9 research outputs found
Nuevas aportaciones corológicas para la amenazada Isoetes durieui Bory (Isoetaceae, Pteridophyta) en la provincia de Huelva (Andalucía, España)
Flora de interés corológico para Andalucía occidental
Flora of chorologycal interest for Western AndalusiaPalabras clave. Corología, Biogeografía, Andalucía Occidental, España.Key words. Chorology, Biogeography, Western Andalusia, Spain
New chorologic contributions to the endangered Isoetes durieui Bory (Isoetaceae, Pteridophyta) in the province of Huelva (Andalusia, Spain)
Role of age and comorbidities in mortality of patients with infective endocarditis
[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality.
[Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk.
[Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality.
[Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group
The reference site collaborative network of the european innovation partnership on active and healthy ageing
Seventy four Reference Sites of the European Innovation
Partnership on Active and Healthy Ageing (EIP on AHA)
have been recognised by the European Commission in
2016 for their commitment to excellence in investing and
scaling up innovative solutions for active and healthy
ageing. The Reference Site Collaborative Network
(RSCN) brings together the EIP on AHA Reference Sites
awarded by the European Commission, and Candidate
Reference Sites into a single forum. The overarching goals
are to promote cooperation, share and transfer good
practice and solutions in the development and scaling up
of health and care strategies, policies and service delivery
models, while at the same time supporting the action
groups in their work. The RSCN aspires to be recognized
by the EU Commission as the principal forum and
authority representing all EIP on AHA Reference Sites.
The RSCN will contribute to achieve the goals of the EIP
on AHA by improving health and care outcomes for
citizens across Europe, and the development of sustainable
economic growth and the creation of jobs
Assessment and Monitoring Protocols to Guarantee the Maintenance of Biodiversity in Certified Forests: A Case Study for FSC (Forest Stewardship Council) Forests in Southwestern Spain
(1) Biodiversity, sustainable development and nature conservation are fundamental issues nowadays. All companies, administrations, governments and international organisations take these issues into consideration. Sustainable forest management always requires a compromise between profitability and conservation and in this fragile equilibrium, forest certification plays a key scheme. This sustainable management is of great importance in the European Union (EU), with the Forest Stewardship Council playing a fundamental role in forest certification. This certification forms the basis of the ecosystem conservation and improvement strategy in Ence, Energía y Celulosa, the leading company dedicated to the production of eucalyptus in Spain; (2) A three-phase protocol (identification of High Conservation Values, assessment of conservation areas and monitoring program), has been developed, providing clear, objective criteria, particularly concerning FSC (Forest Stewardship Council) Principle 9, the primary goal being the development and application of these objective criteria in the Ence conservation areas in the province of Huelva (Spain). One of the main criteria for habitat classification was correspondence with the habitats listed in Annex I of the Habitats Directive. The compatibility between forest exploitation management and conservation proposed by the Natura 2000 network encouraged us to use this methodology for the identification, classification and assessment of High Conservation Values considered in FSC forest certification: Principle 9; (3) The study encompasses 183 forest management units covering 52,022 ha, with a total of 11,847.45 ha being identified as High Conservation Value Areas. Through the identification and assessment of the conservation areas, the described methodology played a crucial role in demonstrating the positive impact of Ence’s certified forest management on the conservation of biological diversity; (4) This study demonstrates that an objective and reliable identification, assessment and monitoring methodology, with a proven high degree of accuracy in the location and characterisation of interesting and representative habitats in the region, can be implemented. Due to its objectivity, this strategy can be easily applied to other European sustainable forest management sites and possibly to other countries outside the EU
Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort
Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective