84 research outputs found
Novel Biomarkers for Coronary Restenosis Occurrence After Drug-Eluting Stent Implantation in Patients With Diabetes Having Stable Coronary Artery Disease
Glacial geomorphology of the High Gredos Massif: Gredos and Pinar valleys (Iberian Central System, Spain)
We present a detailed geomorphological map of the landform assemblages originated by the two major paleoglaciers of the Sierra de Gredos mountain range in the Spanish Iberian Central System. Based on previous works, our map focused on the features formed by Gredos and Pinar paleoglaciers during the last glaciation and subsequent glacial events. Based on a remote sensing analysis and exhaustive field surveys, we identified with great accuracy the local distribution of glacial, periglacial, mass movement, structural, fluvial, and lacustrine features. We recognized three main glacial geomorphological formations representing: (i) the maximum glacial extension reached (peripheral deposits); (ii) the culmination of glacial conditions (principal moraines) and (iii) the local glacial withdrawal (internal deposits). Our map offers a renewed spatial framework on which to conduct higher-resolution glacial chronologies, especially of Late Glacial and Holocene glacial activity, providing key information for performing future paleoclimatic reconstructions of the northern hemisphere mid-latitudes
Global agricultural productivity is threatened by increasing pollinator dependence without a parallel increase in crop diversification
The global increase in the proportion of land cultivated with pollinator-dependent crops implies increased reliance on pollination services. Yet agricultural practices themselves can profoundly affect pollinator supply and pollination. Extensive monocultures are associated with a limited pollinator supply and reduced pollination, whereas agricultural diversification can enhance both. Therefore, areas where agricultural diversity has increased, or at least been maintained, may better sustain high and more stable productivity of pollinator-dependent crops. Given that >80% of all crops depend, to varying extents, on insect pollination, a global increase in agricultural pollinator dependence over recent decades might have led to a concomitant increase in agricultural diversification. We evaluated whether an increase in the area of pollinator-dependent crops has indeed been associated with an increase in agricultural diversity, measured here as crop diversity, at the global, regional, and country scales for the period 1961–2016. Globally, results show a relatively weak and decelerating rise in agricultural diversity over time that was largely decoupled from the strong and continually increasing trend in agricultural dependency on pollinators. At regional and country levels, there was no consistent relationship between temporal changes in pollinator dependence and crop diversification. Instead, our results show heterogeneous responses in which increasing pollinator dependence for some countries and regions has been associated with either an increase or a decrease in agricultural diversity. Particularly worrisome is a rapid expansion of pollinator-dependent oilseed crops in several countries of the Americas and Asia that has resulted in a decrease in agricultural diversity. In these regions, reliance on pollinators is increasing, yet agricultural practices that undermine pollination services are expanding. Our analysis has thereby identified world regions of particular concern where environmentally damaging practices associated with large-scale, industrial agriculture threaten key ecosystem services that underlie productivity, in addition to other benefits provided by biodiversity.Fil: Aizen, Marcelo Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; ArgentinaFil: Aguiar, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura. Universidad de Buenos Aires. Facultad de Agronomía. Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura; ArgentinaFil: Biesmeijer, Jacobus C.. Leiden University; Países Bajos. Naturalis Biodiversity Center; Países BajosFil: Garibaldi, Lucas Alejandro. Universidad Nacional de Río Negro. Sede Andina. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; ArgentinaFil: Inouye, David W.. University of Maryland; Estados Unidos. Rocky Mountain Biological Laboratory; Estados UnidosFil: Jung, Chuleui. Andong National University; Corea del SurFil: Martins, Dino J.. University of Princeton; Estados UnidosFil: Medel, Rodrigo. Universidad de Chile; ChileFil: Morales, Carolina Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; ArgentinaFil: Ngo, Hien. UN Campus Platz der Vereinten Nationen. Intergovernmental Science Policy Platform on Biodiversity and Ecosystem Services; AlemaniaFil: Pauw, Anton. Stellenbosch University; SudáfricaFil: Paxton, Robert J. Martin Luther University Halle Wittenberg; Alemania. German Centre for Integrative Biodiversity Research; AlemaniaFil: Sáez, Agustín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; ArgentinaFil: Seymour, Colleen L.. South African National Biodiversity Institute; Sudáfrica. University of Cape Town; Sudáfric
The Spanish Infrared Camera onboard the EUSO-BALLOON (CNES) flight on August 24, 2014
The EUSO-Balloon (CNES) campaign was held during Summer 2014 with a launch on August
24. In the gondola, next to the Photo Detector Module (PDM), a completely isolated Infrared
camera was allocated. Also, a helicopter which shooted flashers flew below the balloon. We have
retrieved the Cloud Top Height (CTH) with the IR camera, and also the optical depth of the nonclear atmosphere have been inferred with two approaches: The first one is with the comparison of the brightness temperature of the cloud and the real temperature obtained after the pertinent
corrections. The second one is by measuring the detected signal from the helicopter flashers by the IR Camera, considering the energy of the flashers and the location of the helicopter
Earliest Known Use of Marine Resources by Neanderthals
Numerous studies along the northern Mediterranean borderland have documented the use of shellfish by Neanderthals but none of these finds are prior to Marine Isotopic Stage 3 (MIS 3). In this paper we present evidence that gathering and consumption of mollusks can now be traced back to the lowest level of the archaeological sequence at Bajondillo Cave (Málaga, Spain), dated during the MIS 6. The paper describes the taxonomical and taphonomical features of the mollusk assemblages from this level Bj19 and briefly touches upon those retrieved in levels Bj18 (MIS 5) and Bj17 (MIS 4), evidencing a continuity of the shellfishing activity that reaches to MIS 3. This evidence is substantiated on 29 datings through radiocarbon, thermoluminescence and U series methods. Obtained dates and paleoenvironmental records from the cave include isotopic, pollen, lithostratigraphic and sedimentological analyses and they are fully coherent with paleoclimate conditions expected for the different stages. We conclude that described use of shellfish resources by Neanderthals (H. neanderthalensis) in Southern Spain started ∼150 ka and were almost contemporaneous to Pinnacle Point (South Africa), when shellfishing is first documented in archaic modern humans
The atmospheric science of JEM-EUSO
An Atmospheric Monitoring System (AMS) is critical suite of instruments for JEM-EUSO whose aim is to detect Ultra-High Energy Cosmic Rays (UHECR) and (EHECR) from Space. The AMS
comprises an advanced space qualified infrared camera and a LIDAR with cross checks provided by a ground-based and airborne Global Light System Stations. Moreover the Slow Data Mode of JEM-EUSO has been proven crucial for the UV background analysis by comparing the UV and IR images. It will also contribute to the investigation of atmospheric effects seen in the data from the GLS or even to our understanding of Space Weather
The Prados del Cervunal morainic complex: Evidence of a MIS 2 glaciation in the Iberian Central System synchronous to the global LGM
© 2023 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND licenseThe area of Prados del Cervunal (PC) is an intra-morainic topographic depression located at 1800 m asl in the divide or interfluve between Garganta de Gredos and Garganta del Pinar valleys (Central Gredos; Iberian Central System, ICS). Both valleys, along with the adjacent Hoya Nevada, were occupied by glaciers during the Upper Pleistocene, leading to the development of the Prados del Cervunal moraine complexes studied in this work. Using cartographic methods and morphostratigraphic analysis, the three main glacial formations established in the Regional Chrono-Evolutionary Pattern for the ICS, Peripheral Deposits (PD), Principal Moraine (PM) and Internal Deposits (ID), have been identified and mapped in this area. The chronology of these formations has been implemented by Cosmic Ray Exposure (CRE) techniques using 10Be (new data) and 26Cl (previous data, recalculated in this work) in samples from morainic boulders. With these data, the following chrono-evolutionary sequence has been established: (stage 1) local-Maximum Ice Extent (MIE), dated in 25.0 ± 1.4 ka and corresponding to the maximum age obtained in these paleoglaciers; (stage 2) period of oscillations around the MIE, corresponding to the development of the PD Formation between ∼25 ka and ∼21 ka; (stage 3) period of readvance and stabilisation, dated after ∼21 ka (average age obtained for the PD moraines attached to PM moraines) and previous to ∼18 (minimum age obtained for a main crest of the PM formation); and (stage 4) onset of deglaciation dated around to ∼18 ka (average of ages obtained for the first main crest of the ID formation). During the stages of maximum ice expansion, these three glaciers formed an Ice field whose tongues were interconnected on the PC flat by an ice transfluence system (stages 1 and 2, Plateau Glacier Period). In later stages, the ice masses were partitioned, giving rise to valley glaciers and large moraines forming morainic complexes like those of PC (stages 2, 3 and 4, Valley Glaciers Period). The local MIE and onset of deglaciation stages in this area show a good fit with the ages stablished to global level for the global Last Glacial Maximum (LGM) and the onset of the Last Glacial Termination (Termination I). They also show good correlation at local (with other areas of the ICS), peninsular (with other Iberian mountains) and continental (some areas of the Alps and mountains of Central Europe) level. Finally, this evolutionary sequence and its correlations allowed us to adjust and validate some units of the Regional Chrono-Evolutionary Pattern model and propose the Gredos-Pinar-Cabeza Nevada glacial system as benchmark for the glaciation of Marine Isotope Stage (MIS) 2 in the Iberian Peninsula.This work was supported by the Spanish Ministry of Science and Innovation (project PID2020-117685 GB-I00), Castilla-La Mancha University (UCLM, project 2023-GRIN-34112), ANID FONDECYT postdoctoral #3220537, ANID BASAL CHIC #FB210018 and ANID FONDECYT Regular #1220550. The ASTER AMS national facility (CEREGE, Aix-en-Provence) is supported by the INSU/CNRS, and IRD. The authors acknowledge the help and assistance received from the Sierra de Gredos Regional Park (Environmental Department of the Junta de Castilla y León, JCyL) and to the “Guarderia” (Staff of surveillance and control) of the Gredos Regional Reserve for their remarkable help in the fieldworks.Peer reviewe
Use of tocilizumab in kidney transplant recipients with COVID-1
Acute respiratory distress syndrome associated with coronavirus infection is related to a cytokine storm with large interleukin-6 (IL-6) release. The IL-6-receptor blocker tocilizumab may control the aberrant host immune response in patients with coronavirus disease 2019 (COVID-19) . In this pandemic, kidney transplant (KT) recipients are a high-risk population for severe infection and showed poor outcomes. We present a multicenter cohort study of 80 KT patients with severe COVID-19 treated with tocilizumab during hospital admission. High mortality rate was identified (32.5%), related with older age (hazard ratio [HR] 3.12 for those older than 60 years, P = .039). IL-6 and other inflammatory markers, including lactic acid dehydrogenase, ferritin, and D-dimer increased early after tocilizumab administration and their values were higher in nonsurvivors. Instead, C-reactive protein (CRP) levels decreased after tocilizumab, and this decrease positively correlated with survival (mean 12.3 mg/L in survivors vs. 33 mg/L in nonsurvivors). Each mg/L of CRP soon after tocilizumab increased the risk of death by 1% (HR 1.01 [confidence interval 1.004-1.024], P = .003). Although patients who died presented with worse respiratory situation at admission, this was not significantly different at tocilizumab administration and did not have an impact on outcome in the multivariate analysis. Tocilizumab may be effective in controlling cytokine storm in COVID-19 but randomized trials are needed
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