Phosphine-free chiral iridium catalysts for asymmetric catalytic hydrogenation of simple ketones

Novel pyridylalkylamine and aminopyridinato ligand stabilized iridium complexes with no P ligand are introduced. These complexes have been investigated as catalysts for asymmetric hydrogenation of simple ketones, resulting in an active catalyst for bulky alkyl aryl ketones that is α-methylpropiophenone. The ligands were synthesized from inexpensive starting materials and their modular design allows for the introduction of a broad variety of substitution patterns. Additionally, better activity and selectivity was observed at 20 °C and 20 bar H2 pressure with a catalyst loading as low as 0.05 mol% iridium. These phosphorus free catalysts have always been a central issue in both academic and industrial research

Multi-Method Research in Partnership with Myanmar Refugee Women in Dallas, Texas: Understanding How Ethnic Diversity Influences the Design and Development of a Resettlement Community Center

Founded in 2015, the Myanmar Women\u27s Research Project (MWRP) incorporates multiple participatory methods to help refugee women from Myanmar/Burma conceive of, conceptualize, develop, and sustain a community center devoted to resettlement. The project recognizes the multiple ethnicities and religious groups composing the Myanmar community and is committed to multi-ethnic participation of Myanmar women who form a community with considerable need for resettlement assistance. Indeed, refugees from Myanmar are some of the most vulnerable in the United States, and they face numerous challenges in accommodating American culture. The city of Dallas hosts one of the largest Myanmar communities in the United States, and its members contribute to a growing diverse and talented greater community of South Asians who are enriching the culture of Dallas. The project recognizes the arduous journey many Myanmar refugee women have experienced in their resettlement process, transiting through either Malaysia or Thailand to resettle finally in Dallas. Living in a local community called Vickery Meadow, Myanmar women are working with the presenter-researchers to develop a community center the capacities and activities of which can fulfill the multiple resettlement needs of the participants, and facilitate their involvement in American society through language acquisition, education, employment, child care, and youth development. The project has created several participatory structures including data collection processes sensitive to the cultural attachments of the participants, community forums in which participants can identify their priorities for resettlement, workshops incorporating artistic methods in which participants can create images of the support systems they want for themselves, and youth involvement in the research process. The presenter-researchers will share with conference participants how they worked closely with Myanmar women to use their community and cultural assets to conceive of and develop the community center prototype. And, they will highlight how key project interactions reflect a strong interpersonal dimension of human rights involving mutual respect for culture and ethnic identities, and the promotion of the dignity of involvement and control over actions designed to protect and advance the well-being of participants

Ir(III) complexes of diamine ligands for asymmetric ketone hydrogenation

The use of a combination of IrCl3 with a series of ligands derived from the C2-symmetric diamine diphenylethanediamine (DPEN) forms a catalyst capable of the asymmetric hydrogenation of ketones in up to 85% ee

Camchaya bolavenensis (Asteraceae: Vernonieae), a new species from Bolaven Plateau, southern Laos

A new species Camchaya bolavenensis (Asteraceae: Vernonieae: Centrapalinae) from Dong Hua Sao National Protected Area located in Bolaven Plateau, southern Laos, is described and illustrated. It resembles C. gracilis and C. thailandica in morphology but distinguished by its basally decumbent stem, margin of lamina with distinct (1–)2–3 teeth, 2–4 mm long on each side, invisible secondary veins, and a capitulum with 10–30 of florets

Utilization of a serum-free primary culture of cortical neurons by using cyclodextrins in neurobiological research

神経生物学的研究における基本的分析系の確立を目的として、シクロデキストリン（CD）を用いたラット大脳皮質神経細胞の初代培養を試みた。β-およびγ-CDは、無血清培地（ダルベッコ改変MEM/ハム培地）中で胎生16および18日目ラットの神経細胞を11日以上10％胎児ウシ血清を加えた培地中と同じ程度に生存させたが、α-CDには生存維持効果が無かった。β-CDはγ-CDより安定した生存維持効果を示したが、胎生21日目ラットの神経細胞を用いた場合は有意に生存率が低下し、新生児ラットでは生存維持効果が無かった。β-CDを用いた無血清培養では10％血清培地中と比べて神経突起の伸展が悪かったが、ときに顕著な突起伸展がみられ、これはCD分子に取り込まれた生理活性物質の作用と考えられた。また、β-CDを用いた無血清培養を利用してラット脳から精製したコンドロイチン硫酸プロテオグリカン（CSPG）の作用を検討し、CSPGがグルタミン酸による神経細胞死を防止すること、弱いながら培養神経細胞の生存を維持する作用をもつことを示した。以上の結果から、この無血清培養法は神経生物学的研究において有用な分析系となりうることを指摘した

trans-Dichlorido(2,2-dimethyl­propane-1,3-diamine)­bis­(triphenyl­phosphane)ruthenium(II)

In the title compound, [RuCl2(C5H14N2)(C18H15P)2], the RuII atom is six-coordinated, forming a slightly distorted octa­hedral geometry, with two chloride ions in an axial arrangement, and two P atoms of two triphenyl­phosphane and two chelating N atoms of the bidentate 2,2-dimethyl­propane-1,3-diamine ligand located in the equatorial plane. The average Ru—P, Ru—N and Ru—Cl bond lengths are 2.325 (18), 2.1845 (7) and 2.4123 (12) Å, respectively

ヒズミオモツタンソカンノゴウセイニオケルフアンテイタイノカガク

京都大学0048新制・論文博士工学博士乙第1066号論工博第172号新制||工||99A(附属図書館)1845UT51-44-A404(主査)教授 野崎 一, 教授 宍戸 圭一, 教授 小田 良平学位規則第5条第2項該当Kyoto UniversityDA

(R)-1,1′-Binaphthalene-2,2′-diol–(Z)-N-ethyl­ideneethanamine N-oxide (1/1)

In the title compound, C4H9NO·C20H14O2, the dihedral angle between the naphthalene ring systems of the binaphthalene­diol mol­ecule is 77.53 (14)°. In the crystal, the two components are linked by O—H⋯O hydrogen bonds, forming a zigzag chain along the c axis