321 research outputs found
An analysis of factors influencing in social media and e-communication among younger generation
Humans have always communicated with each other in a number of ways. Human communication was revolutionized formerly with speech, symbols, writing and in the recent time with e-communications and technology. With the advancement of technology, the scenario of communication has changed forever. By way of regular telephone links, private cables, internet access, microwave relayed by communication satellites or by land based repeater stations, many activities which were considered impossible have now become possible. Money can be transferred between banks and across oceans, an entire manufacturing facility can be monitored without the need of physical presence through tele-computing or software and data can be shared and distributed to innumerable people over long distances almost instantly. All these activities have been made possible by the development of various technological tools like telephones, voicemail, cellular phones, facsimiles, internet, emails, blogs and many other types of soft wares available for composing, transmitting and sharing data. Thus, the evolution of communication has been truly phenomenal and the use of technology enabled communication has and will continue to open new frontiers in the days to come. These new possibilities also bring along new opportunities and challenges.In this paper, through an empirical study, an effort is made to find out the analysis of factors influencing in social media and e - communication on the younger generation. Questionnaire method is adopted for data collection and statistical tools used for analysis include Mean, Ranking and ANOVA. Data is interpreted and ideas for factors influencing in social media and e - communication on the younger generation. Finally give the suggestions and conclusion
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Interfacial coatings for ceramic-matrix composites -- Volume 2. Final report
This report summarizes the task conducted to examine various activities on interface development for ceramic-matrix composites (CMCs) intended for high-temperature applications. While several articles have been published on the subject of CMC interfaces, the purpose of this report is to describe the various ongoing efforts on interface concepts, material selection, and issues related to processing methods employed for developing interface coatings. The most exciting and new development in the field is the discovery of monazite as a potential interface material for mullite- and alumina-based composites. Monazite offers two critical properties to the CMC system; a weakly bonded layer due to its non-wetting behavior and chemical compatibility with both alumina and mullite up to very high temperatures (> 1,600 C). Other interesting concepts with intensive material development efforts are also being pursued and a brief discussion of these are given in the main text. While demonstration of new interface concepts seems to be the primary objective in most studies, difficulties in processing of interface coatings and designing reliable test methods for determining interface properties have actually retarded the progress. Some of the concepts appear to be simple in nature but require sophisticated processing schemes to develop the coatings. Multilayered coatings with each layer serving specific function are also being proposed. Recent studies also show that significant degradation in fiber strength (30--50%) can result from merely applying the interface coating. These factors have compounds the complexity of interface tailoring in CMCs leading to a need for specific solution for a specific CMC system
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Ceramic Component Development Process Analysis
The development of ceramic components and coatings is critical to the demonstration of advanced fossil energy systems. Ceramic components and coating will play critical role in hot-gas filtration, high- temperature heat exchangers, thermal barrier coatings, and the hot- section of turbines. Continuous-fiber composites (CFCC) are expected to play an increasing role in these applications. This program encompassed five technical areas related to ceramic component development for fossil energy systems
A conservative coupling algorithm between a compressible flow and a rigid body using an Embedded Boundary method
This paper deals with a new solid-fluid coupling algorithm between a rigid
body and an unsteady compressible fluid flow, using an Embedded Boundary
method. The coupling with a rigid body is a first step towards the coupling
with a Discrete Element method. The flow is computed using a Finite Volume
approach on a Cartesian grid. The expression of numerical fluxes does not
affect the general coupling algorithm and we use a one-step high-order scheme
proposed by Daru and Tenaud [Daru V,Tenaud C., J. Comput. Phys. 2004]. The
Embedded Boundary method is used to integrate the presence of a solid boundary
in the fluid. The coupling algorithm is totally explicit and ensures exact mass
conservation and a balance of momentum and energy between the fluid and the
solid. It is shown that the scheme preserves uniform movement of both fluid and
solid and introduces no numerical boundary roughness. The effciency of the
method is demonstrated on challenging one- and two-dimensional benchmarks
Molecular and cellular mechanisms underlying the evolution of form and function in the amniote jaw.
The amniote jaw complex is a remarkable amalgamation of derivatives from distinct embryonic cell lineages. During development, the cells in these lineages experience concerted movements, migrations, and signaling interactions that take them from their initial origins to their final destinations and imbue their derivatives with aspects of form including their axial orientation, anatomical identity, size, and shape. Perturbations along the way can produce defects and disease, but also generate the variation necessary for jaw evolution and adaptation. We focus on molecular and cellular mechanisms that regulate form in the amniote jaw complex, and that enable structural and functional integration. Special emphasis is placed on the role of cranial neural crest mesenchyme (NCM) during the species-specific patterning of bone, cartilage, tendon, muscle, and other jaw tissues. We also address the effects of biomechanical forces during jaw development and discuss ways in which certain molecular and cellular responses add adaptive and evolutionary plasticity to jaw morphology. Overall, we highlight how variation in molecular and cellular programs can promote the phenomenal diversity and functional morphology achieved during amniote jaw evolution or lead to the range of jaw defects and disease that affect the human condition
What About my Privacy, Habibi? Understanding Privacy Concerns and Perceptions of Users From Different Socioeconomic Groups in the Arab World
This paper contributes an in-depth understanding of privacy concerns and perceptions of Arab users. We report on the first comparison of privacy perceptions among (1) users from high socioeconomic groups in Arab countries (HSA), (2) users from medium to low socioeconomic groups in Arab countries (LSA), and (3) as a baseline, users from high socioeconomic groups in Germany (HSG). Our work is motivated by the fact that most research in privacy focused on Western, Educated, Industrialized, Rich, and Democratic (WEIRD) societies. This excludes a segment of the population whose cultural norms and socioeconomic status influence privacy perception and needs. We report on multiple novel findings and unexpected similarities and differences across the user groups. For example, shoulder surfing is more common across LSA and HSG, and defamation is a major threat in LSA. We discuss the implications of our findings on the design of privacy protection measures for investigated groups
Decellularised skeletal muscles allow functional muscle regeneration by promoting host cell migration
Pathological conditions affecting skeletal muscle function may lead to irreversible volumetric
muscle loss (VML). Therapeutic approaches involving acellular matrices represent an
emerging and promising strategy to promote regeneration of skeletal muscle following injury.
Here we investigated the ability of three different decellularised skeletal muscle scaffolds to
support muscle regeneration in a xenogeneic immune-competent model of VML, in which
the EDL muscle was surgically resected. All implanted acellular matrices, used to replace
the resected muscles, were able to generate functional artificial muscles by promoting host
myogenic cell migration and differentiation, as well as nervous fibres, vascular networks, and
satellite cell (SC) homing. However, acellular tissue mainly composed of extracellular matrix
(ECM) allowed better myofibre three-dimensional (3D) organization and the restoration of
SC pool, when compared to scaffolds which also preserved muscular cytoskeletal
structures. Finally, we showed that fibroblasts are indispensable to promote efficient
migration and myogenesis by muscle stem cells across the scaffolds in vitro. This data strongly support the use of xenogeneic acellular muscles as device to treat VML conditions in absence of donor cell implementation, as well as in vitro model for studying cell interplay during myogenesis
The aged niche disrupts muscle stem cell quiescence
SUMMARY The niche is a conserved regulator of stem cell quiescence and function. During aging, stem cell function declines. To what extent and by which means age-related changes within the niche contribute to this phenomenon are unknown. We demonstrate that the aged muscle stem cell niche, the muscle fiber, expresses FGF2 under homeostatic conditions, driving a subset of satellite cells to break quiescence and lose self-renewing capacity. We show that relatively dormant aged satellite cells robustly express Sprouty1 (spry1), an inhibitor of FGF signalling. Increasing FGF signalling in aged satellite cells under homeostatic conditions by removing spry1, results in the loss of quiescence, satellite cell depletion and diminished regenerative capacity. Conversely, reducing niche-derived FGF activity through inhibition of FGFR1 signalling or overexpression of spry1 in satellite cells prevents their depletion. These experiments identify an age-dependent change in the stem cell niche that directly influences stem cell quiescence and function
Oncorhynchus mykiss pax7 sequence variations with comparative analyses against other teleost species
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