B=3 Tetrahedrally Symmetric Solitons in the Chiral Quark Soliton Model

In this paper, B=3 soliton solutions with tetrahedral symmetry are obtained numerically in the chiral quark soliton model using the rational map ansatz. The solution exhibits a triply degenerate bound spectrum of the quark orbits in the background of tetrahedrally symmetric pion field configuration. The corresponding baryon density is tetrahedral in shape. Our numerical technique is independent on the baryon number and its application to $B \geq 4$ is straightforward.Comment: 4 pages, 3 figure

On Size and Shape of the Average Meson Fields in the Semibosonized Nambu & Jona-Lasinio Model

We consider a two-flavor Nambu \& Jona-Lasinio model in Hartree approximation involving scalar-isoscalar and pseudoscalar-isovector quark-quark interactions. Average meson fields are defined by minimizing the effective Euklidean action. The fermionic part of the action, which contains the full Dirac sea, is regularized within Schwinger's proper-time scheme. The meson fields are restricted to the chiral circle and to hedgehog configurations. The only parameter of the model is the constituent quark mass $M$ which simultaneously controls the regularization. We evaluate meson and quark fields self-consistently in dependence on the constituent quark mass. It is shown that the self-consistent fields do practically not depend on the constituent quark mass. This allows us to define a properly parameterized reference field which for physically relevant constituent masses can be used as a good approximation to the exactly calculated one. The reference field is chosen to have correct behaviour for small and large radii. To test the agreement between self-consistent and reference fields we calculate several observables like nucleon energy, mean square radius, axial-vector constant and delta-nucleon mass splitting in dependence on the constituent quark mass. The agreement is found to be very well. Figures available on request.Comment: 12 pages (LATEX), 3 figures available on request, report FZR 93-1

Electromagnetic Form Factors of the SU(3) Octet Baryons in the semibosonized SU(3) Nambu-Jona-Lasinio Model

The electromagnetic form factors of the SU(3) octet baryons are investigated in the semibosonized SU(3) Nambu--Jona-Lasinio model (chiral quark-soliton model). The rotational $1/N_c$ and strange quark mass corrections in linear order are taken into account. The electromagnetic charge radii of the nucleon and magnetic moments are also evaluated. It turns out that the model is in a remarkable good agreement with the experimental data.Comment: RevTex is used. 37 pages. The final version to appear in Phys. Rev. D. 13 figures are include

Polarization degrees of freedom in photoinduced two-nucleon knockout from finite nuclei

The polarization degrees of freedom in photoinduced two-nucleon knockout from finite nuclei are studied. It is pointed out that they open good perspectives to study the dynamics of dinucleons in the medium in detail. The ($\gamma,pp$) and ($\gamma,pn$) angular cross sections, photon asymmetries and outgoing nucleon polarizations are calculated for the target nuclei $^{16}$O and $^{12}$C and photonenergies ranging from 100 up to 500 MeV. It is investigated to which degree the two-nucleon emission reaction is dominated by photoabsorption on $^3S_1(T=0)$ proton-neutron and $^1S_0(T=1)$ proton-proton pairs in the nuclear medium. The calculations demonstrate that dominance of $S$ wave photoabsorption in the ($\gamma,pn$) channel does not necessarily imply that the reaction mechanism is similar to what is observed in deuteron photodisintegration.Comment: 27 pages, REVTeX 3.0 with epsf.sty, 11 figures in EPS forma

Helicity skewed quark distributions of the nucleon and chiral symmetry

We compute the helicity skewed quark distributions $\widetilde{H}$ and $\widetilde{E}$ in the chiral quark-soliton model of the nucleon. This model emphasizes correctly the role of spontaneously broken chiral symmetry in structure of nucleon. It is based on the large-N_c picture of the nucleon as a soliton of the effective chiral lagrangian and allows to calculate the leading twist quark- and antiquark distributions at a low normalization point. We discuss the role of chiral symmetry in the helicity skewed quark distributions $\widetilde{H}$ and $\widetilde{E}$. We show that generalization of soft pion theorems, based on chiral Ward identities, leads in the region of -\xi < x < \xi to the pion pole contribution to $\widetilde{E}$ which dominates at small momentum transfer.Comment: 22 pages, 5 figure

Baryons as non-topological chiral solitons

The present review gives a survey of recent developments and applications of the Nambu--Jona-Lasinio model with $N_f=2$ and $N_f=3$ quark flavors for the structure of baryons. The model is an effective chiral quark theory which incorporates the SU(N$_f$)$_L\otimes$SU(N$_f$)$_R\otimes$U(1)$_V$ approximate symmetry of Quantum chromodynamics. The approach describes the spontaneous chiral symmetry breaking and dynamical quark mass generation. Mesons appear as quark-antiquark excitations and baryons arise as non-topological solitons with three valence quarks and a polarized Dirac sea. For the evaluation of the baryon properties the present review concentrates on the non-linear Nambu--Jona-Lasinio model with quark and Goldstone degrees of freedom which is identical to the Chiral quark soliton model obtained from the instanton liquid model of the QCD vacuum. In this non-linear model, a wide variety of observables of baryons of the octet and decuplet is considered. These include, in particular, electromagnetic, axial, pseudoscalar and pion nucleon form factors and the related static properties like magnetic moments, radii and coupling constants of the nucleon as well as the mass splittings and electromagnetic form factors of hyperons. Predictions are given for the strange form factors, the scalar form factor and the tensor charge of the nucleon.Comment: 104 pages, 27 figures as uuencoded and compressed postscript files , hardcopy available upon request; Prog.Part.Nucl.Phys. 37 (1996) (in print

Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine

In the field of predictive, preventive and personalised medicine, researchers are keen to identify novel and reliable ways to predict and diagnose disease, as well as to monitor patient response to therapeutic agents. In the last decade alone, the sensitivity of profiling technologies has undergone huge improvements in detection sensitivity, thus allowing quantification of minute samples, for example body fluids that were previously difficult to assay. As a consequence, there has been a huge increase in tear fluid investigation, predominantly in the field of ocular surface disease. As tears are a more accessible and less complex body fluid (than serum or plasma) and sampling is much less invasive, research is starting to focus on how disease processes affect the proteomic, lipidomic and metabolomic composition of the tear film. By determining compositional changes to tear profiles, crucial pathways in disease progression may be identified, allowing for more predictive and personalised therapy of the individual. This article will provide an overview of the various putative tear fluid biomarkers that have been identified to date, ranging from ocular surface disease and retinopathies to cancer and multiple sclerosis. Putative tear fluid biomarkers of ocular disorders, as well as the more recent field of systemic disease biomarkers, will be shown

Search for short baseline nu(e) disappearance with the T2K near detector

8 pages, 6 figures, submitted to PRD rapid communication8 pages, 6 figures, submitted to PRD rapid communicationWe thank the J-PARC staff for superb accelerator performance and the CERN NA61 collaboration for providing valuable particle production data. We acknowledge the support of MEXT, Japan; NSERC, NRC and CFI, Canada; Commissariat `a l’Energie Atomique and Centre National de la Recherche Scientifique–Institut National de Physique Nucle´aire et de Physique des Particules, France; DFG, Germany; INFN, Italy; National Science Centre (NCN), Poland; Russian Science Foundation, RFBR and Ministry of Education and Science, Russia; MINECO and European Regional Development Fund, Spain; Swiss National Science Foundation and State Secretariat for Education, Research and Innovation, Switzerland; STFC, UK; and DOE, USA. We also thank CERN for the UA1/NOMAD magnet, DESY for the HERA-B magnet mover system, NII for SINET4, the WestGrid and SciNet consortia in Compute Canada, GridPP, UK. In addition participation of individual researchers and institutions has been further supported by funds from ERC (FP7), EU; JSPS, Japan; Royal Society, UK; DOE Early Career program, USA

Meibum Lipid Composition in Asians with Dry Eye Disease

10.1371/journal.pone.0024339PLoS ONE610

Parkinson’s disease mouse models in translational research

Animal models with high predictive power are a prerequisite for translational research. The closer the similarity of a model to Parkinson’s disease (PD), the higher is the predictive value for clinical trials. An ideal PD model should present behavioral signs and pathology that resemble the human disease. The increasing understanding of PD stratification and etiology, however, complicates the choice of adequate animal models for preclinical studies. An ultimate mouse model, relevant to address all PD-related questions, is yet to be developed. However, many of the existing models are useful in answering specific questions. An appropriate model should be chosen after considering both the context of the research and the model properties. This review addresses the validity, strengths, and limitations of current PD mouse models for translational research