The Nebraska Natural Legacy Project: State Wildlife Action Plan 2nd edition

Nebraska’s rich biological diversity is composed of thousands of plant and animal species interacting with each other and the environment. The flora and fauna of the state, along with the natural habitats they occupy, form Nebraska’s natural heritage – a legacy that should be treasured just as much as our cultural heritage. Unfortunately, populations of many once common species have declined because of a variety of stresses, including habitat loss, habitat degradation, diseases, and competition and predation from invasive species. While conservation actions in the past have had notable successes, they have not been sufficient to stem the overall tide of species decline. There is a need for a comprehensive, systematic and proactive approach to conserving the full array of Nebraska’s biological diversity. The goals of the Nebraska Natural Legacy Project are to: 1. Reverse the decline of at-risk species (and avoid the need for state or federal listing as threatened or endangered) 2. Recover currently listed species and allow for their de-listing 3. Keep common species common 4. Conserve natural communities Almost all existing natural habitat in Nebraska, and the biological diversity it supports, resides on lands under private ownership. All Nebraskans can benefit from the strong conservation tradition and sound stewardship of private landowners. The Nebraska Natural Legacy Project seeks to continue this tradition, while at the same time creating new opportunities for collaboration between farmers, ranchers, communities, private and governmental organizations and others for conserving Nebraska’s biological diversity, our natural heritage. The Nebraska Natural Legacy Project is non-regulatory, voluntary, incentive-based conservation. As stewards for the next generation, it is everyone’s responsibility to ensure the treasures that were handed to us by nature and our predecessors are still here for future generations of Nebraskans to enjoy

The Fish Crow (\u3ci\u3eCorvus ossifragus\u3c/i\u3e) Reaches Nebraska

The Fish Crow (Corvus ossifragus) was formerly endemic to the southeastern United States where it inhabited coastal areas along the Atlantic and Gulf Coasts (McGowan 2001). Since the early 1900s, the species has steadily expanded north and west along major river systems (McGowan 2001). Fish Crow range expansion has followed a logical pattern, expanding along major rivers in regions close to established populations, in adjacent states to the south and east of Nebraska. The species was first recorded in Missouri in 1964 (Robbins and Easterla 1992). In 1984, Fish Crow was first reported in Kansas and by 1991 was found breeding in that state (Thomson and Ely 1992). Iowa\u27s first record was in 1991 (Kent and Dinsmore 1996). There are no records from adjacent states to the north and west of Nebraska (Tallman et al. 2002, Andrews and Righter 1992, Scott 1993, Wyoming Game and Fish Department 1997). The Fish Crow has long been considered an inevitable addition to Nebraska\u27s avifauna. During the summer of 2009, we observed an adult Fish Crow on multiple occasions on the lower Platte River (LPR) near its confluence with the Missouri River. Documentation was provided to the Nebraska Ornithologists\u27 Union Records Committee (NOURC) and this observation was subsequently accepted as the first documented record for the species in Nebraska (Mark Brogie, NOURC Chairperson, personal communication). Here, we describe our observations and comment on the future occurrence of the species in Nebraska

A Long-Term Vision for an Ecologically Sound Platte River

The Platte River extends about 310 mi (499 km) from North Platte, Nebraska, to its terminus at the Missouri River confluence near Plattsmouth, Nebraska. The Platte River Valley is a continentally significant ecosystem that serves as a major stopover for migratory waterbirds in the Central Flyway including the endangered Whooping Crane (Grus americana) and \u3e1 million Sandhill Cranes (Antigone canadensis) at the peak of spring migration. However, the Platte River Valley also supports a great diversity of avifauna including grassland breeding birds, native stream fish, vascular plants, herpetofauna, mammals, pollinators, and aquatic macroinvertebrates. Despite ongoing conservation efforts since the mid-1970s the ecosystem remains largely conservation dependent and an increasing number of species across taxa are being considered at risk of regional extirpation or outright extinction. However, given the attention provided to conservation in the Platte River Valley and the need to maintain ecologically functional stopover sites in the Central Flyway, there is a great opportunity to create a resilient refugium for biodiversity conservation in the central Great Plains. To that end we convened a working group of \u3e18 individuals representing \u3e9 organizations including representatives from non-profit conservation organizations, universities, and state and federal natural resource agencies to develop a long-term vision for an ecologically sound Platte River Valley (PRV). We met in groups of varying size for \u3e170 hours throughout a more than 3-year period and developed conservation priorities and objectives using a landscape design process. Landscape design is an interdisciplinary conservation planning process that incorporates components of landscape ecology and social dimensions of natural resources with the explicit intention of improving conservation implementation.https://digitalcommons.unl.edu/zeabook/1128/thumbnail.jp

The Nebraska Natural Legacy Project

When the Nebraska Game and Parks Commission began work on a comprehensive wildlife conservation strategy (Nebraska Natural Legacy Project) two and a half years ago, we had to decide on an approach that would ensure we developed the best plan possible. The agency could have drawn only from the expertise of professional biologists, or alternatively sought input from a wide diversity of stakeholders. We decided to utilize both and what resulted was one of the largest collaborative efforts ever undertaken on behalf of wildlife in the state’s history. Sixteen public input meetings, a conservation practitioners workshop, and dozens of meetings with the state’s biological experts and conservation and agricultural leaders has culminated in a proactive conservation plan that is based on the best available science and has a high probability for successful implementation

Landscape Vs. Local Habitat Scale Influences To Insect Communities From Tallgrass Prairie Remnants

Habitat loss and fragmentation currently threaten ecosystems worldwide, yet remain difficult to quantify because within-fragment habitat and landscape-scale influences often interact in unique ways. Although individual species respond to fragmentation differently, large-scale conservation planning must unavoidably target multiple species. Although information on a population’s response to fragmentation is critical, and measurements of species richness provide useful insights, exclusive reliance on these responses may mask important information about the taxonomic composition of assemblages in response to fragmentation. The North American tallgrass prairie ecosystem is one of the most threatened and fragmented ecosystems in the world, and insects are significant contributors to its biodiversity. In remaining grassland fragments, we evaluated within-fragment influences in conjunction with landscape-scale responses of representative insect communities from four feeding guilds: generalists, specialists, multiple life stage habitat use, and predators. Fragment-specific attributes capable of influencing insect diversity include plant species composition, plant biomass, abundance of blooming flowers, and vertical habitat heterogeneity created by the vegetation. Landscape-scale factors expected to influence patterns of insect species diversity include fragment size and shape as well as the spatial configuration of fragments. Ordination techniques were used to summarize composition of each feeding guild assemblage of each fragment, and structural equation modeling was used to examine the direct and indirect effects of fragmentation with influences from local habitats. Generalists (Orthoptera), mixed-modality feeding that changes with life stage (Lepidoptera), and specialist herbivores (Curculionidae) all responded directly to withinsite characterizations of the plant community. Site management from large ungulate grazing or mowing for hay production consistently had an indirect effect on the insect community through influences on plant community composition. The predator assemblage (Coccinellidae) was influenced directly by fragment shape. To maintain insect biodiversity in tallgrass prairie fragments, these results indicate that conservation practices should focus on communities in order to maintain insect biodiversity in tallgrass prairie fragments. Landscapescale factors must also be considered when making conservation decisions, primarily because predators (top trophic level organisms) are more likely to respond to regional changes

Alterations of liver mitochondrial bioenergetics in diabetic Goto-Kakizaki rats

Respiratory indexes and the transmembrane electrical potential ([Delta][Psi]) were evaluated in mitochondrial preparations from 6-month-old Goto-Kakizaki (GK) and Wistar rats in the presence of glutamate + malate and succinate. We found that in diabetic GK mitochondria, flavin adenine dinucleotide (FAD)-linked respiratory indexes (respiratory control ratio [RCR] and adenosine diphosphate [ADP] to oxygen ratio [ADP/O]) are increased and uncoupled respiration is largely enhanced, indicating increased respiratory chain activity in GK rats. [Delta][Psi] development in GK mitochondrial preparations, energized using glutamate + malate or succinate as substrates, and the repolarization rate upon phosphorylation of the added ADP were significantly higher in GK mitochondrial preparations. These results indicate an enhanced activity of the phosphorylation system, confirmed by evaluating [Delta][Psi] development when the mitochondria are energized by adenosine triphosphate (ATP). Moreover, recovery of the potential upon a phosphorylative cycle is increased in GK mitochondria, reflecting a more efficient coupling between the phosphorylative and oxidative system. Contrasting with results obtained for alloxan- or streptozotocin-induced diabetic rats, this study clearly demonstrates no impairment of mitochondrial bioenergetics in diabetic GK rats. On the contrary, at this age, we observed a higher efficiency of the phosphorylation system as compared with Wistar rats.http://www.sciencedirect.com/science/article/B6WN4-4D6XNW8-Y5/1/286fd1697cd262bccbc2e10cd0d2bdb

Dietary intake of flavonoids and oesophageal and gastric cancer: incidence and survival in the United States of America (USA)

BACKGROUND: Flavonoids, polyphenolic compounds concentrated in fruits and vegetables, have experimentally demonstrated chemopreventive effects against oesophageal and gastric cancer. Few epidemiologic studies have examined flavonoid intake and incidence of these cancers, and none have considered survival. METHODS: In this USA multicentre population-based study, case participants (diagnosed during 1993–1995 with oesophageal adenocarcinoma (OEA, n=274), gastric cardia adenocarcinoma (GCA, n=248), oesophageal squamous cell carcinoma (OES, n=191), and other gastric adenocarcinoma (OGA, n=341)) and frequency-matched controls (n=662) were interviewed. Food frequency questionnaire responses were linked with USDA Flavonoid Databases and available literature for six flavonoid classes and lignans. Case participants were followed until 2000 for vital status. Multivariable-adjusted odds ratios (ORs) and hazard ratios (HRs) (95% confidence intervals (CIs)) were estimated, comparing highest with lowest intake quartiles, using polytomous logistic and proportional hazards regressions, respectively. RESULTS: Little or no consistent association was found for total flavonoid intake (main population sources: black tea, orange/grapefruit juice, and wine) and incidence or survival for any tumour type. Intake of anthocyanidins, common in wine and fruit juice, was associated with a 57% reduction in the risk of incident OEA (OR=0.43, 95% CI=0.29–0.66) and OES (OR=0.43, 95% CI=0.26–0.70). The ORs for isoflavones, for which coffee was the main source, were increased for all tumours, except OES. Anthocyanidins were associated with decreased risk of mortality for GCA (HR=0.63, 95% CI=0.42–0.95) and modestly for OEA (HR=0.87, 95% CI=0.60–1.26), but CIs were wide. CONCLUSIONS: Our findings, if confirmed, suggest that increased dietary anthocyanidin intake may reduce incidence and improve survival for these cancers

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Targeted therapies and the consequent adoption of "personalized" oncology have achieved notable successes in some cancers; however, significant problems remain with this approach. Many targeted therapies are highly toxic, costs are extremely high, and most patients experience relapse after a few disease-free months. Relapses arise from genetic heterogeneity in tumors, which harbor therapy-resistant immortalized cells that have adopted alternate and compensatory pathways (i.e., pathways that are not reliant upon the same mechanisms as those which have been targeted). To address these limitations, an international task force of 180 scientists was assembled to explore the concept of a low-toxicity "broad-spectrum" therapeutic approach that could simultaneously target many key pathways and mechanisms. Using cancer hallmark phenotypes and the tumor microenvironment to account for the various aspects of relevant cancer biology, interdisciplinary teams reviewed each hallmark area and nominated a wide range of high-priority targets (74 in total) that could be modified to improve patient outcomes. For these targets, corresponding low-toxicity therapeutic approaches were then suggested, many of which were phytochemicals. Proposed actions on each target and all of the approaches were further reviewed for known effects on other hallmark areas and the tumor microenvironment. Potential contrary or procarcinogenic effects were found for 3.9% of the relationships between targets and hallmarks, and mixed evidence of complementary and contrary relationships was found for 7.1%. Approximately 67% of the relationships revealed potentially complementary effects, and the remainder had no known relationship. Among the approaches, 1.1% had contrary, 2.8% had mixed and 62.1% had complementary relationships. These results suggest that a broad-spectrum approach should be feasible from a safety standpoint. This novel approach has potential to be relatively inexpensive, it should help us address stages and types of cancer that lack conventional treatment, and it may reduce relapse risks. A proposed agenda for future research is offered.Multiple funders. See acknowledgments within article for details.This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.semcancer.2015.09.00