Fuel Cell as Range Extender in Battery Electric Vehicles for Supply Chain Fleets

The aim of this chapter is to present an outlook about implementation of a range extender system based on fuel cells for battery electric vehicles. Such a system is highly feasible to be implemented in electric vehicles, in particular those used by beverage industry in city centres. The tourism is another industry that uses electric vehicles, for instance in resorts, hotels, airports, zoos, etc. As well, public transportation is another sector involved with this vehicular technology. These sectors are all the time looking for high efficiency and low costs; however, they also need to extend the range of the vehicles to fulfill some logistics requirements in a route. This chapter presents a numerical example for illustrating an implementation of fuel cell range extender system. Advantages, disadvantages, and business opportunities in fuel cell technology are presented

Ebola virus disease 2014

Ebola virus disease was irst described in 1976 originating from the Ebola River in the Democratic Republic of Congo. Since then, Ebola virus has become an important public health threat in Africa, and now it is of great concern worldwide due to the recent outbreaks (9216 cases with 4555 deaths up to October 20th, 2014), and it is so far the largest and deadliest recorded in history. Five Ebola virus species have been identiied (including Zaire, Sudan, Ivory Coast, Reston, and Bundibugyo Ebola virus), and four of them have proved to be highly pathogenic for both human and non-human primates, causing viral hemorrhagic fever with case fatality rates of up to 90%, for which no approved therapeutics or vaccines are currently available. Ebola virus infections are characterized by immune suppression and a systemic inlammatory response that causes impairment of the vascular, coagulation, and immune systems, leading to multiorgan failure and shock, and thus, in some ways, resembling septic shock. The major affected countries, Sierra Leone, Guinea, Liberia, and Nigeria, have been struggling to contain and to mitigate the outbreak. Gene sequencing of the 2014 virus (2014WA) outbreak has demonstrated 98% homology with the Zaire Ebola virus, with a 49% case fatality ratio across the affected countries. In this review the characteristics of the viruses, pathogenesis, diagnosis, treatment, and the cases reported in health care workers (HCW) are described, as well as a summary of outbreaks of the virus since its discovery, including these last two outbreaks in Africa

O uso dos jogos virtuais de simulação no ensino-aprendizagem da contabilidade: revisão da literatura

Different professional educational careers —empirically dominant— are using simulation software to improve the hands-on-theoretical learning exercise of educational laboratories and experimental courses, under constructivist models to encourage active student participation. Research in different areas shows that simulators improve students’ educational processes and promote an interactive and playful space motivating learning. This research proposes to develop a review of literature to describe the maturity status of experiences in the application of accounting simulators in vocational education. The results found, show that the simulator application in accounting is in an emerging process. The research articles found on the application of simulation software strategies in accounting education confirm these results.Las distintas carreras educativas profesionales —con dominancia empírica— están utilizando software de simulación para mejorar el ejercicio de aprendizaje práctico-teórico de los laboratorios educativos y de los cursos experimentales, bajo modelos constructivistas para incentivar la participación activa de los estudiantes. Las investigaciones en distintas áreas comprueban que los simuladores mejoran los procesos educativos de los estudiantes y promueven un espacio interactivo y lúdico, motivando el aprendizaje. Esta investigación propone elaborar una revisión de la literatura para describir el estado de madurez de las experiencias en la aplicación de simuladores contables en la educación profesional. Los resultados encontrados muestran que la aplicación de simuladores en la contabilidad se encuentra en un estado emergente. Los artículos de investigación encontrados sobre la aplicación de estrategias de software de simulación en la educación contable confirman estos resultados.Os diferentes cursos de educação profissional — com dominância empírica — estão utilizando software de simulação para melhorar o exercício da aprendizagem prático-teórica dos laboratórios educacionais e dos cursos experimentais, sob modelos construtivistas para incentivar a participação dos estudantes. As pesquisas em diferentes áreas comprovam que os simuladores melhoram os processos educacionais dos estudantes e promovem um espaço interativo e lúdico, motivando a aprendizagem. Nesta pesquisa, propõe-se elaborar uma revisão da literatura para descrever o estado de maturidade das experiências na aplicação de simuladores contábeis na educação  profissional. Os resultados mostram que a aplicação de simuladores na contabilidade se encontra em um estado emergente. Os artigos de pesquisa encontrados sobre a aplicação de estratégias de software de simulação no ensino contábil confirmam esses resultados

Discusión sobre el espacio didáctico del laboratorio contable en la educación superior

En el campo de la contabilidad, el laboratorio contable ha ganado relevancia como un espacio para desarrollar competencias prácticas e investigativas de los estudiantes, fundamentales para su desempeño profesional. Sin embargo, es importante reflexionar sobre la naturaleza y objetivos de este laboratorio, evitando que se convierta en una práctica técnica. Este artículo se enfoca en analizar el papel del laboratorio contable y examinar su sentido en la formación de profesionales contables, así como revisar críticamente prácticas equivocadas en su implementación.  El artículo adopta un enfoque interpretativo, conceptual y reflexivo, buscando evaluar el propósito y la esencia del laboratorio contable, y proporcionar elementos conceptuales para reevaluar y mejorar su enseñanza. Se abordan temas como las diferencias desde la educación basada en competencia entre el espacio educativo de la educación tecnológica y profesional en contabilidad. Los resultados muestran las diferencias existentes en los espacios educativos de los laboratorios y talleres contables

Hábitos de leitura em inglês de professores bilíngues em formação

This paper shows the results of a research carried out at a university institution in Cartagena (Colombia), to analyze the reading habits in English of students in advanced semesters of a Bachelor's Degree in Bilingualism program. In this research, we used quantitative and qualitative data collection techniques (mixed approach) to determine what the reading habits of students in this program are like in English. According to the results, most of the students (78,6 %) are occasional readers, and only 9,2 % of them are frequent readers. Furthermore, reading is associated with academic obligations rather than an intrinsic motivation towards reading in a foreign language.Este artículo muestra los resultados de una investigación realizada en una institución universitaria de Cartagena (Colombia) con el fin de analizar los hábitos de lectura en inglés de los estudiantes de semestres avanzados de un programa de Licenciatura en Bilingüismo. En dicha investigación se recurrió a técnicas de recolección de datos cuantitativos y cualitativos (enfoque mixto) para determinar cómo es el hábito lector en inglés de los estudiantes de dicho programa. Según los resultados obtenidos, la mayoría de los estudiantes (78,6 %) son lectores ocasionales y tan solo el 9,2 % son lectores frecuentes; además, la lectura suele estar asociada a obligaciones de tipo académico más que a una motivación intrínseca hacia la lectura en lengua extranjera.Este artigo apresenta os resultados da pesquisa realizada em uma instituição universitária de Cartagena (Colômbia), com o objetivo de analisar os hábitos de leitura em inglês dos alunos do semestre avançado do curso de Bacharelado em Bilinguismo. Nesta pesquisa, recorreu-se a técnicas quantitativas e qualitativas de coleta de dados (abordagem mista) para determinar como é o hábito da leitura em inglês dos alunos deste programa. De acordo com os resultados obtidos, a maioria dos estudantes (78,6 %) são leitores ocasionais e apenas 9,2 % são leitores frequentes; Além disso, a leitura é geralmente associada a obrigações acadêmicas, e não a uma motivação intrínseca à leitura em uma língua estrangeira

Characteristics of patients with type 2 diabetes mellitus newly treated with GLP-1 receptor agonists (CHADIG Study): a cross-sectional multicentre study in Spain

Objective: Several glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1Ra) have been made recently available in Spain for type 2 diabetes mellitus (DM2) treatment. There are no published data on the clinical and sociodemographic profile of patients initiating treatment with GLP-1Ra in Spain. Our objective was to understand these patients' characteristics in a real-world clinical practice setting. Design: Cross-sectional observational study. Setting: Spanish specialist outpatient clinics. Participants: 403 adults with DM2 initiating GLP-1Ra treatment were included. Primary and secondary outcome measures: Sociodemographic and DM2-related clinical data, including treatment at and after GLP-1Ra initiation and comorbidities, were collected. Results: Evaluable patients (n=403; 50.9% female) were included ( July 2013 to March 2014) at 24 centres by 53 specialists (47 endocrinology, 6 internal medicine), with the following profile (value±SD): age (58.3±10.4 years), diabetes duration (9.9±7 years), body mass index (BMI; 36.2±5.5) and glycated haemoglobin (HbA1c; 8.4±1.4%); 14% had HbA1c≤7%. Previous antidiabetic treatment: 53.8% only oral antidiabetic drugs (OADs), 5.2% insulin and 40% insulin and OAD; of those receiving OAD, 35% single drug, 38.2% 2 drugs and 24% 3 drugs. Concomitant to GLP-1Ra, 55.3% were only on OAD, 36.2% on insulin and OAD, and 7.2% only on insulin. Of those receiving OAD, the GLP-1Ra was mainly associated with 1 drug (65%) or 2 drugs (31.8%). GLP-1Ra are frequently added to existing antidiabetic drugs, with dipeptidyl peptidase-4 inhibitors being the OAD most frequently switched (45% receiving 1 before starting GLP-1Ra, only 2.7% receiving it concomitantly). Conclusions: In Spain, GLP-1Ra therapy is usually started in combination with OADs or OADs and insulin. These drugs are used in relatively young patients often not reaching therapeutic goals with other treatment combinations, roughly a decade after diagnosis and with a relatively high BMI. The latter could be explaine

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL hypothesis

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis.info:eu-repo/semantics/publishedVersio

1er. Coloquio de educación para el diseño en la sociedad 5.0

Las memorias del 1er. Coloquio de Educación para el Diseño en la Sociedad 5.0 debenser entendidas como un esfuerzo colectivo de la comunidad de académicos de la División de Ciencias y Artes para el Diseño, que pone de manifiesto los retos y oportunidades que enfrenta la educación en diseño en un contexto de cambio acelerado y rompimiento de paradigmas.El evento se realizó el pasado mes de mayo de 2018 y se recibieron más de 50 ponencias por parte de las profesoras y profesores de la División.Las experiencias y/o propuestas innovadoras en cuanto a procesos de enseñanza y aprendizaje que presentan los autores en cada uno de sus textos son una invitación a reflexionar sobre nuestra situación actual en la materia, y emprender acciones en la División para continuar brindando una educación de calidad en diseño a nuestras alumnas, alumnos y la sociedad.Adicionalmente, se organizaron tres conferencias magistrales sobre la situación actual de la educación en Diseño y de las Instituciones de Educación Superior, impartidas por el Mtro. Luis Sarale, profesor de la Universidad Nacional de Cuyo en Mendoza (Argentina), y Presidente en su momento, de la Red de Carreras de Diseño en Universidades Públicas Latinoamericanas (DISUR), el Dr. Romualdo López Zárate, Rector de la Unidad Azcapotzalco, así como del Mtro. Luis Antonio Rivera Díaz, Jefe de Departamento de Teoría y Procesos del Diseño de la División de la Ciencias de la Comunicación y Diseño, en la Unidad Cuajimalpa de nuestra institución.La publicación de estas memorias son un esfuerzo divisional, organizado desde la Coordinación de Docencia Divisional y la Coordinación de Tecnologías del Aprendizaje, del Conocimiento y la Comunicación, para contribuir a los objetivos planteados en el documento ACCIONES:Agenda CyAD2021, en particular al eje de Innovación Educativa. Es necesario impulsar a todos los niveles de la División espacios de discusión orientados a reflexionar sobre el presente y futuro en la educación del diseñador, que contribuya a mejorar la calidad de la docencia y favorezca al fortalecimiento de los procesos de enseñanza y aprendizaje.Finalmente, extiendo un amplio reconocimiento a todos los miembros de la División que hicieron posible este evento, así como a todos los ponentes y participantes por compartir su conocimiento para que la División sea cada día mejor