324 research outputs found

    Sacks: On Metaphor

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    Socialization Patterns and Children\u27s Television and Film-Related Play

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    Behavior Management Guide for Auburn Riverside High School

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    This project examined preventative and proactive behavior models and strategies that effect positive school climate and minimized misbehavior. The review of current research found that schools were more successful in reducing or eliminating violent behavior when a positive school-wide behavior program was developed with input from staff, students, community and parents and was frequently monitored and assessed over time. Included is a High School (9-12) Behavior Manual that focused on teaching good behavior and expectations and support for students using an in-school suspension model for students that need remediation. The overall purpose of this guide was to assist teachers and staff with the task of student discipline and school policies designed with that in mind

    On the Consequences of Television-Related Parent-Child Interaction

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    This is a theoretical examination of certain ways in which a child\u27s development may be affected by parent-child interactions in which the content of television programming appears as an explicit referent, i.e., as the topic of a verbal exchange, as the premise for a game, and so forth. The discussion deals with four areas of development, viz.: (1) the child\u27s interpretational skills with regard to the television medium; (2) the child\u27s repertory of cognitive categories regarding the real world; (3) the child\u27s behavioral repertory, including both verbal and nonverbal items; and (4) the child\u27s social relation¬ships. The paper concludes with a discussion of certain methodological issues involved in the empirical examination of these matters

    An Exploration of Sensory Features & their Relationship to Family Routines

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    Introduction: This study examined occupational engagement of families with children with ASD who have high sensory features in one of the two main subtype categories. High hyper-responsive group, High hypo-responsive group. Little research currently exists examining the ways that these divergent responses to sensation impact family occupations & routines. Research Aim: To describe the nature of relationships between specific sensory features and family occupations

    Quinones as dienophiles in the Diels-Alder reaction: history and applications in total synthesis

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    In the canon of reactions available to the organic chemist engaged in total synthesis, the Diels–Alder reaction is among the most powerful and well understood. Its ability to rapidly generate molecular complexity through the simultaneous formation of two carboncarbon bonds is almost unrivalled, and this is reflected in the great number of reported applications of this reaction. Historically, the use of quinones as dienophiles is highly significant, being the very first example investigated by Diels and Alder. Herein, we review the application of the Diels–Alder reaction of quinones in the total synthesis of natural products. The highlighted examples span some 60 years from the landmark syntheses of morphine (1952) and reserpine (1956) by Gates and Woodward, respectively, through to the present day examples, such as the tetracyclines

    Assessing the Impact of Field-of-Use Restrictions in Patent Licensing Agreements: The Ethical Pharmaceutical Industry in the United States, 1950–1962

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    [EN]There are a number of strategies employed by companies to limit price competition, including patenting. This article investigates patent licensing restrictions as a strategy to erode price competition, using mainly information gleaned from the 1960–1962 Kefauver Committee hearings. The article deals with the pharmaceutical industry, which is one of the few sectors in which patents are essential to the development and introduction of innovations. The current study adds to a body of literature that has yielded mixed results with respect to the role of patents in this industry. The main contribution of this research is that restrictive licensing clauses, specifically field-of-use restrictions, are found to be relevant in eroding price competition in the institutional market. However, in the retail ethical market, price competition was absent even when no field-of-use restrictions were included in licensing contracts, although product competition was relevant between patented drugs

    Multilayer nanoscale functionalization to treat disorders and enhance regeneration of bone tissue

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    The coatings application onto medical devices has experienced a continuous growth in the last few years. Medical device coating market is expected to grow at a CAGR of 5.16% to reach USD 10 million by 2023 due to the increasing geriatric population and the growing demand for continuous innovation. Layer-by-Layer (LbL) assembly represents a versatile method to modify the surface properties, in order to control cell interaction and thus enhance biological functions. Furthermore, LbL is environmentally friendly, able to coat all types of surfaces with the creation of homogenous film and to include and control the release of biomolecules/drugs. This feature review provides a critical overview on recent progresses in functionalizing materials by LbL assembly for bone regeneration and disorder treatment. An overview of emerging and visionary opportunities on LbL technologies and further combination with other existing methods used in biomedical field, is also discussed to evidence the new challenges and potential developments in bone regenerative medicine
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