Paradise Found? Black Gay Men in Atlanta: An Exploration of Community

This study examines the ways in which Black gay men in Atlanta create and experience community and culture every day, notwithstanding those discursive sources that situate life for Black gay men as particularly troubled. Drawing on ethnographic methods, including participant observation and interviewing, I attempt to show the complexity of Black gay men by exploring their world in Atlanta, Georgia, a city that has increasingly become known as a Black Gay Mecca. Qualitative research examining the ways Black gay men create and experience community has the potential to broaden academic discourses that have increasingly medicalized the Black gay male experience, and complicate popular social sentiment which (when recognizing the existence of Black gay men) often posits their life as one dimensional or dimensionless

Ocean FAIR Data Services

Well-founded data management systems are of vital importance for ocean observing systems as they ensure that essential data are not only collected but also retained and made accessible for analysis and application by current and future users. Effective data management requires collaboration across activities including observations, metadata and data assembly, quality assurance and control (QA/QC), and data publication that enables local and interoperable discovery and access and secures archiving that guarantees long-term preservation. To achieve this, data should be findable, accessible, interoperable, and reusable (FAIR). Here, we outline how these principles apply to ocean data and illustrate them with a few examples. In recent decades, ocean data managers, in close collaboration with international organizations, have played an active role in the improvement of environmental data standardization, accessibility, and interoperability through different projects, enhancing access to observation data at all stages of the data life cycle and fostering the development of integrated services targeted to research, regulatory, and operational users. As ocean observing systems evolve and an increasing number of autonomous platforms and sensors are deployed, the volume and variety of data increase dramatically. For instance, there are more than 70 data catalogs that contain metadata records for the polar oceans, a situation that makes comprehensive data discovery beyond the capacity of most researchers. To better serve research, operational, and commercial users, more efficient turnaround of quality data in known formats and made available through Web services is necessary. In particular, automation of data workflows will be critical to reduce friction throughout the data value chain. Adhering to the FAIR principles with free, timely, and unrestricted access to ocean observation data is beneficial for the originators, has obvious benefits for users, and is an essential foundation for the development of new services made possible with big data technologies

Black Queer TV: Reparative Viewing and the Sociopolitical Questions of Our Now

This dissertation is rooted in the general question: How do contemporary TV series featuring Black queer and trans representation highlight and address sociopolitical questions often found circulating within queer and cultural studies? Employing three programs, The Prancing Elites Project (2015), Empire (2015), and Pose (2018), this study argues that recent upticks in Black queer characters on TV provide room to move beyond traditional analyses often predicated on critical suspicion to instead engender readings revealing themes related to Black futurity, worldmaking, and coalition building, prominent topics within the fields of queer and cultural studies. Building from both Eve Kosofsky Sedgwick’s articulation of reparative reading and prior scholarship often critical of Black queer televisual representation, this dissertation’s interventions are both theoretical and methodological, presenting a recalibrated approach to gleaning the richness in Black queer media. Black Queer TV: Reparative Viewing and the Sociopolitical Questions of Our Now invigorates and broadens critical scholarship on media through nuancing programs depicting a range of Black queer people’s represented experiences

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other populations. Genome-wide association studies and subsequent meta-analyses of these two diseases as separate phenotypes have implicated previously unsuspected mechanisms, such as autophagy, in their pathogenesis and showed that some IBD loci are shared with other inflammatory diseases. Here we expand on the knowledge of relevant pathways by undertaking a meta-analysis of Crohn's disease and ulcerative colitis genome-wide association scans, followed by extensive validation of significant findings, with a combined total of more than 75,000 cases and controls. We identify 71 new associations, for a total of 163 IBD loci, that meet genome-wide significance thresholds. Most loci contribute to both phenotypes, and both directional (consistently favouring one allele over the course of human history) and balancing (favouring the retention of both alleles within populations) selection effects are evident. Many IBD loci are also implicated in other immune-mediated disorders, most notably with ankylosing spondylitis and psoriasis. We also observe considerable overlap between susceptibility loci for IBD and mycobacterial infection. Gene co-expression network analysis emphasizes this relationship, with pathways shared between host responses to mycobacteria and those predisposing to IBD