Journal of Mormon History Vol. 14, 1988

--The Popular History of Early Victorian Britain: A Mormon Contribution John F. C. Harrison, 3 --Heber J. Grant\u27s European Mission, 1903-1906 Ronald W. Walker, 17 --The Office of Presiding Patriarch: The Primacy Problem E. Gary Smith, 35 --In Praise of Babylon: Church Leadership at the 1851 Great Exhibition in London T. Edgar Lyon Jr., 49 --The Ecclesiastical Position of Women in Two Mormon Trajectories Ian G Barber, 63 --Franklin D. Richards and the British Mission Richard W. Sadler, 81 --Synoptic Minutes of a Quarterly Conference of the Twelve Apostles: The Clawson and Lund Diaries of July 9-11, 1901 Stan Larson, 9

Herald of Holiness Volume 64 Number 25 (1975)

01 Cover by Vern Scharer 02 The Power of Pentecost by General Superintendent Orville W. Jenkins 03 Quotation by Daniel Webster 04 The Power of the Printed Page by W.T. Purkiser 06 A Word-Centered Faith by David F. Nixon 07 A Lesson From a Wise Little Squirrel by Dorothy Coburn 08 What the Bible Teaches by Jerry W. McCant 09 Love and Duty by Nina Willis Walter 09 Lord, Give Me Something Real! by Gleason Hawn 10 The Cure for Anxiety by Alma Floyd 11 Bring Me the Books by Fred Parker 12 Good Words for thet Young by Glenn E. Sadler 14 Feeding on His Word by Morris A. Weigelt 15 Collector\u27s Item by Richard S. Barnett 16 Editorials by John A. Knight 18 A Couple of Good Books by Aarlie J. Hull 34 News of Religion 35 Answer Corner 38 By All Means: Would You Please Come? by Terry T. Maloneyhttps://digitalcommons.olivet.edu/cotn_hoh/2183/thumbnail.jp

Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design

The main task of the medicinal chemist is to design molecules that interact specifically with derailed or degenerating processes in a diseased organism, translating the available knowledge of pathobiochemical and physiological data into chemically useful information and structures. Current knowledge of the biological and chemical processes underlying diseases is vast and rapidly expanding. In particular the unraveling of the genome in combination with, for instance, the rapid development of structural biology has led to an explosion in available information and identification of new targets for chemotherapy. The task of translating this wealth of data into active and selective new drugs is an enormous, but realistic, challenge. It requires knowledge from many different fields, including molecular biology, chemistry, pharmacology, physiology, and medicine and as such requires a truly interdisciplinary approach. Ultimately, the goal is to design molecules that satisfy all the requirements for a candidate drug to function therapeutically. Therapeutic activity can then be achieved by an understanding of and control over structure and reactivity of the candidate drug through molecular manipulation

Designing organometallic compounds for catalysis and therapy

Bioorganometallic chemistry is a rapidly developing area of research. In recent years organometallic compounds have provided a rich platform for the design of effective catalysts, e.g. for olefin metathesis and transfer hydrogenation. Electronic and steric effects are used to control both the thermodynamics and kinetics of ligand substitution and redox reactions of metal ions, especially Ru II. Can similar features be incorporated into the design of targeted organometallic drugs? Such complexes offer potential for novel mechanisms of drug action through incorporation of outer-sphere recognition of targets and controlled activation features based on ligand substitution as well as metal- and ligand-based redox processes. We focus here on η 6-arene, η 5-cyclopentadienyl sandwich and half-sandwich complexes of Fe II, Ru II, Os II and Ir III with promising activity towards cancer, malaria, and other conditions. © 2012 The Royal Society of Chemistry

Observations and properties of candidate high frequency GPS radio sources in the AT20G survey

We used the Australia Telescope Compact Array (ATCA) to obtain 40 GHz and 95 GHz observations of a number of sources that were selected from the Australia Telescope Compact Array 20 GHz (AT20G) survey . The aim of the observations was to improve the spectral coverage for sources with spectral peaks near 20 GHz or inverted (rising) radio spectra between 8.6 GHz and 20 GHz. We present the radio observations of a sample of 21 such sources along with optical spectra taken from the ANU Siding Spring Observatory 2.3m telescope and the ESO-New Technology Telescope (NTT). We find that as a group the sources show the same level of variability as typical GPS sources, and that of the 21 candidate GPS sources roughly 60% appear to be genuinely young radio galaxies. Three of the 21 sources studied show evidence of being restarted radio galaxies. If these numbers are indicative of the larger population of AT20G radio sources then as many as 400 genuine GPS sources could be contained within the AT20G with up to 25% of them being restarted radio galaxies.Comment: 21 pages, 24 figures, Table 1 truncated at 11 column

The dust un-biased cosmic star formation history from the 20 cm VLA-COSMOS survey

We derive the cosmic star formation history (CSFH) out to z=1.3 using a sample of ~350 radio-selected star-forming galaxies, a far larger sample than in previous, similar studies. We attempt to differentiate between radio emission from AGN and star-forming galaxies, and determine an evolving 1.4 GHz luminosity function based on these VLA-COSMOS star forming galaxies. We precisely measure the high-luminosity end of the star forming galaxy luminosity function (SFR>100 M_Sol/yr; equivalent to ULIRGs) out to z=1.3, finding a somewhat slower evolution than previously derived from mid-infrared data. We find that more stars are forming in luminous starbursts at high redshift. We use extrapolations based on the local radio galaxy luminosity function; assuming pure luminosity evolution, we derive $L_* \propto (1+z)^{2.1 \pm 0.2}$ or $L_* \propto (1+z)^{2.5 \pm 0.1}$, depending on the choice of the local radio galaxy luminosity function. Thus, our radio-derived results independently confirm the ~1 order of magnitude decline in the CSFH since z~1.Comment: 9 pages, 7 figures; submitted to ApJ (revised following the referee report

What Powers the Compact Radio Emission in Nearby Elliptical and S0 Galaxies?

Many nearby early-type (elliptical and S0) galaxies contain weak (milli-Jansky level) nuclear radio sources on scales a few hundred parsecs or less. The origin of the radio emission, however, has remained unclear, especially in volume-limited samples that select intrinsically less luminous galaxies. Both active galactic nuclei and nuclear star formation have been suggested as possible mechanisms for producing the radio emission. This paper utilizes optical spectroscopic information to address this issue. A substantial fraction of the early-type galaxies surveyed with the Very Large Array by Wrobel & Heeschen (1991) exhibits detectable optical emission lines in their nuclei down to very sensitive limits. Comparison of the observed radio continuum power with that expected from the thermal gas traced by the optical emission lines implies that the bulk of the radio emission is nonthermal. Both the incidence and the strength of optical line emission correlate with the radio power. At a fixed line luminosity, ellipticals have stronger radio cores than S0s. The relation between radio power and line emission observed in this sample is consistent with the low-luminosity extension of similar relations seen in classical radio galaxies and luminous Seyfert nuclei. A plausible interpretation of this result is that the weak nuclear sources in nearby early-type galaxies are the low-luminosity counterparts of more powerful AGNs. The spectroscopic evidence supports this picture. Most of the emission-line objects are optically classified as Seyfert nuclei or low-ionization nuclear emission-line regions (LINERs), the majority of which are likely to be accretion-powered sources.Comment: LaTex, 16 pages including embedded figures. Accepted for publication in the Astrophysical Journa

Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005

The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management strategies using prospective, national surveillance of HUS and TTP, from 2003 to 2005 inclusive. We also investigated the links between these disorders and factors implicated in the aetiology of HUS and TTP including infections, chemotherapy, and immunosuppression. Most cases of HUS were caused by verocytotoxin-producing Escherichia coli (VTEC), of which serotype O157 predominated, although other serotypes were identified. The list of predisposing factors for TTP was more varied although use of immunosuppressive agents and severe sepsis, were the most frequent precipitants. The study demonstrates that while differentiating between HUS and TTP is sometimes difficult, in most cases the two syndromes have quite different predisposing factors and clinical parameters, enabling clinical and epidemiological profiling for these disorders