CALIDAD DE VIDA, SALUD Y TRABAJO, LA RELACIÓN CON DIABETES MELLITUS TIPO 2

Comparar la Calidad de Vida (CV), la percepción de su salud y su relación con el trabajo en personas con y sin diagnóstico de diabetes. Estudio transversal comparativo, la muestra fue determinada por el total de pacientes con diagnostico de diabetes que asistieron en un periodo de 6 meses a 3 centros de salud mayores de 40 años, usuarios del sistema público de salud. Para CV, aplicamos EuroQol-5D con 5 dimensiones, además variables sociodemográficas, los datos se procesaron con programa SPSS 11.0, aplicando Chi2, análisis de varianza y razónde momios, tomando como significativa una P <0.05. Del total de la muestra (238), el 61 % son mujeres, con edad promedio de 54.7± 6.8 años, el 47 % dedicados a labores domésticas, un 38 % con estudio superiores a primaria, 23 % sin primaria y 39 % con primaria terminada, al separar entre diabéticos y no diabéticos no existieron diferencias en las variables sociodemográficas de sexo, escolaridad y estado civil, a excepción de la remuneración económica (p=0.002) y esta a la vez de promedio de edad (0.002). En las 5 dimensiones y en la calificación global de CV, el puntaje fue mayor para las personas sin diabetes quienes se autocalifican con una mejor calidad de vida, el área más afectada en las personas con diabetes es ansiedad/depresión (P<0.00). Existe tendencia a que las mujeres con diabetes califiquen más alta su CV en comparación con los hombres. Las personas con diabetes califican como más deteriorada su calidad de vida, aunque existe una tendencia favorable en las mujeres con diabetes, quienes evalúan como mejor su calidad de vida en relación a los hombres con diabetes. La dimensión más afectada es ansiedad/depresión. AbstractCompare the quality of life (QoL), perception of health and its relation in people with and without diabetes. Study comparative sample of 208 people over 40 years, users of the public health system. For QoL, we apply 5 EuroQol-5D dimensions, besides sociodemographic variables, the data were processed with SPSS 11.0 program using Chi2 analysis of variance and odds ratios, taking as a significant P <0.05. The total sample (238), 61% are women, with an average age of 54.7 ± 6.8 years, 47% devoted to housework, 38% with higher education to primary, 23% without primary and 39% Primary completed, the separation between diabetics and nondiabetics, there were no differences in sociodemographic variables of gender, education and marital status, with the exception of financial compensation (p = 0.002) and this time the average age (0.002). In 5 dimensions and the overall rating of CV, the score was higher for people without diabetes who self rated with a better quality of life, the area most affected in people with diabetes is anxiety / depression (P <0.00). There was a tendency for women with diabetes to qualify higher CV compared with men. People with diabetes are classified as deteriorating quality of life, although there is a favorable trend in women with diabetes who evaluate and improve their quality of life compared to men with diabetes. The most affected dimension is anxiety / depression. Palabras clave: Diabetes Mellitus tipo 2, Calidad de Vida, Salud, Trabajo

Diabetes tipo 2 y depresión en guadalajara, méxico. 2005

Objetivo Determinar la prevalencia de depresión y comparar indicadoressociodemográficos, metabólicos y clínicos, en personas con diabetes tipo 2deprimidas y no deprimidas.Material y Métodos Se realizó un estudio transversal comparativo en una muestrade 450 personas con diabetes tipo 2, mayores de 30 años, con más de un año dediagnóstico y sin determinación de psicopatología. Aplicamos escala de Zungmodificada y encuesta sociodemográfica, evaluamos Hemoglobina glucosilada,índice de masa corporal (IMC), tensión arterial y glucemia de ayuno; registramosantigüedad diagnóstica y estadio clínico de diabetes.Resultados La prevalencia de depresión fue de 63 %, en una proporción de 3 a 1,mayor en mujeres que en hombres con razón de momios 3,17(IC 95 % 2,08-4,82)p=0,0000. Existen diferencias en escolaridad, estado civil y ocupación entredeprimidos y no deprimidos (p and lt;0.05), la edad no presenta diferencias, al igual quelas variables metabólicas, excepto IMC, antigüedad diagnóstica y estadio clínico 3y 4. En las variables socio-demográficas y clínico-metabólicas por sexo, noencontramos asociación en las primeras (p and gt;0.05), no obstante, antigüedad diagnostica y estadio clínico si se asocian con sexo, la primera de estas se asociósolo en hombres y la segunda en ambos sexos.Conclusiones La prevalencia de depresión es alta en las personas con diabetes ylas mujeres tienen mayor riesgo. La edad no muestra asociación entre personascon diabetes que están deprimidas, a diferencia de escolaridad, estado civil, y ocupación; la depresión se presentó más en personas con más antigüedad diagnóstica de diabetes y mayor IMC

Large-scale ocean connectivity and planktonic body size

Villarino, Ernesto ... et al.-- 13 pages, 5 figures, 5 tables, supplementary material https://dx.doi.org/10.1038/s41467-017-02535-8Global patterns of planktonic diversity are mainly determined by the dispersal of propagules with ocean currents. However, the role that abundance and body size play in determining spatial patterns of diversity remains unclear. Here we analyse spatial community structure - β-diversity - for several planktonic and nektonic organisms from prokaryotes to small mesopelagic fishes collected during the Malaspina 2010 Expedition. β-diversity was compared to surface ocean transit times derived from a global circulation model, revealing a significant negative relationship that is stronger than environmental differences. Estimated dispersal scales for different groups show a negative correlation with body size, where less abundant large-bodied communities have significantly shorter dispersal scales and larger species spatial turnover rates than more abundant small-bodied plankton. Our results confirm that the dispersal scale of planktonic and micro-nektonic organisms is determined by local abundance, which scales with body size, ultimately setting global spatial patterns of diversityThis research was funded by the project Malaspina 2010 Circumnavigation Expedition (Consolider-Ingenio 2010, CSD2008-00077) and cofounded by the Basque Government (Department Deputy of Agriculture, Fishing and Food Policy). [...] E.V. was supported by a PhD Scholarship granted by the Iñaki Goenaga−Technology Centres FoundationPeer Reviewe

Venezuelan Equine Encephalitis Virus, Southern Mexico

Evidence of enzootic and endemic Venezuelan equine encephalitis virus circulation in southern Mexico since the 1996 epizootic was obtained from serosurveys and virus isolations

Experimental study of differentially rotating supersonic plasma flows produced by aluminium wire array Z-pinches

A novel approach to cylindrical wire array z-pinches has been developed in order to create a rotating plasma flow analogous to astrophysical accretion discs. The method involves subjecting the wire array to a cusp magnetic field (B_r) to create converging off axis ablation streams to form a rotating flow. The rotation is sustained by the ram pressure of the ablation streams in a quasi-equilibrium state for approximately 150 ns. This corresponds to one full rotation of the plasma about the axis. The rotating plasma is supersonic with Mach number ~2 and a radially constant rotation velocity between 60 and 75 km/s; the angular velocity therefore has an r^-1 dependence and the flow is differential. A Thomson scattering diagnostic is used to measure the electron and ion temperatures as Te ~30 eV and Ti >55 eV and the ionisation of the plasma (Z) between 6 and 8. These parameters are used to calculate the Reynolds number (10^5 to 10^6) and magnetic Reynolds numbers (20 to 100) which are large enough for viscous and resistive effects to be negligible on the large scale of the flow. These are of sufficient magnitude for the experiment to be scalable to astrophysical accretion discs. Further more the Reynolds number for the experiment is large enough for shear instabilities to manifest in the plasma. Some evidence for this can be seen in XUV images and Thomson spectra which indicate the development of perturbations and vorticity within the flow. Predictions for the growth rate of the Kelvin Helmholtz instability, 12 to 40 ns, agree reasonably well with the observed perturbation growth of ~30 ns. It is also possible that shear instabilities are driving hydrodynamic turbulence. Turbulent heating of the plasma could explain the approximately 500 eV increase in the ion temperature observed from some Thomson spectra. Further work is required however to prove the existence of shear flows and turbulence within the experiments.Open Acces

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe