45 research outputs found

    Thomas Berry on the rights of nature : evoking the Great Work

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    Paper presented at the Conference on Christian Perspectives on Human Dignity and Humans Rights held in Wuppertal (Germany) online from 9–12 April 202

    Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

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    Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe

    Robust estimation of bacterial cell count from optical density

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    Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

    Agama, filsafat, & lingkungan hidup.

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    Yogyakarta308 p.; 23 cm

    The Emerging Alliance of Religion and Ecology

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    Worldviews and ecology. : religion, philosoph, and the environment.

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    New York246 p.; 24 cm

    Living Within the Universe Story

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    The theme of Dr. Tucker’s talk is best captured by the words of Albert Einstein: “A human being is a part of a whole, called by us universe, a part limited in time and space. He experiences himself, his thoughts and feelings as something separated from the rest... a kind of optical delusion of his consciousness. This delusion is a kind of prison for us, restricting us to our personal desires and to affection for a few persons nearest to us. Our task must be to free ourselves from this prison by widening our circle of compassion to embrace all living creatures and the whole of nature in its beauty.” Dr. Tucker’s film and lecture presentations will offer a new perspective on the role of humans in the universe and will provoke important conversations about the ecological problems we face

    Keynote: Catholic Vision and Ecology

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    Mary Evelyn Tucker is a leading Catholic academic, researcher and spokesperson on religion and ecology. She focuses on the need for world’s religions to move from their theological and anthropological phase into their ecological and cosmological phase and become significant partners in identifying an ethical vision for sustainable life on the planet. “As the world’s religions suggest, our response to the earth is one of continued gratitude for the gift of life,” says Tucker. Tucker is co-founder of The Forum on Religion and Ecology, the largest international multireligious project of its kind. With conferences, publications and a website, it is engaged in exploring religious worldviews, texts, and ethics in order to broaden understanding of the complex nature of current environmental concerns.Currently visiting professor at Yale University, and research associate at the Harvard Yenching Institute, Tucker is author and/or co-editor of several books including Worldly Wonder: Religions Enter Their Ecological Phase, and Religion and Ecology: Can the Climate Change? Tucker is also a member of the Interfaith Partnership for the Environment at the United Nations Environment Programme and vice President of the American Teilhard Association. She was a member of the Earth Charter Drafting Committee and is currently a member of the Earth Charter International Council
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