Embedding clinical interventions into observational studies

Novel approaches to observational studies and clinical trials could improve the cost-effectiveness and speed of translation of research. Hybrid designs that combine elements of clinical trials with observational registries or cohort studies should be considered as part of a long-term strategy to transform clinical trials and epidemiology, adapting to the opportunities of big data and the challenges of constrained budgets. Important considerations include study aims, timing, breadth and depth of the existing infrastructure that can be leveraged, participant burden, likely participation rate and available sample size in the cohort, required sample size for the trial, and investigator expertise. Community engagement and stakeholder (including study participants) support are essential for these efforts to succeed

A Trickle‐Down Model Of Abusive Supervision

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91132/1/j.1744-6570.2012.01246.x.pd

Imported malaria in a cosmopolitan European city: A mirror image of the world epidemiological situation

© 2008 Millet et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

WHY EMPLOYEES DO BAD THINGS: MORAL DISENGAGEMENT AND UNETHICAL ORGANIZATIONAL BEHAVIOR

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90243/1/j.1744-6570.2011.01237.x.pd

An Integrative Approach to Understanding Counterproductive Work Behavior: The Roles of Stressors, Negative Emotions, and Moral Disengagement

Several scholars have highlighted the importance of examining moral disengagement (MD) in understanding aggression and deviant conduct across different contexts. The present study investigates the role of MD as a specific social-cognitive construct that, in the organizational context, may intervene in the process leading from stressors to counterproductive work behavior (CWB). Assuming the theoretical framework of the stressor-emotion model of CWB, we hypothesized that MD mediates, at least partially, the relation between negative emotions in reaction to perceived stressors and CWB by promoting or justifying aggressive responses to frustrating situations or events. In a sample of 1,147 Italian workers, we tested a structural equations model. The results support our hypothesis: the more workers experienced negative emotions in response to stressors, the more they morally disengaged and, in turn, enacted CW

A review of grout materials in geothermal energy applications

Ground heat exchangers are surrounded by grout material, making it one of the most important components in geothermal energy applications since it significantly affects the system's thermal performance. The current study reviews the different types of grout materials and compares their thermophysical properties. The most critical parameter is the grout's thermal conductivity in which it always presents a proportional relation with the system's efficiency. Numerous factors are involved in this review to ascertain theier impact on the grouts’ performance such as flowability, shrinkage, moisture content, freezing, heat capacity, strength, permeability, solubility and thermal imbalance. The different grouts compared are bentonite, cement, sand, graphite, controlled low-strength material, dolomite, and phase change materials. The literature shows that phase change materials are the best choices of grouting since they can provide high storage capacity, stability and temperature uniformity. The major problem of such materials is their low thermal conductivity. Thus, it is recommended to use composite phase change materials to enhance their thermal conductivity and increase the storage/retrieval rate