity-modulated radiotherapy (IMRT), respectively. The IT had no impact on OS in neither patients with EBER+ nor in patients with EBER-; IT showed better DFS in EBER+ but not in patients with EBER-. Conclusions In low-incidence areas, patients with NPC treated with induction CT followed by concurrent IMRT cCRT achieved the highest DFS rate. The benefit of IT on DFS was restricted to patients with EBER+, suggesting that additional therapy offers no advantages in EBER- cases

Risk of Guillain-Barr\ue9 syndrome after 2010-2011 influenza vaccination

Influenza vaccination has been implicated in Guillain Barr\ue9 Syndrome (GBS) although the evidence for this link is controversial. A case-control study was conducted between October 2010 and May 2011 in seven Italian Regions to explore the relation between influenza vaccination and GBS. The study included 176 GBS incident cases aged 6518 years from 86 neurological centers. Controls were selected among patients admitted for acute conditions to the Emergency Department of the same hospital as cases. Each control was matched to a case by sex, age, Region and admission date. Two different analyses were conducted: a matched case-control analysis and a self-controlled case series analysis (SCCS). Case-control analysis included 140 cases matched to 308 controls. The adjusted matched odds ratio (OR) for GBS occurrence within 6 weeks after influenza vaccination was 3.8 (95 % CI: 1.3, 10.5). A much stronger association with gastrointestinal infections (OR = 23.8; 95 % CI 7.3, 77.6) and influenza-like illness or upper respiratory tract infections (OR = 11.5; 95 % CI 5.6, 23.5) was highlighted. The SCCS analysis included all 176 GBS cases. Influenza vaccination was associated with GBS, with a relative risk of 2.1 (95 % CI 1.1, 3.9). According to these results the attributable risk in adults ranges from two to five GBS cases per 1,000,000 vaccinations