Galaxy and Mass Assembly (GAMA): Variation in Galaxy Structure Across the Green Valley

Using a sample of 472 local Universe (z < 0.06) galaxies in the stellar mass range 10.25 < log M*/MG < 10.75, we explore the variation in galaxy structure as a function of morphology and galaxy colour. Our sample of galaxies is sub-divided into red, green and blue colour groups and into elliptical and non-elliptical (disk-type) morphologies. Using KiDS and VIKING derived postage stamp images, a group of eight volunteers visually classified bars, rings, morphological lenses, tidal streams, shells and signs of merger activity for all systems. We find a significant surplus of rings (2.3σ) and lenses (2.9σ) in disk-type galaxies as they transition across the green valley. Combined, this implies a joint ring/lens green valley surplus significance of 3.3σ relative to equivalent disk-types within either the blue cloud or the red sequence. We recover a bar fraction of ∼ 44% which remains flat with colour, however, we find that the presence of a bar acts to modulate the incidence of rings and (to a lesser extent) lenses, with rings in barred disk-type galaxies more common by ∼ 20 − 30 percentage points relative to their unbarred counterparts, regardless of colour. Additionally, green valley disk-type galaxies with a bar exhibit a significant 3.0σ surplus of lenses relative to their blue/red analogues. The existence of such structures rules out violent transformative events as the primary end-of-life evolutionary mechanism, with a more passive scenario the favoured candidate for the majority of galaxies rapidly transitioning across the green valley. Key words: galaxies: elliptical and lenticular, cD – galaxies: spiral – galaxies: evo- lution – galaxies: star formation – galaxies: statistics – galaxies: structur

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts

COS 208-5 - The Environmental Data Science Innovation & Inclusion Lab (ESIIL): a next-generation NSF data synthesis center

The Environmental Data Science Innovation & Inclusion Lab (ESIIL) is a next-generation NSF synthesis center led by the University of Colorado Boulder in collaboration with NSF’s CyVerse at the University of Arizona and the University of Oslo. ESIIL enables a global community of environmental data scientists to leverage the wealth of environmental data and emerging analytics to develop science-based solutions to solve pressing challenges in biology and other environmental sciences. ESIIL holds inclusion as a core principle and method for diversifying environmental data science at a time when society needs all perspectives, and science needs to serve all. ESIIL’s research community generates discoveries and novel approaches through: 1) cutting-edge team science, 2) innovative tools and collaborative cyberinfrastructure, 3) data science education and training, and 4) inclusive participation and diverse groups. These activities advance the frontier of environmental data science, a rapidly evolving discipline bridging the computational, biological, environmental, and social sciences. ESIIL’s open Collaborative and Scalable Environment (CASE) cyberinfrastructure lowers barriers to scientific collaboration through tailored user experience, seamless connection to critical data sources, and premier cloud computing. ESIIL’s education program facilitates broad access to environmental data science skills and helps develop the next-generation data-capable workforce through our online learning portal, reaching over two million unique users each year. Partnerships with Tribal Colleges and Minority-Serving Institutions increase data skills and knowledge sharing among underrepresented groups. Join us in building the ESIIL Network, a diverse and inclusive community that is committed to generating data-inspired discoveries that enhance societal and ecosystem resilience.</p

Creating Inclusive Spaces for Earth and Environmental Data Science Education

This poster was presented by Dr. Elsa Culler at the 2023 ESA Conference.</p

Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation: A Report From the National Heart, Lung, and Blood Institute and the National Institutes of Health Office of the Director Workshop

This virtual workshop was convened by the National Heart, Lung, and Blood Institute, in partnership with the Office of Strategic Coordination of the Office of the National Institutes of Health Director, and held September 2 to 3, 2020. The intent was to assemble a multidisciplinary group of experts in basic, translational, and clinical research in neuroscience and cardiopulmonary disorders to identify knowledge gaps, guide future research efforts, and foster multidisciplinary collaborations pertaining to autonomic neural mechanisms of cardiopulmonary regulation. The group critically evaluated the current state of knowledge of the roles that the autonomic nervous system plays in regulation of cardiopulmonary function in health and in pathophysiology of arrhythmias, heart failure, sleep and circadian dysfunction, and breathing disorders. Opportunities to leverage the Common Fund's SPARC (Stimulating Peripheral Activity to Relieve Conditions) program were characterized as related to nonpharmacologic neuromodulation and device-based therapies. Common themes discussed include knowledge gaps, research priorities, and approaches to develop novel predictive markers of autonomic dysfunction. Approaches to precisely target neural pathophysiological mechanisms to herald new therapies for arrhythmias, heart failure, sleep and circadian rhythm physiology, and breathing disorders were also detailed