Successful pregnancy outcome in a case of idiopathic primary hypoparathyroidism with seizure disorder: a case report

Hypoparathyroidism, a disorder of low parathyroid hormones resulting in hypocalcemia and hyperphosphatemia, is relatively a rare occurrence in pregnancy. Nevertheless, it has been reported to cause significant maternal and neonatal morbidity and even mortality in severe cases. Dynamic changes in serum calcium during pregnancy superimposed with the inherent defect in the parathyroid gland and calcium metabolism in these patients make it even more difficult to monitor and manage the patient. We report a case of idiopathic primary hypoparathyroidism with seizure disorder, managed with aggressive monitoring and timely decision making, resulting in a favorable outcome

Electro-Magnetic Earthquake Bursts and Critical Rupture of Peroxy Bond Networks in Rocks

We propose a mechanism for the low frequency electromagnetic emissions and other electromagnetic phenomena which have been associated with earthquakes. The mechanism combines the critical earthquake concept and the concept of crust acting as a charging electric battery under increasing stress. The electric charges are released by activation of dormant charge carriers in the oxygen anion sublattice, called peroxy bonds or positive hole pairs (PHP), where a PHP represents an $O_3X/^{OO}\backslash YO_3$ with $X,Y = Si^{4+}, Al^{3+}...$, i.e. an $O^-$ in a matrix of $O^{2-}$ of silicates. We propose that PHP are activated by plastic deformations during the slow cooperative build-up of stress and the increasingly correlated damage culminating in a large ``critical'' earthquake. Recent laboratory experiments indeed show that stressed rocks form electric batteries which can release their charge when a conducting path closes the equivalent electric circuit. We conjecture that the intermittent and erratic occurrences of EM signals are a consequence of the progressive build-up of the battery charges in the Earth crust and their erratic release when crack networks are percolating throughout the stressed rock volumes, providing a conductive pathway for the battery currents to discharge. EM signals are thus expected close to the rupture, either slightly before or after, that is, when percolation is most favored.Comment: 17 pages with 3 figures, extended discussion with 1 added figure and 162 references. The new version provides both a synthesis of two theories and a review of the fiel

Variations of the ionospheric electron density during the Bhuj seismic event

Ionospheric perturbations by natural geophysical activity, such as volcanic eruptions and earthquakes, have been studied since the great Alaskan earthquake in 1964. Measurements made from the ground show a variation of the critical frequency of the ionosphere layers before and after the shock. In this paper, we present an experimental investigation of the electron density variations around the time of the Bhuj earthquake in Gujarat, India. Several experiments have been used to survey the ionosphere. Measurements of fluctuations in the integrated electron density or TEC (Total Electron Content) between three satellites (TOPEX-POSEIDON, SPOT2, SPOT4) and the ground have been done using the DORIS beacons. TEC has been also evaluated from a ground-based station using GPS satellites, and finally, ionospheric data from a classical ionospheric sounder located close to the earthquake epicenter are utilized. Anomalous electron density variations are detected both in day and night times before the quake. The generation mechanism of these perturbations is explained by a modification of the electric field in the global electric circuit induced during the earthquake preparation. Key words. Ionosphere (ionospheric disturbances) – Radio Science (ionospheric physics) – History of geophysics (seismology

Outcome of different cerclage methods in two cases of congenital cervical insufficiency: a case report

Cervical insufficiency (CI) or progressive shortening and thinning of cervix is a contributor to perinatal mortality through spontaneous mid-trimester miscarriages or early preterm birth. Congenital factors for cervical insufficiency are rarer than acquired factors. The lack of definitive criteria or methods is a challenge for diagnosis of such cases. Different cerclage methods and timely cerclage have shown to improve the outcome of pregnancy in patients with congenital cervical insufficiency (CCI). Here, we report two cases of CCI managed with different methods of cerclage culminating in successful pregnancy outcomes

tert-Butyl 3-(8-bromo-4H,10H-1,2-oxazolo[4,3-c][1]benzoxepin-10-yl)-2-methyl-1H-indole-1-carboxylate

In the title compound, C25H23BrN2O4, the seven-membered ring adopts a twisted-boat conformation. The indole ring system is planar within 0.021 (2) Å and the ester group [–C(=O)—O—C–] is almost coplanar with it [dihedral angle = 3.0 (2)°]. The conformation of the ester group is influenced by intramolecular C—H...O interactions. In the crystal structure, molecules are linked into chains along the b axis by C—H...N hydrogen bonds

Investigation of Total Electron Content Variability Due to Seismic and Geomagnetic Disturbances in the Lonosphere

Variations in solar, geomagnetic, and seismic activity can cause deviations in the ionospheric plasma that can be detected as disturbances in both natural and man-made signals. Total electron content (TEC) is an efficient means for investigating the structure of the ionosphere by making use of GPS receivers. In this study, TEC data obtained for eight GPS stations are compared with each other using the cross-correlation coefficient (CC), symmetric Kullback-Leibler distance (KLD), and L2 norm (L2N) for quiet days of the ionosphere, during severe geomagnetic storms and strong earthquakes. It is observed that only KLD and L2N can differentiate the seismic activity from the geomagnetic disturbance and quiet ionosphere if the stations are in a radius of 340 km. When TEC for each station is compared with an average quiet day TEC for all periods using CC, KLD, and L2N, it is observed that, again, only KLD and L2N can distinguish the approaching seismicity for stations that are within 150 km radius to the epicenter. When the TEC of consecutive days for each station and for all periods are compared, it is observed that CC, KLD, and L2N methods are all successful in distinguishing the geomagnetic disturbances. Using sliding-window statistical analysis, moving averages of daily TEC with estimated variance bounds are also obtained for all stations and for all days of interest. When these bounds are compared with each other for all periods, it is observed that CC, KLD, and L2N are successful tools for detecting ionospheric disturbances.Wo