Spike burst-pause dynamics of Purkinje cells regulate sensorimotor adaptation

Cerebellar Purkinje cells mediate accurate eye movement coordination. However, it remains unclear how oculomotor adaptation depends on the interplay between the characteristic Purkinje cell response patterns, namely tonic, bursting, and spike pauses. Here, a spiking cerebellar model assesses the role of Purkinje cell firing patterns in vestibular ocular reflex (VOR) adaptation. The model captures the cerebellar microcircuit properties and it incorporates spike-based synaptic plasticity at multiple cerebellar sites. A detailed Purkinje cell model reproduces the three spike-firing patterns that are shown to regulate the cerebellar output. Our results suggest that pauses following Purkinje complex spikes (bursts) encode transient disinhibition of target medial vestibular nuclei, critically gating the vestibular signals conveyed by mossy fibres. This gating mechanism accounts for early and coarse VOR acquisition, prior to the late reflex consolidation. In addition, properly timed and sized Purkinje cell bursts allow the ratio between long-term depression and potentiation (LTD/LTP) to be finely shaped at mossy fibre-medial vestibular nuclei synapses, which optimises VOR consolidation. Tonic Purkinje cell firing maintains the consolidated VOR through time. Importantly, pauses are crucial to facilitate VOR phase-reversal learning, by reshaping previously learnt synaptic weight distributions. Altogether, these results predict that Purkinje spike burst-pause dynamics are instrumental to VOR learning and reversal adaptation.This work was supported by the European Union (www.europa.eu), Project SpikeControl 658479 (recipient NL), the Spanish Agencia Estatal de Investigacio´n and European Regional Development Fund (www.ciencia.gob.es/ portal/site/MICINN/aei), Project CEREBROT TIN2016-81041-R (recipient ER), and the French National Research Agency (www.agence-nationalerecherche. fr) – Essilor International (www.essilor. com), Chair SilverSight ANR-14-CHIN-0001 (recipient AA)

Dynamical masses of the low-mass stellar binary AB Doradus B

Context. ABDoradus is the main system of the ABDoradus moving group. It is a quadruple system formed by two widely separated binaries of pre-main-sequence (PMS) stars: ABDorA/C and ABDor Ba/Bb. The pair ABDorA/C has been extensively studied and its dynamical masses have been determined with high precision, thus making of ABDorC a benchmark for calibrating PMS stellar models. If the orbit and dynamical masses of the pair ABDor Ba/Bb can be determined, they could not only play a similar role to that of ABDorC in calibrating PMS models, but would also help to better understand the dynamics of the whole ABDoradus system. Aims. We aim to determine the individual masses of the pair ABDor Ba/Bb using VLBI observations and archive infrared data, as part of a larger program directed to monitor binary systems in the ABDoradus moving group. Methods. We observed the system ABDor B between 2007 and 2013 with the Australian Long Baseline Array (LBA), at a frequency of 8.4 GHz in phase-reference mode. Results. We detected, for the first time, compact radio emission from both stars in the binary, ABDor Ba and ABDor Bb. This result allowed us to determine the orbital parameters of both the relative and absolute orbits and, consequently, their individual dynamical masses: 0.28±0.05M_sun and 0.25±0.05M_sun, respectively. Conclusions. Comparisons of the dynamical masses with the prediction of PMS evolutionary models show that the models underpredict the dynamical masses of the binary components Ba and Bb by ~30 and 40%, respectively, although they all still agree at the 2-sigma level. The same stellar models favour an age between 50 and 100 Myr for this system. We also discuss the evolutionary status of ABDor Ba/Bb in terms of an earlier double-double star scenario that might explain the strong radio emission detected in both components

23 GHz VLBI Observations of SN 2008ax

We report on phase-referenced 23 GHz Very-Long-Baseline-Interferometry (VLBI) observations of the type IIb supernova SN 2008ax, made with the Very Long Baseline Array (VLBA) on 2 April 2008 (33 days after explosion). These observations resulted in a marginal detection of the supernova. The total flux density recovered from our VLBI image is 0.8$\pm$0.3 mJy (one standard deviation). As it appears, the structure may be interpreted as either a core-jet or a double source. However, the supernova structure could be somewhat confused with a possible close by noise peak. In such a case, the recovered flux density would decrease to 0.48$\pm$0.12 mJy, compatible with the flux densities measured with the VLA at epochs close in time to our VLBI observations. The lowest average expansion velocities derived from our observations are $(1.90 \pm 0.30) \times 10^5$ km s$^{-1}$ (case of a double source) and $(5.2 \pm 1.3) \times 10^4$ km s$^{-1}$ (taking the weaker source component as a spurious, close by, noise peak, which is the more likely interpretation). These velocities are 7.3 and 2 times higher, respectively, than the maximum ejecta velocity inferred from optical-line observations.Comment: 4 pages, 3 figures. Accepted in A&A on 24/03/200

8.4GHz VLBI observations of SN2004et in NGC6946

We report on 8.4GHz Very Long Baseline Interferometry (VLBI) observations of the type II-P supernova SN2004et in the spiral galaxy NGC 6946, made on 20 February 2005 (151 days after explosion). The Very Large Array (VLA) flux density was 1.23$\pm$0.07 mJy, corresponding to an isotropic luminosity at 8.4GHz of (4.45$\pm$0.3)$\times10^{25}$ erg s$^{-1}$ Hz$^{-1}$ and a brightness temperature of (1.3$\pm$0.3)$\times10^{8}$ K. We also provide an improved source position, accurate to about 0.5 mas in each coordinate. The VLBI image shows a clear asymmetry. From model fitting of the size of the radio emission, we estimate a minimum expansion velocity of 15,700$\pm$2,000 km s$^{-1}$. This velocity is more than twice the expected mean expansion velocity estimated from a synchrotron self-absorbed emission model, thus suggesting that synchrotron self-absorption is not relevant for this supernova. With the benefit of an optical spectrum obtained 12 days after explosion, we favor an emission model which consists of two hot spots on an underlying expanding shell of width comparable to that of SN 1993J.Comment: Accepted for publication in A&A (22/05/07

A Decade of SN1993J: Discovery of Wavelength Effects in the Expansion Rate

We have studied the growth of the shell-like radio structure of supernova SN1993J in M81 from September 1993 through October 2003 with very-long-baseline interferometry (VLBI) observations at the wavelengths of 3.6, 6, and 18cm. For this purpose, we have developed a method to accurately determine the outer radius (R) of any circularly symmetric compact radio structure like SN1993J. The source structure of SN1993J remains circularly symmetric (with deviations from circularity under 2%) over almost 4000 days. We characterize the decelerated expansion of SN 1993J through approximately day 1500 after explosion with an expansion parameter $m= 0.845\pm0.005$ ($R \propto t^{m}$). However, from that day onwards the expansion is different when observed at 6 and 18cm. Indeed, at 18cm, the expansion can be well characterized by the same $m$ as before day 1500, while at 6cm the expansion appears more decelerated, and is characterized by another expansion parameter, $m_{6}= 0.788\pm0.015$. Therefore, since about day 1500 on, the radio source size has been progressively smaller at 6cm than at 18cm. These findings are in stark contrast to previous reports by other authors on the details of the expansion. In our interpretation the supernova expands with a single expansion parameter, $m= 0.845\pm0.005$, and the 6cm results beyond day 1500 are due to physical effects, perhaps also coupled to instrumental limitations. Two physical effects may be involved: (a) a changing opacity of the ejecta to the 6cm radiation, and (b) a radial decrease of the magnetic field in the emitting region. (Long abstract cut. Please, read full abstract in manuscript).Comment: 21 pages, 19 figures, accepted in A&

Future mmVLBI Research with ALMA: a European vision

Very long baseline interferometry at millimetre/submillimetre wavelengths (mmVLBI) offers the highest achievable spatial resolution at any wavelength in astronomy. The anticipated inclusion of ALMA as a phased array into a global VLBI network will bring unprecedented sensitivity and a transformational leap in capabilities for mmVLBI. Building on years of pioneering efforts in the US and Europe the ongoing ALMA Phasing Project (APP), a US-led international collaboration with MPIfR-led European contributions, is expected to deliver a beamformer and VLBI capability to ALMA by the end of 2014 (APP: Fish et al. 2013, arXiv:1309.3519). This report focuses on the future use of mmVLBI by the international users community from a European viewpoint. Firstly, it highlights the intense science interest in Europe in future mmVLBI observations as compiled from the responses to a general call to the European community for future research projects. A wide range of research is presented that includes, amongst others: - Imaging the event horizon of the black hole at the centre of the Galaxy - Testing the theory of General Relativity an/or searching for alternative theories - Studying the origin of AGN jets and jet formation - Cosmological evolution of galaxies and BHs, AGN feedback - Masers in the Milky Way (in stars and star-forming regions) - Extragalactic emission lines and astro-chemistry - Redshifted absorption lines in distant galaxies and study of the ISM and circumnuclear gas - Pulsars, neutron stars, X-ray binaries - Testing cosmology - Testing fundamental physical constant

Nut production in Bertholletia excelsa across a logged forest mosaic: implications for multiple forest use

Although many examples of multiple-use forest management may be found in tropical smallholder systems, few studies provide empirical support for the integration of selective timber harvesting with non-timber forest product (NTFP) extraction. Brazil nut (Bertholletia excelsa, Lecythidaceae) is one of the world’s most economically-important NTFP species extracted almost entirely from natural forests across the Amazon Basin. An obligate out-crosser, Brazil nut flowers are pollinated by large-bodied bees, a process resulting in a hard round fruit that takes up to 14 months to mature. As many smallholders turn to the financial security provided by timber, Brazil nut fruits are increasingly being harvested in logged forests. We tested the influence of tree and stand-level covariates (distance to nearest cut stump and local logging intensity) on total nut production at the individual tree level in five recently logged Brazil nut concessions covering about 4000 ha of forest in Madre de Dios, Peru. Our field team accompanied Brazil nut harvesters during the traditional harvest period (January-April 2012 and January-April 2013) in order to collect data on fruit production. Three hundred and ninety-nine (approximately 80%) of the 499 trees included in this study were at least 100 m from the nearest cut stump, suggesting that concessionaires avoid logging near adult Brazil nut trees. Yet even for those trees on the edge of logging gaps, distance to nearest cut stump and local logging intensity did not have a statistically significant influence on Brazil nut production at the applied logging intensities (typically 1–2 timber trees removed per ha). In one concession where at least 4 trees ha-1 were removed, however, the logging intensity covariate resulted in a marginally significant (0.09) P value, highlighting a potential risk for a drop in nut production at higher intensities. While we do not suggest that logging activities should be completely avoided in Brazil nut rich forests, when a buffer zone cannot be observed, low logging intensities should be implemented. The sustainability of this integrated management system will ultimately depend on a complex series of socioeconomic and ecological interactions. Yet we submit that our study provides an important initial step in understanding the compatibility of timber harvesting with a high value NTFP, potentially allowing for diversification of forest use strategies in Amazonian Perù

Condensed Matter Theory of Dipolar Quantum Gases

Recent experimental breakthroughs in trapping, cooling and controlling ultracold gases of polar molecules, magnetic and Rydberg atoms have paved the way toward the investigation of highly tunable quantum systems, where anisotropic, long-range dipolar interactions play a prominent role at the many-body level. In this article we review recent theoretical studies concerning the physics of such systems. Starting from a general discussion on interaction design techniques and microscopic Hamiltonians, we provide a summary of recent work focused on many-body properties of dipolar systems, including: weakly interacting Bose gases, weakly interacting Fermi gases, multilayer systems, strongly interacting dipolar gases and dipolar gases in 1D and quasi-1D geometries. Within each of these topics, purely dipolar effects and connections with experimental realizations are emphasized.Comment: Review article; submitted 09/06/2011. 158 pages, 52 figures. This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Chemical Reviews, copyright American Chemical Society after peer review. To access the final edited and published work, a link will be provided soo