596 research outputs found
Association between gender and receipt of magnetic resonance imaging (MRI) in stroke patients from Puerto Rico
Introduction: Stroke is the fifth principal cause of death in the United States and Puerto Rico and a prime cause of adult disability. Women tend to have worse outcomes post-stroke. Initial diagnoses and management of stroke include the use of computed tomography (CT) and magnetic resonance image (MRI) scans. MRI scans are more sensitive and more specific than CT scans. Still, CT scans are used more commonly. Whether differences in the choice of imaging techniques exists for gender and whether that can be a potential reason for gender differences in post-stroke outcomes it is yet unknown. The study is directed to evaluate the association between gender and receipt of a MRI in stroke patients in the Puerto Rico population. Methods: We did a secondary analysis of data collected from patients who suffered from a stroke and who participated in the Puerto Rican Cardiovascular Surveillance System (PRCSS) in 2007, 2009 and 2011. The main independent variable was gender (male and female). The dependent variable will be receipt of a MRI (alone or in combination with any other imaging modality as recorded in the medical charts). Multivariate logistic regression was used to assess for the independent associations. P-value < 0.05 for a two tailed test was considered to be statistically significant. SPSS software was used for analysis. Results: A total of 1,950 patients suffered from an ischemic stroke and participated at the PRCSS. We excluded 595 patients due to BMI ≥35 (n=135) or no recorded BMI (n=460). MRI was used for 50% of participants. Women were 85% less likely to receive a MRI compared to men in both the unadjusted (OR-0.85, 95% CI=0.11-0.20, p-value <0.001) and after adjusting for BMI, age, marital status, hypertension, and transient ischemic attacks (TIA) (OR=0.15; 95%CI: 0.11-0.20). No other variables assessed had significant independent association with the receipt of a MRI. Conclusions: We found evidence of gender disparities in the receipt of MRI during hospitalization for stroke in patients in the Puerto Rico. Women were less likely to receive MRI compared to men. Further research on potential reasons for such dispairites, increasing awareness, and testing intervention as to decrease these potential disparities are needed
Cell walls of the dimorphic fungal pathogens Sporothrix schenckii and Sporothrix brasiliensis exhibit bilaminate structures and sloughing of extensive and intact layers
This work was supported by the Fundação Carlos Chagas de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), grants E-26/202.974/2015 and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), grants 229755/2013-5, Brazil. LMLB is a senior research fellow of CNPq and Faperj. NG acknowledged support from the Wellcome Trust (Trust (097377, 101873, 200208) and MRC Centre for Medical Mycology (MR/N006364/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD
Highlights from the Pierre Auger Observatory
The Pierre Auger Observatory is the world's largest cosmic ray observatory.
Our current exposure reaches nearly 40,000 km str and provides us with an
unprecedented quality data set. The performance and stability of the detectors
and their enhancements are described. Data analyses have led to a number of
major breakthroughs. Among these we discuss the energy spectrum and the
searches for large-scale anisotropies. We present analyses of our X
data and show how it can be interpreted in terms of mass composition. We also
describe some new analyses that extract mass sensitive parameters from the 100%
duty cycle SD data. A coherent interpretation of all these recent results opens
new directions. The consequences regarding the cosmic ray composition and the
properties of UHECR sources are briefly discussed.Comment: 9 pages, 12 figures, talk given at the 33rd International Cosmic Ray
Conference, Rio de Janeiro 201
The Pierre Auger Observatory III: Other Astrophysical Observations
Astrophysical observations of ultra-high-energy cosmic rays with the Pierre
Auger ObservatoryComment: Contributions to the 32nd International Cosmic Ray Conference,
Beijing, China, August 201
Antennas for the detection of radio emission pulses from cosmic-ray induced air showers at the Pierre Auger Observatory
The Pierre Auger Observatory is exploring the potential of the radio detection technique to study extensive air showers induced by ultra-high energy cosmic rays. The Auger Engineering Radio Array (AERA) addresses both technological and scientific aspects of the radio technique. A first phase of AERA has been operating since September 2010 with detector stations observing radio signals at frequencies between 30 and 80 MHz. In this paper we present comparative studies to identify and optimize the antenna design for the final configuration of AERA consisting of 160 individual radio detector stations. The transient nature of the air shower signal requires a detailed description of the antenna sensor. As the ultra-wideband reception of pulses is not widely discussed in antenna literature, we review the relevant antenna characteristics and enhance theoretical considerations towards the impulse response of antennas including polarization effects and multiple signal reflections. On the basis of the vector effective length we study the transient response characteristics of three candidate antennas in the time domain. Observing the variation of the continuous galactic background intensity we rank the antennas with respect to the noise level added to the galactic signal
The rapid atmospheric monitoring system of the Pierre Auger Observatory
The Pierre Auger Observatory is a facility built to detect air showers produced by cosmic rays above 10(17) eV. During clear nights with a low illuminated moon fraction, the UV fluorescence light produced by air showers is recorded by optical telescopes at the Observatory. To correct the observations for variations in atmospheric conditions, atmospheric monitoring is performed at regular intervals ranging from several minutes (for cloud identification) to several hours (for aerosol conditions) to several days (for vertical profiles of temperature, pressure, and humidity). In 2009, the monitoring program was upgraded to allow for additional targeted measurements of atmospheric conditions shortly after the detection of air showers of special interest, e. g., showers produced by very high-energy cosmic rays or showers with atypical longitudinal profiles. The former events are of particular importance for the determination of the energy scale of the Observatory, and the latter are characteristic of unusual air shower physics or exotic primary particle types. The purpose of targeted (or 'rapid') monitoring is to improve the resolution of the atmospheric measurements for such events. In this paper, we report on the implementation of the rapid monitoring program and its current status. The rapid monitoring data have been analyzed and applied to the reconstruction of air showers of high interest, and indicate that the air fluorescence measurements affected by clouds and aerosols are effectively corrected using measurements from the regular atmospheric monitoring program. We find that the rapid monitoring program has potential for supporting dedicated physics analyses beyond the standard event reconstruction
Identifying clouds over the Pierre Auger Observatory using infrared satellite data
We describe a new method of identifying night-time clouds over the Pierre Auger Observatory using infrared data from the Imager instruments on the GOES-12 and GOES-13 satellites. We compare cloud. identifications resulting from our method to those obtained by the Central Laser Facility of the Auger Observatory. Using our new method we can now develop cloud probability maps for the 3000 km(2) of the Pierre Auger Observatory twice per hour with a spatial resolution of similar to 2.4 km by similar to 5.5 km. Our method could also be applied to monitor cloud cover for other ground-based observatories and for space-based observatories. (C) 2013 Elsevier B.V. All rights reserved.The successful installation, commissioning, and operation of the
Pierre Auger Observatory would not have been possible without
the strong commitment and effort from the technical and adminis-
trative staff in Malargüe.
We are very grateful to the following agencies and organiza-
tions for financial support: Comisión Nacional de Energía Atómica,
Fundación Antorchas, Gobierno De La Provincia de Mendoza,
Municipalidad de Malargüe, NDM Holdings and Valle Las Leñas,
in gratitude for their continuing cooperation over land access,
Argentina; the Australian Research Council; Conselho Nacional de
Desenvolvimento Científico e Tecnológico (CNPq), Financiadora
de Estudos e Projetos (FINEP), Fundação de Amparo à Pesquisa do
Estado de Rio de Janeiro (FAPERJ), Fundação de Amparo à Pesquisa
do Estado de São Paulo (FAPESP), Ministério de Ciência e Tecnolo-
gia (MCT), Brazil; AVCR AV0Z10100502 and AV0Z10100522, GAAV
KJB100100904, MSMT-CR LA08016, LG11044, MEB111003,
MSM0021620859, LA08015, TACR TA01010517 and GA UK
119810, Czech Republic; Centre de Calcul IN2P3/CNRS, Centre Na-
tional de la Recherche Scientifique (CNRS), Conseil Régional Ile-de-
France, Département Physique Nucléaire et Corpusculaire (PNC-
IN2P3/CNRS), Département Sciences de l’Univers (SDU-INSU/
CNRS), France; Bundesministerium für Bildung und Forschung
(BMBF), Deutsche Forschungsgemeinschaft (DFG), Finanzministeri-
um Baden-Württemberg, Helmholtz-Gemeinschaft Deutscher
Forschungszentren (HGF), Ministerium für Wissenschaft und
Forschung, Nordrhein-Westfalen, Ministerium für Wissenschaft,
Forschung und Kunst, Baden-Württemberg, Germany; Istituto
Nazionale di Fisica Nucleare (INFN), Ministero dell’Istruzione,
dell’Università e della Ricerca (MIUR), Italy; Consejo Nacional de Ciencia y Tecnología (CONACYT), Mexico; Ministerie van Ond-
erwijs, Cultuur en Wetenschap, Nederlandse Organisatie voor Wet-
enschappelijk Onderzoek (NWO), Stichting voor Fundamenteel
Onderzoek der Materie (FOM), Netherlands; Ministry of Science
and Higher Education, Grant Nos. N N202 200239 and N N202
207238, Poland; Portuguese national funds and FEDER funds with-
in COMPETE - Programa Operacional Factores de Competitividade
through Fundação para a Ciência e a Tecnologia, Portugal; Roma-
nian Authority for Scientific Research ANCS, CNDI-UEFISCDI part-
nership projects nr.20/2012 and nr.194/2012, project nr.1/
ASPERA2/2012 ERA-NET and PN-II-RU-PD-2011-3-0145-17, Roma-
nia; Ministry for Higher Education, Science, and Technology, Slove-
nian Research Agency, Slovenia; Comunidad de Madrid, FEDER
funds, Ministerio de Ciencia e Innovación and Consolider-Ingenio
2010 (CPAN), Xunta de Galicia, Spain; The Leverhulme Foundation,
Science and Technology Facilities Council, United Kingdom;
Department of Energy, Contract Nos. DE-AC02-07CH11359, DE-
FR02-04ER41300, DE-FG02-99ER41107, National Science Founda-
tion, Grant No. 0450696, The Grainger Foundation USA; NAFO-
STED, Vietnam; Marie Curie-IRSES/EPLANET, European Particle
Physics Latin American Network, European Union 7th Framework
Program, Grant No. PIRSES-2009-GA-246806; and UNESCO.
We would like to thank the former Michigan Tech students:
Nathan Kelley-Hoskins, Kyle Luck and Arin Nelson for their impor-
tant contribution to the development of this paper. We would like
to thank NOAA for the GOES satellite data that we freely down-
loaded from their website. Also, we would like to mention in these
acknowledgments Dr. Steve Ackerman and Dr. Tony Schreiner for
very valuable conversationsPeer reviewe
The Pierre Auger Observatory IV: Operation and Monitoring
Technical reports on operations and monitoring of the Pierre Auger
ObservatoryComment: Constributions to 32nd International Cosmic Ray Conference, Beijing,
China, August 201
Techniques for measuring aerosol attenuation using the Central Laser Facility at the Pierre Auger Observatory
The Pierre Auger Observatory in Malargüe, Argentina, is designed to study the properties of ultra-high energy cosmic rays with energies above 10(18) eV. It is a hybrid facility that employs a Fluorescence Detector to perform nearly calorimetric measurements of Extensive Air Shower energies. To obtain reliable calorimetric information from the FD, the atmospheric conditions at the observatory need to be continuously monitored during data acquisition. In particular, light attenuation due to aerosols is an important atmospheric correction. The aerosol concentration is highly variable, so that the aerosol attenuation needs to be evaluated hourly. We use light from the Central Laser Facility, located near the center of the observatory site, having an optical signature comparable to that of the highest energy showers detected by the FD. This paper presents two procedures developed to retrieve the aerosol attenuation of fluorescence light from CLF laser shots. Cross checks between the two methods demonstrate that results from both analyses are compatible, and that the uncertainties are well understood. The measurements of the aerosol attenuation provided by the two procedures are currently used at the Pierre Auger Observatory to reconstruct air shower data
The Pierre Auger Observatory II: Studies of Cosmic Ray Composition and Hadronic Interaction models
Studies of the composition of the highest energy cosmic rays with the Pierre
Auger Observatory, including examination of hadronic physics effects on the
structure of extensive air showers.Comment: Contributions to the 32nd International Cosmic Ray Conference,
Beijing, China, August 201
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