25 research outputs found

    Interplay of quark and meson degrees of freedom in a near-threshold resonance: multi-channel case

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    We investigate the interplay of quark and meson degrees of freedom in a physical state representing a near-threshold resonance for the case of multiple continuum channels. The aim is to demonstrate the full complexity of near-threshold phenomena. It turns out that those are especially rich, if both quark and meson dynamics generate simultaneously weakly coupled near-threshold poles in the S-matrix. We study the properties of this scenario in detail, such as t-matrix and production amplitude zeros, as well as various effects of the continuum channels interplay.Comment: LaTeX2e, 10 pages, version to appear in Eur.Phys.J.

    Alignment of the CMS silicon tracker during commissioning with cosmic rays

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    This is the Pre-print version of the Article. The official published version of the Paper can be accessed from the link below - Copyright @ 2010 IOPThe CMS silicon tracker, consisting of 1440 silicon pixel and 15 148 silicon strip detector modules, has been aligned using more than three million cosmic ray charged particles, with additional information from optical surveys. The positions of the modules were determined with respect to cosmic ray trajectories to an average precision of 3–4 microns RMS in the barrel and 3–14 microns RMS in the endcap in the most sensitive coordinate. The results have been validated by several studies, including laser beam cross-checks, track fit self-consistency, track residuals in overlapping module regions, and track parameter resolution, and are compared with predictions obtained from simulation. Correlated systematic effects have been investigated. The track parameter resolutions obtained with this alignment are close to the design performance.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)

    Commissioning and performance of the CMS pixel tracker with cosmic ray muons

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    This is the Pre-print version of the Article. The official published verion of the Paper can be accessed from the link below - Copyright @ 2010 IOPThe pixel detector of the Compact Muon Solenoid experiment consists of three barrel layers and two disks for each endcap. The detector was installed in summer 2008, commissioned with charge injections, and operated in the 3.8 T magnetic field during cosmic ray data taking. This paper reports on the first running experience and presents results on the pixel tracker performance, which are found to be in line with the design specifications of this detector. The transverse impact parameter resolution measured in a sample of high momentum muons is 18 microns.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)

    Performance of the CMS drift-tube chamber local trigger with cosmic rays

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    The performance of the Local Trigger based on the drift-tube system of the CMS experiment has been studied using muons from cosmic ray events collected during the commissioning of the detector in 2008. The properties of the system are extensively tested and compared with the simulation. The effect of the random arrival time of the cosmic rays on the trigger performance is reported, and the results are compared with the design expectations for proton-proton collisions and with previous measurements obtained with muon beams

    Performance of the CMS Level-1 trigger during commissioning with cosmic ray muons and LHC beams

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    This is the Pre-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2010 IOPThe CMS Level-1 trigger was used to select cosmic ray muons and LHC beam events during data-taking runs in 2008, and to estimate the level of detector noise. This paper describes the trigger components used, the algorithms that were executed, and the trigger synchronisation. Using data from extended cosmic ray runs, the muon, electron/photon, and jet triggers have been validated, and their performance evaluated. Efficiencies were found to be high, resolutions were found to be good, and rates as expected.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)

    Performance of the CMS hadron calorimeter with cosmic ray muons and LHC beam data

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    This is the Pre-print version of the Article. The official published version of the Paper can be accessed from the link below - Copyright @ 2010 IOPThe CMS Hadron Calorimeter in the barrel, endcap and forward regions is fully commissioned. Cosmic ray data were taken with and without magnetic field at the surface hall and after installation in the experimental hall, hundred meters underground. Various measurements were also performed during the few days of beam in the LHC in September 2008. Calibration parameters were extracted, and the energy response of the HCAL determined from test beam data has been checked.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)

    Performance of the CMS Level-1 trigger during commissioning with cosmic ray muons and LHC beams

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    This is the Pre-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2010 IOPThe CMS Level-1 trigger was used to select cosmic ray muons and LHC beam events during data-taking runs in 2008, and to estimate the level of detector noise. This paper describes the trigger components used, the algorithms that were executed, and the trigger synchronisation. Using data from extended cosmic ray runs, the muon, electron/photon, and jet triggers have been validated, and their performance evaluated. Efficiencies were found to be high, resolutions were found to be good, and rates as expected.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)

    Performance study of the CMS barrel resistive plate chambers with cosmic rays

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    This is the Pre-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2010 IOPIn October and November 2008, the CMS collaboration conducted a programme of cosmic ray data taking, which has recorded about 270 million events. The Resistive Plate Chamber system, which is part of the CMS muon detection system, was successfully operated in the full barrel. More than 98% of the channels were operational during the exercise with typical detection efficiency of 90%. In this paper, the performance of the detector during these dedicated runs is reported.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)

    Psa-nadir At 1 Year As A Sound Contemporary Prognostic Factor For Low-dose-rate Iodine-125 Seeds Brachytherapy

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    Objectives: To identify predictors of outcomes in patients with localized prostate cancer treated with iodine-125 brachytherapy in a longitudinal uncontrolled study. Methods: Between 2000 and 2011, 560 histologically confirmed patients were treated with brachytherapy of whom 305 with ≥24-month follow-up and localized tumor were evaluated after exclusion of those locally advanced and under androgen ablation. Results: Patients' mean age was 63.93 years (44-88), mean pretreatment prostate-specific antigen (PSA) was 6.34 ng/mL (0.67-33.09), overall median follow-up was 75.35 months (24-158.37), biochemical recurrence occurred in 17 patients (5.57 %), cancer-specific survival was 100 %, and overall survival was 98.03 %. At multivariate analyses, only PSA-nadir at 1 year and age were related to disease-free survival: To each unit of PSA-nadir, the risk increases 87.3 %-OR 1.87 (p 70)-OR 4.69 (p = 0.04; 95 % CI 1.39-18.47). Best cutoff for PSA-nadir at one year was 0.285 (AUC = 0.78; p < 0.001; 95 % CI 0.68-0.89). Kaplan-Meier analysis confirmed PSA-nadir (p < 0.001) as prognostic, while D'Amico's classification failed (p = 0.24). No grade 3 or 4 complication was reported, and only 31.4 % of patients had grade 2 urinary or rectal toxicity. PSA bounce ≥0.4 ng/mL occurred in 18.4 % with no impact on biochemical recurrence. Conclusions: Half (50.49 %) of patients in the scenario of localized prostate cancer treated with iodine-125 brachytherapy reach PSA-nadir at 1 year <0.285, recognized as a key independent prognostic factor. Graphical Abstract: [Receiver Operating Characteristic curve analysis for PSA-nadir at 1 year] [Figure not available: see fulltext.] © 2013 Springer-Verlag Berlin Heidelberg.323753759Merrick, G.S., Butler, W.M., Dorsey, A.T., Galbreath, R.W., Blatt, H., Lief, J.H., Rectal function following prostate brachytherapy (2000) Int J Radiat Oncol Biol Phys, 48 (3), pp. 667-674Sylvester, J.E., Grimm, P.D., Wong, J., Galbreath, R.W., Merrick, G., Blasko, J.C., Fifteen-year biochemical relapse-free survival, cause-specific survival, and overall survival following I (125) prostate brachytherapy in clinically localized prostate cancer: Seattle experience (2011) Int J Radiat Oncol Biol Phys, 81 (2), pp. 376-381Vigneri, P., Herati, A.S., Potters, L., The second decade of prostate brachytherapy: evidence and cost based outcomes (2010) Urol Oncol, 28 (1), pp. 86-90Roach III, M., Hanks, G., Thames Jr., H., Schellhammer, P., Shipley, W.U., Sokol, G.H., Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO phoenix consensus conference (2006) Int J Radiat Oncol Biol Phys, 65 (4), pp. 965-974Rivard, M.J., Butler, W.M., Devlin, P.M., Hayes Jr., J.K., Hearn, R.A., Lief, E.P., Meigooni, A.S., Williamson, J.F., American Brachytherapy Society recommends no change for prostate permanent implant dose prescriptions using iodine-125 or palladium-103 (2007) Brachytherapy, 6 (1), pp. 34-37Potters, L., Morgenstern, C., Calugaru, E., Fearn, P., Jassal, A., Presser, J., 12-year outcomes following permanent prostate brachytherapy in patients with clinically localized prostate cancer (2008) J Urol, 179 (5 SUPPL.), pp. S20-S24Stock, R.G., Cesaretti, J.A., Stone, N.N., Disease-specific survival following the brachytherapy management of prostate cancer (2006) Int J Radiat Oncol Biol Phys, 64 (3), pp. 810-816Stock, R.G., Cesaretti, J.A., Unger, P., Stone, N.N., Distant and local recurrence in patients with biochemical failure after prostate brachytherapy (2008) Brachytherapy, 7 (3), pp. 217-222Ko, E.C., Stone, N.N., Stock, R.G., PSA-nadir of <0.5 ng/mL following brachytherapy for early-stage prostate adenocarcinoma is associated with freedom from prostate-specific antigen failure (2012) Int J Radiat Oncol Biol Phys, 83 (2), pp. 600-607Taira, A.V., Merrick, G.S., Galbreath, R.W., Wallner, K.E., Butler, W.M., Natural history of clinically staged low- and intermediate-risk prostate cancer treated with monotherapeutic permanent interstitial brachytherapy (2010) Int J Radiat Oncol Biol Phys, 76 (2), pp. 349-354Taira, A.V., Merrick, G.S., Butler, W.M., Galbreath, R.W., Lief, J., Adamovich, E., Long-term outcome for clinically localized prostate cancer treated with permanent interstitial brachytherapy (2011) Int J Radiat Oncol Biol Phys, 79 (5), pp. 1336-1342Stone, N.N., Stock, R.G., Unger, P., Intermediate term biochemical-free progression and local control following 125 iodine brachytherapy for prostate cancer (2005) J Urol, 173 (3), pp. 803-807Zelefsky, M.J., Kuban, D.A., Levy, L.B., Potters, L., Beyer, D.C., Blasko, J.C., Multi-institutional analysis of long-term outcome for stages T1-T2 prostate cancer treated with permanent seed implantation (2007) Int J Radiat Oncol Biol Phys, 67 (2), pp. 327-333Bowes, D., Crook, J.M., Wallace, K., Evans, A., Toi, A., Finelli, A., Jewett, M.A., Catton, C., Results of a surgically derived nomogram to predict Gleason score upgrading applied to a cohort of patients with "favorable-risk" prostate cancer treated with permanent seed brachytherapy (2012) Urology, 80 (3), pp. 649-655Stokes, S.H., Real, J.D., Adams, P.W., Clements, J.C., Wuertzer, S., Kan, W., Transperineal ultrasound-guided radioactive seed implantation for organ-confined carcinoma of the prostate (1997) Int J Radiat Oncol Biol Phys, 37 (2), pp. 337-341Guarneri, A., Botticella, A., Ragona, R., Filippi, A.R., Munoz, F., Casetta, G., Gontero, P., Ricardi, U., Prostate-specific antigen kinetics after I 125-brachytherapy for prostate adenocarcinoma (2013) World J Urol, 31 (2), pp. 411-415Storey, M.R., Landgren, R.C., Cottone, J.L., Stallings, J.W., Logan, C.W., Fraiser, L.P., Transperineal 125 iodine implantation for treatment of clinically localized prostate cancer: 5-year tumor control and morbidity (1999) Int J Radiat Oncol Biol Phys, 43 (3), pp. 565-567Shapiro, E.Y., Rais-Bahrami, S., Morgenstern, C., Napolitano, B., Richstone, L., Potters, L., Long-term outcomes in younger men following permanent prostate brachytherapy (2009) J Urol., 181 (4), pp. 1665-1671. , Discussion 71Burri, R.J., Ho, A.Y., Forsythe, K., Cesaretti, J.A., Stone, N.N., Stock, R.G., Young men have equivalent biochemical outcomes compared with older men after treatment with brachytherapy for prostate cancer (2010) Int J Radiat Oncol Biol Phys, 77 (5), pp. 1315-1321Merrick, G.S., Wallner, K.E., Galbreath, R.W., Butler, W.M., Brammer, S.G., Allen, Z.A., Biochemical and functional outcomes following brachytherapy with or without supplemental therapies in men < or =50 years of age with clinically organ-confined prostate cancer (2008) Am J Clin Oncol, 31 (6), pp. 539-544Abdel-Wahab, M., Reis, I.M., Hamilton, K., Second primary cancer after radiotherapy for prostate cancer-a SEER analysis of brachytherapy versus external beam radiotherapy (2008) Int J Radiat Oncol Biol Phys, 72 (1), pp. 58-6
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