CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe

Primary Diagnosis of Marfan Syndrome in Pregnant 16 Years Old Girl: a Clinical Case

Background. Marfan syndrome is autosomal dominant hereditary disease of connective tissue with involvement of cardiovascular and musculoskeletal systems and eyes. Pregnancy in patients with Marfan syndrome differs with high risk of complications in mother and fetus, therefore it merits special attention from clinicians.Clinical Case Description. Patient M., 16 years old applied to the maternity obstetric service at gestational age 19/20 weeks. From anamnesis: aortic dilatation at sinuses of Valsalva, subaortic stenosis, mitral valve prolapse stage II, mitral valve insufficiency stage II, tricuspid valve prolapse stage I. Patient height was 179 cm and weight was 60 kg. There is data in medical records on diagnosed lens subluxation, scoliosis, funnel chest, flat feet, dental crowding in different years. Considering all the mentioned symptoms we have thought of Marfan syndrome diagnosis. We have performed therapy for enhancement of uteroplacental blood flow (intrauterine growth restriction was revealed). The vaginal pessary has been implanted at 28th week of gestation dueto cervical insufficiency. The patient received beta1-blocker. Vaginal delivery at 37 weeks 3 days. The girl was born, body weightwas 2230 g and height was 43 cm, 7/8 on APGAR scale.Conclusion. The patient was followed up by a cardiologist, orthopaedist, ophthalmologist and dentist with different symptom complexes from an early age. Though it was possible to determine correct diagnosis only at the age of 16 years during the examination due to unintended pregnancy. All clinicians have to remember that combination of cardiovascularsystem damages, lens subluxation and orthopaedic problems in tall and thin patients can be indicative of Marfan syndrome

NEW METHOD OF PREVENTION OF IRONDEFENSE ANEMIA IN PREGNANT TEENS

The paper presents an assessment of the effectiveness of the method proposed by the authors for the prevention of iron deficiency anemia in minor pregnant women. In the first stage, 593 histories of childbirth were retrospectively analyzed (group 1 — minors 13-15 years (n = 49), 2 group — minors 16-17 (n = 434), 3rd group — middle reproductive age (n = 110) ). In the second stage, a prospective study of the frequency and structure of anemia of pregnant women was carried out (group 1 — minors aged 13-15 years (n = 17), group 2 — minors 16-17 (n = 127), 3rd group — women of middle reproductive age (n = 110)). At the III stage, minor pregnant women were divided into two groups: in 1 (main) group (n = 144), iron deficiency anemia was prevented according to the method we proposed; in the 2nd group (comparison group) traditional therapy with iron preparations was carried out at the appearance of signs of anemia. The essence of the proposed method is that an minor pregnant woman, without waiting for laboratory signs of anemia, is examined for ferritin in venous blood, and at a value below 35 ng/ml, oral iron preparations are prescribed in conventional preventive doses for a period of 3 months, and if through three months the content of ferritin in the venous blood is again below 35 ng/ml — the intake of iron-containing preparations continues for another 3 months. The use of the proposed method contributed to a significant decrease in the incidence of anemia in minor pregnant women. The proposed method of preventing iron deficiency anemia in minor pregnant women helps to reduce the frequency and severity of anemia in this complex category of patients