12 research outputs found
Single Molecule Analysis Research Tool (SMART): An Integrated Approach for Analyzing Single Molecule Data
- Author
- A Borgia
- A Churbanov
- AT Brunger
- BP English
- C Joo
- DA Goodenough
- Daniel Herschlag
- Daniel J. Muller
- Dmitri S. Pavlichin
- E Boukobza
- E Neher
- E Neher
- E Rhoades
- EJ Bedrick
- F Qin
- G Baldini
- G Schwarz
- G Sherlock
- G Veldhuis
- GF Schroder
- H Nymeyer
- H Yang
- Hideo Mabuchi
- HP Lu
- I Csiszar
- J Park
- JA Hanson
- JF Beausang
- JG Saven
- JN Onuchic
- K Dolinski
- K Svoboda
- LA Liporace
- LE Baum
- M Andrec
- M Greenfeld
- M Gruebele
- MA Ditzler
- Max Greenfeld
- MD Stone
- MJ Wirth
- MP Elenko
- O Cappe
- P Giudici
- P Kienker
- PJ Choi
- PR Selvin
- R Roy
- S Jung
- S McGinnis
- S Weiss
- SA McKinney
- SH Chung
- SL Scott
- SV Solomatin
- SY Kim
- T Ha
- T Hastie
- T Hirschfeld
- T Ryden
- T Ryden
- TH Lee
- WE Moerner
- WJ Bruno
- WJ Greenleaf
- WP Ambrose
- WP Ambrose
- XW Zhuang
- XW Zhuang
- Z Xie
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
Single molecule studies have expanded rapidly over the past decade and have the ability to provide an unprecedented level of understanding of biological systems. A common challenge upon introduction of novel, data-rich approaches is the management, processing, and analysis of the complex data sets that are generated. We provide a standardized approach for analyzing these data in the freely available software package SMART: Single Molecule Analysis Research Tool. SMART provides a format for organizing and easily accessing single molecule data, a general hidden Markov modeling algorithm for fitting an array of possible models specified by the user, a standardized data structure and graphical user interfaces to streamline the analysis and visualization of data. This approach guides experimental design, facilitating acquisition of the maximal information from single molecule experiments. SMART also provides a standardized format to allow dissemination of single molecule data and transparency in the analysis of reported data
Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC
- Author
- Abi B
- Abud A Abed
- Acciarri R
- Acero MA
- Adames MR
- Adamov G
- Adamowski M
- Adams D
- Adinolfi M
- Aduszkiewicz A
- Aguilar J
- Ahmad Z
- Ahmed J
- Aimard B
- Ali-Mohammadzadeh B
- Alion T
- Allison K
- Alonso MJ Rodriguez
- AlRashed M
- Alt C
- Alton A
- Alvarez R
- Alzas P Barham
- Amedo P
- Anderson J
- Andreopoulos C
- Andreotti M
- Andrews M
- Andrianala F
- Andringa S
- Anfimov N
- Ankowski A
- Antoniassi M
- Antonova M
- Antoshkin A
- Antusch S
- Aranda-Fernandez A
- Arellano L
- Arnold LO
- Arroyave MA
- Asaadi J
- Asquith L
- Aurisano A
- Aushev V
- Autiero D
- Ayala Lara V
- Ayala-Torres M
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- Backhouse C
- Bagaturia I
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- Balasubramanian S
- Baldi P
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- Bambah B
- Barao F
- Barenboim G
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- Barranco Monarca J
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- Barrow JL
- Basharina-Freshville A
- Bashyal A
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- Batchelor C
- Battat JBR
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- Beigbeder C
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- Betancourt M
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- Verdugo A
- Vergani S
- Vermeulen MA
- Verzocchi M
- Vicenzi M
- Vignoli C
- Vilela C
- Viren B
- Vrba T
- Wachala T
- Waldron A
- Wallbank M
- Wallis C
- Wang H
- Wang J
- Wang L
- Wang MHLS
- Wang X
- Wang Y
- Wang Y
- Warburton K
- Warner D
- Wascko MO
- Waters D
- Watson A
- Wawrowska K
- Weatherly P
- Weber A
- Weber M
- Wei H
- Weinstein A
- Wenman D
- Wetstein M
- White A
- Whitehead LH
- Whittington D
- Wilking MJ
- Wilkinson A
- Wilkinson C
- Williams Z
- Wilson F
- Wilson RJ
- Wisniewski W
- Wolcott J
- Wongjirad T
- Wood A
- Wood K
- Worcester E
- Worcester M
- Wresilo K
- Wret C
- Wu W
- Wu W
- Xiao Y
- Xie F
- Yaeggy B
- Yandel E
- Yang G
- Yang K
- Yang T
- Yankelevich A
- Yershov N
- Yonehara K
- Yoon YS
- Young T
- Yu B
- Yu H
- Yu H
- Yu J
- Yu Y
- Yuan W
- Zaki R
- Zalesak J
- Zambelli L
- Zamorano B
- Zani A
- Zazueta L
- Zeller GP
- Zennamo J
- Zeug K
- Zhang C
- Zhang S
- Zhang Y
- Zhao M
- Zhivun E
- Zhu G
- Zimmerman ED
- Zucchelli S
- Zuklin J
- Zutshi V
- Zwaska R
- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 16/07/2022
- Field of study
DUNE is a dual-site experiment for long-baseline neutrino oscillation studies, neutrino astrophysics and nucleon decay searches. ProtoDUNE Dual Phase (DP) is a 6 × 6 × 6 m 3 liquid argon time-projection-chamber (LArTPC) that recorded cosmic-muon data at the CERN Neutrino Platform in 2019-2020 as a prototype of the DUNE Far Detector. Charged particles propagating through the LArTPC produce ionization and scintillation light. The scintillation light signal in these detectors can provide the trigger for non-beam events. In addition, it adds precise timing capabilities and improves the calorimetry measurements. In ProtoDUNE-DP, scintillation and electroluminescence light produced by cosmic muons in the LArTPC is collected by photomultiplier tubes placed up to 7 m away from the ionizing track. In this paper, the ProtoDUNE-DP photon detection system performance is evaluated with a particular focus on the different wavelength shifters, such as PEN and TPB, and the use of Xe-doped LAr, considering its future use in giant LArTPCs. The scintillation light production and propagation processes are analyzed and a comparison of simulation to data is performed, improving understanding of the liquid argon properties
The prolyl isomerase Pin1 in breast development and cancer
- Author
- A Albert
- A Ryo
- A Ryo
- AI Robles
- AJ Whitmarsh
- AS Duhaiman
- B Binetruy
- B Derijard
- BA Chabner
- BJ Druker
- C Albanese
- C Albanese
- C Gillett
- CL Arteaga
- CW Daniel
- D Hanahan
- D Harari
- D Patra
- DG Crenshaw
- DP Morris
- ER Andrechek
- F Fujimori
- G Fischer
- GM Wulf
- GM Wulf
- H Zheng
- I Bieche
- J Albanell
- J Bartkova
- J He
- J Roose
- J Russo
- JA Diehl
- JA Diehl
- JE Karp
- JF Rippmann
- JM Trimarchi
- JR Alt
- JR Nevins
- K Dolinski
- K Macleod
- KE Winkler
- KP Lu
- KP Lu
- KP Lu
- L Bakiri
- L Gerez
- L Hennig
- M Arevalo-Rodriguez
- M Jonsson
- M Karin
- M Shen
- M Sudol
- MB Yaffe
- MM Moasser
- N Muto
- O Kops
- OW Petersen
- P Blume-Jensen
- P Sicinski
- P Zacchi
- PE Shaw
- PJ Lu
- PJ Lu
- PJ Lu
- PJ van Diest
- PT Stukenberg
- PW Hinds
- PW Schlosshauer
- Q Yu
- R Munday
- R Nahta
- R Naidu
- R Ranganathan
- RA Weinberg
- RJ Lee
- S Ghosh
- SH Chao
- SK Muthuswamy
- SL Moulder
- SY Lin
- SY Zhang
- T Hsu
- T Hunter
- T Hunter
- T Sakakura
- T Smeal
- TC Wang
- TK MacLachlan
- V Fantl
- V Fantl
- W Liu
- X Wu
- XZ Zhou
- XZ Zhou
- YC Liou
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Design, construction and operation of the ProtoDUNE-SP Liquid Argon TPC
- Author
- Abi B
- Abud AA
- Acciarri R
- Acero MA
- Adames MR
- Adamov G
- Adams D
- Adinolfi M
- Aduszkiewicz A
- Aguilar J
- Ahmad Z
- Ahmed J
- Alba JLB
- Ali-Mohammadzadeh B
- Alion T
- Allison K
- Almeida RMD
- Alonso MJR
- Alrashed M
- Alt C
- Alton A
- Amedo P
- Anderson J
- Andreopoulos C
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- Andrews MP
- Andrianala F
- Andringa S
- Anfimov N
- Ankowski A
- Antoniassi M
- Antonova M
- Antoshkin A
- Antusch S
- Aranda-Fernandez A
- Ariga A
- Arnold LO
- Arroyave MA
- Asaadi J
- Asquith L
- Astiz ILDI
- Aurisano A
- Aushev V
- Autiero D
- Ayala-Torres M
- Azfar F
- B ACG
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- Back H
- Back JJ
- Backhouse C
- Baesso P
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- Balasubramanian S
- Baldi P
- Baller B
- Bambah B
- Barao F
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- Barker GJ
- Barkhouse W
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- Barrow JL
- Basharina-Freshville A
- Bashyal A
- Basque V
- Battat JBR
- Battisti F
- Bay F
- Bazetto MCQ
- Beacom JF
- Bechetoille E
- Behera B
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- Bellettini G
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- Beltramello O
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- Berger J
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- Bermeo LVG
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- Berns H
- Bertolucci S
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- Bezerra TJC
- Bhattacharjee M
- Bhuller S
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- Bueno LM
- Butorov I
- Cagnoli I
- Caicedo DAM
- Caiulo D
- Calabrese R
- Calafiura P
- Calcutt J
- Calin M
- Calvez S
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- Campanelli M
- Campo AOD
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- Christodoulou G
- Chukanov A
- Chung M
- Church E
- Cicero V
- Clarke P
- Coan TE
- Cocco AG
- Coelho JAB
- Collaboration DUNE
- Conley E
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- Conrad JM
- Convery M
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- Crespo-Anadon JI
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- Cussans D
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- Dalager O
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- Davies GS
- Davini S
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- Decowski MP
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- Dell'Acqua A
- DeMuth DM
- Dennis S
- Densham C
- Deptuch GW
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- Distefano C
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- Doering D
- Dolan S
- Dolek F
- Dolinski MJ
- Domine L
- Domizio SD
- Douglas D
- Douillet D
- Drake G
- Drielsma F
- Duarte L
- Duchesneau D
- Duffy K
- Dunne P
- Durkin T
- Duyang H
- Dvornikov O
- Dwyer DA
- Dyshkant AS
- Eads M
- Earle A
- Edmunds D
- Eisch J
- Emberger L
- Emery S
- Ereditato A
- Erjavec T
- Escobar CO
- Eurin G
- Evans JJ
- Ewart E
- Ezeribe AC
- Fahey K
- Fajardo LSG
- Falcone A
- Faní M
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- Farzan Y
- Fedoseev D
- Felix J
- Feng Y
- Fernandez-Martinez E
- Ferraro F
- Fields L
- Filip P
- Filthaut F
- Fiorentini A
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- Fitzpatrick RS
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- Fleming B
- Flight R
- Forero DV
- Fowler J
- Fox W
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- Franco D
- Freeman J
- Freestone J
- Fried J
- Friedland A
- Fuess S
- Furic I
- Furmanski AP
- Gabrielli A
- Gago A
- Gallagher H
- Gallas A
- Gallego-Ros A
- Gallice N
- Galymov V
- Gamberini E
- Gamble T
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- Gardiner S
- Gastler D
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- Giammaria P
- Giammaria T
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- Giri AK
- Giulio LD
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- Gonzalez-Cuevas JA
- Gonzalez-Lopez M
- Goodman MC
- Goodwin O
- Goswami S
- Gotti C
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- Gouvea AD
- Grace C
- Graham M
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- Granados E
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- Gratieri D
- Green P
- Greenler L
- Greer J
- Grenard J
- Griffith WC
- Groh M
- Grudzinski J
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- Guerzoni M
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- Guo B
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- Gutierrez R
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- Guzzo MM
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- Ha C
- Habig A
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- Laurenti G
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- Surdo A
- Susic V
- Suter L
- Sutera CM
- Svoboda R
- Szczerbinska B
- Szelc AM
- Tanaka HA
- Tapper A
- Tariq S
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- Tayloe R
- Teklu AM
- Tenti M
- Terao K
- Ternes CA
- Terranova F
- Terrazas IC
- Testera G
- Thakore T
- Thea A
- Thompson JL
- Thorn C
- Timm SC
- Tishchenko V
- Todd J
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- Tonazzo A
- Torbunov D
- Torti M
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- Vermeulen MA
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- Vicenzi M
- Vignoli C
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- Villanueva AC
- Viren B
- Vrba T
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- Waldron AV
- Wallbank M
- Wallis C
- Wang H
- Wang J
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- Wang MHLS
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- Warburton K
- Warner D
- Wascko MO
- Water RGVD
- Waters D
- Watson A
- Weatherly P
- Weber A
- Weber M
- Wei H
- Weinstein A
- Wenman D
- Wetstein M
- White A
- Whitehead LH
- Whittington D
- Wilking MJ
- Wilkinson C
- Williams Z
- Wilson F
- Wilson RJ
- Wisniewski W
- Wolcott J
- Wongjirad T
- Wood A
- Wood K
- Worcester E
- Worcester M
- Wret C
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- Wu W
- Xiao Y
- Xie F
- Yandel E
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- Yang T
- Yankelevich A
- Yershov N
- Yonehara K
- Young T
- Yu B
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- Yuan W
- Zaki R
- Zalesak J
- Zambelli L
- Zamorano B
- Zani A
- Zazueta L
- Zeller GP
- Zennamo J
- Zetina LMM
- Zeug K
- Zhang C
- Zhao M
- Zhivun E
- Zhu G
- Zilberman P
- Zimmerman ED
- Zito M
- Zucchelli S
- Zuklin J
- Zutshi V
- Zwaska R
- Publication venue
- 'IOP Publishing'
- Publication date
- 04/08/2021
- Field of study
The ProtoDUNE-SP detector is a single-phase liquid argon time projection chamber (LArTPC) that was constructed and operated in the CERN North Area at the end of the H4 beamline. This detector is a prototype for the first far detector module of the Deep Underground Neutrino Experiment (DUNE), which will be constructed at the Sandford Underground Research Facility (SURF) in Lead, South Dakota, U.S.A. The ProtoDUNE-SP detector incorporates full-size components as designed for DUNE and has an active volume of 7 × 6 × 7.2 m3. The H4 beam delivers incident particles with well-measured momenta and high-purity particle identification. ProtoDUNE-SP's successful operation between 2018 and 2020 demonstrates the effectiveness of the single-phase far detector design. This paper describes the design, construction, assembly and operation of the detector components
Searching for solar KDAR with DUNE
- Author
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- Chappell A
- Chardonnet E
- Charitonidis N
- Chatterjee A
- Chattopadhyay S
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- Chen Y
- Chen Z
- Cheon Y
- Cherdack D
- Chi C
- Childress S
- Chiriacescu A
- Chisnall G
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- Chong PS
- Choubey S
- Christensen A
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- Cocco AG
- Coelho JAB
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- Cremaldi L
- Cremonesi L
- Crespo-Anadón JI
- Crisler M
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- Cross R
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- da Motta H
- Dalager O
- David C
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- Davies GS
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- de Gouvêa A
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- De Lurgio P
- de Oliveira MAL
- De Roeck A
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- De Souza G
- de Souza HV
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- Debbins P
- Decowski MP
- Deisting A
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- DUNE Collaboration
- Dunne P
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- Dyshkant AS
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- Escobar CO
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- Galymov V
- Gamberini E
- Gamble T
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- Gandrajula R
- Gao F
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- Hamernik T
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- Harton J
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- Hasnip C
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- Hatfield KW
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- Heeger KM
- Heise J
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- Tapper A
- Tariq S
- Tatar E
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- Teklu AM
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- Terrazas IC
- Testera G
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- Thorn C
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- Tomassetti L
- Tonazzo A
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- Trevor J
- Trilov S
- Tripathi A
- Trzaska WH
- Tsai Y
- Tsai Y-T
- Tsamalaidze Z
- Tsang KV
- Tsverava N
- Tufanli S
- Tull C
- Tyley E
- Tzanov M
- Uboldi L
- Uchida MA
- Urheim J
- Usher T
- Uzunyan S
- Vagins MR
- Vahle P
- Valdiviesso GA
- Valencia E
- Valentim R
- Vallari Z
- Vallazza E
- Valle JWF
- Vallecorsa S
- Van Berg R
- Van de Water RG
- Varanini F
- Vargas D
- Varner G
- Vasel J
- Vasina S
- Vasseur G
- Vaughan N
- Vaziri K
- Vazquez WP
- Ventura S
- Verdugo A
- Vergani S
- Vermeulen MA
- Verzocchi M
- Vicenzi M
- Vignoli C
- Vilela C
- Villanueva AC
- Viren B
- Vrba T
- Wachala T
- Waldron AV
- Wallbank M
- Wallis C
- Wang H
- Wang J
- Wang L
- Wang MHLS
- Wang Y
- Wang Y
- Warburton K
- Warner D
- Wascko MO
- Waters D
- Watson A
- Weatherly P
- Weber A
- Weber M
- Wei H
- Weinstein A
- Wenman D
- Wetstein M
- White A
- Whitehead LH
- Whittington D
- Wilking MJ
- Wilkinson C
- Williams Z
- Wilson F
- Wilson RJ
- Wisniewski W
- Wolcott J
- Wongjirad T
- Wood A
- Wood K
- Worcester E
- Worcester M
- Wret C
- Wu W
- Wu W
- Xiao Y
- Xie F
- Yandel E
- Yang G
- Yang K
- Yang S
- Yang T
- Yankelevich A
- Yershov N
- Yonehara K
- Young T
- Yu B
- Yu H
- Yu H
- Yu J
- Yuan W
- Zaki R
- Zalesak J
- Zambelli L
- Zamorano B
- Zani A
- Zazueta L
- Zeller GP
- Zennamo J
- Zetina LMM
- Zeug K
- Zhang C
- Zhao M
- Zhivun E
- Zhu G
- Zilberman P
- Zimmerman ED
- Zito M
- Zucchelli S
- Zuklin J
- Zutshi V
- Zwaska R
- Publication venue
- Publication date
- Field of study
Low exposure long-baseline neutrino oscillation sensitivity of the DUNE experiment
- Author
- Abi B
- Abud AA
- Acciarri R
- Acero MA
- Adames MR
- Adamov G
- Adams D
- Adinolfi M
- Aduszkiewicz A
- Aguilar J
- Ahmad Z
- Ahmed J
- Aimard B
- Alba JLB
- Ali-Mohammadzadeh B
- Alion T
- Allison K
- Alonso MJR
- AlRashed M
- Alt C
- Alton A
- Amedo P
- Anderson J
- Andreopoulos C
- Andreotti M
- Andrews MP
- Andrianala F
- Andringa S
- Anfimov N
- Ankowski A
- Antoniassi M
- Antonova M
- Antoshkin A
- Antusch S
- Aranda-Fernandez A
- Arnold LO
- Arroyave MA
- Asaadi J
- Asquith L
- Astiz ILDI
- Aurisano A
- Aushev V
- Autiero D
- Ayala-Torres M
- Azfar F
- Back A
- Back H
- Back JJ
- Backhouse C
- Bagaturia I
- Bagby L
- Balashov N
- Balasubramanian S
- Baldi P
- Baller B
- Bambah B
- Barao F
- Barenboim G
- Barker GJ
- Barkhouse W
- Barnes C
- Barr G
- Barros A
- Barros N
- Barrow JL
- Basharina-Freshville A
- Bashyal A
- Basque V
- Battat JBR
- Battisti F
- Bay F
- Beacom JF
- Bechetoille E
- Behera B
- Belchior E
- Bellantoni L
- Bellettini G
- Bellini V
- Beltramello O
- Benekos N
- Berg RV
- Berger J
- Berkman S
- Bermeo LVG
- Bernardini P
- Berner RM
- Bertolucci S
- Betancourt M
- Bevan A
- Bezawada Y
- Bezerra TJC
- Bhardwaj A
- Bhatnagar V
- Bhattacharjee M
- Bhuller S
- Bhuyan B
- Biagi S
- Bian J
- Biassoni M
- Biery K
- Bilki B
- Bishai M
- Bitadze A
- Blake A
- Blaszczyk FDM
- Blazey GC
- Blucher E
- Boissevain J
- Bolognesi S
- Bolton T
- Bomben L
- Bonesini M
- Bongrand M
- Bonilla ER
- Bonilla-Diaz C
- Bonini F
- Bonis ID
- Booth A
- Boran F
- Bordoni S
- Borkum A
- Bostan N
- Bour P
- Bourgeois C
- Boyden D
- Bracinik J
- Braga D
- Brailsford D
- Branca A
- Brandt A
- Bremer J
- Brew C
- Brice SJ
- Brizzolari C
- Bromberg C
- Brooke J
- Bross A
- Brunetti G
- Brunetti M
- Buchanan N
- Budd H
- Bueno LM
- Butorov I
- Cagnoli I
- Caicedo DAM
- Caiulo D
- Calabrese R
- Calafiura P
- Calcutt J
- Calin M
- Calvez S
- Calvo E
- Caminata A
- Campanelli M
- Caratelli D
- Carini G
- Carlus B
- Carneiro MF
- Carniti P
- Carranza H
- Carroll T
- Castillo A
- Castromonte C
- Catano-Mur E
- Cattadori C
- Cavalier F
- Cavanna F
- Centro S
- Cerati G
- Cervelli A
- Chalifour M
- Chappell A
- Chardonnet E
- Charitonidis N
- Chatterjee A
- Chattopadhyay S
- Chen H
- Chen M
- Chen Y
- Chen Z
- Cheon Y
- Cherdack D
- Chi C
- Childress S
- Chiriacescu A
- Chisnall G
- Cho K
- Choate S
- Chokheli D
- Chong PS
- Christensen A
- Christian D
- Christodoulou G
- Chukanov A
- Chung M
- Church E
- Cicero V
- Clarke P
- Coan TE
- Cocco AG
- Coelho JAB
- Collaboration DUNE
- Colton N
- Conley E
- Conley R
- Conrad JM
- Convery M
- Copello S
- Cremaldi L
- Cremonesi L
- Crespo-Anadón JI
- Crisler M
- Cristaldo E
- Cross R
- Cudd A
- Cuesta C
- Cui Y
- Cussans D
- Dalager O
- David C
- David Q
- Davies GS
- Davini S
- Dawson J
- De K
- Debbins P
- Decowski MP
- Deisting A
- Delbart A
- Delepine D
- Delgado M
- Delgado MAR
- Dell'Acqua A
- DeMuth DM
- Dennis S
- Densham C
- Deptuch GW
- Devi R
- Dharmapalan R
- Dias M
- Diaz F
- Ding P
- Distefano C
- Diurba R
- Diwan M
- Djurcic Z
- Doering D
- Dolan S
- Dolek F
- Dolinski MJ
- Domine L
- Domizio SD
- Douglas D
- Douillet D
- Drake G
- Drielsma F
- Duarte L
- Duchesneau D
- Duffy K
- Dunne P
- Duyang H
- Dvornikov O
- Dwyer DA
- Dyshkant AS
- Díaz JS
- Eads M
- Earle A
- Edmunds D
- Eisch J
- Emberger L
- Emery S
- Ereditato A
- Erjavec T
- Escobar CO
- Eurin G
- Evans JJ
- Ewart E
- Ezeribe AC
- Fahey K
- Fajardo LSG
- Falcone A
- Fani' M
- Farnese C
- Farzan Y
- Fedoseev D
- Felix J
- Feng Y
- Fernandez-Martinez E
- Ferraro F
- Fields L
- Filip P
- Filthaut F
- Fiorentini A
- Fiorini M
- Fitzpatrick RS
- Flanagan W
- Fleming B
- Flight R
- Fogarty S
- Foreman W
- Forero DV
- Forero JFC
- Fowler J
- Fox W
- Franc J
- Francis K
- Franco D
- Freeman J
- Freestone J
- Fried J
- Friedland A
- Fuess S
- Furic IK
- Furmanski AP
- Gabrielli A
- Gago A
- Gallagher H
- Gallas A
- Gallego-Ros A
- Gallice N
- Galymov V
- Gamberini E
- Gamble T
- Ganacim F
- Gandhi R
- Gandrajula R
- Gao F
- Gao S
- Garcia-Gamez D
- García-Peris MÁ
- Gardiner S
- Gastler D
- Gauvreau J
- Ge G
- Geffroy N
- Gelli B
- Gendotti A
- Gent S
- Ghorbani-Moghaddam Z
- Giammaria P
- Giammaria T
- Gibin D
- Gil-Botella I
- Gilligan S
- Girerd C
- Giri AK
- Giulio LD
- Gnani D
- Gogota O
- Gold M
- Gollapinni S
- Gollwitzer K
- Gomes RA
- Gonnella F
- Gonzalez-Cuevas JA
- Gonzalez-Diaz D
- Gonzalez-Lopez M
- Goodman MC
- Goodwin O
- Goswami S
- Gotti C
- Goudzovski E
- Gouvêa AD
- Grace C
- Gran R
- Granados E
- Granger P
- Grant A
- Grant C
- Gratieri D
- Green P
- Greenler L
- Greer J
- Grenard J
- Griffith WC
- Groh M
- Grudzinski J
- Grzelak K
- Gu W
- Guardincerri E
- Guarino V
- Guarise M
- Guenette R
- Guerard E
- Guerzoni M
- Guffanti D
- Guglielmi A
- Guo B
- Gupta V
- Guthikonda KK
- Gutierrez R
- Guzowski P
- Guzzo MM
- Gwon S
- Ha C
- Habig A
- Hadavand H
- Haenni R
- Hahn A
- Haiston J
- Hamacher-Baumann P
- Hamernik T
- Hamilton P
- Han J
- Harris DA
- Hartnell J
- Hartnett T
- Harton J
- Hasegawa T
- Hasnip C
- Hatcher R
- Hatfield KW
- Hatzikoutelis A
- Hayes C
- Hayrapetyan K
- Hays J
- Hazen E
- He M
- Heavey A
- Heeger KM
- Heise J
- Henry S
- Herner K
- Hewes J
- Hill T
- Hillier SJ
- Himmel A
- Hinkle E
- Hirsch LR
- Ho J
- Hoff J
- Holanda PCD
- Holin A
- Hoppe E
- Horton-Smith GA
- Hostert M
- Hourlier A
- Howard B
- Howell R
- Hristova I
- Hronek MS
- Huang J
- Iles G
- Ilic N
- Iliescu AM
- Illingworth R
- Ingratta G
- Ioannisian A
- Irwin B
- Isenhower L
- Itay R
- Jackson CM
- Jain V
- James E
- Jang W
- Jargowsky B
- Jediny F
- Jena D
- Jeong YS
- Jesús-Valls C
- Ji X
- Jiang L
- Jiménez S
- Jipa A
- Johnson R
- Johnston N
- Jones B
- Jones SB
- Jong PD
- Judah M
- Jung CK
- Junk T
- Jwa Y
- Kabirnezhad M
- Kaboth A
- Kadenko I
- Kaira D
- Kakorin I
- Kalitkina A
- Kamiya F
- Kaneshige N
- Karagiorgi G
- Karaman G
- Karcher A
- Karolak M
- Karyotakis Y
- Kasai S
- Kasetti SP
- Kashur L
- Kazaryan N
- Kearns E
- Keener P
- Kelly KJ
- Kemp E
- Kemularia O
- Ketchum W
- Kettell SH
- Khabibullin M
- Khotjantsev A
- Khvedelidze A
- Kim D
- King B
- Kirby B
- Kirby M
- Klein J
- Koehler K
- Koerner LW
- Koh DH
- Kohn S
- Koller PP
- Kolupaeva L
- Korablev D
- Kordosky M
- Kosc T
- Kose U
- Kostelecký VA
- Kothekar K
- Kreczko L
- Krennrich F
- Kreslo I
- Kropp W
- Kudenko Y
- Kudryavtsev VA
- Kulagin S
- Kumar J
- Kumar P
- Kumar R
- Kunze P
- Kurita N
- Kuruppu C
- Kus V
- Kutter T
- Kvasnicka J
- Kwak D
- Lambert A
- Land BJ
- Lane CE
- Lang K
- Langford T
- Langstaff M
- Larkin J
- Lasorak P
- Last D
- Lastoria C
- Laundrie A
- Laurenti G
- Lawrence A
- Lazanu I
- LaZur R
- Lazzaroni M
- Le T
- Leardini S
- Learned J
- LeBrun P
- LeCompte T
- Lee C
- Lee SY
- Lehnert R
- Leitner M
- Lepin LM
- Li SW
- Li T
- Li Y
- Liao H
- Lin CS
- Lin Q
- Lin S
- Lineros RA
- Ling J
- Lisbôa AFS
- Lister A
- Littlejohn BR
- Liu J
- Lockwitz S
- Loew T
- Lokajicek M
- Lomidze I
- Long K
- Lord T
- LoSecco JM
- Louis WC
- Lu X-G
- Luk KB
- Lunday B
- Luo X
- Luppi E
- Lurgio PD
- Lux T
- Luzio VP
- MacFarlane D
- Machado AA
- Machado P
- Macias CT
- Macier JR
- Maddalena A
- Madera A
- Madigan P
- Magill S
- Mahn K
- Maio A
- Major A
- Maloney JA
- Mandrioli G
- Mandujano RC
- Maneira J
- Manenti L
- Manly S
- Mann A
- Manolopoulos K
- Manyam VN
- Manzanillas L
- Marchan M
- Marchionni A
- Marciano W
- Marfatia D
- Mariani C
- Maricic J
- Marie R
- Marinho F
- Marino AD
- Marsden D
- Marshak M
- Marshall CM
- Marshall J
- Marteau J
- Martin-Albo J
- Martinez N
- Martynenko S
- Mascagna V
- Mason K
- Mastbaum A
- Matichard F
- Matsuno S
- Matthews J
- Mauger C
- Mauri N
- Mavrokoridis K
- Mawby I
- Mazza R
- Mazzacane A
- Mazzucato E
- McAskill T
- McCluskey E
- McConkey N
- McFarland KS
- McGrew C
- McNab A
- Mefodiev A
- Mehta P
- Melas P
- Mena O
- Mendez H
- Mendez P
- Menegolli A
- Menendez PF
- Meng G
- Messier MD
- Metcalf W
- Mettler T
- Mewes M
- Meyer H
- Miao T
- Michna G
- Miedema T
- Mikola V
- Milincic R
- Miller G
- Miller W
- Mills J
- Milne C
- Mineev O
- Minotti A
- Miotto GL
- Miranda OG
- Miravé PM
- Miryala S
- Mishra CS
- Mishra SR
- Mislivec A
- Mladenov D
- Mocioiu I
- Moffat K
- Moggi N
- Mohanta R
- Mohayai TA
- Mokhov N
- Molina J
- Monarca JB
- Monsalve SA
- Montagna E
- Montanari A
- Montanari C
- Montanari D
- Montiel CB
- Moon J
- Moon SH
- Mooney M
- Moor AF
- Morales MF
- Moreno D
- Morquecho MAH
- Morris C
- Mossey C
- Motta HD
- Motuk E
- Moura CA
- Mousseau J
- Mouster G
- Mu W
- Mualem L
- Mueller J
- Muether M
- Mufson S
- Muheim F
- Muir A
- Mulhearn M
- Munford D
- Muramatsu H
- Murphy S
- Musser J
- Méndez DP
- Nachtman J
- Nagu S
- Nalbandyan M
- Nandakumar R
- Naples D
- Narita S
- Nath A
- Navrer-Agasson A
- Nayak N
- Nebot-Guinot M
- Negishi K
- Nelson JK
- Nesbit J
- Nessi M
- Neto JRTDM
- Neves FB
- Newbold D
- Newcomer M
- Newhart D
- Newton H
- Nichol R
- Nicolas-Arnaldos F
- Niner E
- Nishimura K
- Norman A
- Norrick A
- Northrop R
- Noto LD
- Novella P
- Nowak JA
- Nunes MS
- Oberling M
- Ochoa-Ricoux JP
- Oliveira MALD
- Olivier A
- Olshevskiy A
- Onel Y
- Onishchuk Y
- Oregui BT
- Ott J
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- Pakvasa S
- Palacio G
- Palamara O
- Palestini S
- Paley JM
- Pallavicini M
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- Palomino-Gallo JL
- Pantic E
- Paolone V
- Papadimitriou V
- Papaleo R
- Papanestis A
- Paramesvaran S
- Parke S
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- Pasternak J
- Pater J
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- Patterson RB
- Patton SJ
- Patzak T
- Paudel A
- Paulos B
- Paulucci L
- Pavlovic Z
- Pawloski G
- Payne D
- Pec V
- Peeters SJM
- Pennacchio E
- Penzo A
- Peres LDS
- Peres OLG
- Perry J
- Pershey D
- Pessina G
- Petrillo G
- Petta C
- Petti R
- Pia V
- Piastra F
- Pickering L
- Pietropaolo F
- Plata MM
- Plunkett R
- Poling R
- Pons X
- Poonthottathil N
- Poppi F
- Pordes S
- Porter J
- Potekhin M
- Potenza R
- Potukuchi BVKS
- Pozimski J
- Pozzato M
- Prakash S
- Prakash T
- Prest M
- Prince S
- Psihas F
- Pugnere D
- Qian X
- Raaf JL
- Radeka V
- Rademacker J
- Radics B
- Rafique A
- Raguzin E
- Rai M
- Rajaoalisoa M
- Rakhno I
- Rakotonandrasana A
- Rakotondravohitra L
- Ramachers YA
- Rameika R
- Ramson B
- Rappoldi A
- Raselli G
- Ratoff P
- Raut S
- Razakamiandra RF
- Rea E
- Real JS
- Rebel B
- Reggiani-Guzzo M
- Rehak T
- Reichenbacher J
- Reitzner SD
- Renshaw A
- Rescia S
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- Reynolds A
- Ribas M
- Riboldi S
- Riccio C
- Riccobene G
- Rice LCJ
- Ricol J
- Rigamonti A
- Rigaut Y
- Rivera D
- Robayo FF
- Robert A
- Rochester L
- Roda M
- Rodrigues P
- Rodríguez AB
- Roeck AD
- Romeri VD
- Rondon JR
- Rosauro-Alcaraz S
- Rosenberg M
- Rosier P
- Roskovec B
- Rossella M
- Rossi M
- Rout J
- Roy P
- Rubbia A
- Rubbia C
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- Rybnikov A
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- Sandberg V
- Sanders DA
- Sankey D
- Santana S
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- Saoulidou N
- Sapienza P
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- Sarcevic I
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- Savinov V
- Scaramelli A
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- Schellman H
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- Schukraft A
- Segreto E
- Selyunin A
- Senise CR
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- Sergi A
- Sfar HR
- Sgalaberna D
- Shaevitz MH
- Shafaq S
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- Sharankova R
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- Sheshukov A
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- Shoemaker I
- Shooltz D
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- Sitraka A
- Siyeon K
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- Smith P
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- Tanaka HA
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- Trevor J
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- Trzaska WH
- Tsai Y
- Tsai Y-T
- Tsamalaidze Z
- Tsang KV
- Tsverava N
- Tufanli S
- Tull C
- Tyley E
- Tzanov M
- Uboldi L
- Uchida MA
- Urheim J
- Usher T
- Uzunyan S
- Vagins MR
- Vahle P
- Valdiviesso GA
- Valentim R
- Vallari Z
- Vallazza E
- Valle JWF
- Vallecorsa S
- Varanini F
- Vargas D
- Varner G
- Vasel J
- Vasina S
- Vasseur G
- Vaughan N
- Vaziri K
- Vazquez WP
- Ventura S
- Verdugo A
- Vergani S
- Vermeulen MA
- Verzocchi M
- Vicenzi M
- Vignoli C
- Vilela C
- Villanueva AC
- Viren B
- Vrba T
- Wachala T
- Waldron AV
- Wallbank M
- Wallis C
- Wang H
- Wang J
- Wang L
- Wang MHLS
- Wang Y
- Wang Y
- Warburton K
- Warner D
- Wascko MO
- Water RGVD
- Waters D
- Watson A
- Weatherly P
- Weber A
- Weber M
- Wei H
- Weinstein A
- Wenman D
- Wetstein M
- White A
- Whitehead LH
- Whittington D
- Wilking MJ
- Wilkinson C
- Williams Z
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- Wilson RJ
- Wisniewski W
- Wolcott J
- Wongjirad T
- Wood A
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- Xiao Y
- Xie F
- Yandel E
- Yang G
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- Yang T
- Yankelevich A
- Yershov N
- Yonehara K
- Young T
- Yu B
- Yu H
- Yu H
- Yu J
- Yuan W
- Zaki R
- Zalesak J
- Zambelli L
- Zamorano B
- Zani A
- Zazueta L
- Zeller GP
- Zennamo J
- Zetina LMM
- Zeug K
- Zhang C
- Zhao M
- Zhivun E
- Zhu G
- Zimmerman ED
- Zucchelli S
- Zuklin J
- Zutshi V
- Zwaska R
- Publication venue
- Publication date
- Field of study
The Deep Underground Neutrino Experiment (DUNE) will produce world-leading neutrino oscillation measurements over the lifetime of the experiment. In this work, we explore DUNE's sensitivity to observe charge-parity violation (CPV) in the neutrino sector, and to resolve the mass ordering, for exposures of up to 100 kiloton-megawatt-years (kt-MW-yr). The analysis includes detailed uncertainties on the flux prediction, the neutrino interaction model, and detector effects. We demonstrate that DUNE will be able to unambiguously resolve the neutrino mass ordering at a 3σ (5σ) level, with a 66 (100) kt-MW-yr far detector exposure, and has the ability to make strong statements at significantly shorter exposures depending on the true value of other oscillation parameters. We also show that DUNE has the potential to make a robust measurement of CPV at a 3σ level with a 100 kt-MW-yr exposure for the maximally CP-violating values \delta_{\rm CP}} = \pm\pi/2. Additionally, the dependence of DUNE's sensitivity on the exposure taken in neutrino-enhanced and antineutrino-enhanced running is discussed. An equal fraction of exposure taken in each beam mode is found to be close to optimal when considered over the entire space of interest
Negative pressure pulmonary edema: endobronchial intubation or acute lung injury in a predisposed patient?
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Negative Pressure Pulmonary Edema Following Foramen Magnum Decompression for Chiari Malformation Type I -Case Report-
- Author
- Broccard AF Liaudet L, Aubert JD,
- Cascade PN Alexander GD, Mackie DS
- Corbett JJ Butler AB, Kaufman B
- Dolinski SY MacGregor DA, Scuderi
- Itoh Y Kuwahara N, Hirano Y, Sasaj
- Lang SA Duncan PG, Shephard DAE, H
- Mortero RF Orahovac Z, Tsueda K, B
- Samet A Fossard JP, Samet H, Hirch
- Westreich R Sampson I, Shaari CM,
- Publication venue
- 'Japan Neurosurgical Society'
- Publication date
- 01/01/2008
- Field of study
Model organism data evolving in support of translational medicine
- Author
- A Bradley
- A Cortelazzo
- A Ganner
- A Goffeau
- A Krogh
- A Ordas
- A Seth
- AC Dar
- AC Ericsson
- AC Spradling
- AD Attie
- AE Cast
- AG Alexander
- AH Kachroo
- AH Kachroo
- AM Deshpande
- AM Taylor
- AP Deveau
- B Hunyadi
- BP Kennedy
- Brian R. Calvi
- C Chakraborty
- C Kless
- C Parng
- C Pauli
- Carol J. Bult
- CC Lindegren
- CC Lindegren.
- CC Teixeira
- CH Williams
- CL Smith
- Collaborative Cross Consortium.
- CW Feng
- CX Pan
- CY Chu
- Cynthia Smith
- D Bilder
- D Botstein
- D Clair St
- D Libkind
- D Oliveira
- D Smedley
- DGDG Howe
- DJ Rigden
- DK Kim
- DM Krupke
- Douglas G. Howe
- E Bier
- E Culetto
- E Garralda
- EA Winzeler
- EF Griffin
- EF Remmers
- EJ Chesler
- EJ Chesler
- EJ Louis
- EM Bank
- ES Noël
- F Germani
- G Duck
- G Gaudenzi
- G Giaever
- G Montalbano
- G Voer de
- GA Churchill
- GD Evrony
- Gene Ontology Consortium.
- GH Millburn
- GJ Lieschke
- GM Rubin
- GTEx Consortium.
- H Gao
- H Jacob
- H Laale
- H Wang
- HJ Bellen
- HJ Drabkin
- HJ Jacob
- HJ Jacob
- HT Chao
- IA Pena
- International Mouse Knockout Consortium.
- J Apfeld
- J Berger
- J Lin
- J Rine
- J Sprague
- J Wang
- JA Williams
- James A. Kadin
- JB Phillips
- JH Finger
- JJ Reynolds
- JK Skelton
- JL Bandura
- JM Kim
- Joel E. Richardson
- JP Lasserre
- JP Leite
- JP Rapp
- JQ Wu
- Judith A. Blake
- JW Wenger
- JX Chong
- K Dolinski
- KH Morelli
- KL Howe
- KL Svenson
- L Ma
- LA Shepel
- LD Shultz
- LE Dobrolecki
- LJ Sittig
- LS Gramates
- M Bjursell
- M Bond
- M Costanzo
- M Costanzo
- M Gunawan
- M Hidalgo
- M Kitada
- M MacPhee
- M Novo
- M Renna
- M Riessland
- M Vidal
- M Wang
- M Wilke
- MA Cenci
- MB Thompson
- MC Cervantes
- MC Fishman
- MD Wilkinson
- ME Díaz-Casado
- MF Wangler
- MF Wangler
- MJ Williams
- MS Skrzypek
- MW Metzger
- MY Chou
- N Perrimon
- ND Quach
- NS Yarla
- O Kanca
- OnhaplophaseanddiplophaseofsomeSacch Winge
- P Hieter
- P Mali
- PE Dickson
- R Combe
- Ranjana Kishore
- RJ Duronio
- RJ Planta
- RM White
- RT Molenhuis
- RW Logan
- S Baxendale
- S Carbon
- S Ghaemmaghami
- S Hara
- S Hindle
- S Köhler
- S Köhler
- S Köhler
- S Lesly
- S Poux
- SA Sansone
- SDM Brown
- SG Oliver
- Sierra A. T. Moxon
- SR Engel
- Stacia R. Engel
- Stanley J. F. Laulederkind
- Suzanna E. Lewis
- SY Wu
- T Aitman
- T Gabaldón
- T Hirsch
- T Oka
- T Pietri
- T Tsuji
- TA Manolio
- TC Kaufman
- Thomas C. Kaufman
- TM Keane
- TM Lowe
- TM Lowe
- TW Robbins
- V Picher-Martel
- VC Jordan
- VM Philip
- WF Dietrich
- WH Wu
- WK Huh
- WM Gelbart
- WP Bone
- Y Hu
- Y Hu
- Y Song
- YM Bradford
- Yvonne M. Bradford
- Publication venue
- Nature Publishing Group
- Publication date
- 17/09/2018
- Field of study
Model organism databases (MODs) have been collecting and integrating biomedical research data for 30 years and were designed to meet specific needs of each model organism research community. The contributions of model organism research to understanding biological systems would be hard to overstate. Modern molecular biology methods and cost reductions in nucleotide sequencing have opened avenues for direct application of model organism research to elucidating mechanisms of human diseases. Thus, the mandate for model organism research and databases has now grown to include facilitating use of these data in translational applications. Challenges in meeting this opportunity include the distribution of research data across many databases and websites, a lack of data format standards for some data types, and sustainability of scale and cost for genomic database resources like MODs. The issues of widely distributed data and application of data standards are some of the challenges addressed by FAIR (Findable, Accessible, Interoperable, and Re-usable) data principles. The Alliance of Genome Resources is now moving to address these challenges by bringing together expertly curated research data from fly, mouse, rat, worm, yeast, zebrafish, and the Gene Ontology consortium. Centralized multi-species data access, integration, and format standardization will lower the data utilization barrier in comparative genomics and translational applications and will provide a framework in which sustainable scale and cost can be addressed. This article presents a brief historical perspective on how the Alliance model organisms are complementary and how they have already contributed to understanding the etiology of human diseases. In addition, we discuss four challenges for using data from MODs in translational applications and how the Alliance is working to address them, in part by applying FAIR data principles. Ultimately, combined data from these animal models are more powerful than the sum of the parts
Model organism data evolving in support of translational medicine
- Author
- A Bradley
- A Cortelazzo
- A Ganner
- A Goffeau
- A Krogh
- A Ordas
- A Seth
- AC Dar
- AC Ericsson
- AC Spradling
- AD Attie
- AE Cast
- AG Alexander
- AH Kachroo
- AH Kachroo
- AM Deshpande
- AM Taylor
- AP Deveau
- B Hunyadi
- BP Kennedy
- Brian R. Calvi
- C Chakraborty
- C Kless
- C Parng
- C Pauli
- Carol J. Bult
- CC Lindegren
- CC Lindegren.
- CC Teixeira
- CH Williams
- CL Smith
- Collaborative Cross Consortium.
- CW Feng
- CX Pan
- CY Chu
- Cynthia Smith
- D Bilder
- D Botstein
- D Clair St
- D Libkind
- D Oliveira
- D Smedley
- DGDG Howe
- DJ Rigden
- DK Kim
- DM Krupke
- Douglas G. Howe
- E Bier
- E Culetto
- E Garralda
- EA Winzeler
- EF Griffin
- EF Remmers
- EJ Chesler
- EJ Chesler
- EJ Louis
- EM Bank
- ES Noël
- F Germani
- G Duck
- G Gaudenzi
- G Giaever
- G Montalbano
- G Voer de
- GA Churchill
- GD Evrony
- Gene Ontology Consortium.
- GH Millburn
- GJ Lieschke
- GM Rubin
- GTEx Consortium.
- H Gao
- H Jacob
- H Laale
- H Wang
- HJ Bellen
- HJ Drabkin
- HJ Jacob
- HJ Jacob
- HT Chao
- IA Pena
- International Mouse Knockout Consortium.
- J Apfeld
- J Berger
- J Lin
- J Rine
- J Sprague
- J Wang
- JA Williams
- James A. Kadin
- JB Phillips
- JH Finger
- JJ Reynolds
- JK Skelton
- JL Bandura
- JM Kim
- Joel E. Richardson
- JP Lasserre
- JP Leite
- JP Rapp
- JQ Wu
- Judith A. Blake
- JW Wenger
- JX Chong
- K Dolinski
- KH Morelli
- KL Howe
- KL Svenson
- L Ma
- LA Shepel
- LD Shultz
- LE Dobrolecki
- LJ Sittig
- LS Gramates
- M Bjursell
- M Bond
- M Costanzo
- M Costanzo
- M Gunawan
- M Hidalgo
- M Kitada
- M MacPhee
- M Novo
- M Renna
- M Riessland
- M Vidal
- M Wang
- M Wilke
- MA Cenci
- MB Thompson
- MC Cervantes
- MC Fishman
- MD Wilkinson
- ME Díaz-Casado
- MF Wangler
- MF Wangler
- MJ Williams
- MS Skrzypek
- MW Metzger
- MY Chou
- N Perrimon
- ND Quach
- NS Yarla
- O Kanca
- OnhaplophaseanddiplophaseofsomeSacch Winge
- P Hieter
- P Mali
- PE Dickson
- R Combe
- Ranjana Kishore
- RJ Duronio
- RJ Planta
- RM White
- RT Molenhuis
- RW Logan
- S Baxendale
- S Carbon
- S Ghaemmaghami
- S Hara
- S Hindle
- S Köhler
- S Köhler
- S Köhler
- S Lesly
- S Poux
- SA Sansone
- SDM Brown
- SG Oliver
- Sierra A. T. Moxon
- SR Engel
- Stacia R. Engel
- Stanley J. F. Laulederkind
- Suzanna E. Lewis
- SY Wu
- T Aitman
- T Gabaldón
- T Hirsch
- T Oka
- T Pietri
- T Tsuji
- TA Manolio
- TC Kaufman
- Thomas C. Kaufman
- TM Keane
- TM Lowe
- TM Lowe
- TW Robbins
- V Picher-Martel
- VC Jordan
- VM Philip
- WF Dietrich
- WH Wu
- WK Huh
- WM Gelbart
- WP Bone
- Y Hu
- Y Hu
- Y Song
- YM Bradford
- Yvonne M. Bradford
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study