Instability of Supersonic Cold Streams Feeding Galaxies II. Nonlinear Evolution of Surface and Body Modes of Kelvin-Helmholtz Instability

As part of our long-term campaign to understand how cold streams feed massive galaxies at high redshift, we study the Kelvin-Helmholtz instability (KHI) of a supersonic, cold, dense gas stream as it penetrates through a hot, dilute circumgalactic medium (CGM). A linear analysis (Paper I) showed that, for realistic conditions, KHI may produce nonlinear perturbations to the stream during infall. Therefore, we proceed here to study the nonlinear stage of KHI, still limited to a two-dimensional slab with no radiative cooling or gravity. Using analytic models and numerical simulations, we examine stream breakup, deceleration and heating via surface modes and body modes. The relevant parameters are the density contrast between stream and CGM ($\delta$), the Mach number of the stream velocity with respect to the CGM ($M_{\rm b}$) and the stream radius relative to the halo virial radius ($R_{\rm s}/R_{\rm v}$). We find that sufficiently thin streams disintegrate prior to reaching the central galaxy. The condition for breakup ranges from $R_{\rm s} < 0.03 R_{\rm v}$ for $(M_{\rm b} \sim 0.75, \delta \sim 10)$ to $R_{\rm s} < 0.003 R_{\rm v}$ for $(M_{\rm b} \sim 2.25, \delta \sim 100)$. However, due to the large stream inertia, KHI has only a small effect on the stream inflow rate and a small contribution to heating and subsequent Lyman-$\alpha$ cooling emission.Comment: The main astrophysical results are Figure 22 and Figure 23. Final 7 pages are appendices. Accepted to MNRA

Computing Chevalley bases in small characteristics

Let L be the Lie algebra of a simple algebraic group defined over a field F and let H be a split Cartan subalgebra of L. Then L has a Chevalley basis with respect to H. If the characteristic of F is not 2 or 3, it is known how to find it. In this paper, we treat the remaining two characteristics. To this end, we present a few new methods, implemented in Magma, which vary from the computation of centralisers of one root space in another to the computation of a specific part of the Lie algebra of derivations of $L$.Comment: 22 page

Adhesion between cells, diffusion of growth factors, and elasticity of the AER produce the paddle shape of the chick limb

This paper has been withdrawnComment: This paper has been withdraw

Development and preliminary evaluation of the VPS ReplaySuite: a virtual double-headed microscope for pathology

BACKGROUND: Advances in computing and telecommunications have resulted in the availability of a range of online tools for use in pathology training and quality assurance. The majority focus on either enabling pathologists to examine and diagnose cases, or providing image archives that serve as reference material. Limited emphasis has been placed on analysing the diagnostic process used by pathologists to reach a diagnosis and using this as a resource for improving diagnostic performance. METHODS: The ReplaySuite is an online pathology software tool that presents archived virtual slide examinations to pathologists in an accessible video-like format, similar to observing examinations with a double-headed microscope. Delivered through a customised web browser, it utilises PHP (Hypertext PreProcessor) to interact with a remote database and retrieve data describing virtual slide examinations, performed using the Virtual Pathology Slide (VPS). To demonstrate the technology and conduct a preliminary evaluation of pathologists opinions on its potential application in pathology training and quality assurance, 70 pathologists were invited to use the application to review their own and other pathologists examinations of 10 needle-core breast biopsies and complete an electronic survey. 9 pathologists participated, and all subsequently completed an exit survey. RESULTS: Of those who replayed an examination by another pathologist, 83.3% (5/6) agreed that replays provided an insight into the examining pathologists diagnosis and 33.3% (2/6) reconsidered their own diagnosis for at least one case. Of those who reconsidered their original diagnosis, all re-classified either concordant with group consensus or original glass slide diagnosis. 77.7% (7/9) of all participants, and all 3 participants who replayed more than 10 examinations stated the ReplaySuite to be of some or great benefit in pathology training and quality assurance. CONCLUSION: Participants conclude the ReplaySuite to be of some or of great potential benefit to pathology training and quality assurance and consider the ReplaySuite to be beneficial in evaluating the diagnostic trace of an examination. The ReplaySuite removes temporal and spatial issues that surround the use of double-headed microscopes by allowing examinations to be reviewed at different times and in different locations to the original examination. While the evaluation set was limited and potentially subject to bias, the response of participants was favourable. Further work is planned to determine whether use of the ReplaySuite can result in improved diagnostic ability

The Fungal Cell Wall : Structure, Biosynthesis, and Function

N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M. are part of the MRC Centre for Medical Mycology. J.P.L. acknowledges support from ANR, Aviesan, and FRM.Peer reviewedPublisher PD

Modeling Methods for Discrete Choice Analysis

This paper introduces new forms, sampling and estimation approaches fordiscrete choice models. The new models include behavioral specifications oflatent class choice models, multinomial probit, hybrid logit, andnon-parametric methods. Recent contributions also include new specializedchoice based sample designs that permit greater efficiency in datacollection. Finally, the paper describes recent developments in the use ofsimulation methods for model estimation. These developments are designed toallow the applications of discrete choice models to a wider variety ofdiscrete choice problems.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47225/1/11002_2004_Article_138116.pd