151 research outputs found
Process evaluation of electron beam irradiation-based biodegradation relevant to lignocellulose bioconversion
Intermediate-depth icequakes and harmonic tremor in an Alpine glacier (glacier d 'Argentiere,France): evidence for hydraulic fracturing
International audienceWe detected several thousand deep englacial icequakes on Glacier d’Argentiere (Mont-Blanc Massif) between 30 March and 3 May 2012. These events have been classified in eight clusters. Inside each cluster, the waveforms are similar for P-waves and S-waves, although the time delay between the P-waves and S-waves vary by up to 0.03 s, indicating an extended source area. Although these events were recorded by a single accelerometer, they were roughly located using a polarization analysis. The deepest events were located at a depth of 130 m, 60 m above the ice/bed interface. The clusters are separated in space. The largest cluster extends over about 100 m. For this cluster, the strike of the rupture plane is nearly parallel to the direction of the open crevasses, and the dip angle is 56◦. Deep icequakes occur in bursts of activity that last for a few hours and are separated by quiet periods. Many events occurred on 28-29 April 2012, during the warmest days, when snow melting was likely important. The distribution of events in time and space obeys a power law, as also observed for earthquakes, but with larger exponents.The polarity of the P-waves for all of the events is consistent with tensile faulting. Finally, between 25 April and 3 May, we observed a gliding harmonic tremor with a fun- damental resonance frequency that varied between 30 Hz and 38 Hz, with additional higher frequency harmonics. During this time we also observed shallow hybrid events with high-frequency onsets and a monochromatic coda. These events might be produced by the propagation of fractures and the subsequent flow of water into the fracture. The strongest resonance was observed just after a strong burst of deep icequakes, and during an un- usually warm period when the snow height decreased by 60 cm in one week. The res- onance frequency shows a succession of several sharp decreases and phases of progressive increases. One of the strongest negative steps of the resonance frequency on 28 April coincides with a burst of deep icequakes. These events appear to be associated with the propagation of fractures, which can explain the decrease in the resonance frequency. Finally, we observed an acceleration of glacier flow on 29 April and suggested that melt-water had reached the ice/bed interface. These observations suggest that deep icequakes are due to hydraulic fracturing, and that they can be used to track fluid flow inside glaciers
Electro-Magnetic Earthquake Bursts and Critical Rupture of Peroxy Bond Networks in Rocks
We propose a mechanism for the low frequency electromagnetic emissions and
other electromagnetic phenomena which have been associated with earthquakes.
The mechanism combines the critical earthquake concept and the concept of crust
acting as a charging electric battery under increasing stress. The electric
charges are released by activation of dormant charge carriers in the oxygen
anion sublattice, called peroxy bonds or positive hole pairs (PHP), where a PHP
represents an with ,
i.e. an in a matrix of of silicates. We propose that PHP are
activated by plastic deformations during the slow cooperative build-up of
stress and the increasingly correlated damage culminating in a large
``critical'' earthquake. Recent laboratory experiments indeed show that
stressed rocks form electric batteries which can release their charge when a
conducting path closes the equivalent electric circuit. We conjecture that the
intermittent and erratic occurrences of EM signals are a consequence of the
progressive build-up of the battery charges in the Earth crust and their
erratic release when crack networks are percolating throughout the stressed
rock volumes, providing a conductive pathway for the battery currents to
discharge. EM signals are thus expected close to the rupture, either slightly
before or after, that is, when percolation is most favored.Comment: 17 pages with 3 figures, extended discussion with 1 added figure and
162 references. The new version provides both a synthesis of two theories and
a review of the fiel
Ants in a Labyrinth: A Statistical Mechanics Approach to the Division of Labour
Division of labour (DoL) is a fundamental organisational principle in human
societies, within virtual and robotic swarms and at all levels of biological
organisation. DoL reaches a pinnacle in the insect societies where the most
widely used model is based on variation in response thresholds among
individuals, and the assumption that individuals and stimuli are well-mixed.
Here, we present a spatially explicit model of DoL. Our model is inspired by
Pierre de Gennes' 'Ant in a Labyrinth' which laid the foundations
of an entire new field in statistical mechanics. We demonstrate the emergence,
even in a simplified one-dimensional model, of a spatial patterning of
individuals and a right-skewed activity distribution, both of which are
characteristics of division of labour in animal societies. We then show using a
two-dimensional model that the work done by an individual within an activity
bout is a sigmoidal function of its response threshold. Furthermore, there is an
inverse relationship between the overall stimulus level and the skewness of the
activity distribution. Therefore, the difference in the amount of work done by
two individuals with different thresholds increases as the overall stimulus
level decreases. Indeed, spatial fluctuations of task stimuli are minimised at
these low stimulus levels. Hence, the more unequally labour is divided amongst
individuals, the greater the ability of the colony to maintain homeostasis.
Finally, we show that the non-random spatial distribution of individuals within
biological and social systems could be caused by indirect (stigmergic)
interactions, rather than direct agent-to-agent interactions. Our model links
the principle of DoL with principles in the statistical mechanics and provides
testable hypotheses for future experiments
A Comprehensive Expression Profile of MicroRNAs in Porcine Pituitary
MicroRNAs (miRNAs) are an abundant class of small RNAs that regulate expressions of most genes. miRNAs play important roles in the pituitary, the “master” endocrine organ.However, we still don't know which role miRNAs play in the development of pituitary tissue or how much they contribute to the pituitary function. By applying a combination of microarray analysis and Solexa sequencing, we detected a total of 450 miRNAs in the porcine pituitary. Verification with RT-PCR showed a high degree of confidence for the obtained data. According to the current miRBase release17.0, the detected miRNAs included 169 known porcine miRNAs, 163 conserved miRNAs not yet identified in the pig, and 12 potentially new miRNAs not yet identified in any species, three of which were revealed using Northern blot. The pituitary might contain about 80.17% miRNA types belonging to the animal. Analysis of 10 highly expressed miRNAs with the Kyoto Encyclopedia of Genes and Genomes (KEGG) indicated that the enriched miRNAs were involved not only in the development of the organ but also in a variety of inter-cell and inner cell processes or pathways that are involved in the function of the organ
Recombinant human growth hormone and insulin-like growth factor-1 do not affect mitochondrial derived highly reactive oxygen species production in peripheral blood mononuclear cells under conditions of substrate saturation in-vitro
MicroRNA networks direct neuronal development and plasticity
MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-transcriptional regulators of gene expression. In neurons, the functions of individual miRNAs are just beginning to emerge, and recent studies have elucidated roles for neural miRNAs at various stages of neuronal development and maturation, including neurite outgrowth, dendritogenesis, and spine formation. Notably, miRNAs regulate mRNA translation locally in the axosomal and synaptodendritic compartments, and thereby contribute to the dynamic spatial organization of axonal and dendritic structures and their function. Given the critical role for miRNAs in regulating early brain development and in mediating synaptic plasticity later in life, it is tempting to speculate that the pathology of neurological disorders is affected by altered expression or functioning of miRNAs. Here we provide an overview of recently identified mechanisms of neuronal development and plasticity involving miRNAs, and the consequences of miRNA dysregulation
Brain energy rescue:an emerging therapeutic concept for neurodegenerative disorders of ageing
The brain requires a continuous supply of energy in the form of ATP, most of which is produced from glucose by oxidative phosphorylation in mitochondria, complemented by aerobic glycolysis in the cytoplasm. When glucose levels are limited, ketone bodies generated in the liver and lactate derived from exercising skeletal muscle can also become important energy substrates for the brain. In neurodegenerative disorders of ageing, brain glucose metabolism deteriorates in a progressive, region-specific and disease-specific manner — a problem that is best characterized in Alzheimer disease, where it begins presymptomatically. This Review discusses the status and prospects of therapeutic strategies for countering neurodegenerative disorders of ageing by improving, preserving or rescuing brain energetics. The approaches described include restoring oxidative phosphorylation and glycolysis, increasing insulin sensitivity, correcting mitochondrial dysfunction, ketone-based interventions, acting via hormones that modulate cerebral energetics, RNA therapeutics and complementary multimodal lifestyle changes
The Electrochemical Performance and Applications of Several Popular Lithium-ion Batteries for Electric Vehicles - A Review
The Lithium-ion battery is one of the most common batteries used in Electric Vehicles (EVs) due to the specific features of high energy density, power density, long life span and environment friendly. With the development of lithium-ion battery technology, different materials have been adopted in the design of the cathodes and anodes in order to gain a better performance. , , , and are five common lithium-ion batteries adopted in commercial EVs nowadays. The characteristics of these five lithium-ion batteries are reviewed and compared in the aspects of electrochemical performance and their practical applications
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