11 research outputs found
Incorporação da responsabilidade social empresarial em decisões de investimento utilizando técnicas multi-critérios
La Responsabilidad Social Empresaria (RSE) se ha convertido en un aspectomás a analizar a la hora de tomar decisiones de inversión. En este sentido, lasempresas deben informar sobre su desempeño general no sólo en su dimensióneconómica y financiera sino también en lo referente a los aspectos referidosal gobierno corporativo, social y medioambiental. Sin embargo, tanto lacantidad como la calidad de la información brindada en los reportes sobreRSE que brindan las empresas es variada, y los criterios para elaborarlos nosiempre coinciden. Entonces, cabe preguntarnos ¿Cuáles son los aspectosde interés que tiene en cuenta un inversor argentino?En este trabajo se utilizaron los indicadores más relevantes tanto paralas empresas como para los grupos de interés para medir la importanciade la RSE en diferentes sectores de la economía. Para ello se trabajó conla técnica de decisión multicriterio, llamada proceso analítico jerárquico oanalytic hierarchy process (AHP), tomando como base los principales indicadoresestándares que pueden aplicarse en Argentina y usando la informaciónobtenida a través de encuestas a dos grupos de interés diferentes.Esto permitió estructurar el problema en niveles de diferente jerarquía.Al comparar los resultados obtenidos con la aplicación de la metodologíaAHP desarrollada, se visualiza que el orden de preferencia en lasalternativas difiere del establecido de acuerdo con el volumen negociadoen el mercado de capitales. El sector financiero, considerado como uno delos ejes del desarrollo de la economía del país, ha demostrado un ciertogrado de avance en cuanto a prácticas de responsabilidad social. Estose vio reflejado en los resultados obtenidos, donde un mayor compromisoformal de las empresas de este sector en prácticas de RSE quedaen evidencia. Sin embargo, es necesario continuar con esta política desustentabilidad, involucrándose en proyectos que contribuyan al bienestarde la población.http://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/CE/article/view/7238/10467publishedVersionFil: Bravino, Laura Susana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Margaría, Oscar Alcides. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Rojas Heredia, Elena. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Santillán, Gustavo Alejandro. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Rosset, Cecilia Verónica. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Negocios y Administració
Agendas de género y discurso de las organizaciones internacionales en América Latina
Desde los años noventa del siglo pasado, la presencia de mujeres en instancias de gobierno, y en puestos de relevancia en las organizaciones internacionales, ha supuesto un aumento en la calidad de la representación de los regímenes democráticos a nivel interno, y una gradual modificación en los discursos, en las prácticas y en las culturas organizacionales de las instancias multilaterales, a nivel internacional. La investigación que presentamos se propone analizar la emergencia de la cuestión de género en la agenda de las organizaciones internacionales, la redefinición del discurso de estos organismos en función de este nuevo elemento, y cómo y en qué medida estas redefiniciones responden a las transformaciones impulsadas por la introducción de la cuestión de género en la vida política de América LatinaFil: Specchia, Nelson Gustavo. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; ArgentinaFil: Camps, Hernán Ramiro. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; ArgentinaFil: Imhof, Lelia. Universidad Católica de Córdoba. Facultad de Ciencias Agropecuarias; Argentin
Ciencia Odontológica 2.0
Libro que muestra avances de la Investigación Odontológica en MéxicoEs para los integrantes de la Red de Investigación en Estomatología (RIE) una enorme alegría presentar el segundo de una serie de 6 libros sobre casos clínicos, revisiones de la literatura e investigaciones. La RIE está integrada por cuerpos académicos de la UAEH, UAEM, UAC y UdeG
Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences
The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported
by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on
18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based
researchers who signed it in the short time span from 20 September to 6 October 2016
Mis casos clínicos de especialidades odontológicas
Libro que muestra la atención de casos clínicos particulares referente a las diferentes especialidades odontológicasLibro que muestra la atención de casos clínicos particulares referente a las diferentes especialidades odontológicasUniversidad Autónoma de Campeche
Universidad Autónoma del Estado de Hidalgo
Universidad Autónoma del Estado de Méxic
The Argentine foreign policy towards the southeast of Asia between the presidential periods of Carlos Nemen and Nestor Kirchner from a constructive look
The importance gained by Southeast Asian countries as emerging economies since the nineties has converted their markets in significant targets for Argentinean exports. Our aim in this paper is to identify the characteristics of the relation between Argentina and its main trade partners in Southeast Asia since 1989. In order to achieve this goal we will analyze the commercial and also the political dimensions. Our interest is to define if the trade relation was accompanied by an attempt of political rapprochement, and if the trade increase can be understood as a part of an Argentinean foreign policy towards diversification.</p
Características clínico-epidemiológicas y predictores de complicaciones coronarias en niños de Argentina con enfermedad de Kawasaki
Interim safety and immunogenicity results from an NDV-based COVID-19 vaccine phase I trial in Mexico
Abstract There is still a need for safe, efficient, and low-cost coronavirus disease 2019 (COVID-19) vaccines that can stop transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here we evaluated a vaccine candidate based on a live recombinant Newcastle disease virus (NDV) that expresses a stable version of the spike protein in infected cells as well as on the surface of the viral particle (AVX/COVID-12-HEXAPRO, also known as NDV-HXP-S). This vaccine candidate can be grown in embryonated eggs at a low cost, similar to influenza virus vaccines, and it can also be administered intranasally, potentially to induce mucosal immunity. We evaluated this vaccine candidate in prime-boost regimens via intramuscular, intranasal, or intranasal followed by intramuscular routes in an open-label non-randomized non-placebo-controlled phase I clinical trial in Mexico in 91 volunteers. The primary objective of the trial was to assess vaccine safety, and the secondary objective was to determine the immunogenicity of the different vaccine regimens. In the interim analysis reported here, the vaccine was found to be safe, and the higher doses tested were found to be immunogenic when given intramuscularly or intranasally followed by intramuscular administration, providing the basis for further clinical development of the vaccine candidate. The study is registered under ClinicalTrials.gov identifier NCT04871737
DataSheet_1_NK cells with decreased expression of multiple activating receptors is a dominant phenotype in pediatric patients with acute lymphoblastic leukemia.pdf
NK cells have unique attributes to react towards cells undergoing malignant transformation or viral infection. This reactivity is regulated by activating or inhibitory germline encoded receptors. An impaired NK cell function may result from an aberrant expression of such receptors, a condition often seen in patients with hematological cancers. Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer worldwide and NK cells have emerged as crucial targets for developing immunotherapies. However, there are important gaps concerning the phenotype and behavior of NK cells during emergence of ALL. In this study we analyze the phenotype and function of NK cells from peripheral blood in pediatric patients with ALL at diagnosis. Our results showed that NK cells exhibited an altered phenotype highlighted by a significant reduction in the overall expression and percent representation of activating receptors compared to age-matched controls. No significant differences were found for the expression of inhibitory receptors. Moreover, NK cells with a concurrent reduced expression in various activating receptors, was the dominant phenotype among patients. An alteration in the relative frequencies of NK cells expressing NKG2A and CD57 within the mature NK cell pool was also observed. In addition, NK cells from patients displayed a significant reduction in the ability to sustain antibody-dependent cellular cytotoxicity (ADCC). Finally, an aberrant expression of activating receptors is associated with the phenomenon of leukemia during childhood.</p
DataSheet_2_NK cells with decreased expression of multiple activating receptors is a dominant phenotype in pediatric patients with acute lymphoblastic leukemia.docx
NK cells have unique attributes to react towards cells undergoing malignant transformation or viral infection. This reactivity is regulated by activating or inhibitory germline encoded receptors. An impaired NK cell function may result from an aberrant expression of such receptors, a condition often seen in patients with hematological cancers. Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer worldwide and NK cells have emerged as crucial targets for developing immunotherapies. However, there are important gaps concerning the phenotype and behavior of NK cells during emergence of ALL. In this study we analyze the phenotype and function of NK cells from peripheral blood in pediatric patients with ALL at diagnosis. Our results showed that NK cells exhibited an altered phenotype highlighted by a significant reduction in the overall expression and percent representation of activating receptors compared to age-matched controls. No significant differences were found for the expression of inhibitory receptors. Moreover, NK cells with a concurrent reduced expression in various activating receptors, was the dominant phenotype among patients. An alteration in the relative frequencies of NK cells expressing NKG2A and CD57 within the mature NK cell pool was also observed. In addition, NK cells from patients displayed a significant reduction in the ability to sustain antibody-dependent cellular cytotoxicity (ADCC). Finally, an aberrant expression of activating receptors is associated with the phenomenon of leukemia during childhood.</p