21 research outputs found
Quantum privacy and quantum coherence
We derive a simple relation between a quantum channel's capacity to convey
coherent (quantum) information and its usefulness for quantum cryptography.Comment: 6 pages RevTex; two short comments added 7 October 199
Indeterminate-length quantum coding
The quantum analogues of classical variable-length codes are
indeterminate-length quantum codes, in which codewords may exist in
superpositions of different lengths. This paper explores some of their
properties. The length observable for such codes is governed by a quantum
version of the Kraft-McMillan inequality. Indeterminate-length quantum codes
also provide an alternate approach to quantum data compression.Comment: 32 page
Classical information deficit and monotonicity on local operations
We investigate classical information deficit: a candidate for measure of
classical correlations emerging from thermodynamical approach initiated in
[Phys. Rev. Lett 89, 180402]. It is defined as a difference between amount of
information that can be concentrated by use of LOCC and the information
contained in subsystems. We show nonintuitive fact, that one way version of
this quantity can increase under local operation, hence it does not possess
property required for a good measure of classical correlations. Recently it was
shown by Igor Devetak, that regularised version of this quantity is monotonic
under LO. In this context, our result implies that regularization plays a role
of "monotoniser".Comment: 6 pages, revte
On asymptotic continuity of functions of quantum states
A useful kind of continuity of quantum states functions in asymptotic regime
is so-called asymptotic continuity. In this paper we provide general tools for
checking if a function possesses this property. First we prove equivalence of
asymptotic continuity with so-called it robustness under admixture. This allows
us to show that relative entropy distance from a convex set including maximally
mixed state is asymptotically continuous. Subsequently, we consider it arrowing
- a way of building a new function out of a given one. The procedure originates
from constructions of intrinsic information and entanglement of formation. We
show that arrowing preserves asymptotic continuity for a class of functions
(so-called subextensive ones). The result is illustrated by means of several
examples.Comment: Minor corrections, version submitted for publicatio
Additivity and non-additivity of multipartite entanglement measures
We study the additivity property of three multipartite entanglement measures,
i.e. the geometric measure of entanglement (GM), the relative entropy of
entanglement and the logarithmic global robustness. First, we show the
additivity of GM of multipartite states with real and non-negative entries in
the computational basis. Many states of experimental and theoretical interests
have this property, e.g. Bell diagonal states, maximally correlated generalized
Bell diagonal states, generalized Dicke states, the Smolin state, and the
generalization of D\"{u}r's multipartite bound entangled states. We also prove
the additivity of other two measures for some of these examples. Second, we
show the non-additivity of GM of all antisymmetric states of three or more
parties, and provide a unified explanation of the non-additivity of the three
measures of the antisymmetric projector states. In particular, we derive
analytical formulae of the three measures of one copy and two copies of the
antisymmetric projector states respectively. Third, we show, with a statistical
approach, that almost all multipartite pure states with sufficiently large
number of parties are nearly maximally entangled with respect to GM and
relative entropy of entanglement. However, their GM is not strong additive;
what's more surprising, for generic pure states with real entries in the
computational basis, GM of one copy and two copies, respectively, are almost
equal. Hence, more states may be suitable for universal quantum computation, if
measurements can be performed on two copies of the resource states. We also
show that almost all multipartite pure states cannot be produced reversibly
with the combination multipartite GHZ states under asymptotic LOCC, unless
relative entropy of entanglement is non-additive for generic multipartite pure
states.Comment: 45 pages, 4 figures. Proposition 23 and Theorem 24 are revised by
correcting a minor error from Eq. (A.2), (A.3) and (A.4) in the published
version. The abstract, introduction, and summary are also revised. All other
conclusions are unchange
Spin and Rotations in Galois Field Quantum Mechanics
We discuss the properties of Galois Field Quantum Mechanics constructed on a
vector space over the finite Galois field GF(q). In particular, we look at
2-level systems analogous to spin, and discuss how SO(3) rotations could be
embodied in such a system. We also consider two-particle `spin' correlations
and show that the Clauser-Horne-Shimony-Holt (CHSH) inequality is nonetheless
not violated in this model.Comment: 21 pages, 11 pdf figures, LaTeX. Uses iopart.cls. Revised
introduction. Additional reference
Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks
Typically disease-causing CAG/CTG repeats expand, but rare affected families can display high levels of contraction of the expanded repeat amongst offspring. Understanding instability is important since arresting expansions or enhancing contractions could be clinically beneficial. The MutSβ mismatch repair complex is required for CAG/CTG expansions in mice and patients. Oddly, by unknown mechanisms MutSβ-deficient mice incur contractions instead of expansions. Replication using CTG or CAG as the lagging strand template is known to cause contractions or expansions respectively; however, the interplay between replication and repair leading to this instability remains unclear. Towards understanding how repeat contractions may arise, we performed in vitro SV40-mediated replication of repeat-containing plasmids in the presence or absence of mismatch repair. Specifically, we separated repair from replication: Replication mediated by MutSβ- and MutSα-deficient human cells or cell extracts produced slipped-DNA heteroduplexes in the contraction- but not expansion-biased replication direction. Replication in the presence of MutSβ disfavoured the retention of replication products harbouring slipped-DNA heteroduplexes. Post-replication repair of slipped-DNAs by MutSβ-proficient extracts eliminated slipped-DNAs. Thus, a MutSβ-deficiency likely enhances repeat contractions because MutSβ protects against contractions by repairing template strand slip-outs. Replication deficient in LigaseI or PCNA-interaction mutant LigaseI revealed slipped-DNA formation at lagging strands. Our results reveal that distinct mechanisms lead to expansions or contractions and support inhibition of MutSβ as a therapeutic strategy to enhance the contraction of expanded repeats
Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial
Background
Results of small trials indicate that fluoxetine might improve functional outcomes after stroke. The FOCUS trial aimed to provide a precise estimate of these effects.
Methods
FOCUS was a pragmatic, multicentre, parallel group, double-blind, randomised, placebo-controlled trial done at 103 hospitals in the UK. Patients were eligible if they were aged 18 years or older, had a clinical stroke diagnosis, were enrolled and randomly assigned between 2 days and 15 days after onset, and had focal neurological deficits. Patients were randomly allocated fluoxetine 20 mg or matching placebo orally once daily for 6 months via a web-based system by use of a minimisation algorithm. The primary outcome was functional status, measured with the modified Rankin Scale (mRS), at 6 months. Patients, carers, health-care staff, and the trial team were masked to treatment allocation. Functional status was assessed at 6 months and 12 months after randomisation. Patients were analysed according to their treatment allocation. This trial is registered with the ISRCTN registry, number ISRCTN83290762.
Findings
Between Sept 10, 2012, and March 31, 2017, 3127 patients were recruited. 1564 patients were allocated fluoxetine and 1563 allocated placebo. mRS data at 6 months were available for 1553 (99·3%) patients in each treatment group. The distribution across mRS categories at 6 months was similar in the fluoxetine and placebo groups (common odds ratio adjusted for minimisation variables 0·951 [95% CI 0·839–1·079]; p=0·439). Patients allocated fluoxetine were less likely than those allocated placebo to develop new depression by 6 months (210 [13·43%] patients vs 269 [17·21%]; difference 3·78% [95% CI 1·26–6·30]; p=0·0033), but they had more bone fractures (45 [2·88%] vs 23 [1·47%]; difference 1·41% [95% CI 0·38–2·43]; p=0·0070). There were no significant differences in any other event at 6 or 12 months.
Interpretation
Fluoxetine 20 mg given daily for 6 months after acute stroke does not seem to improve functional outcomes. Although the treatment reduced the occurrence of depression, it increased the frequency of bone fractures. These results do not support the routine use of fluoxetine either for the prevention of post-stroke depression or to promote recovery of function.
Funding
UK Stroke Association and NIHR Health Technology Assessment Programme