165 research outputs found

    Diversity and Polarization of Research Performance: Evidence from Hungary

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    Measuring the intellectual diversity encoded in publication records as a proxy to the degree of interdisciplinarity has recently received considerable attention in the science mapping community. The present paper draws upon the use of the Stirling index as a diversity measure applied to a network model (customized science map) of research profiles, proposed by several authors. A modified version of the index is used and compared with the previous versions on a sample data set in order to rank top Hungarian research organizations (HROs) according to their research performance diversity. Results, unexpected in several respects, show that the modified index is a candidate for measuring the degree of polarization of a research profile. The study also points towards a possible typology of publication portfolios that instantiate different types of diversity

    Bio-inspired Methods for Dynamic Network Analysis in Science Mapping

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    We apply bio-inspired methods for the analysis of different dynamic bibliometric networks (linking papers by citation, authors, and keywords, respectively). Biological species are clusters of individuals defined by widely different criteria and in the biological perspective it is natural to (1) use different categorizations on the same entities (2) to compare the different categorizations and to analyze the dissimilarities, especially as they change over time. We employ the same methodology to comparisons of bibliometric classifications. We constructed them as analogs of three species concepts: cladistic or lineage based, similarity based, and "biological species" (based on co-reproductive ability). We use the Rand and Jaccard indexes to compare classifications in different time intervals. The experiment is aimed to address the classic problem of science mapping, as to what extent the various techniques based on different bibliometric indicators, such as citations, keywords or authors are able to detect convergent structures in the litrerature, that is, to identify coherent specialities or research directions and their dynamics

    Increased Production of the Soluble Tumor-Associated Antigens CA19-9, CA125, and CA15-3 in Rheumatoid Arthritis

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    Some tumor-associated antigens (TAAs) are expressed on inflammatory cells. We previously detected carcinoembryonic antigen (CEA; CD66) in the rheumatoid (RA) synovium. The production of CEA, CA19-9, CA125, and CA15.3, may be increased in patients with RA, scleroderma, lupus, and SjÖgren's syndrome (SS). Some of these TAAs contain sialylated carbohydrate motifs and they are involved in tumor-associated cell adhesion and metastasis. We assessed levels of TAAs in the sera of RA patients and healthy subjects. Serum TAA levels were correlated with disease markers including serum rheumatoid factor (RF), C-reactive protein (CRP), and anti-CCP antibody levels, DAS28, age disease duration. TAAs including CEA, CA15-3, CA72-4, CA125, and CA19-9, and neuron-specific enolase (NSE) were assessed by immunoassay in the sera of 75 patients with RA and 50 age- and sex-matched healthy controls. Normal upper limits for these TAAs were 3.4 Μg/L, 25 kU/L, 6.9 kU/L, 35 kU/L, 34 kU/L, and 16.3 Μg/L, respectively. There were significantly more RA patients showing abnormally high levels of CA125 (10.8% versus 7.1%), CA19-9 (8.1% versus 0%), and CA15-3 (17.6% versus 14.3%) in comparison to controls ( P < 0.05). The mean absolute serum levels of CA125 (23.9 ± 1.8 versus 16.8 ± 2.2 kU/L) and CA19-9 (14.2 ± 1.2 versus 10.5 ± 1.6 kU/L) were also significantly higher in RA compared to controls ( P < 0.05). Among RA patients, serum CEA showed significant correlation with RF ( r = 0.270; P < 0.05). None of the assessed TAAs showed any correlation with CRP, anti-CCP, DAS28, age or disease duration. The concentration of some TAAs may be elevated in the sera of patients with established RA in comparison to healthy subjects. CEA, CA19-9, CA125, and CA15-3 contain carbohydrate motifs and thus they may be involved in synovitis-associated adhesive events. Furthermore, some TAAs, such as CEA, may also correlate with prognostic factors, such as serum RF levels.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73224/1/annals.1422.037.pd

    Effective Rheology of Bubbles Moving in a Capillary Tube

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    We calculate the average volumetric flux versus pressure drop of bubbles moving in a single capillary tube with varying diameter, finding a square-root relation from mapping the flow equations onto that of a driven overdamped pendulum. The calculation is based on a derivation of the equation of motion of a bubble train from considering the capillary forces and the entropy production associated with the viscous flow. We also calculate the configurational probability of the positions of the bubbles.Comment: 4 pages, 1 figur

    Alignment of the ALICE Inner Tracking System with cosmic-ray tracks

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    37 pages, 15 figures, revised version, accepted by JINSTALICE (A Large Ion Collider Experiment) is the LHC (Large Hadron Collider) experiment devoted to investigating the strongly interacting matter created in nucleus-nucleus collisions at the LHC energies. The ALICE ITS, Inner Tracking System, consists of six cylindrical layers of silicon detectors with three different technologies; in the outward direction: two layers of pixel detectors, two layers each of drift, and strip detectors. The number of parameters to be determined in the spatial alignment of the 2198 sensor modules of the ITS is about 13,000. The target alignment precision is well below 10 micron in some cases (pixels). The sources of alignment information include survey measurements, and the reconstructed tracks from cosmic rays and from proton-proton collisions. The main track-based alignment method uses the Millepede global approach. An iterative local method was developed and used as well. We present the results obtained for the ITS alignment using about 10^5 charged tracks from cosmic rays that have been collected during summer 2008, with the ALICE solenoidal magnet switched off.Peer reviewe

    Centrality Dependence Of The Pseudorapidity Density Distribution For Charged Particles In Pb-pb Collisions At √snn=2.76tev

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    7264/Mai61062

    Long-range Angular Correlations On The Near And Away Side In P-pb Collisions At √snn=5.02 Tev

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    7191/Mar294

    Long-range angular correlations on the near and away side in p&#8211;Pb collisions at

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