701 research outputs found

    Individual Differences in Emotional Response to Music

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    Although emotional experiences with music have been enjoyed for millennia, research involving music has focused primarily on emotions perceived rather than felt, and not much research exists into differential emotional response to music as a function of individual differences. A recent study (Djikic, 2011) looked at the effect of music on personality, but it did not assess emotional state before or after listening. In an extension of that study, the present research explores how changes in emotion may be related to self-reported personality. Relationships between extraversion and neuroticism, emotional state before and after music listening, and liking the stimulus were examined. It was hypothesized that in predicting final emotional state, an interaction was expected between initial emotional state and liking the stimulus; personality was expected to moderate the relationship between liking the stimulus and its type; and greater change in affect would be found in music than in control conditions. A one-factor between-subjects experiment was conducted in which participants listened to one of four randomly-assigned sound conditions: choral music likely to be perceived as happy, instrumental music likely to be perceived as sad, Brownian noise, or a classroom lecture. Sixty students from a university located in the southeastern United States participated individually in a laboratory setting. Repeated measures assessed affect, extraversion and neuroticism, both before and after listening. Liking the stimulus was found to interact with initial negative affect in predicting negative affect after listening, but no similar interaction was found for positive affect. Highest levels of neuroticism were associated with liking the stimulus likely to be perceived as sad. Significantly greater reduction in negative affect was found in music conditions than control conditions. This study also found partial support for a surprising difference in neuroticism, which changed after exposure to all conditions except the Brownian noise control condition. These findings underscore the importance of individual differences in emotional response to music and the need to take them into account

    Consideration of urban green space in impact assessments for health

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    This paper explores how health aspects connected with the planning of urban green space are currently supported through two types of impact assessments: health impact assessment (HIA) and environmental assessment, including strategic environmental assessment (SEA) of policies, plans and programmes and environmental impact assessment (EIA) of projects. Seven HIAs and five EIAs/SEAs from the UK, the US, the Netherlands, Austria and Germany are reviewed, using an analytical framework designed on the basis of a literature review. An important finding is that whilst all HIAs follow a problem-/objectives-driven approach, designing guidelines for potential future projects, all EIAs/SEAs use an impact-driven approach, focusing on the impacts of planned and concrete action. HIAs therefore approach policy, plan, programme and project-making exercises from the outside, making suggestions to those working on them to consider certain aspects in the future, rather than working with them on improving things within a decision making process, as is usually is usually the case with EIAs/SEAs

    Single-nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands

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    The human adrenal gland is a complex endocrine tissue. Studies on adrenal renewal have been limited to animal models or human foetuses. Enhancing our understanding of adult human adrenal homeostasis is crucial for gaining insights into the pathogenesis of adrenal diseases, such as adrenocortical tumours. Here, we present a comprehensive cellular genomics analysis of the adult human normal adrenal gland, combining single-nuclei RNA sequencing and spatial transcriptome data to reconstruct adrenal gland homeostasis. As expected, we identified primary cells of the various zones of the adrenal cortex and medulla, but we also uncovered additional cell types. They constitute the adrenal microenvironment, including immune cells, mostly composed of a large population of M2 macrophages, and new cell populations, including different subpopulations of vascular-endothelial cells and cortical-neuroendocrine cells. Utilizing spatial transcriptome and pseudotime trajectory analysis, we support evidence of the centripetal dynamics of adrenocortical cell maintenance and the essential role played by Wnt/β-catenin, sonic hedgehog, and fibroblast growth factor pathways in the adult adrenocortical homeostasis. Furthermore, we compared single-nuclei transcriptional profiles obtained from six healthy adrenal glands and twelve adrenocortical adenomas. This analysis unveiled a notable heterogeneity in cell populations within the adenoma samples. In addition, we identified six distinct adenoma-specific clusters, each with varying distributions based on steroid profiles and tumour mutational status. Overall, our results provide novel insights into adrenal homeostasis and molecular mechanisms potentially underlying early adrenocortical tumorigenesis and/or autonomous steroid secretion. Our cell atlas represents a powerful resource to investigate other adrenal-related pathologies

    Silicon and Nickel Enrichment in Planet-Host Stars: Observations and Implications for the Core-Accretion Theory of Planet Formation

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    We present evidence that stars with planets exhibit statistically significant silicon and nickel enrichment over the general metal-rich population. We also present simulations which predict silicon enhancement of planet hosts within the context of the core-accretion hypothesis for giant planet formation. Because silicon and oxygen are both alpha elements, [Si/Fe] traces [O/Fe], so the silicon enhancement in planet hosts predicts that these stars are oxygen-rich as well. We present new numerical simulations of planet formation by core accretion that establish the timescale on which a Jovian planet reaches rapid gas accretion, t_rga, as a function of solid surface density sigma_solid: (t_rga / 1 Myr) = (sigma_solid / 25.0 g cm^{-2})^{-1.44}. This relation enables us to construct Monte Carlo simulations that predict the fraction of star-disk systems that form planets as a function of [Fe/H], [Si/Fe], disk mass, outer disk radius and disk lifetime. Our simulations reproduce both the known planet-metallicity correlation and the planet-silicon correlation reported in this paper. The simulations predict that 16% of Solar-type stars form Jupiter-mass planets, in agreement with 12% predicted from extrapolation of the observed planet frequency-semimajor axis distribution. Although a simple interpretation of core accretion predicts that the planet-silicon correlation should be much stronger than the planet-nickel correlation, we observe the same degree of silicon and nickel enhancement in planet hosts. If this result persists once more planets have been discovered, it might indicate a complexity in the chemistry of planet formation beyond the simple accumulation of solids in the core accretion theory.Comment: 45 pages, including 12 figures, accepted for publication in the Astrophysical Journa

    The development of a space climatology: 3. Models of the evolution of distributions of space weather variables with timescale

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    We study how the probability distribution functions of power input to the magnetosphere Pα and of the geomagnetic ap and Dst indices vary with averaging timescale, , between 3 hours and 1 year. From this we develop and present algorithms to empirically model the distributions for a given and a given annual mean value. We show that lognormal distributions work well for ap, but because of the spread of Dst for low activity conditions, the optimum formulation for Dst leads to distributions better described by something like the Weibull formulation. Annual means can be estimated using telescope observations of sunspots and modelling, and so this allows the distributions to be estimated at any given between 3 hour and 1 year for any of the past 400 years, which is another important step towards a useful space weather climatology. The algorithms apply to the core of the distributions and can be used to predict the occurrence rate of “large” events (in the top 5% of activity levels): they may contain some, albeit limited, information relevant to characterizing the much rarer “superstorm” events with extreme value statistics. The algorithm for the Dst index is the more complex one because, unlike ap, Dst can take on either sign and future improvements to it are suggested

    Engineers and planners: Sustainable water management alliances

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    Copyright © 2011 ICE Publishing Ltd. Permission is granted by ICE Publishing to print one copy for personal use. Any other use of these PDF files is subject to reprint fees.In the future, increasing pressure will inevitably be placed on the spatial planning system to improve its consideration of water management issues. Emerging challenges include designing for climatic extremes, reducing flood risk, managing increasingly scarce water resources and improving water quality. These issues need to be balanced with a range of other spatial planning priorities and objectives, including meeting new housing needs, facilitating economic growth, and creating and maintaining quality places. The sheer complexity of the issues surrounding water management and the impacts upon spatial planning mean that partnership working is essential to achieve an integrated approach. Planners need the expertise, and crucially the understanding, of engineers and hydrologists. However, there can be considerable misunderstanding and miscommunication between disciplines, often concerning the institutional context in which the various parties operate. A plethora of policies, tools and assessments exist, which can make integrated water management an overwhelming prospect for the planner. This paper attempts to identify and address some of the issues faced, as well as examining how planners embed hydrological issues in decision making and how engineers could better facilitate this

    Masses, radii, and orbits of small Kepler planets : The transition from gaseous to rocky planets

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    We report on the masses, sizes, and orbits of the planets orbiting 22 Kepler stars. There are 49 planet candidates around these stars, including 42 detected through transits and 7 revealed by precise Doppler measurements of the host stars. Based on an analysis of the Kepler brightness measurements, along with high-resolution imaging and spectroscopy, Doppler spectroscopy, and (for 11 stars) asteroseismology, we establish low false-positive probabilities (FPPs) for all of the transiting planets (41 of 42 have an FPP under 1%), and we constrain their sizes and masses. Most of the transiting planets are smaller than three times the size of Earth. For 16 planets, the Doppler signal was securely detected, providing a direct measurement of the planet's mass. For the other 26 planets we provide either marginal mass measurements or upper limits to their masses and densities; in many cases we can rule out a rocky composition. We identify six planets with densities above 5 g cm-3, suggesting a mostly rocky interior for them. Indeed, the only planets that are compatible with a purely rocky composition are smaller than 2 R ⊕. Larger planets evidently contain a larger fraction of low-density material (H, He, and H2O).Peer reviewedFinal Accepted Versio

    Animal-related factors associated with moderate-to-severe diarrhea in children younger than five years in western Kenya: A matched case-control study

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    Background Diarrheal disease remains among the leading causes of global mortality in children younger than 5 years. Exposure to domestic animals may be a risk factor for diarrheal disease. The objectives of this study were to identify animal-related exposures associated with cases of moderate-to-severe diarrhea (MSD) in children in rural western Kenya, and to identify the major zoonotic enteric pathogens present in domestic animals residing in the homesteads of case and control children. Methodology/Principal findings We characterized animal-related exposures in a subset of case and control children (n = 73 pairs matched on age, sex and location) with reported animal presence at home enrolled in the Global Enteric Multicenter Study in western Kenya, and analysed these for an association with MSD. We identified potentially zoonotic enteric pathogens in pooled fecal specimens collected from domestic animals resident at children’s homesteads. Variables that were associated with decreased risk of MSD were washing hands after animal contact (matched odds ratio [MOR] = 0.2; 95% CI 0.08–0.7), and presence of adult sheep that were not confined in a pen overnight (MOR = 0.1; 0.02–0.5). Variables that were associated with increased risk of MSD were increasing number of sheep owned (MOR = 1.2; 1.0–1.5), frequent observation of fresh rodent excreta (feces/urine) outside the house (MOR = 7.5; 1.5–37.2), and participation of the child in providing water to chickens (MOR = 3.8; 1.2–12.2). Of 691 pooled specimens collected from 2,174 domestic animals, 159 pools (23%) tested positive for one or more potentially zoonotic enteric pathogens (Campylobacter jejuni, C. coli, non-typhoidal Salmonella, diarrheagenic E. coli, Giardia, Cryptosporidium, or rotavirus). We did not find any association between the presence of particular pathogens in household animals, and MSD in children. Conclusions and significance Public health agencies should continue to promote frequent hand washing, including after animal contact, to reduce the risk of MSD. Future studies should address specific causal relations of MSD with sheep and chicken husbandry practices, and with the presence of rodents
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