IN PERPETVAM REI MEMORIAM: A epígrafe latina em honra de D. Luís de Menezes, Senhor de Ansião

A propósito da inscrição latina inserida no monumento levantado, em 1686, na vila de Ansião, por iniciativa do Senado local, em honra do Conde da Ericeira, traça-se uma panorâmica do que era na época esse lugar; conta-se da intervenção de D. Luís de Menezes para que o lugar fosse elevado à categoria de concelho: e faz-se o estudo epigráfico da inscrição. Essa análise permitiu também trazer mais alguma luz sobre a brilhante actividade do Conde da Ericeira. À propos du texte latin qui figure sur un monument érigé, en 1686, à Ansião (localité du Centre de Portugal, district de Leiria), en honneur de Luís de Menezes, Comte d’Ericeira et Conseiller d’État, on essaie de dresser un portrait sur l’activité de cette localité à l’époque et d’évoquer les raisons par lesquelles lui a été atribué le statut de municipe. On fait l’étude épigraphique du texte, ce qui a permis, d’autre part, de mieux connaître l’œuvre de ce notable homme d’État

IN PERPETVAM REI MEMORIAM: A epígrafe latina em honra de D. Luís de Menezes, Senhor de Ansião

A propósito da inscrição latina inserida no monumento levantado, em 1686, na vila de Ansião, por iniciativa do Senado local, em honra do Conde da Ericeira, traça-se uma panorâmica do que era na época esse lugar; conta-se da intervenção de D. Luís de Menezes para que o lugar fosse elevado à categoria de concelho: e faz-se o estudo epigráfico da inscrição. Essa análise permitiu também trazer mais alguma luz sobre a brilhante actividade do Conde da Ericeira. À propos du texte latin qui figure sur un monument érigé, en 1686, à Ansião (localité du Centre de Portugal, district de Leiria), en honneur de Luís de Menezes, Comte d’Ericeira et Conseiller d’État, on essaie de dresser un portrait sur l’activité de cette localité à l’époque et d’évoquer les raisons par lesquelles lui a été atribué le statut de municipe. On fait l’étude épigraphique du texte, ce qui a permis, d’autre part, de mieux connaître l’œuvre de ce notable homme d’État

Da anomia ao estigma

Estudos de caso de instituições totais, segregativas e estigmatizantes (prisões, hospitais psiquiátricos, centros de reeducação), cuja finalidade é terminal e/ou normalizante e dos universos anómicos nela internados.info:eu-repo/semantics/publishedVersio

Portuguese guide lines for the use of biological agents in rheumatoid arthritis - october 2011 update

The authors present the revised version of the Portuguese Society of Rheumatology (SPR) guidelines for the treatment of Rheumatoid Arthritis (RA) with biological therapies. In these guidelines the criteria for introduction and maintenance of biological agents are discussed as well as the contraindications and procedures in the case of non-responders. Biological treatment (with a tumour necrosis factor antagonist, abatacept or tocilizumab) should be considered in RA patients with a disease activity score 28 (DAS 28) equal to or greater than 3.2 des pite treatment with at least 20mg-weekly-dose of methotrexate (MTX) for at least 3 months or, if such treatment is not possible, after 3 months of other conventional disease modifying drug or combination therapy. A DAS 28 score between 2.6 and 3.2 with a significant functional or radiological deterioration under treatment with conventional regi -mens could also constitute an indication for biological treatment. The treatment goal should be remission or, if that is not achievable, at least a low disease activity, defined by a DAS28 lower than 3.2,without significative functional or radiological worsening. The response criteria, at the end of the first 3 months of treatment, are a decrease of at least 0.6 in the DAS28 score. After 6 months of treatment res ponse criteria is defined as a decrease greater than 1.2 in the DAS28 score. Non-responders, in accordance to the Rheumatologist's clinical opi -nion, should try a switch to another biological agent (tumour necrosis factor antagonist, abatacept, rituxi mab or tocilizumab).publishersversionpublishe

Characterisation of microbial attack on archaeological bone

As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved